| EPHA2 (EphA2) | Eph | TK | 5nk8 | A | B | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-[(2,2,6,6-tetramethyl-1-oxidanyl-piperidin-4-yl)carbamoyl]phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8088 | 0.50 | |
| EPHA2 (EphA2) | Eph | TK | 5nkd | A | B | 2-[(3~{r})-1-[3-[[5-[(2-chloranyl-6-methyl-phenyl)carbamoyl]-1,3-thiazol-2-yl]amino]phenyl]carbonylpyrrolidin-3-yl]ethanoic acid | Human | 8082 | 0.54 | |
| EPHA2 (EphA2) | Eph | TK | 5nkd | A | A | 2-[(3~{r})-1-[3-[[5-[(2-chloranyl-6-methyl-phenyl)carbamoyl]-1,3-thiazol-2-yl]amino]phenyl]carbonylpyrrolidin-3-yl]ethanoic acid | Human | 8058 | 0.54 | |
| EPHA2 (EphA2) | Eph | TK | 5nkb | A | A | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[(3,5-dimorpholin-4-ylphenyl)amino]-1,3-thiazole-5-carboxamide | Human | 8098 | 0.56 | |
| EPHA2 (EphA2) | Eph | TK | 5nkb | A | B | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[(3,5-dimorpholin-4-ylphenyl)amino]-1,3-thiazole-5-carboxamide | Human | 8097 | 0.56 | |
| EPHA2 (EphA2) | Eph | TK | 5nki | A | B | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[(3-methylsulfonyl-5-morpholin-4-yl-phenyl)amino]-1,3-thiazole-5-carboxamide | Human | 8069 | 0.53 | |
| EPHA2 (EphA2) | Eph | TK | 5nkc | A | A | (3~{s})-1-[3-[[5-[(2-chloranyl-6-methyl-phenyl)carbamoyl]-1,3-thiazol-2-yl]amino]phenyl]carbonylpyrrolidine-3-carboxylic acid | Human | 8099 | 0.54 | |
| EPHA2 (EphA2) | Eph | TK | 5nk5 | A | B | 2-[[3-[(3-aminophenyl)carbamoyl]phenyl]amino]-~{n}-(2-chloranyl-6-methyl-phenyl)-1,3-thiazole-5-carboxamide | Human | 8066 | 0.49 | |
| EPHA2 (EphA2) | Eph | TK | 5nk3 | A | B | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-[[(3~{s})-pyrrolidin-3-yl]carbamoyl]phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8080 | 0.49 | |
| EPHA2 (EphA2) | Eph | TK | 5nk7 | A | A | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-[[(3~{r},4~{r})-3-fluoranylpiperidin-4-yl]carbamoyl]phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8089 | 0.45 | |
| EPHA2 (EphA2) | Eph | TK | 5nk1 | A | B | 2-[[3-[(4-azanyl-6-methyl-1,3,5-triazin-2-yl)carbamoyl]phenyl]amino]-~{n}-(2-chloranyl-6-methyl-phenyl)-1,3-thiazole-5-carboxamide | Human | 8059 | 0.57 | |
| EPHA2 (EphA2) | Eph | TK | 5nkh | A | B | 2-[[3-(2-aminophenyl)-5-(piperidin-4-ylcarbamoyl)phenyl]amino]-~{n}-(2-chloranyl-6-methyl-phenyl)-1,3-thiazole-5-carboxamide | Human | 8077 | 0.44 | |
| EPHA2 (EphA2) | Eph | TK | 5nkh | A | A | 2-[[3-(2-aminophenyl)-5-(piperidin-4-ylcarbamoyl)phenyl]amino]-~{n}-(2-chloranyl-6-methyl-phenyl)-1,3-thiazole-5-carboxamide | Human | 8074 | 0.44 | |
| EPHA2 (EphA2) | Eph | TK | 5nk1 | A | A | 2-[[3-[(4-azanyl-6-methyl-1,3,5-triazin-2-yl)carbamoyl]phenyl]amino]-~{n}-(2-chloranyl-6-methyl-phenyl)-1,3-thiazole-5-carboxamide | Human | 8064 | 0.57 | |
| EPHA2 (EphA2) | Eph | TK | 5nk5 | A | A | 2-[[3-[(3-aminophenyl)carbamoyl]phenyl]amino]-~{n}-(2-chloranyl-6-methyl-phenyl)-1,3-thiazole-5-carboxamide | Human | 8068 | 0.49 | |
| EPHA2 (EphA2) | Eph | TK | 5nkc | A | B | (3~{s})-1-[3-[[5-[(2-chloranyl-6-methyl-phenyl)carbamoyl]-1,3-thiazol-2-yl]amino]phenyl]carbonylpyrrolidine-3-carboxylic acid | Human | 8072 | 0.54 | |
| EPHA2 (EphA2) | Eph | TK | 5i9y | A | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7194 | 1.00 | |
| EPHA2 (EphA2) | Eph | TK | 5nk0 | A | A | 2-[[3-[(3-azanyl-2,2-dimethyl-propyl)carbamoyl]phenyl]amino]-~{n}-(2-chloranyl-6-methyl-phenyl)-1,3-thiazole-5-carboxamide | Human | 8095 | 0.51 | |
| EPHA2 (EphA2) | Eph | TK | 5nk6 | A | A | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-[(4-oxidanylcyclohexyl)carbamoyl]phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8094 | 0.48 | |
| EPHA2 (EphA2) | Eph | TK | 5nkf | A | B | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-(piperidin-4-ylcarbamoyl)-5-(trifluoromethyl)phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8071 | 0.45 | |
