KLIFS - the structural kinase database

Searching for structures with analogs of Tinlorafenib.

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
BRAF	RAF	TKL	4pp7	B		n-{2,4-difluoro-3-[methyl(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}propane-1-sulfonamide	Human	3126	0.46
BRAF	RAF	TKL	4pp7	A		n-{2,4-difluoro-3-[methyl(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}propane-1-sulfonamide	Human	3094	0.46
BRAF	RAF	TKL	7k0v	A	A	n-(3,3-dimethylbutyl)-n'-{2-fluoro-5-[(5-fluoro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-methylphenyl}urea	Human	13617	0.40
BRAF	RAF	TKL	7k0v	A	B	n-(3,3-dimethylbutyl)-n'-{2-fluoro-5-[(5-fluoro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-methylphenyl}urea	Human	13616	0.40