Searching for structures with analogs of -.
Search results (8 entries covering 2 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| JAK1 | JakA | TK | 6smb | A | A | ~{n}-[3-[2-[(3-methoxy-1-methyl-pyrazol-4-yl)amino]-5-methyl-pyrimidin-4-yl]-1~{h}-indol-7-yl]-2-methyl-pyridine-3-carboxamide | Human | 12246 | 0.41 | ||
| JAK1 | JakA | TK | 6ggh | B | A | ~{n}-[5-methyl-4-[7-[[(2~{r})-2-(4-methylpiperazin-1-yl)propanoyl]amino]-1~{h}-indol-3-yl]pyrimidin-2-yl]cyclopropanecarboxamide | Human | 11089 | 0.47 | ||
| JAK1 | JakA | TK | 6smb | A | B | ~{n}-[3-[2-[(3-methoxy-1-methyl-pyrazol-4-yl)amino]-5-methyl-pyrimidin-4-yl]-1~{h}-indol-7-yl]-2-methyl-pyridine-3-carboxamide | Human | 12247 | 0.41 | ||
| JAK1 | JakA | TK | 6smb | B | A | ~{n}-[3-[2-[(3-methoxy-1-methyl-pyrazol-4-yl)amino]-5-methyl-pyrimidin-4-yl]-1~{h}-indol-7-yl]-2-methyl-pyridine-3-carboxamide | Human | 12244 | 0.41 | ||
| JAK1 | JakA | TK | 6smb | B | B | ~{n}-[3-[2-[(3-methoxy-1-methyl-pyrazol-4-yl)amino]-5-methyl-pyrimidin-4-yl]-1~{h}-indol-7-yl]-2-methyl-pyridine-3-carboxamide | Human | 12243 | 0.41 | ||
| JAK1 | JakA | TK | 6ggh | B | B | ~{n}-[5-methyl-4-[7-[[(2~{r})-2-(4-methylpiperazin-1-yl)propanoyl]amino]-1~{h}-indol-3-yl]pyrimidin-2-yl]cyclopropanecarboxamide | Human | 11086 | 0.47 | ||
| JAK1 | JakA | TK | 6ggh | A | A | ~{n}-[5-methyl-4-[7-[[(2~{r})-2-(4-methylpiperazin-1-yl)propanoyl]amino]-1~{h}-indol-3-yl]pyrimidin-2-yl]cyclopropanecarboxamide | Human | 11087 | 0.47 | ||
| JAK1 | JakA | TK | 6ggh | A | B | ~{n}-[5-methyl-4-[7-[[(2~{r})-2-(4-methylpiperazin-1-yl)propanoyl]amino]-1~{h}-indol-3-yl]pyrimidin-2-yl]cyclopropanecarboxamide | Human | 11088 | 0.47 |
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