Searching for structures with analogs of Fasudil.

Search results (21 entries covering 11 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
ROCK1DMPKAGC3d9vA(s)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazineHuman26960.43
ROCK1DMPKAGC3d9vB(s)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazineHuman27010.43
CSNK2A1 (CK2a1)CK2CMGC8pvpA~{n}-[5-[(3-chloranyl-4-phenyl-phenyl)methylamino]pentyl]isoquinoline-5-sulfonamideHuman149770.40
CDC42BPB (MRCKb)DMPKAGC3tkuB5-(1,4-diazepan-1-sulfonyl)isoquinolineHuman48591.00
DAPK2DAPKCAMK2ckeDn-(2-aminoethyl)isoquinoline-5-sulfonamideHuman11410.48
HASPIN (Haspin)HaspinOther3fmdABn-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamideHuman38100.44
DAPK2DAPKCAMK2ckeCn-(2-aminoethyl)isoquinoline-5-sulfonamideHuman11350.48
DAPK2DAPKCAMK2ckeAn-(2-aminoethyl)isoquinoline-5-sulfonamideHuman11430.48
CDC42BPB (MRCKb)DMPKAGC3tkuA5-(1,4-diazepan-1-sulfonyl)isoquinolineHuman48621.00
PRKACA (PKACa)PKAAGC3vqhAAn-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamideHuman52710.44
PRKACA (PKACa)PKAAGC3vqhABn-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamideHuman52750.44
AKT2AktAGC2jdoAisoquinoline-5-sulfonic acid (2-(2-(4-chlorobenzyloxy)ethylamino)ethyl)amideHuman19220.44
HASPIN (Haspin)HaspinOther3fmdAAn-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamideHuman37980.44
PAK4STE20STE5vefAB5-(1,4-diazepan-1-sulfonyl)isoquinolineHuman85711.00
PAK4STE20STE5vefAA5-(1,4-diazepan-1-sulfonyl)isoquinolineHuman85691.00
ROCK1DMPKAGC2etkA1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazineHuman27070.63
ROCK1DMPKAGC2esmA5-(1,4-diazepan-1-sulfonyl)isoquinolineHuman27261.00
ROCK1DMPKAGC2etkB1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazineHuman27230.63
ROCK1DMPKAGC2esmB5-(1,4-diazepan-1-sulfonyl)isoquinolineHuman27141.00
Prkaca (PKACa)PKAAGC2erzE1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazineMouse58950.63
DAPK2DAPKCAMK2ckeBn-(2-aminoethyl)isoquinoline-5-sulfonamideHuman11320.48