KLIFS - the structural kinase database

Searching for structures with analogs of -.

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
CDK8	CDK	CMGC	4f7j	A	A	1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-(2-hydroxyethyl)urea	Human	3842	0.40
MAPK14 (p38a)	MAPK	CMGC	2yis	A		1-[3-tert-butyl-1-(3-chloro-4-hydroxyphenyl)-1h-pyrazol-5-yl]-3-{2-[(3-{2-[(2-hydroxyethyl)sulfanyl]phenyl}[1,2,4]triazolo[4,3-a]pyridin-6-yl)sulfanyl]benzyl}urea	Human	5240	1.00
MAPK14 (p38a)	MAPK	CMGC	2yix	A		1-ethyl-3-(2-{[3-(1-methylethyl)[1,2,4]triazolo[4,3-a]pyridin-6-yl]sulfanyl}benzyl)urea	Human	5143	0.41
MAPK14 (p38a)	MAPK	CMGC	2yiw	A		1-(3-tert-butyl-1-phenyl-1h-pyrazol-5-yl)-3-(2-{[3-(1-methylethyl)[1,2,4]triazolo[4,3-a]pyridin-6-yl]sulfanyl}benzyl)urea	Human	4988	0.62
CDK8	CDK	CMGC	4f7j	A	B	1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-(2-hydroxyethyl)urea	Human	3843	0.40