| MAPK3 (Erk1) | MAPK | CMGC | 2zoq | A | | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 1716 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8pt5 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 15306 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8pst | A | A | amp phosphoramidate | Human | 15311 | |
| MAPK14 (p38a) | MAPK | CMGC | 3k3i | A | A | (3s)-3-[4-(4-bromophenyl)-1h-imidazol-2-yl]-1,2,3,4-tetrahydroisoquinoline | Human | 5212 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8pt0 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 15297 | |
| MAPK14 (p38a) | MAPK | CMGC | 1bl7 | A | | 4-(4-fluorophenyl)-1-(4-piperidinyl)-5-(2-amino-4-pyrimidinyl)-imidazole | Human | 5193 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8ao6 | A | B | ~{n}-(1~{h}-indazol-5-ylmethyl)ethanamide | Human | 14396 | |
| MAPK9 (JNK2) | MAPK | CMGC | 7n8t | A | B | adenosine monophosphate | Human | 14242 | |
| MAPK11 (p38b) | MAPK | CMGC | 3gc8 | A | | 5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-[1-(1-methylethyl)piperidin-4-yl]-3,4-dihydroquinazolin-2(1h)-one | Human | 2766 | |
| MAPK11 (p38b) | MAPK | CMGC | 3gc9 | B | | 5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-[1-(1-methylethyl)piperidin-4-yl]-3,4-dihydroquinazolin-2(1h)-one | Human | 2767 | |
| MAPK11 (p38b) | MAPK | CMGC | 3gc9 | A | | 5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-[1-(1-methylethyl)piperidin-4-yl]-3,4-dihydroquinazolin-2(1h)-one | Human | 2765 | |
| MAPK11 (p38b) | MAPK | CMGC | 3gc8 | B | | 5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-[1-(1-methylethyl)piperidin-4-yl]-3,4-dihydroquinazolin-2(1h)-one | Human | 2769 | |
| MAPK11 (p38b) | MAPK | CMGC | 3gp0 | A | B | nilotinib | Human | 2764 | |
| MAPK11 (p38b) | MAPK | CMGC | 3gp0 | A | A | nilotinib | Human | 2768 | |
| MAPK7 (Erk5) | MAPK | CMGC | 5byy | A | A | 2-{[2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl]amino}-5,11-dimethyl-5,11-dihydro-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one | Human | 6591 | |
| MAPK7 (Erk5) | MAPK | CMGC | 5o7i | A | A | 4-(2-bromanyl-6-fluoranyl-phenyl)carbonyl-~{n}-pyridin-3-yl-1~{h}-pyrrole-2-carboxamide | Human | 9995 | |
| MAPK7 (Erk5) | MAPK | CMGC | 7pus | A | B | 4-[3,6-bis(chloranyl)-2-fluoranyl-phenyl]carbonyl-~{n}-(1-methylpyrazol-4-yl)-1~{h}-pyrrole-2-carboxamide | Human | 14219 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4iz7 | A | B | - | Human | 2577 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7nr5 | A | B | (2~{r})-2-[5-[5-chloranyl-2-[(2-methyl-1,2,3-triazol-4-yl)amino]pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{s})-1-(3-fluoranyl-5-methoxy-phenyl)-2-oxidanyl-ethyl]propanamide | Human | 13934 | |
| MAPK1 (Erk2) | MAPK | CMGC | 1wzy | A | | 1-allyl-5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1h-pyrazolo[3,4-c]pyridazin-3-amine | Human | 2618 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4g6n | A | B | 3-(4-chlorophenyl)-4,5,6,7-tetrahydro-1h-indazole | Human | 2593 | |
| MAPK8 (JNK1) | MAPK | CMGC | 3o2m | B | | - | Human | 4649 | |
| MAPK8 (JNK1) | MAPK | CMGC | 2xrw | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 4675 | |
| MAPK8 (JNK1) | MAPK | CMGC | 3vul | A | | - | Human | 4633 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5wp1 | A | A | 5,7-dihydroxy-4h-1-benzopyran-4-one | Human | 10441 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4ux9 | D | B | phosphoaminophosphonic acid-adenylate ester | Human | 4666 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4yr8 | C | B | - | Human | 6447 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7nqq | A | A | 2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{s})-1-(hydroxymethyl)-2,3-dihydroinden-1-yl]ethanamide | Human | 13926 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7nr9 | A | A | (2~{r})-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{s})-1-(2-methoxypyridin-4-yl)-2-oxidanyl-ethyl]propanamide | Human | 13932 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8ao3 | A | A | 2-chloranyl-~{n}-(1~{h}-indazol-5-ylmethyl)ethanamide | Human | 14386 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aoi | A | A | 1-(2,3-dihydropyrido[2,3-b][1,4]oxazin-1-yl)propan-1-one | Human | 14387 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aod | A | A | 1-(3-oxidanyl-2~{h}-quinoxalin-1-yl)propan-1-one | Human | 14417 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4ux9 | C | B | phosphoaminophosphonic acid-adenylate ester | Human | 4647 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4l7f | A | B | n-[1-(4-fluorophenyl)cyclopropyl]-4-[(trans-4-hydroxycyclohexyl)amino]imidazo[1,2-a]quinoxaline-8-carboxamide | Human | 4637 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8pt5 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 15301 | |
| MAPK8 (JNK1) | MAPK | CMGC | 2g01 | A | | 6-chloro-9-hydroxy-1,3-dimethyl-1,9-dihydro-4h-pyrazolo[3,4-b]quinolin-4-one | Human | 4662 | |
| MAPK8 (JNK1) | MAPK | CMGC | 3o17 | A | | - | Human | 4670 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8ao9 | A | C | 1-(6,7-dihydro-4~{h}-[1,3]thiazolo[5,4-c]pyridin-5-yl)propan-1-one | Human | 14401 | |
| MAPK8 (JNK1) | MAPK | CMGC | 2no3 | B | | 2-({2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}amino)benzamide | Human | 4657 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8ao9 | A | B | 1-(6,7-dihydro-4~{h}-[1,3]thiazolo[5,4-c]pyridin-5-yl)propan-1-one | Human | 14390 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aoj | A | A | 1-[(2~{s})-2-(5-methyl-3-pyridin-4-yl-1~{h}-pyrazol-4-yl)pyrrolidin-1-yl]propan-1-one | Human | 14412 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aoj | A | B | - | Human | 14418 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8ao9 | A | A | 1-(6,7-dihydro-4~{h}-[1,3]thiazolo[5,4-c]pyridin-5-yl)propan-1-one | Human | 14420 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8psy | A | | amp phosphoramidate | Human | 15308 | |
| MAPK8 (JNK1) | MAPK | CMGC | 3v3v | A | | 3,5,6,7-tetrahydroxy-2-(3,4-dihydroxyphenyl)-4h-chromen-4-one | Human | 4653 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4yr8 | F | B | - | Human | 6453 | |
| MAPK14 (p38a) | MAPK | CMGC | 3heg | A | A | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 5112 | |
| MAPK8 (JNK1) | MAPK | CMGC | 3vug | A | | - | Human | 4665 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aoa | A | A | ~{n}-pyridin-3-ylprop-2-enamide | Human | 14391 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8ao5 | A | A | ~{n}-(1~{h}-indazol-5-ylmethyl)ethanesulfonamide | Human | 14392 | |
| MAPK10 (JNK3) | MAPK | CMGC | 7s1n | A | A | 4-[5-(2-chloro-6-fluoroanilino)-6-methyl-1h-pyrazolo[3,4-b]pyridin-1-yl]-n-(oxetan-3-yl)thiophene-2-carboxamide | Human | 13958 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8pt1 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 15302 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aog | A | B | ~{n}-(5-methyl-1,2-oxazol-3-yl)propanamide | Human | 14421 | |
| MAPK10 (JNK3) | MAPK | CMGC | 7s1n | A | B | 4-[5-(2-chloro-6-fluoroanilino)-6-methyl-1h-pyrazolo[3,4-b]pyridin-1-yl]-n-(oxetan-3-yl)thiophene-2-carboxamide | Human | 13957 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7nr8 | A | A | (2~{r})-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{s})-1-[6-(4-methylpiperazin-1-yl)pyridin-2-yl]-2-oxidanyl-ethyl]propanamide | Human | 13933 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aoh | A | B | ~{n}-(6,7-dihydro-4~{h}-pyrano[4,3-d][1,3]thiazol-2-yl)propanamide | Human | 14404 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8pt3 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 15305 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4awi | A | B | n-(1,1-dioxidotetrahydro-2h-thiopyran-4-yl)-4-[2-(1-methylethyl)-1h-pyrrolo[2,3-b]pyridin-4-yl]benzenesulfonamide | Human | 4634 | |
| MAPK8 (JNK1) | MAPK | CMGC | 6zr5 | A | | phosphoaminophosphonic acid-adenylate ester | Human | 12984 | |
| MAPK7 (Erk5) | MAPK | CMGC | 9lta | A | | 4-[5-chloranyl-2-[[3-[(dimethylamino)methyl]phenyl]amino]pyrimidin-4-yl]-~{n}-morpholin-4-yl-thiophene-2-carboxamide | Human | 15439 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8u8j | A | | (4m)-4-{(4r)-3-[(2s)-2-methylbutyl][1,2,4]triazolo[4,3-a]pyridin-7-yl}-n-(1-methyl-1h-pyrazol-5-yl)pyrimidin-2-amine | Human | 15224 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8u8k | A | | (4m)-4-{(4s)-3-[(2-chloropyridin-3-yl)methyl][1,2,4]triazolo[4,3-a]pyridin-7-yl}-n-(oxan-4-yl)pyrimidin-2-amine | Human | 15225 | |
| MAPK1 (Erk2) | MAPK | CMGC | 9tyh | A | | adenosine-5'-diphosphate | Human | 15552 | |
| MAPK1 (Erk2) | MAPK | CMGC | 9tyg | B | | adenosine-5'-diphosphate | Human | 15553 | |
| MAPK1 (Erk2) | MAPK | CMGC | 9tyi | A | | - | Human | 15554 | |
| MAPK11 (p38b) | MAPK | CMGC | 8ygw | A | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 15234 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5v61 | A | A | - | Human | 8265 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6nbs | A | A | - | Human | 11510 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8ao8 | A | B | 1-[(2~{r})-2-(3-methylimidazol-4-yl)piperidin-1-yl]propan-1-one | Human | 14405 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8ao8 | A | A | 1-[(2~{r})-2-(3-methylimidazol-4-yl)piperidin-1-yl]propan-1-one | Human | 14410 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8ao2 | A | A | ~{n}-(1~{h}-indazol-5-ylmethyl)propanamide | Human | 14415 | |
| MAPK7 (Erk5) | MAPK | CMGC | 7pus | A | A | 4-[3,6-bis(chloranyl)-2-fluoranyl-phenyl]carbonyl-~{n}-(1-methylpyrazol-4-yl)-1~{h}-pyrrole-2-carboxamide | Human | 14218 | |
| MAPK7 (Erk5) | MAPK | CMGC | 6hkn | A | A | [2-azanyl-4-(trifluoromethyloxy)phenyl]-[4-(7-methoxyquinazolin-4-yl)piperidin-1-yl]methanone | Human | 10918 | |
| MAPK7 (Erk5) | MAPK | CMGC | 4ic7 | D | | phosphoaminophosphonic acid-adenylate ester | Human | 391 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4g6n | A | A | 3-(4-chlorophenyl)-4,5,6,7-tetrahydro-1h-indazole | Human | 2609 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bve | A | A | 2-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-8-[2-(tetrahydro-2h-pyran-4-ylamino)pyrimidin-4-yl]-2,3,4,5-tetrahydro-1h-pyrrolo[1,2-a][1,4]diazepin-1-one | Human | 6029 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bvd | A | B | 2-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-7-[2-(tetrahydro-2h-pyran-4-ylamino)pyrimidin-4-yl]-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2h)-one | Human | 6028 | |
| MAPK7 (Erk5) | MAPK | CMGC | 6hkn | A | B | [2-azanyl-4-(trifluoromethyloxy)phenyl]-[4-(7-methoxyquinazolin-4-yl)piperidin-1-yl]methanone | Human | 10919 | |
| MAPK3 (Erk1) | MAPK | CMGC | 9uux | B | | phosphoaminophosphonic acid-adenylate ester | Human | 16039 | |
| MAPK3 (Erk1) | MAPK | CMGC | 9uur | B | | phosphoaminophosphonic acid-adenylate ester | Human | 16040 | |
| MAPK3 (Erk1) | MAPK | CMGC | 9tu0 | A | | - | Human | 16041 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4yr8 | C | A | - | Human | 6449 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4x21 | A | | n-ethyl-4-{[4-(1h-indol-3-yl)-5-iodopyrimidin-2-yl]amino}piperidine-1-carboxamide | Human | 6240 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aod | A | B | 1-(3-oxidanyl-2~{h}-quinoxalin-1-yl)propan-1-one | Human | 14388 | |
| MAPK12 (p38g) | MAPK | CMGC | 6una | A | B | - | Human | 11900 | |
| MAPK12 (p38g) | MAPK | CMGC | 6una | B | A | - | Human | 11901 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5buj | A | A | 4-[3-(pyridin-4-yl)-2,4,6,7-tetrahydro-5h-pyrazolo[4,3-c]pyridin-5-yl]pyridin-2(1h)-one | Human | 2560 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aoc | A | A | ~{n}-(3-methyl-[1,2]oxazolo[5,4-b]pyridin-5-yl)propanamide | Human | 14409 | |
| MAPK1 (Erk2) | MAPK | CMGC | 2y9q | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 2626 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4h36 | A | B | - | Human | 3461 | |
| MAPK14 (p38a) | MAPK | CMGC | 6hwu | A | B | - | Human | 11249 | |
| MAPK14 (p38a) | MAPK | CMGC | 4zth | A | B | 6-chloro-3-phenyl-4-(pyridin-4-yl)pyridazine | Human | 6707 | |
| MAPK8 (JNK1) | MAPK | CMGC | 1ukh | A | | - | Human | 4628 | |
| MAPK8 (JNK1) | MAPK | CMGC | 2h96 | A | | 5-cyano-n-(2,5-dimethoxybenzyl)-6-ethoxypyridine-2-carboxamide | Human | 4655 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4qtd | A | A | (3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamide | Human | 4651 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4g1w | A | | methyl 7-fluoro-3-{4-[(2-hydroxyethyl)sulfonyl]benzyl}-4-oxo-1-phenyl-1,4-dihydroquinoline-2-carboxylate | Human | 4631 | |
| MAPK8 (JNK1) | MAPK | CMGC | 2xs0 | A | | phosphoaminophosphonic acid-adenylate ester | Human | 4629 | |
| MAPK8 (JNK1) | MAPK | CMGC | 2gmx | B | | n-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-bromo-2,5-dimethoxyphenyl)acetamide | Human | 4638 | |
