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Searching for structures with analogs of
Dabrafenib
.
Search results (16 entries covering 6 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
Similarity (MFP)
File
BRAF
RAF
TKL
5csw
A
dabrafenib
Human
6433
1.00
BRAF
RAF
TKL
4xv2
A
dabrafenib
Human
6213
1.00
BRAF
RAF
TKL
7p3v
A
~{n}-[3-[5-(2-azanylpyrimidin-4-yl)-2-[(3~{s})-morpholin-3-yl]-1,3-thiazol-4-yl]-2-fluoranyl-phenyl]-2,5-bis(fluoranyl)benzenesulfonamide
Human
13961
0.53
BRAF
RAF
TKL
5hie
D
A
dabrafenib
Human
6510
1.00
BRAF
RAF
TKL
5hie
A
A
dabrafenib
Human
6516
1.00
BRAF
RAF
TKL
4xv3
A
n'-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}-n-ethyl-n-methylsulfuric diamide
Human
6217
0.70
BRAF
RAF
TKL
5hie
C
B
dabrafenib
Human
6507
1.00
BRAF
RAF
TKL
5hie
B
B
dabrafenib
Human
6505
1.00
BRAF
RAF
TKL
5csw
B
dabrafenib
Human
6431
1.00
BRAF
RAF
TKL
5hie
C
A
dabrafenib
Human
6513
1.00
BRAF
RAF
TKL
5hie
D
B
dabrafenib
Human
6514
1.00
BRAF
RAF
TKL
6v2u
B
dabrafenib
Human
13031
1.00
BRAF
RAF
TKL
5hie
B
A
dabrafenib
Human
6509
1.00
BRAF
RAF
TKL
6v2u
A
dabrafenib
Human
13034
1.00
BRAF
RAF
TKL
4xv2
B
dabrafenib
Human
6219
1.00
BRAF
RAF
TKL
5hie
A
B
dabrafenib
Human
6508
1.00
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Dabrafenib
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