Searching for structures with analogs of Erlotinib.

Search results (29 entries covering 18 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
EGFREGFRTK2ityAgefitinibHuman7900.42
EGFREGFRTK2itzAgefitinibHuman7890.42
TTBK1TTBKCK14btkA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman7710.55
EGFREGFRTK3ug2ABgefitinibHuman8190.42
EGFREGFRTK4i22AgefitinibHuman8230.42
EGFREGFRTK4wkqABgefitinibHuman8370.42
EGFREGFRTK1m17AA[6,7-bis(2-methoxy-ethoxy)quinazoline-4-yl]-(3-ethynylphenyl)amineHuman8731.00
EGFREGFRTK4wkqAAgefitinibHuman8890.42
EGFREGFRTK3ug2AAgefitinibHuman8980.42
EGFREGFRTK1m17AB[6,7-bis(2-methoxy-ethoxy)quinazoline-4-yl]-(3-ethynylphenyl)amineHuman9051.00
AURKA (AurA)AurOther2c6eBn-{5-[(7-{[(2s)-2-hydroxy-3-piperidin-1-ylpropyl]oxy}-6-methoxyquinazolin-4-yl)amino]pyrimidin-2-yl}benzamideHuman20460.41
CSNK2A1 (CK2a1)CK2CMGC3pe2AA5-[(3-ethynylphenyl)amino]pyrimido[4,5-c]quinoline-8-carboxylic acidHuman55080.43
CSNK2A1 (CK2a1)CK2CMGC3pe2AB5-[(3-ethynylphenyl)amino]pyrimido[4,5-c]quinoline-8-carboxylic acidHuman55190.43
AURKA (AurA)AurOther2c6eAn-{5-[(7-{[(2s)-2-hydroxy-3-piperidin-1-ylpropyl]oxy}-6-methoxyquinazolin-4-yl)amino]pyrimidin-2-yl}benzamideHuman19890.41
RETRetTK5amnA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman64120.55
EGFREGFRTK4hjoA[6,7-bis(2-methoxy-ethoxy)quinazoline-4-yl]-(3-ethynylphenyl)amineHuman8351.00
EGFREGFRTK2itoAgefitinibHuman7830.42
CDK2CDKCMGC1di8A4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman45770.55
GAKNAKOther5y7zAgefitinibHuman103320.42
GAKNAKOther5y7zBgefitinibHuman103310.42
GAKNAKOther5y80ABgefitinibHuman103300.42
GAKNAKOther5y80AAgefitinibHuman103290.42
RIPK2RIPKTKL6rn8A2-[4-(1,3-benzothiazol-5-ylamino)-6-~{tert}-butylsulfonyl-quinazolin-7-yl]oxyethyl dihydrogen phosphateHuman114340.40
RIPK2RIPKTKL6rn8B2-[4-(1,3-benzothiazol-5-ylamino)-6-~{tert}-butylsulfonyl-quinazolin-7-yl]oxyethyl dihydrogen phosphateHuman114310.40
TTBK2TTBKCK16u0kAA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120460.55
TTBK2TTBKCK16u0kBB4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120470.55
TTBK2TTBKCK16u0kAB4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120480.55
TTBK2TTBKCK16u0kBA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120490.55
MAPK14 (p38a)MAPKCMGC1di9A4-[3-methylsulfanylanilino]-6,7-dimethoxyquinazolineHuman52510.51