| CDK2 | CDK | CMGC | 4bcp | C | A | 2-[[3-(1,4-diazepan-1-yl)phenyl]amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile | Human | 3872 | 0.47 | |
| CDK2 | CDK | CMGC | 4bcn | A | B | 2-[(3-hydroxyphenyl)amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile | Human | 4298 | 0.56 | |
| CDK2 | CDK | CMGC | 4bcn | C | A | 2-[(3-hydroxyphenyl)amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile | Human | 4436 | 0.56 | |
| CDK2 | CDK | CMGC | 4bcp | A | B | 2-[[3-(1,4-diazepan-1-yl)phenyl]amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile | Human | 4304 | 0.47 | |
| CDK2 | CDK | CMGC | 1pxn | A | A | 4-[4-(4-methyl-2-methylamino-thiazol-5-yl)-pyrimidin-2-ylamino]-phenol | Human | 4383 | 0.41 | |
| CDK2 | CDK | CMGC | 4bck | A | B | 3-[[5-cyano-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide | Human | 3960 | 0.77 | |
| CDK2 | CDK | CMGC | 4bck | C | B | 3-[[5-cyano-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide | Human | 4506 | 0.77 | |
| CDK2 | CDK | CMGC | 4bco | A | B | 2-[[3-(4-ethanoyl-1,4-diazepan-1-yl)phenyl]amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile | Human | 4051 | 0.47 | |
| CDK2 | CDK | CMGC | 4bck | C | D | 3-[[5-cyano-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide | Human | 4080 | 0.77 | |
| CDK2 | CDK | CMGC | 4bco | C | B | 2-[[3-(4-ethanoyl-1,4-diazepan-1-yl)phenyl]amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile | Human | 4018 | 0.47 | |
| CDK2 | CDK | CMGC | 4bck | C | C | 3-[[5-cyano-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide | Human | 4029 | 0.77 | |
| CDK2 | CDK | CMGC | 4bcq | A | B | 4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]-2-{[3-(morpholin-4-ylcarbonyl)phenyl]amino}pyrimidine-5-carbonitrile | Human | 4415 | 0.50 | |
| CDK9 | CDK | CMGC | 4bci | A | | 3-[[5-cyano-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide | Human | 2243 | 0.77 | |
| CDK2 | CDK | CMGC | 4bcn | A | A | 2-[(3-hydroxyphenyl)amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile | Human | 4084 | 0.56 | |
| CDK2 | CDK | CMGC | 4bcq | C | B | 4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]-2-{[3-(morpholin-4-ylcarbonyl)phenyl]amino}pyrimidine-5-carbonitrile | Human | 4120 | 0.50 | |
| CDK2 | CDK | CMGC | 4bcq | A | A | 4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]-2-{[3-(morpholin-4-ylcarbonyl)phenyl]amino}pyrimidine-5-carbonitrile | Human | 4396 | 0.50 | |
| CDK2 | CDK | CMGC | 4bco | C | A | 2-[[3-(4-ethanoyl-1,4-diazepan-1-yl)phenyl]amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile | Human | 4333 | 0.47 | |
| ITK | Tec | TK | 3qgw | A | B | 3-[(8-phenylthieno[2,3-h]quinazolin-2-yl)amino]benzenesulfonamide | Human | 57 | 0.43 | |
| ITK | Tec | TK | 3qgw | A | A | 3-[(8-phenylthieno[2,3-h]quinazolin-2-yl)amino]benzenesulfonamide | Human | 11 | 0.43 | |
| CDK2 | CDK | CMGC | 4bco | A | A | 2-[[3-(4-ethanoyl-1,4-diazepan-1-yl)phenyl]amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile | Human | 3988 | 0.47 | |
| CDK2 | CDK | CMGC | 4bcp | C | B | 2-[[3-(1,4-diazepan-1-yl)phenyl]amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile | Human | 4501 | 0.47 | |
| CDK2 | CDK | CMGC | 4bck | A | C | 3-[[5-cyano-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide | Human | 4433 | 0.77 | |
| CDK2 | CDK | CMGC | 4bck | A | A | 3-[[5-cyano-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide | Human | 4095 | 0.77 | |
| CDK2 | CDK | CMGC | 4bcq | C | A | 4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]-2-{[3-(morpholin-4-ylcarbonyl)phenyl]amino}pyrimidine-5-carbonitrile | Human | 3996 | 0.50 | |
| CDK2 | CDK | CMGC | 4bck | C | A | 3-[[5-cyano-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide | Human | 4268 | 0.77 | |
| CDK2 | CDK | CMGC | 4bcp | A | A | 2-[[3-(1,4-diazepan-1-yl)phenyl]amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile | Human | 4552 | 0.47 | |
| CDK2 | CDK | CMGC | 4bcn | C | B | 2-[(3-hydroxyphenyl)amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile | Human | 4150 | 0.56 | |
| CDK2 | CDK | CMGC | 4bck | A | D | 3-[[5-cyano-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide | Human | 4563 | 0.77 | |
| CDK9 | CDK | CMGC | 4bcg | A | | 2-[[3-(1,4-diazepan-1-yl)phenyl]amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile | Human | 2255 | 0.47 | |
| CDK9 | CDK | CMGC | 4bcj | A | | 2-[(3-hydroxyphenyl)amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile | Human | 2247 | 0.56 | |
| CDK9 | CDK | CMGC | 4bcf | A | | 2-[[3-(4-ethanoyl-1,4-diazepan-1-yl)phenyl]amino]-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidine-5-carbonitrile | Human | 2257 | 0.47 | |
| ITK | Tec | TK | 3qgy | A | A | 3-[(8-phenylthieno[2,3-h]quinazolin-2-yl)amino]benzenesulfonamide | Human | 35 | 0.43 | |
| ITK | Tec | TK | 3qgy | A | B | 3-[(8-phenylthieno[2,3-h]quinazolin-2-yl)amino]benzenesulfonamide | Human | 72 | 0.43 | |
Match: