Searching for structures with analogs of -.
Search results (8 entries covering 6 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Pik3cd (p110d) | PIK | Atypical | 7r26 | A | 5-[2,6-di(morpholin-4-yl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine | Mouse | 14231 | 0.48 | |||
| PIK3CG (p110g) | PIK | Atypical | 5jha | A | [1-{4-[6-amino-4-(trifluoromethyl)pyridin-3-yl]-6-(morpholin-4-yl)pyrimidin-2-yl}-3-(chloromethyl)azetidin-3-yl]methanol | Human | 9246 | 0.45 | |||
| Pik3cd (p110d) | PIK | Atypical | 7r2b | A | (4~{s})-3-[6-[2-azanyl-4-(trifluoromethyl)pyrimidin-5-yl]-2-morpholin-4-yl-pyrimidin-4-yl]-4-methyl-1,3-oxazolidin-2-one | Mouse | 14230 | 0.74 | |||
| PIK3CA (p110a) | PIK | Atypical | 7tz7 | A | A | (4s,5r)-3-[2'-amino-2-(morpholin-4-yl)-4'-(trifluoromethyl)[4,5'-bipyrimidin]-6-yl]-4-(hydroxymethyl)-5-methyl-1,3-oxazolidin-2-one | Human | 14223 | 1.00 | ||
| PIK3CG (p110g) | PIK | Atypical | 3sd5 | A | 5-[2,6-di(morpholin-4-yl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine | Human | 9243 | 0.48 | |||
| PIK3CG (p110g) | PIK | Atypical | 5oq4 | A | A | 5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine | Human | 9244 | 0.40 | ||
| PIK3CG (p110g) | PIK | Atypical | 5oq4 | A | B | 5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine | Human | 9203 | 0.40 | ||
| PIK3CA (p110a) | PIK | Atypical | 7tz7 | A | B | (4s,5r)-3-[2'-amino-2-(morpholin-4-yl)-4'-(trifluoromethyl)[4,5'-bipyrimidin]-6-yl]-4-(hydroxymethyl)-5-methyl-1,3-oxazolidin-2-one | Human | 14222 | 1.00 |
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