| MAPK8 (JNK1) | MAPK | CMGC | 1uki | A | | 2,6-dihydroanthra/1,9-cd/pyrazol-6-one | Human | 4630 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4yr8 | E | A | - | Human | 6451 | |
| MAPK8 (JNK1) | MAPK | CMGC | 6zr5 | B | | phosphoaminophosphonic acid-adenylate ester | Human | 12985 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4hys | A | | trans-4-{[4-(1h-indazol-1-yl)pyrimidin-2-yl]amino}cyclohexanol | Human | 4672 | |
| MAPK8 (JNK1) | MAPK | CMGC | 3vui | A | | - | Human | 4652 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4ux9 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 4646 | |
| MAPK8 (JNK1) | MAPK | CMGC | 2xrw | A | C | phosphoaminophosphonic acid-adenylate ester | Human | 4660 | |
| MAPK8 (JNK1) | MAPK | CMGC | 3vud | A | | - | Human | 4664 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fmn | A | A | 6-(2,4-difluorophenoxy)-n-(tetrahydro-2h-pyran-4-yl)-1h-pyrazolo[3,4-d]pyrimidin-3-amine | Human | 5196 | |
| MAPK7 (Erk5) | MAPK | CMGC | 4zsj | A | B | 3-amino-5-[(4-chloro-3-methylphenyl)amino]-n-(propan-2-yl)-1h-1,2,4-triazole-1-carboxamide | Human | 6585 | |
| MAPK7 (Erk5) | MAPK | CMGC | 4ic7 | A | | phosphoaminophosphonic acid-adenylate ester | Human | 392 | |
| MAPK14 (p38a) | MAPK | CMGC | 2lgc | A | 4 | - | Human | 5067 | |
| MAPK7 (Erk5) | MAPK | CMGC | 5o7i | A | B | 4-(2-bromanyl-6-fluoranyl-phenyl)carbonyl-~{n}-pyridin-3-yl-1~{h}-pyrrole-2-carboxamide | Human | 9994 | |
| MAPK7 (Erk5) | MAPK | CMGC | 5byy | A | B | 2-{[2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl]amino}-5,11-dimethyl-5,11-dihydro-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one | Human | 6587 | |
| MAPK7 (Erk5) | MAPK | CMGC | 4zsl | A | | 3-amino-5-[(4-chlorophenyl)amino]-n-[(1s)-1-phenylethyl]-1h-1,2,4-triazole-1-carboxamide | Human | 6586 | |
| MAPK7 (Erk5) | MAPK | CMGC | 4zsg | A | B | 3-amino-5-[(4-chlorophenyl)amino]-n-(propan-2-yl)-1h-1,2,4-triazole-1-carboxamide | Human | 6584 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hv7 | A | | 1-[1-(3-aminophenyl)-3-tert-butyl-1h-pyrazol-5-yl]-3-naphthalen-1-ylurea | Human | 5223 | |
| MAPK8 (JNK1) | MAPK | CMGC | 2no3 | A | | 2-({2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}amino)benzamide | Human | 4640 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5v62 | A | B | 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1h-pyrazolo[3,4-c]pyridazin-3-amine | Human | 8262 | |
| MAPK14 (p38a) | MAPK | CMGC | 2baj | A | | 1-(3-tert-butyl-1-phenyl-1h-pyrazol-5-yl)-3-(2,3-dichlorophenyl)urea | Human | 5176 | |
| MAPK14 (p38a) | MAPK | CMGC | 3obj | A | | 1-(5-tert-butyl-2-methyl-2h-pyrazol-3-yl)-3-(4-chloro-phenyl)-urea | Human | 4994 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4g6o | A | | 4-{4-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]-1h-pyrazol-5-yl}-n-(2,3-dihydro-1-benzofuran-5-ylmethyl)-1h-pyrrole-2-carboxamide | Human | 2565 | |
| MAPK14 (p38a) | MAPK | CMGC | 3zsg | A | A | tak-715 | Human | 5033 | |
| MAPK14 (p38a) | MAPK | CMGC | 2i0h | A | A | 2-(3-{(2-chloro-4-fluorophenyl)[1-(2-chlorophenyl)-6-oxo-1,6-dihydropyridazin-3-yl]amino}propyl)-1h-isoindole-1,3(2h)-dione | Human | 5062 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8ao7 | A | A | ~{n}-[(1-methylindazol-6-yl)methyl]propanamide | Human | 14389 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aoi | A | B | 1-(2,3-dihydropyrido[2,3-b][1,4]oxazin-1-yl)propan-1-one | Human | 14393 | |
