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Search results (148 entries covering 52 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetails File
ROCK2DMPKAGC6p5mAB6-(5-methyl-1h-pyrazol-4-yl)-2-[(pyrrolidin-1-yl)methyl]thieno[3,2-d]pyrimidin-4(3h)-oneHuman11915
ROCK2DMPKAGC4l6qA6-[4-(aminomethyl)-2-fluorophenoxy]-2,1-benzoxaborol-1(3h)-olHuman1811
ROCK2DMPKAGC6p5mDA-Human11925
ROCK2DMPKAGC7jovBn-[(1s)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1h-pyrazol-4-yl)benzamideHuman12765
ROCK2DMPKAGC6p5pC2-[(2s)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1h-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3h)-oneHuman11919
ROCK2DMPKAGC7jntABn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12754
ROCK2DMPKAGC5u7qB-Human7990
ROCK1DMPKAGC5uzjAn-[4-(2-aminopyridin-4-yl)-1,3-thiazol-2-yl]-2-(3-methoxyphenyl)acetamideHuman9706
ROCK1DMPKAGC5wnfAB1-(4-amino-1,2,5-oxadiazol-3-yl)-5-methyl-n-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)-1h-1,2,3-triazole-4-carboxamideHuman10444
ROCK1DMPKAGC2etrB(r)-trans-4-(1-aminoethyl)-n-(4-pyridyl) cyclohexanecarboxamideHuman2704
ROCK1DMPKAGC3d9vA(s)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazineHuman2696
ROCK1DMPKAGC5wnhB(2r)-n-(3-cyanophenyl)-2-{3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}pyrrolidine-1-carboxamideHuman10449
ROCK1DMPKAGC3nczDcis-4-amino-n-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)cyclohexanecarboxamideHuman2724
ROCK2DMPKAGC7p6pA~{n}-[(1~{r})-1-(3-methoxyphenyl)ethyl]-4-pyridin-4-yl-cyclohexane-1-carboxamideHuman15972
ROCK1DMPKAGC7s25AA2-[3-(methoxymethyl)phenyl]-n-[4-(1h-pyrazol-4-yl)phenyl]acetamideHuman14435
ROCK1DMPKAGC7s26A2-[methyl(phenyl)amino]-1-[4-(1h-pyrrolo[2,3-b]pyridin-3-yl)-3,6-dihydropyridin-1(2h)-yl]ethan-1-oneHuman14437
ROCK1DMPKAGC5wnfDA1-(4-amino-1,2,5-oxadiazol-3-yl)-5-methyl-n-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)-1h-1,2,3-triazole-4-carboxamideHuman10451
ROCK1DMPKAGC9q8rA(7~{s})-7-(2,3-dihydro-1~{h}-inden-2-yl)-2-(hydroxymethyl)-~{n}-isoquinolin-6-yl-5-methyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxamideHuman16202
ROCK2DMPKAGC6p5pA2-[(2s)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1h-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3h)-oneHuman11914
ROCK1DMPKAGC5wneC3,4-dimethoxy-n-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)benzamideHuman10462
ROCK1DMPKAGC4w7pCn~1~-[2-(1h-indazol-5-yl)pyrido[3,4-d]pyrimidin-4-yl]-2-methylpropane-1,2-diamineHuman2688
ROCK1DMPKAGC5bmlAn-[4-(2-fluoropyridin-4-yl)thiophen-2-yl]-2-{3-[(methylsulfonyl)amino]phenyl}acetamideHuman2713
ROCK1DMPKAGC4yvcA2-fluoro-n-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]benzamideHuman2715
ROCK1DMPKAGC5wneD3,4-dimethoxy-n-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)benzamideHuman10445
ROCK1DMPKAGC3ndmB(3s,4r)-n-(7-chloro-1-oxo-1,4-dihydroisoquinolin-6-yl)-4-(4-chlorophenyl)pyrrolidine-3-carboxamideHuman2698
ROCK1DMPKAGC5hvuB2-{3-[3-(piperidin-4-yl)propoxy]phenyl}-n-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]acetamideHuman7415
ROCK2DMPKAGC7p6nA~{n}-[(1~{r})-1-(3-methoxyphenyl)ethyl]-4-pyridin-4-yl-piperidine-1-carboxamideHuman14314
ROCK1DMPKAGC3nczAcis-4-amino-n-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)cyclohexanecarboxamideHuman2699
ROCK1DMPKAGC5kksB2-[3-(methylsulfonylamino)phenyl]-~{n}-[4-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)-1,3-thiazol-2-yl]ethanamideHuman8181
ROCK1DMPKAGC5kktA2-[3-[3-(4-methylpiperazin-1-yl)propoxy]phenyl]-~{n}-[4-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)-1,3-thiazol-2-yl]ethanamideHuman8182
ROCK1DMPKAGC3tv7B1-[(1r)-1-(3-methoxyphenyl)ethyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)ureaHuman2703
ROCK1DMPKAGC6e9wAn-[(2,3-dihydro-1,4-benzodioxin-5-yl)methyl]-4-(pyridin-4-yl)benzamideHuman10691
ROCK1DMPKAGC7s25AB2-[3-(methoxymethyl)phenyl]-n-[4-(1h-pyrazol-4-yl)phenyl]acetamideHuman14436
ROCK1DMPKAGC2etrA(r)-trans-4-(1-aminoethyl)-n-(4-pyridyl) cyclohexanecarboxamideHuman2700
ROCK1DMPKAGC2v55Aphosphoaminophosphonic acid-adenylate esterHuman2694
ROCK1DMPKAGC4yveA2-(3-methoxyphenyl)-n-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]acetamideHuman2693
ROCK2DMPKAGC7jntGBn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12767
DMPK (DMPK1)DMPKAGC2vd5A3-[1-(3-aminopropyl)-1h-indol-3-yl]-4-(1-methyl-1h-indol-3-yl)-1h-pyrrole-2,5-dioneHuman1901
ROCK1DMPKAGC4w7pBn~1~-[2-(1h-indazol-5-yl)pyrido[3,4-d]pyrimidin-4-yl]-2-methylpropane-1,2-diamineHuman2708
ROCK2DMPKAGC7jntCBn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12745
ROCK2DMPKAGC5u7rC(1s,4s)-4-(4-fluorophenyl)-4-hydroxy-6'-(5-methyl-1h-pyrazol-4-yl)-1'h-spiro[cyclohexane-1,2'-thieno[3,2-d]pyrimidin]-4'(3'h)-oneHuman7983
ROCK2DMPKAGC4wotAmethyl 3-[({2'-(aminomethyl)-5'-[(3-fluoropyridin-4-yl)carbamoyl]biphenyl-3-yl}carbonyl)amino]-4-fluorobenzoateHuman6827
ROCK2DMPKAGC7jntFBn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12758
ROCK2DMPKAGC6p5pD2-[(2s)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1h-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3h)-oneHuman11918
ROCK2DMPKAGC5u7qA-Human7988
ROCK1DMPKAGC5wnhC(2r)-n-(3-cyanophenyl)-2-{3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}pyrrolidine-1-carboxamideHuman10456
ROCK2DMPKAGC7jovEn-[(1s)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1h-pyrazol-4-yl)benzamideHuman12762
ROCK2DMPKAGC7jovGn-[(1s)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1h-pyrazol-4-yl)benzamideHuman12763
ROCK2DMPKAGC5u7qC-Human7987
ROCK2DMPKAGC5u7qD-Human7986
ROCK2DMPKAGC7jovDn-[(1s)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1h-pyrazol-4-yl)benzamideHuman12764
ROCK2DMPKAGC4wotBmethyl 3-[({2'-(aminomethyl)-5'-[(3-fluoropyridin-4-yl)carbamoyl]biphenyl-3-yl}carbonyl)amino]-4-fluorobenzoateHuman6829
CDC42BPB (MRCKb)DMPKAGC3tkuB5-(1,4-diazepan-1-sulfonyl)isoquinolineHuman4859
ROCK2DMPKAGC5u7rB(1s,4s)-4-(4-fluorophenyl)-4-hydroxy-6'-(5-methyl-1h-pyrazol-4-yl)-1'h-spiro[cyclohexane-1,2'-thieno[3,2-d]pyrimidin]-4'(3'h)-oneHuman7984
ROCK1DMPKAGC5wngA(2r)-n-(3-cyanophenyl)-2-(3-{[(6s)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]carbamoyl}phenyl)pyrrolidine-1-carboxamideHuman10459
ROCK1DMPKAGC5wnfBB1-(4-amino-1,2,5-oxadiazol-3-yl)-5-methyl-n-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)-1h-1,2,3-triazole-4-carboxamideHuman10450
ROCK1DMPKAGC3twjD-Human2690