| EPHA2 (EphA2) | Eph | TK | 5nka | A | B | 4-[[3-[[5-[(2-chloranyl-6-methyl-phenyl)carbamoyl]-1,3-thiazol-2-yl]amino]phenyl]carbonylamino]cyclohexane-1-carboxylic acid | Human | 8086 | 0.49 | |
| EPHA2 (EphA2) | Eph | TK | 5nk6 | A | B | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-[(4-oxidanylcyclohexyl)carbamoyl]phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8061 | 0.48 | |
| EPHA2 (EphA2) | Eph | TK | 5nk8 | A | A | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-[(2,2,6,6-tetramethyl-1-oxidanyl-piperidin-4-yl)carbamoyl]phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8062 | 0.50 | |
| EPHA2 (EphA2) | Eph | TK | 5nk4 | A | B | 2-[[3-[[(4~{r})-3,3-bis(fluoranyl)piperidin-4-yl]carbamoyl]phenyl]amino]-~{n}-(2-chloranyl-6-methyl-phenyl)-1,3-thiazole-5-carboxamide | Human | 8076 | 0.48 | |
| EPHA2 (EphA2) | Eph | TK | 5njz | A | A | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-(piperidin-4-ylcarbamoyl)phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8093 | 0.48 | |
| EPHA2 (EphA2) | Eph | TK | 5nkg | A | B | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-ethyl-5-(piperidin-4-ylcarbamoyl)phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8090 | 0.46 | |
| EPHA2 (EphA2) | Eph | TK | 5nki | A | A | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[(3-methylsulfonyl-5-morpholin-4-yl-phenyl)amino]-1,3-thiazole-5-carboxamide | Human | 8084 | 0.53 | |
| EPHA2 (EphA2) | Eph | TK | 5nkf | A | A | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-(piperidin-4-ylcarbamoyl)-5-(trifluoromethyl)phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8087 | 0.45 | |
| EPHA2 (EphA2) | Eph | TK | 5nke | A | B | 2-[[3-bromanyl-5-(piperidin-4-ylcarbamoyl)phenyl]amino]-~{n}-(2-chloranyl-6-methyl-phenyl)-1,3-thiazole-5-carboxamide | Human | 8063 | 0.45 | |
| EPHA2 (EphA2) | Eph | TK | 5nk2 | A | A | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-[[(3~{r},4~{r})-3-fluoranylpiperidin-4-yl]carbamoyl]phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8100 | 0.45 | |
| EPHA2 (EphA2) | Eph | TK | 5nke | A | A | 2-[[3-bromanyl-5-(piperidin-4-ylcarbamoyl)phenyl]amino]-~{n}-(2-chloranyl-6-methyl-phenyl)-1,3-thiazole-5-carboxamide | Human | 8078 | 0.45 | |
| EPHA2 (EphA2) | Eph | TK | 5nka | A | A | 4-[[3-[[5-[(2-chloranyl-6-methyl-phenyl)carbamoyl]-1,3-thiazol-2-yl]amino]phenyl]carbonylamino]cyclohexane-1-carboxylic acid | Human | 8075 | 0.49 | |
| EPHA2 (EphA2) | Eph | TK | 5nk3 | A | A | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-[[(3~{s})-pyrrolidin-3-yl]carbamoyl]phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8092 | 0.49 | |
| EPHA2 (EphA2) | Eph | TK | 5nk2 | A | C | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-[[(3~{r},4~{r})-3-fluoranylpiperidin-4-yl]carbamoyl]phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8065 | 0.45 | |
| SRC | Src | TK | 6e6e | E | A | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11479 | 0.40 | |
| EPHA2 (EphA2) | Eph | TK | 5nk7 | A | B | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-[[(3~{r},4~{r})-3-fluoranylpiperidin-4-yl]carbamoyl]phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8081 | 0.45 | |
| EPHA2 (EphA2) | Eph | TK | 5njz | A | B | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-(piperidin-4-ylcarbamoyl)phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8085 | 0.48 | |
| EPHA2 (EphA2) | Eph | TK | 5nk0 | A | B | 2-[[3-[(3-azanyl-2,2-dimethyl-propyl)carbamoyl]phenyl]amino]-~{n}-(2-chloranyl-6-methyl-phenyl)-1,3-thiazole-5-carboxamide | Human | 8096 | 0.51 | |
| EPHA2 (EphA2) | Eph | TK | 5nk4 | A | A | 2-[[3-[[(4~{r})-3,3-bis(fluoranyl)piperidin-4-yl]carbamoyl]phenyl]amino]-~{n}-(2-chloranyl-6-methyl-phenyl)-1,3-thiazole-5-carboxamide | Human | 8070 | 0.48 | |
| SRC | Src | TK | 6e6e | G | A | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11493 | 0.40 | |
| SRC | Src | TK | 6e6e | A | B | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11482 | 0.40 | |
| STK10 (LOK) | STE20 | STE | 5owr | A | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 8384 | 1.00 | |
| ABL1 | Abl | TK | 4xey | B | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 1100 | 1.00 | |
| ABL1 | Abl | TK | 2gqg | A | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 1060 | 1.00 | |
| ABL1 | Abl | TK | 2gqg | A | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 1053 | 1.00 | |
| BTK | Tec | TK | 3k54 | A | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 2932 | 1.00 | |
| Epha4 (EphA4) | Eph | TK | 2y6o | A | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Mouse | 5814 | 1.00 | |
| DDR1 | DDR | TK | 6bsd | A | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 10761 | 1.00 | |
| DDR1 | DDR | TK | 5bvw | A | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 3254 | 1.00 | |
| STK24 (MST3) | STE20 | STE | 4qms | A | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 5608 | 1.00 | |
| STK24 (MST3) | STE20 | STE | 4qms | A | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 5590 | 1.00 | |
| TNK2 (ACK) | Ack | TK | 3eqp | B | | n-(2,6-dimethylphenyl)-4-(2-ethoxyphenoxy)-2-({4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl}amino)pyrimidine-5-carboxamide | Human | 3402 | 0.41 | |
| TNK2 (ACK) | Ack | TK | 3eqp | A | | n-(2,6-dimethylphenyl)-4-(2-ethoxyphenoxy)-2-({4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl}amino)pyrimidine-5-carboxamide | Human | 3403 | 0.41 | |
| EPHA2 (EphA2) | Eph | TK | 5nkg | A | A | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-ethyl-5-(piperidin-4-ylcarbamoyl)phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8079 | 0.46 | |
| MAPK14 (p38a) | MAPK | CMGC | 3lfa | A | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 5018 | 1.00 | |
| Btk (BTK) | Tec | TK | 8s9f | A | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Mouse | 14998 | 1.00 | |
| EPHA2 (EphA2) | Eph | TK | 5i9y | A | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7176 | 1.00 | |
| BTK | Tec | TK | 3oct | A | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 2899 | 1.00 | |
| BMX | Tec | TK | 3sxr | B | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 3481 | 1.00 | |
| EPHB4 (EphB4) | Eph | TK | 6fnm | A | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 10339 | 1.00 | |
| EPHB4 (EphB4) | Eph | TK | 6fnm | A | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 10342 | 1.00 | |
| Abl2 (ABL2) | Abl | TK | 4xli | B | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Mouse | 5690 | 1.00 | |
| Abl2 (ABL2) | Abl | TK | 4xli | A | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Mouse | 5689 | 1.00 | |
| SRC | Src | TK | 6e6e | F | C | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11486 | 0.40 | |
| KIT | PDGFR | TK | 6kla | A | B | n-[6-(4-ethylpiperazin-1-yl)-2-methyl-pyrimidin-4-yl]-5-pyridin-4-yl-1,3-thiazol-2-amine | Human | 11823 | 0.48 | |
| ABL1 | Abl | TK | 4xey | A | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 1094 | 1.00 | |
| ABL1 | Abl | TK | 4yc8 | A | | 2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-n-(4-phenoxyphenyl)-1,3-thiazole-5-carboxamide | Human | 6419 | 0.70 | |
| PKMYT1 (MYT1) | WEE | Other | 5vcv | A | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 8339 | 1.00 | |
| SRC | Src | TK | 6e6e | A | A | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11485 | 0.40 | |
| SRC | Src | TK | 6e6e | H | C | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11481 | 0.40 | |
| SRC | Src | TK | 6e6e | A | C | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11491 | 0.40 | |
| SRC | Src | TK | 6e6e | C | B | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11492 | 0.40 | |
| SRC | Src | TK | 6e6e | E | B | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11490 | 0.40 | |
| SRC | Src | TK | 6e6e | D | B | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11494 | 0.40 | |
| ABL1 | Abl | TK | 4yc8 | B | | 2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-n-(4-phenoxyphenyl)-1,3-thiazole-5-carboxamide | Human | 6420 | 0.70 | |
| ABL1 | Abl | TK | 2gqg | B | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 1084 | 1.00 | |
| SRC | Src | TK | 6e6e | F | A | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11487 | 0.40 | |
| SRC | Src | TK | 6e6e | F | B | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11472 | 0.40 | |
| SRC | Src | TK | 6e6e | D | A | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11489 | 0.40 | |
| SRC | Src | TK | 6e6e | B | C | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11484 | 0.40 | |
| SRC | Src | TK | 6e6e | B | A | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11480 | 0.40 | |
| SRC | Src | TK | 6e6e | G | B | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11474 | 0.40 | |
| SRC | Src | TK | 6e6e | C | A | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11471 | 0.40 | |
| SRC | Src | TK | 6e6e | D | C | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11473 | 0.40 | |
| SRC | Src | TK | 6e6e | H | A | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11475 | 0.40 | |
| SRC | Src | TK | 6e6e | E | C | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11478 | 0.40 | |
| SRC | Src | TK | 6e6e | B | B | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11476 | 0.40 | |
| ABL1 | Abl | TK | 2gqg | B | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 1082 | 1.00 | |
| PTK6 (BRK) | Src | TK | 5h2u | B | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7337 | 1.00 | |
| PTK6 (BRK) | Src | TK | 5h2u | D | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7344 | 1.00 | |
| PTK6 (BRK) | Src | TK | 5h2u | D | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7340 | 1.00 | |
| PTK6 (BRK) | Src | TK | 5h2u | C | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7342 | 1.00 | |
| PTK6 (BRK) | Src | TK | 5h2u | C | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7341 | 1.00 | |
| PTK6 (BRK) | Src | TK | 5h2u | B | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7339 | 1.00 | |
| PTK6 (BRK) | Src | TK | 5h2u | A | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7338 | 1.00 | |
| KIT | PDGFR | TK | 6kla | A | A | n-[6-(4-ethylpiperazin-1-yl)-2-methyl-pyrimidin-4-yl]-5-pyridin-4-yl-1,3-thiazol-2-amine | Human | 11825 | 0.48 | |
| SRC | Src | TK | 6e6e | H | B | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11483 | 0.40 | |
| ABL1 | Abl | TK | 7n9g | A | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 14197 | 1.00 | |
| SRC | Src | TK | 6e6e | C | C | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11488 | 0.40 | |
| SRC | Src | TK | 6e6e | G | C | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11477 | 0.40 | |
| STK10 (LOK) | STE20 | STE | 5owr | A | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 8388 | 1.00 | |
| PTK6 (BRK) | Src | TK | 5h2u | A | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7343 | 1.00 | |
| BTK | Tec | TK | 3oct | A | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 2908 | 1.00 | |
| BTK | Tec | TK | 3k54 | A | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 2906 | 1.00 | |
| BMX | Tec | TK | 3sxr | A | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 3482 | 1.00 | |
| Lyn (LYN) | Src | TK | 2zva | A | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Mouse | 5774 | 1.00 | |
| Epha4 (EphA4) | Eph | TK | 2y6o | A | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Mouse | 5811 | 1.00 | |
Match: