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Search results (73 entries covering 36 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetails File
HASPIN (Haspin)HaspinOther6z56AC6-(2-methoxyethoxy)-11-methyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one Human12320
HASPIN (Haspin)HaspinOther6g37AB5-fluorotubercidinHuman9845
HASPIN (Haspin)HaspinOther4qtcAA(3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamideHuman3805
HASPIN (Haspin)HaspinOther6z5dAB11-methyl-8,11,14,18,19,22-hexazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2(23),3,5,15(22),16,19-heptaen-7-one Human12330
HASPIN (Haspin)HaspinOther6z5bAA6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one Human12331
HASPIN (Haspin)HaspinOther6g3aAB(2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diolHuman9835
HASPIN (Haspin)HaspinOther6g38AB'2-(4-amino-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diolHuman9842
HASPIN (Haspin)HaspinOther2vuwAB(2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diolHuman3801
HASPIN (Haspin)HaspinOther2wb8AB-Human3815
HASPIN (Haspin)HaspinOther7opsA2-methylsulfanyl-10-nitro-pyrido[3,4-g]quinazolineHuman13815
HASPIN (Haspin)HaspinOther7sqmAA1-[(4s)-5-(2,4-difluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-4-methylpiperidin-4-amineHuman14033
HASPIN (Haspin)HaspinOther6g34AB(2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diolHuman9846
HASPIN (Haspin)HaspinOther6g39AC-Human9838
HASPIN (Haspin)HaspinOther6z56AB6-(2-methoxyethoxy)-11-methyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one Human12333
HASPIN (Haspin)HaspinOther6z5bAB6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one Human12334
HASPIN (Haspin)HaspinOther8rdkA3-pyridin-4-yl-1~{h}-pyrrolo[3,2-g]isoquinolineHuman15259
HASPIN (Haspin)HaspinOther6g38AA'2-(4-amino-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diolHuman9830
HASPIN (Haspin)HaspinOther6g35AA5-bromotubercidinHuman9843
HASPIN (Haspin)HaspinOther9flcAA5-(1-methylpyrazol-3-yl)-3-pyridin-4-yl-thieno[3,2-b]pyridineHuman16112
HASPIN (Haspin)HaspinOther6g37AA5-fluorotubercidinHuman9840
HASPIN (Haspin)HaspinOther9b2tK-Human16113
HASPIN (Haspin)HaspinOther7avqAA(2~{r})-2-[[3-(2~{h}-indazol-5-yl)imidazo[1,2-b]pyridazin-6-yl]amino]butan-1-olHuman13176
HASPIN (Haspin)HaspinOther6z5eAB11-cyclopropyl-14-(2-hydroxyethyl)-8,11,14,18,19,22-hexazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2(23),3,5,15(22),16,19-heptaen-7-one Human12329
HASPIN (Haspin)HaspinOther6z57AA10-(2-morpholin-4-ylethyl)-7-oxa-10,13,17,18,21-pentazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaeneHuman12321
HASPIN (Haspin)HaspinOther6z59AB11-oxa-8,14,18,19,22-pentazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2,4,6(23),15(22),16,19-heptaen-7-oneHuman12316
HASPIN (Haspin)HaspinOther4oucAA(2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diolHuman3806
HASPIN (Haspin)HaspinOther3f2nAB(2s)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-olHuman3813
HASPIN (Haspin)HaspinOther6z5eAA11-cyclopropyl-14-(2-hydroxyethyl)-8,11,14,18,19,22-hexazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2(23),3,5,15(22),16,19-heptaen-7-one Human12317
HASPIN (Haspin)HaspinOther6z5cAB7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxylic acidHuman12318
HASPIN (Haspin)HaspinOther9floA~{n}-(1,4-dimethylpyrazol-3-yl)-3-(1,2-thiazol-5-yl)thieno[3,2-b]pyridin-5-amineHuman16109
HASPIN (Haspin)HaspinOther7sqmAB1-[(4s)-5-(2,4-difluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-4-methylpiperidin-4-amineHuman14032
HASPIN (Haspin)HaspinOther6g39AA(2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diolHuman9839
HASPIN (Haspin)HaspinOther6z5cAA7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxylic acidHuman12319
HASPIN (Haspin)HaspinOther5htbAA-Human6620
