| EGFR | EGFR | TK | 5gtz | A | A | n-[5-[[5-chloranyl-4-[(2-propan-2-ylsulfonylphenyl)amino]pyrimidin-2-yl]amino]-2-(4-ethylpiperazin-1-yl)-4-methoxy-phenyl]prop-2-enamide | Human | 8365 | 0.49 | |
| EGFR | EGFR | TK | 5gtz | A | B | n-[5-[[5-chloranyl-4-[(2-propan-2-ylsulfonylphenyl)amino]pyrimidin-2-yl]amino]-2-(4-ethylpiperazin-1-yl)-4-methoxy-phenyl]prop-2-enamide | Human | 8361 | 0.49 | |
| EGFR | EGFR | TK | 7aei | A | | 5-chloranyl-~{n}2-[4-[4-(dimethylamino)piperidin-1-yl]-2-methoxy-5-(1-methylpyrazol-4-yl)phenyl]-~{n}4-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamine | Human | 13619 | 0.40 | |
| DCLK1 | DCAMKL | CAMK | 5jzn | A | | 5-chloro-n-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-n'-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine | Human | 6986 | 0.53 | |
| FES | Fer | TK | 4e93 | A | B | 5-chloro-n-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-n'-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine | Human | 2809 | 0.53 | |
| DCLK1 | DCAMKL | CAMK | 5jzn | B | | 5-chloro-n-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-n'-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine | Human | 6982 | 0.53 | |
| FES | Fer | TK | 4e93 | A | A | 5-chloro-n-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-n'-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine | Human | 2816 | 0.53 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6bql | A | | 2-({5-chloro-2-[(2-methoxy-4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl}amino)-n-methylbenzamide | Human | 9061 | 0.40 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6brc | B | | 5-chloro-n~2~-{4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl}-n~4~-[2-(dimethylphosphoryl)phenyl]pyrimidine-2,4-diamine | Human | 9060 | 0.40 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6brc | A | | 5-chloro-n~2~-{4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl}-n~4~-[2-(dimethylphosphoryl)phenyl]pyrimidine-2,4-diamine | Human | 9062 | 0.40 | |
| IGF1R | InsR | TK | 5fxr | A | A | 5-chloranyl-4-imidazo[1,2-a]pyridin-3-yl-n-(3-methyl-1-piperidin-4-yl-pyrazol-4-yl)pyrimidin-2-amine | Human | 7095 | 0.40 | |
| IGF1R | InsR | TK | 5fxr | A | B | 5-chloranyl-4-imidazo[1,2-a]pyridin-3-yl-n-(3-methyl-1-piperidin-4-yl-pyrazol-4-yl)pyrimidin-2-amine | Human | 7094 | 0.40 | |
| ALK | ALK | TK | 4mkc | A | A | 5-chloro-n~2~-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-n~4~-[2-(propan-2-ylsulfonyl)phenyl]pyrimidine-2,4-diamine | Human | 5401 | 1.00 | |
| ALK | ALK | TK | 2xb7 | A | | 5-chloro-n-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-n'-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine | Human | 5365 | 0.53 | |
| ALK | ALK | TK | 4z55 | A | B | n~6~-[5-methyl-4-(1-methylpiperidin-4-yl)-2-(propan-2-yloxy)phenyl]-n~4~-[2-(propan-2-ylsulfonyl)phenyl]-2h-pyrazolo[3,4-d]pyrimidine-4,6-diamine | Human | 6392 | 0.61 | |
| ALK | ALK | TK | 4z55 | A | A | n~6~-[5-methyl-4-(1-methylpiperidin-4-yl)-2-(propan-2-yloxy)phenyl]-n~4~-[2-(propan-2-ylsulfonyl)phenyl]-2h-pyrazolo[3,4-d]pyrimidine-4,6-diamine | Human | 6393 | 0.61 | |
| ALK | ALK | TK | 4mkc | A | B | 5-chloro-n~2~-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-n~4~-[2-(propan-2-ylsulfonyl)phenyl]pyrimidine-2,4-diamine | Human | 5386 | 1.00 | |
| ALK | ALK | TK | 5imx | A | | 5-chloro-n~2~-{5-methyl-4-(1-methylpiperidin-4-yl)-2-[(propan-2-yl)oxy]phenyl}-n~4~-{1-methyl-3-[(propan-2-yl)sulfonyl]-1h-pyrazol-4-yl}pyrimidine-2,4-diamine | Human | 6604 | 0.63 | |
Match: