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Searching for structures with analogs of -.

Search results (8 entries covering 6 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
Pik3cd (p110d)PIKAtypical7r26A5-[2,6-di(morpholin-4-yl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amineMouse142310.48
PIK3CA (p110a)PIKAtypical7tz7AA(4s,5r)-3-[2'-amino-2-(morpholin-4-yl)-4'-(trifluoromethyl)[4,5'-bipyrimidin]-6-yl]-4-(hydroxymethyl)-5-methyl-1,3-oxazolidin-2-oneHuman142231.00
PIK3CG (p110g)PIKAtypical5jhaA[1-{4-[6-amino-4-(trifluoromethyl)pyridin-3-yl]-6-(morpholin-4-yl)pyrimidin-2-yl}-3-(chloromethyl)azetidin-3-yl]methanolHuman92460.45
PIK3CG (p110g)PIKAtypical3sd5A5-[2,6-di(morpholin-4-yl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amineHuman92430.48
Pik3cd (p110d)PIKAtypical7r2bA(4~{s})-3-[6-[2-azanyl-4-(trifluoromethyl)pyrimidin-5-yl]-2-morpholin-4-yl-pyrimidin-4-yl]-4-methyl-1,3-oxazolidin-2-oneMouse142300.74
PIK3CA (p110a)PIKAtypical7tz7AB(4s,5r)-3-[2'-amino-2-(morpholin-4-yl)-4'-(trifluoromethyl)[4,5'-bipyrimidin]-6-yl]-4-(hydroxymethyl)-5-methyl-1,3-oxazolidin-2-oneHuman142221.00
PIK3CG (p110g)PIKAtypical5oq4AA5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amineHuman92440.40
PIK3CG (p110g)PIKAtypical5oq4AB5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amineHuman92030.40
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