Search results (12 entries covering 7 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
| CDKL1 | CDKL | CMGC | 4agu | C | n-(5-{[(2s)-4-amino-2-(3-chlorophenyl)butanoyl]amino}-1h-indazol-3-yl)benzamide | Human | 762 | |||
| CDKL5 | CDKL | CMGC | 9epu | A | ~{n}-[5-[(5-propan-2-yl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide | Human | 15440 | |||
| CDKL5 | CDKL | CMGC | 4bgq | A | A | [4-({4-[(3-cyclopentyl-1h-pyrazol-5-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrile | Human | 1425 | ||
| CDKL5 | CDKL | CMGC | 4bgq | A | B | [4-({4-[(3-cyclopentyl-1h-pyrazol-5-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrile | Human | 1426 | ||
| CDKL5 | CDKL | CMGC | 8cie | A | 4-[[3,5-bis(fluoranyl)phenyl]carbonylamino]-~{n}-piperidin-4-yl-1~{h}-pyrazole-3-carboxamide | Human | 14778 | |||
| CDKL3 | CDKL | CMGC | 3zdu | A | [4-({4-[(3-cyclopentyl-1h-pyrazol-5-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrile | Human | 4677 | |||
| CDKL1 | CDKL | CMGC | 4agu | A | n-(5-{[(2s)-4-amino-2-(3-chlorophenyl)butanoyl]amino}-1h-indazol-3-yl)benzamide | Human | 761 | |||
| CDKL1 | CDKL | CMGC | 4agu | B | n-(5-{[(2s)-4-amino-2-(3-chlorophenyl)butanoyl]amino}-1h-indazol-3-yl)benzamide | Human | 760 | |||
| CDKL2 | CDKL | CMGC | 4bbm | B | 4'-[5-[[3-[(cyclopropylamino)methyl]phenyl]amino]-1h-pyrazol-3-yl]-[1,1'-biphenyl]-2,4-diol | Human | 965 | |||
| CDKL2 | CDKL | CMGC | 4aaa | A | A | 5-amino-3-{[4-(aminosulfonyl)phenyl]amino}-n-(2,6-difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide | Human | 964 | ||
| CDKL2 | CDKL | CMGC | 4aaa | A | B | 5-amino-3-{[4-(aminosulfonyl)phenyl]amino}-n-(2,6-difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide | Human | 962 | ||
| CDKL2 | CDKL | CMGC | 4bbm | A | 4'-[5-[[3-[(cyclopropylamino)methyl]phenyl]amino]-1h-pyrazol-3-yl]-[1,1'-biphenyl]-2,4-diol | Human | 963 |