ROCK1DMPKAGC4w7pAn~1~-[2-(1h-indazol-5-yl)pyrido[3,4-d]pyrimidin-4-yl]-2-methylpropane-1,2-diamineHuman2721
ROCK2DMPKAGC7jntBBn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12766
ROCK1DMPKAGC5hvuA2-{3-[3-(piperidin-4-yl)propoxy]phenyl}-n-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]acetamideHuman7414
ROCK1DMPKAGC5wnfDB1-(4-amino-1,2,5-oxadiazol-3-yl)-5-methyl-n-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)-1h-1,2,3-triazole-4-carboxamideHuman10452
ROCK1DMPKAGC5wnfBA1-(4-amino-1,2,5-oxadiazol-3-yl)-5-methyl-n-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)-1h-1,2,3-triazole-4-carboxamideHuman10463
ROCK1DMPKAGC3twjB-Human2718
ROCK1DMPKAGC5wneA3,4-dimethoxy-n-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)benzamideHuman10446
ROCK1DMPKAGC2etkA1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazineHuman2707
ROCK1DMPKAGC2esmA5-(1,4-diazepan-1-sulfonyl)isoquinolineHuman2726
ROCK1DMPKAGC5wnfCB1-(4-amino-1,2,5-oxadiazol-3-yl)-5-methyl-n-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)-1h-1,2,3-triazole-4-carboxamideHuman10460
ROCK1DMPKAGC3ndmD(3s,4r)-n-(7-chloro-1-oxo-1,4-dihydroisoquinolin-6-yl)-4-(4-chlorophenyl)pyrrolidine-3-carboxamideHuman2705
ROCK1DMPKAGC3tv7C1-[(1r)-1-(3-methoxyphenyl)ethyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)ureaHuman2717
ROCK1DMPKAGC7jouAn-[(1s)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1h-pyrazol-4-yl)benzamideHuman12768
ROCK1DMPKAGC4yvcB2-fluoro-n-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]benzamideHuman2727
ROCK1DMPKAGC3v8sC1-(1h-indazol-5-yl)-3-(2-phenylethyl)ureaHuman2702
ROCK1DMPKAGC3nczBcis-4-amino-n-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)cyclohexanecarboxamideHuman2720
ROCK1DMPKAGC5bmlBn-[4-(2-fluoropyridin-4-yl)thiophen-2-yl]-2-{3-[(methylsulfonyl)amino]phenyl}acetamideHuman2691
ROCK1DMPKAGC5kktB2-[3-[3-(4-methylpiperazin-1-yl)propoxy]phenyl]-~{n}-[4-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)-1,3-thiazol-2-yl]ethanamideHuman8184
ROCK1DMPKAGC3v8sB1-(1h-indazol-5-yl)-3-(2-phenylethyl)ureaHuman2709
ROCK1DMPKAGC3tv7D1-[(1r)-1-(3-methoxyphenyl)ethyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)ureaHuman2725
ROCK1DMPKAGC5wneB3,4-dimethoxy-n-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)benzamideHuman10453
ROCK1DMPKAGC5wnhD(2r)-n-(3-cyanophenyl)-2-{3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}pyrrolidine-1-carboxamideHuman10454
ROCK1DMPKAGC5wnfAA1-(4-amino-1,2,5-oxadiazol-3-yl)-5-methyl-n-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)-1h-1,2,3-triazole-4-carboxamideHuman10447
ROCK1DMPKAGC3twjC1-[(3-hydroxyphenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)ureaHuman2689
ROCK1DMPKAGC3ndmC(3s,4r)-n-(7-chloro-1-oxo-1,4-dihydroisoquinolin-6-yl)-4-(4-chlorophenyl)pyrrolidine-3-carboxamideHuman2722
ROCK1DMPKAGC3ndmA-Human2695
ROCK1DMPKAGC2etkB1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazineHuman2723
DMPK (DMPK1)DMPKAGC2vd5B3-[1-(3-aminopropyl)-1h-indol-3-yl]-4-(1-methyl-1h-indol-3-yl)-1h-pyrrole-2,5-dioneHuman1902
CDC42BPB (MRCKb)DMPKAGC4ualAA4-chloro-1-(piperidin-4-yl)-n-[3-(pyridin-2-yl)-1h-pyrazol-4-yl]-1h-pyrazole-3-carboxamideHuman4861
CDC42BPB (MRCKb)DMPKAGC3qfvA2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamideHuman4860
