Searching for structures with analogs of Cobimetinib.
Search results (3 entries covering 2 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MAP2K1 | STE7 | STE | 4anb | A | [3-(aminomethyl)-3-oxidanyl-azetidin-1-yl]-[3,4-bis(fluoranyl)-2-[(2-fluoranyl-4-iodanyl-phenyl)amino]phenyl]methanone | Human | 3302 | 0.65 | |||
| MAP2K1 | STE7 | STE | 4an2 | A | B | [3,4-bis(fluoranyl)-2-[(2-fluoranyl-4-iodanyl-phenyl)amino]phenyl]-[3-oxidanyl-3-[(2s)-piperidin-2-yl]azetidin-1-yl]methanone | Human | 3326 | 1.00 | ||
| MAP2K1 | STE7 | STE | 4an2 | A | A | [3,4-bis(fluoranyl)-2-[(2-fluoranyl-4-iodanyl-phenyl)amino]phenyl]-[3-oxidanyl-3-[(2s)-piperidin-2-yl]azetidin-1-yl]methanone | Human | 3309 | 1.00 |
Cobimetinib
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