Searching for structures with analogs of -.
Search results (12 entries covering 11 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BTK | Tec | TK | 3pj2 | A | 2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-6-(4-fluorophenoxy)-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 2911 | 0.44 | |||
| MAPK14 (p38a) | MAPK | CMGC | 3fmn | A | A | 6-(2,4-difluorophenoxy)-n-(tetrahydro-2h-pyran-4-yl)-1h-pyrazolo[3,4-d]pyrimidin-3-amine | Human | 5196 | 0.49 | ||
| MAPK14 (p38a) | MAPK | CMGC | 3fly | A | 6-(2,4-difluorophenoxy)-8-methyl-2-[(1-methylethyl)amino]pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 5113 | 0.68 | |||
| MAPK14 (p38a) | MAPK | CMGC | 3fln | C | 6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2h-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 5090 | 1.00 | |||
| MAPK14 (p38a) | MAPK | CMGC | 3fmn | A | B | 6-(2,4-difluorophenoxy)-n-(tetrahydro-2h-pyran-4-yl)-1h-pyrazolo[3,4-d]pyrimidin-3-amine | Human | 4995 | 0.49 | ||
| MAPK14 (p38a) | MAPK | CMGC | 3fmh | A | 6-(2,4-difluorophenoxy)-8-methyl-2-{[(1r)-1-methyl-2-(2h-tetrazol-2-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 5024 | 0.60 | |||
| MAPK14 (p38a) | MAPK | CMGC | 3flw | A | 6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxyethyl)propyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 5153 | 0.62 | |||
| MAPK14 (p38a) | MAPK | CMGC | 3fmk | A | 6-(2,4-difluorophenoxy)-8-methyl-2-{[(1s)-1-methyl-2-(2h-tetrazol-2-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 5209 | 0.60 | |||
| MAPK14 (p38a) | MAPK | CMGC | 3fls | A | 6-(2,4-difluorophenoxy)-8-methyl-2-{[(1r)-1-methyl-2-(methylsulfonyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 5119 | 0.60 | |||
| MAPK14 (p38a) | MAPK | CMGC | 3flz | A | 8-methyl-6-phenoxy-2-(tetrahydro-2h-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 5204 | 0.75 | |||
| MAPK14 (p38a) | MAPK | CMGC | 3flq | A | 6-(2,4-difluorophenoxy)-8-methyl-2-{[(1s)-1-methyl-2-(methylsulfonyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 5168 | 0.60 | |||
| MAPK14 (p38a) | MAPK | CMGC | 3fkl | A | n-cyclopropyl-4-methyl-3-[8-methyl-7-oxo-2-(tetrahydro-2h-pyran-4-ylamino)-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl]benzamide | Human | 5172 | 0.52 |
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