CDC42BPB (MRCKb)DMPKAGC5oteA2-[4-[(6~{s})-1,8-diazaspiro[5.5]undecan-8-yl]-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]-1,3-thiazoleHuman9578
CDC42BPB (MRCKb)DMPKAGC5otfA(6~{s})-8-(3-pyrimidin-4-yl-1~{h}-pyrrolo[2,3-b]pyridin-4-yl)-1,8-diazaspiro[5.5]undecaneHuman9577
CDC42BPB (MRCKb)DMPKAGC3tkuA5-(1,4-diazepan-1-sulfonyl)isoquinolineHuman4862
CDC42BPB (MRCKb)DMPKAGC4uakAAadenosine-5'-diphosphateHuman4864
CDC42BPB (MRCKb)DMPKAGC4ualAB4-chloro-1-(piperidin-4-yl)-n-[3-(pyridin-2-yl)-1h-pyrazol-4-yl]-1h-pyrazole-3-carboxamideHuman4858
CDC42BPB (MRCKb)DMPKAGC3qfvB2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamideHuman4857
CDC42BPB (MRCKb)DMPKAGC4uakABadenosine-5'-diphosphateHuman4863
ROCK1DMPKAGC4yveB2-(3-methoxyphenyl)-n-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]acetamideHuman2706
ROCK2DMPKAGC7jntAAn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12744
ROCK2DMPKAGC7jntEAn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12746
ROCK2DMPKAGC7jntEBn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12747
ROCK2DMPKAGC7jovCn-[(1s)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1h-pyrazol-4-yl)benzamideHuman12748
ROCK2DMPKAGC8x8zA~{n}-methyl-3-[[6-(3-methyl-1,2-oxazol-4-yl)-1-oxidanylidene-isoquinolin-2-yl]methyl]benzamideHuman15967
ROCK2DMPKAGC7jntFAn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12749
ROCK2DMPKAGC7jntDBn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12750
ROCK2DMPKAGC7jovHn-[(1s)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1h-pyrazol-4-yl)benzamideHuman12751
ROCK2DMPKAGC6ed6An-[(2,3-dihydro-1,4-benzodioxin-5-yl)methyl]-4-(pyridin-4-yl)benzamideHuman10689
ROCK2DMPKAGC6p5mAA6-(5-methyl-1h-pyrazol-4-yl)-2-[(pyrrolidin-1-yl)methyl]thieno[3,2-d]pyrimidin-4(3h)-oneHuman11920
ROCK2DMPKAGC7jntCAn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12752
ROCK2DMPKAGC8x8xA~{n}-methyl-3-[[1-oxidanylidene-6-[5-(trifluoromethyl)-1~{h}-pyrazol-4-yl]isoquinolin-2-yl]methyl]benzamideHuman15968
ROCK2DMPKAGC7jntHBn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12753
ROCK2DMPKAGC9hfpA~{n}-[4-[(3~{r})-piperidin-3-yl]oxyphenyl]-1~{h}-pyrrolo[2,3-b]pyridin-4-amineHuman15969
ROCK2DMPKAGC6p5mBA6-(5-methyl-1h-pyrazol-4-yl)-2-[(pyrrolidin-1-yl)methyl]thieno[3,2-d]pyrimidin-4(3h)-oneHuman11921
ROCK2DMPKAGC6p5pB2-[(2s)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1h-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3h)-oneHuman11923
ROCK2DMPKAGC7jntDAn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12755
ROCK2DMPKAGC7jntBAn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12756
ROCK2DMPKAGC6p5mBB6-(5-methyl-1h-pyrazol-4-yl)-2-[(pyrrolidin-1-yl)methyl]thieno[3,2-d]pyrimidin-4(3h)-oneHuman11924
ROCK2DMPKAGC7jovAn-[(1s)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1h-pyrazol-4-yl)benzamideHuman12757
ROCK2DMPKAGC9hjqA[3,3-bis(fluoranyl)azetidin-1-yl]-[1-methyl-6-[4-[[4-(1~{h}-pyrazol-4-yl)phenyl]amino]pyrimidin-2-yl]indol-2-yl]methanoneHuman15970
ROCK2DMPKAGC5u7rA(1s,4s)-4-(4-fluorophenyl)-4-hydroxy-6'-(5-methyl-1h-pyrazol-4-yl)-1'h-spiro[cyclohexane-1,2'-thieno[3,2-d]pyrimidin]-4'(3'h)-oneHuman7989
ROCK2DMPKAGC6p5mCA-Human11917
ROCK2DMPKAGC8x8yA3-fluoranyl-~{n}-methyl-5-[[1-oxidanylidene-6-[5-(trifluoromethyl)-1~{h}-pyrazol-4-yl]isoquinolin-2-yl]methyl]benzamideHuman15971
ROCK2DMPKAGC7jovFn-[(1s)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1h-pyrazol-4-yl)benzamideHuman12759
ROCK2DMPKAGC7jntHAn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12760
ROCK2DMPKAGC4l6qB6-[4-(aminomethyl)-2-fluorophenoxy]-2,1-benzoxaborol-1(3h)-olHuman1810
ROCK2DMPKAGC6p5mDB-Human11922
ROCK2DMPKAGC7jntGAn-[(3-methoxyphenyl)methyl]-5h-[1]benzopyrano[3,4-c]pyridine-8-carboxamideHuman12761
ROCK2DMPKAGC5u7rD(1s,4s)-4-(4-fluorophenyl)-4-hydroxy-6'-(5-methyl-1h-pyrazol-4-yl)-1'h-spiro[cyclohexane-1,2'-thieno[3,2-d]pyrimidin]-4'(3'h)-oneHuman7985
ROCK2DMPKAGC6p5mCB-Human11916
ROCK2DMPKAGC6ed6Bn-[(2,3-dihydro-1,4-benzodioxin-5-yl)methyl]-4-(pyridin-4-yl)benzamideHuman10688
ROCK2DMPKAGC4wotCmethyl 3-[({2'-(aminomethyl)-5'-[(3-fluoropyridin-4-yl)carbamoyl]biphenyl-3-yl}carbonyl)amino]-4-fluorobenzoateHuman6828
ROCK2DMPKAGC4wotDmethyl 3-[({2'-(aminomethyl)-5'-[(3-fluoropyridin-4-yl)carbamoyl]biphenyl-3-yl}carbonyl)amino]-4-fluorobenzoateHuman6830
ROCK2DMPKAGC8gdsA4-{4-[2-(2,3-dihydro-1h-indol-1-yl)-2-oxoethyl]phenyl}phthalazin-1(2h)-oneHuman14736
ROCK1DMPKAGC4w7pDn~1~-[2-(1h-indazol-5-yl)pyrido[3,4-d]pyrimidin-4-yl]-2-methylpropane-1,2-diamineHuman2712
ROCK1DMPKAGC5wnfCA1-(4-amino-1,2,5-oxadiazol-3-yl)-5-methyl-n-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)-1h-1,2,3-triazole-4-carboxamideHuman10455
ROCK1DMPKAGC6e9wBn-[(2,3-dihydro-1,4-benzodioxin-5-yl)methyl]-4-(pyridin-4-yl)benzamideHuman10690
ROCK1DMPKAGC3d9vB(s)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazineHuman2701
ROCK1DMPKAGC3v8sA1-(1h-indazol-5-yl)-3-(2-phenylethyl)ureaHuman2716
ROCK1DMPKAGC5kksA2-[3-(methylsulfonylamino)phenyl]-~{n}-[4-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)-1,3-thiazol-2-yl]ethanamideHuman8183
ROCK1DMPKAGC5wnhA(2r)-n-(3-cyanophenyl)-2-{3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}pyrrolidine-1-carboxamideHuman10448
ROCK1DMPKAGC5wngB(2r)-n-(3-cyanophenyl)-2-(3-{[(6s)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]carbamoyl}phenyl)pyrrolidine-1-carboxamideHuman10461
ROCK1DMPKAGC5wngC(2r)-n-(3-cyanophenyl)-2-(3-{[(6s)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]carbamoyl}phenyl)pyrrolidine-1-carboxamideHuman10458
ROCK1DMPKAGC3v8sD1-(1h-indazol-5-yl)-3-(2-phenylethyl)ureaHuman2692
ROCK1DMPKAGC3twjA1-[(3-hydroxyphenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)ureaHuman2710
ROCK1DMPKAGC8zh5A-Human15364
ROCK1DMPKAGC2esmB5-(1,4-diazepan-1-sulfonyl)isoquinolineHuman2714
ROCK1DMPKAGC3nczCcis-4-amino-n-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)cyclohexanecarboxamideHuman2719
ROCK1DMPKAGC2v55Cphosphoaminophosphonic acid-adenylate esterHuman2711
ROCK1DMPKAGC5wngD(2r)-n-(3-cyanophenyl)-2-(3-{[(6s)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]carbamoyl}phenyl)pyrrolidine-1-carboxamideHuman10457
ROCK1DMPKAGC5uzjBn-[4-(2-aminopyridin-4-yl)-1,3-thiazol-2-yl]-2-(3-methoxyphenyl)acetamideHuman9707
ROCK1DMPKAGC3tv7A1-[(1r)-1-(3-methoxyphenyl)ethyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)ureaHuman2697
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