HASPIN (Haspin)HaspinOther9flbAA5-(1-methylpyrazol-4-yl)-3-pyridin-4-yl-thieno[3,2-b]pyridineHuman16110
HASPIN (Haspin)HaspinOther9fltA~{n}-(1,4-dimethylpyrazol-3-yl)-3-pyridin-4-yl-thieno[3,2-b]pyridin-5-amineHuman16111
HASPIN (Haspin)HaspinOther3f2nAA(2s)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-olHuman3803
HASPIN (Haspin)HaspinOther6z56AA6-(2-methoxyethoxy)-11-methyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one Human12322
HASPIN (Haspin)HaspinOther9flbAB5-(1-methylpyrazol-4-yl)-3-pyridin-4-yl-thieno[3,2-b]pyridineHuman16114
HASPIN (Haspin)HaspinOther7avqAB(2~{r})-2-[[3-(2~{h}-indazol-5-yl)imidazo[1,2-b]pyridazin-6-yl]amino]butan-1-olHuman13175
HASPIN (Haspin)HaspinOther6z57AB10-(2-morpholin-4-ylethyl)-7-oxa-10,13,17,18,21-pentazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaeneHuman12323
HASPIN (Haspin)HaspinOther2vuwAA(2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diolHuman3809
HASPIN (Haspin)HaspinOther5htcAB-Human6446
HASPIN (Haspin)HaspinOther3e7vAA3-(3-aminophenyl)-n-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-amineHuman3814
HASPIN (Haspin)HaspinOther6z5aABn-cyclopentyl-2-[(11,15-dimethyl-10-oxo-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-6-yl)oxy]acetamide Human12324
HASPIN (Haspin)HaspinOther6g35AD-Human9829
HASPIN (Haspin)HaspinOther3fmdABn-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamideHuman3810
HASPIN (Haspin)HaspinOther6g36AB5-chlorotubercidinHuman9844
HASPIN (Haspin)HaspinOther9flcAB5-(1-methylpyrazol-3-yl)-3-pyridin-4-yl-thieno[3,2-b]pyridineHuman16115
HASPIN (Haspin)HaspinOther3dlzABadenosine monophosphateHuman3808
HASPIN (Haspin)HaspinOther5htcAC-Human6444
HASPIN (Haspin)HaspinOther6g36AA5-chlorotubercidinHuman9834
HASPIN (Haspin)HaspinOther6g35AB5-bromotubercidinHuman9841
HASPIN (Haspin)HaspinOther6g3aAA(2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diolHuman9836
HASPIN (Haspin)HaspinOther5htbAB-Human6621
HASPIN (Haspin)HaspinOther5htcAA-Human6445
HASPIN (Haspin)HaspinOther6g39AB(2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diolHuman9831
HASPIN (Haspin)HaspinOther6z5dAA11-methyl-8,11,14,18,19,22-hexazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2(23),3,5,15(22),16,19-heptaen-7-one Human12325
HASPIN (Haspin)HaspinOther6z59AA11-oxa-8,14,18,19,22-pentazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2,4,6(23),15(22),16,19-heptaen-7-oneHuman12326
HASPIN (Haspin)HaspinOther2wb8AA-Human3802
HASPIN (Haspin)HaspinOther3e7vAB3-(3-aminophenyl)-n-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-amineHuman3799
HASPIN (Haspin)HaspinOther6z58AA8,14,18,19,22-pentazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2,4,6(23),15(22),16,19-heptaen-7-oneHuman12327
HASPIN (Haspin)HaspinOther6g39AD-Human9833
HASPIN (Haspin)HaspinOther3iq7AA(2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diolHuman3807
HASPIN (Haspin)HaspinOther6g35AC-Human9837
HASPIN (Haspin)HaspinOther6z5aAAn-cyclopentyl-2-[(11,15-dimethyl-10-oxo-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-6-yl)oxy]acetamide Human12328
HASPIN (Haspin)HaspinOther4oucAB(2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diolHuman3812
HASPIN (Haspin)HaspinOther3fmdAAn-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamideHuman3798
HASPIN (Haspin)HaspinOther6g34AA(2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diolHuman9832
HASPIN (Haspin)HaspinOther3dlzAAadenosine monophosphateHuman3804
HASPIN (Haspin)HaspinOther6z58AB8,14,18,19,22-pentazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2,4,6(23),15(22),16,19-heptaen-7-oneHuman12332
HASPIN (Haspin)HaspinOther4qtcAB(3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamideHuman3800
HASPIN (Haspin)HaspinOther3iq7AB(2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diolHuman3811
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