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Searching for structures with analogs of
Entospletinib
.
Search results (15 entries covering 9 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
Similarity (MFP)
File
BTK
Tec
TK
4ot5
A
4-tert-butyl-n-{3-[8-({4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}amino)imidazo[1,2-a]pyrazin-6-yl]phenyl}benzamide
Human
2913
0.41
AURKA (AurA)
Aur
Other
2xne
A
3-chloro-n-(4-morpholin-4-ylphenyl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine
Human
7221
0.47
SYK
Syk
TK
4puz
B
6-(1h-indazol-6-yl)-n-[4-(morpholin-4-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine
Human
1153
1.00
AURKA (AurA)
Aur
Other
2xng
A
B
n-(3-{3-chloro-8-[(4-morpholin-4-ylphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzyl)methanesulfonamide
Human
2083
0.45
AURKA (AurA)
Aur
Other
2xng
A
A
n-(3-{3-chloro-8-[(4-morpholin-4-ylphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzyl)methanesulfonamide
Human
1994
0.45
JAK2
JakA
TK
4bbe
D
n-[4-[2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl]phenyl]ethanamide
Human
3726
0.42
JAK2
JakA
TK
4bbe
C
n-[4-[2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl]phenyl]ethanamide
Human
3649
0.42
JAK2
JakA
TK
4bbe
A
n-[4-[2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl]phenyl]ethanamide
Human
3670
0.42
JAK2
JakA
TK
4bbe
B
n-[4-[2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl]phenyl]ethanamide
Human
3727
0.42
SYK
Syk
TK
6vov
A
6-(6-aminopyrazin-2-yl)-n-{4-[4-(oxetan-3-yl)piperazin-1-yl]phenyl}imidazo[1,2-a]pyrazin-8-amine
Human
12041
0.49
SYK
Syk
TK
4puz
A
6-(1h-indazol-6-yl)-n-[4-(morpholin-4-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine
Human
1163
1.00
SYK
Syk
TK
5c26
A
3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzamide
Human
6131
0.42
SYK
Syk
TK
6vov
B
6-(6-aminopyrazin-2-yl)-n-{4-[4-(oxetan-3-yl)piperazin-1-yl]phenyl}imidazo[1,2-a]pyrazin-8-amine
Human
12040
0.49
SYK
Syk
TK
4pv0
A
4-[(3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzoyl)amino]benzoic acid
Human
1161
0.40
BTK
Tec
TK
4ot6
A
4-(methylsulfonyl)-n-[3-(8-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}imidazo[1,2-a]pyrazin-6-yl)phenyl]benzamide
Human
2931
0.49
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