Searching for structures with analogs of Darovasertib.
Search results (4 entries covering 2 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| PRKCA (PKCa) | PKC | AGC | 8u37 | A | A | (6m)-3-amino-n-{4-[(3r,4s)-4-amino-3-methoxypiperidin-1-yl]pyridin-3-yl}-6-[3-(trifluoromethoxy)pyridin-2-yl]pyrazine-2-carboxamide | Human | 15159 | 0.49 | ||
| PRKCA (PKCa) | PKC | AGC | 8uak | A | A | (6m)-3-amino-n-[3-(4-amino-4-methylpiperidin-1-yl)pyridin-2-yl]-6-[3-(trifluoromethyl)pyridin-2-yl]pyrazine-2-carboxamide | Human | 15161 | 1.00 | ||
| PRKCA (PKCa) | PKC | AGC | 8u37 | A | B | (6m)-3-amino-n-{4-[(3r,4s)-4-amino-3-methoxypiperidin-1-yl]pyridin-3-yl}-6-[3-(trifluoromethoxy)pyridin-2-yl]pyrazine-2-carboxamide | Human | 15162 | 0.49 | ||
| PRKCA (PKCa) | PKC | AGC | 8uak | A | B | (6m)-3-amino-n-[3-(4-amino-4-methylpiperidin-1-yl)pyridin-2-yl]-6-[3-(trifluoromethyl)pyridin-2-yl]pyrazine-2-carboxamide | Human | 15160 | 1.00 |
Darovasertib
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