| Abl1 (ABL1) | Abl | TK | 1m52 | A | | 6-(2,6-dichloro-phenyl)-8-methyl-2-(3-methylsulfanyl-phenylamino)-8h-pyrido[2,3-d]pyrimidin-7-one | Mouse | 5720 | 0.60 | |
| LCK | Src | TK | 3kmm | A | | 3-(2,6-dichlorophenyl)-7-({4-[2-(diethylamino)ethoxy]phenyl}amino)-1-methyl-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 2265 | 0.58 | |
| Abl1 (ABL1) | Abl | TK | 1m52 | B | | 6-(2,6-dichloro-phenyl)-8-methyl-2-(3-methylsulfanyl-phenylamino)-8h-pyrido[2,3-d]pyrimidin-7-one | Mouse | 5715 | 0.60 | |
| BTK | Tec | TK | 3pj2 | A | | 2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-6-(4-fluorophenoxy)-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 2911 | 0.65 | |
| ABL1 | Abl | TK | 2hzi | A | A | 6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1102 | 0.61 | |
| EPHA2 (EphA2) | Eph | TK | 5ia3 | A | A | 6-(2,6-dichloro-phenyl)-8-methyl-2-(3-methylsulfanyl-phenylamino)-8h-pyrido[2,3-d]pyrimidin-7-one | Human | 7193 | 0.60 | |
| EPHA2 (EphA2) | Eph | TK | 5ia3 | A | B | 6-(2,6-dichloro-phenyl)-8-methyl-2-(3-methylsulfanyl-phenylamino)-8h-pyrido[2,3-d]pyrimidin-7-one | Human | 7184 | 0.60 | |
| ABL1 | Abl | TK | 2hzi | A | B | 6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1087 | 0.61 | |
| ABL1 | Abl | TK | 2hzi | B | A | 6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1108 | 0.61 | |
| ABL1 | Abl | TK | 2g2h | B | | 6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1089 | 0.62 | |
| ABL1 | Abl | TK | 1opl | B | | 6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1086 | 0.62 | |
| ABL1 | Abl | TK | 2hzi | B | B | 6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1055 | 0.61 | |
| ABL1 | Abl | TK | 1opl | A | | 6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1104 | 0.62 | |
| ABL1 | Abl | TK | 2fo0 | A | | 6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1073 | 0.62 | |
| SYK | Syk | TK | 3tud | A | | n-{4-methyl-3-[8-methyl-7-oxo-2-(phenylamino)-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl]phenyl}-3-(trifluoromethyl)benzamide | Human | 1176 | 0.41 | |
| WEE1 (Wee1) | WEE | Other | 5vc5 | A | B | 6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 8333 | 1.00 | |
| WEE1 (Wee1) | WEE | Other | 5vc5 | A | A | 6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 8332 | 1.00 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fsf | A | | 3-(2,6-dichlorophenyl)-7-({4-[(diethylamino)methoxy]phenyl}amino)-1-methyl-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 5097 | 0.48 | |
| BTK | Tec | TK | 3pj1 | A | | 3-(2,6-dichlorophenyl)-7-({4-[2-(diethylamino)ethoxy]phenyl}amino)-1-methyl-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 2904 | 0.58 | |
| Abl1 (ABL1) | Abl | TK | 1opk | A | | 6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Mouse | 5709 | 0.62 | |
| ABL1 | Abl | TK | 2g2h | A | | 6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1106 | 0.62 | |
Match: