Searching for structures with analogs of -.

Search results (28 entries covering 11 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
EPHA2 (EphA2)EphTK5ia0BBalisertibHuman71790.70
EPHA2 (EphA2)EphTK5ia0CAalisertibHuman71860.70
AURKA (AurA)AurOther3h10D9-chloro-7-(2,6-difluorophenyl)-n-{4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-5h-pyrimido[5,4-d][2]benzazepin-2-amineHuman20590.79
AURKA (AurA)AurOther3h10B9-chloro-7-(2,6-difluorophenyl)-n-{4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-5h-pyrimido[5,4-d][2]benzazepin-2-amineHuman19880.79
AURKA (AurA)AurOther2wtvDB4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acidHuman20761.00
AURKA (AurA)AurOther3unzA4-({4-[(2-fluorophenyl)amino]pyrimidin-2-yl}amino)benzoic acidHuman19720.42
AURKA (AurA)AurOther2wtvCA4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acidHuman20171.00
AURKA (AurA)AurOther3h10A9-chloro-7-(2,6-difluorophenyl)-n-{4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-5h-pyrimido[5,4-d][2]benzazepin-2-amineHuman20090.79
AURKA (AurA)AurOther3uokB4-({4-[(2-chlorophenyl)amino]-5-fluoropyrimidin-2-yl}amino)benzoic acidHuman20470.50
AURKA (AurA)AurOther3unzB4-({4-[(2-fluorophenyl)amino]pyrimidin-2-yl}amino)benzoic acidHuman20490.42
AURKA (AurA)AurOther2wtvCB4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acidHuman20161.00
AURKA (AurA)AurOther2x81A4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acidHuman19661.00
AURKA (AurA)AurOther2wtvAA4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acidHuman20561.00
AURKA (AurA)AurOther2wtvBB4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acidHuman20571.00
AURKA (AurA)AurOther3uokA4-({4-[(2-chlorophenyl)amino]-5-fluoropyrimidin-2-yl}amino)benzoic acidHuman20540.50
AURKA (AurA)AurOther2wtvDA4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acidHuman20781.00
AURKA (AurA)AurOther2wtvBA4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acidHuman20371.00
EPHA2 (EphA2)EphTK5ia0ABalisertibHuman71710.70
EPHA2 (EphA2)EphTK5ia0BAalisertibHuman71740.70
EPHA2 (EphA2)EphTK5ia0AAalisertibHuman71690.70
AURKA (AurA)AurOther2wtwA4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acidHuman19561.00
AURKA (AurA)AurOther3uo5A4-{[4-(phenylamino)pyrimidin-2-yl]amino}benzoic acidHuman20450.40
AURKA (AurA)AurOther2wtvAB4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acidHuman19971.00
MAPK1 (Erk2)MAPKCMGC4fv4AB9-(dimethylamino)-2-[(3-hydroxyphenyl)amino]-5,6-dihydrothieno[3,4-h]quinazoline-7-carbonitrileHuman25580.40
EPHA2 (EphA2)EphTK5ia0CBalisertibHuman71750.70
EPHA2 (EphA2)EphTK5ia1A4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acidHuman71911.00
CDK2CDKCMGC3unjA4-{[4-(phenylamino)pyrimidin-2-yl]amino}benzoic acidHuman44980.40
MAPK1 (Erk2)MAPKCMGC4fv4AA9-(dimethylamino)-2-[(3-hydroxyphenyl)amino]-5,6-dihydrothieno[3,4-h]quinazoline-7-carbonitrileHuman26230.40