Searching for structures with analogs of Ebvaciclib.

Search results (9 entries covering 7 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
CDK2CDKCMGC7kjsA6-(difluoromethyl)-8-[(1r,2r)-2-hydroxy-2-methylcyclopentyl]-2-{[1-(methylsulfonyl)piperidin-4-yl]amino}pyrido[2,3-d]pyrimidin-7(8h)-oneHuman137401.00
CDK2CDKCMGC8erdAA(2-{[1-(methanesulfonyl)piperidin-4-yl]amino}quinazolin-7-yl)[(2s)-2-methylpyrrolidin-1-yl]methanoneHuman149490.49
CDK2CDKCMGC8erdAB(2-{[1-(methanesulfonyl)piperidin-4-yl]amino}quinazolin-7-yl)[(2s)-2-methylpyrrolidin-1-yl]methanoneHuman149510.49
CDK6CDKCMGC8i0mA2-[(4-azanylcyclohexyl)amino]-7-cyclopentyl-~{n},~{n}-dimethyl-pyrrolo[2,3-d]pyrimidine-6-carboxamideHuman151640.40
CDK2CDKCMGC2fvdA(4-amino-2-{[1-(methylsulfonyl)piperidin-4-yl]amino}pyrimidin-5-yl)(2,3-difluoro-6-methoxyphenyl)methanoneHuman44080.42
MAPK10 (JNK3)MAPKCMGC4y46A1-{trans-4-[(8-cyclopentyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]cyclohexyl}-3-propan-2-ylureaHuman34140.42
CDK2CDKCMGC2wxvCn,1-dimethyl-8-{[1-(methylsulfonyl)piperidin-4-yl]amino}-1h-pyrazolo[4,3-h]quinazoline-3-carboxamideHuman45040.42
CDK2CDKCMGC2wxvAn,1-dimethyl-8-{[1-(methylsulfonyl)piperidin-4-yl]amino}-1h-pyrazolo[4,3-h]quinazoline-3-carboxamideHuman43180.42
CDK9CDKCMGC8i0lA2-[(4-azanylcyclohexyl)amino]-7-cyclopentyl-~{n},~{n}-dimethyl-pyrrolo[2,3-d]pyrimidine-6-carboxamideHuman151700.40