Searching for structures with analogs of Lirafugratinib.
Search results (4 entries covering 3 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| FGFR2 | FGFR | TK | 8u1f | A | n-[4-(4-amino-7-methyl-5-{4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7h-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-2-methylpropanamide | Human | 15202 | 0.64 | |||
| FGFR2 | FGFR | TK | 8swe | A | A | n-{4-[4-amino-5-(4-methoxyphenyl)-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}prop-2-enamide | Human | 15200 | 0.49 | ||
| FGFR2 | FGFR | TK | 8stg | A | n-{4-[(5p)-4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}-2-methylprop-2-enamide | Human | 14762 | 1.00 | |||
| FGFR2 | FGFR | TK | 8swe | A | B | n-{4-[4-amino-5-(4-methoxyphenyl)-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}prop-2-enamide | Human | 15201 | 0.49 |
Lirafugratinib
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