Searching for structures with analogs of -.

Search results (12 entries covering 11 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
BTKTecTK3pj2A2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-6-(4-fluorophenoxy)-8-methylpyrido[2,3-d]pyrimidin-7(8h)-oneHuman29110.44
MAPK14 (p38a)MAPKCMGC3flqA6-(2,4-difluorophenoxy)-8-methyl-2-{[(1s)-1-methyl-2-(methylsulfonyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-oneHuman51680.60
MAPK14 (p38a)MAPKCMGC3fmkA6-(2,4-difluorophenoxy)-8-methyl-2-{[(1s)-1-methyl-2-(2h-tetrazol-2-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-oneHuman52090.60
MAPK14 (p38a)MAPKCMGC3flyA6-(2,4-difluorophenoxy)-8-methyl-2-[(1-methylethyl)amino]pyrido[2,3-d]pyrimidin-7(8h)-oneHuman51130.68
MAPK14 (p38a)MAPKCMGC3fmnAA6-(2,4-difluorophenoxy)-n-(tetrahydro-2h-pyran-4-yl)-1h-pyrazolo[3,4-d]pyrimidin-3-amineHuman51960.49
MAPK14 (p38a)MAPKCMGC3flzA8-methyl-6-phenoxy-2-(tetrahydro-2h-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8h)-oneHuman52040.75
MAPK14 (p38a)MAPKCMGC3flsA6-(2,4-difluorophenoxy)-8-methyl-2-{[(1r)-1-methyl-2-(methylsulfonyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-oneHuman51190.60
MAPK14 (p38a)MAPKCMGC3flnC6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2h-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8h)-oneHuman50901.00
MAPK14 (p38a)MAPKCMGC3fmnAB6-(2,4-difluorophenoxy)-n-(tetrahydro-2h-pyran-4-yl)-1h-pyrazolo[3,4-d]pyrimidin-3-amineHuman49950.49
MAPK14 (p38a)MAPKCMGC3fmhA6-(2,4-difluorophenoxy)-8-methyl-2-{[(1r)-1-methyl-2-(2h-tetrazol-2-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-oneHuman50240.60
MAPK14 (p38a)MAPKCMGC3flwA6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxyethyl)propyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-oneHuman51530.62
MAPK14 (p38a)MAPKCMGC3fklAn-cyclopropyl-4-methyl-3-[8-methyl-7-oxo-2-(tetrahydro-2h-pyran-4-ylamino)-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl]benzamideHuman51720.52