| MAPK14 (p38a) | MAPK | CMGC | 4aac | A | | n-isoxazol-3-yl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxo-quinazolin-3-yl]benzamide | Human | 5048 | |
| MAPK14 (p38a) | MAPK | CMGC | 1r3c | A | B | - | Human | 4996 | |
| MAPK14 (p38a) | MAPK | CMGC | 3c5u | A | | 6-[4-(2-fluorophenyl)-1,3-oxazol-5-yl]-n-(1-methylethyl)-1,3-benzothiazol-2-amine | Human | 5125 | |
| MAPK14 (p38a) | MAPK | CMGC | 3oc1 | A | | 1-(5-tert-butyl-2-methyl-2h-pyrazol-3-yl)-3-(4-chloro-phenyl)-urea | Human | 5019 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv4 | A | A | 9-(dimethylamino)-2-[(3-hydroxyphenyl)amino]-5,6-dihydrothieno[3,4-h]quinazoline-7-carbonitrile | Human | 2623 | |
| MAPK14 (p38a) | MAPK | CMGC | 3obg | A | | 4-[5-(4-fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-3h-imidazol-4-yl]-pyridine | Human | 5211 | |
| MAPK7 (Erk5) | MAPK | CMGC | 6hkm | A | | [4-(6,7-dimethoxyquinazolin-4-yl)piperidin-1-yl]-[4-(trifluoromethyloxy)phenyl]methanone | Human | 10917 | |
| MAPK14 (p38a) | MAPK | CMGC | 5mz3 | A | B | ~{n}-[3-(2-acetamidoimidazo[1,2-a]pyridin-6-yl)-4-methyl-phenyl]-3-(trifluoromethyl)benzamide | Human | 8681 | |
| MAPK14 (p38a) | MAPK | CMGC | 5wjj | A | A | n-{4-[2-(4-fluoro-3-methylphenyl)imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl}-2-methyl-1-oxo-1lambda~5~-pyridine-4-carboxamide | Human | 9514 | |
| MAPK9 (JNK2) | MAPK | CMGC | 8elc | A | | 4-(dimethylamino)-n-{4-[(3s)-3-({4-[(8r)-2-phenylpyrazolo[1,5-a]pyridin-3-yl]pyrimidin-2-yl}amino)pyrrolidine-1-carbonyl]phenyl}butanamide | Human | 14816 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4awi | A | A | n-(1,1-dioxidotetrahydro-2h-thiopyran-4-yl)-4-[2-(1-methylethyl)-1h-pyrrolo[2,3-b]pyridin-4-yl]benzenesulfonamide | Human | 4661 | |
| MAPK8 (JNK1) | MAPK | CMGC | 6f5e | B | | - | Human | 9078 | |
| MAPK14 (p38a) | MAPK | CMGC | 2fso | X | | - | Human | 5117 | |
| MAPK14 (p38a) | MAPK | CMGC | 3qud | A | A | {4-[(2-aminophenyl)amino]phenyl}(phenyl)methanone | Human | 5006 | |
| MAPK8 (JNK1) | MAPK | CMGC | 5lw1 | H | | adenosine | Human | 9080 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4ux9 | B | B | phosphoaminophosphonic acid-adenylate ester | Human | 4656 | |
| MAPK8 (JNK1) | MAPK | CMGC | 11zl | A | A | (4m)-n-[4-hydroxy-3-(pyrrolidine-1-carbonyl)phenyl]-4-(1h-pyrrolo[2,3-b]pyridin-5-yl)-1-benzothiophene-2-carboxamide | Human | 15534 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4e73 | A | B | methyl 3-(4-{[(1r,2s,3s,5s,7s)-5-aminotricyclo[3.3.1.1~3,7~]dec-2-yl]carbamoyl}benzyl)-4-oxo-1-phenyl-1,4-dihydro-1,8-naphthyridine-2-carboxylate | Human | 4669 | |
| MAPK8 (JNK1) | MAPK | CMGC | 5lw1 | E | | adenosine | Human | 9079 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4yr8 | E | B | - | Human | 6454 | |
| MAPK14 (p38a) | MAPK | CMGC | 3mh2 | A | | - | Human | 4985 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5wp1 | A | B | 5,7-dihydroxy-4h-1-benzopyran-4-one | Human | 10440 | |
| MAPK8 (JNK1) | MAPK | CMGC | 3o17 | B | | - | Human | 4667 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4yr8 | A | B | - | Human | 6448 | |
| MAPK3 (Erk1) | MAPK | CMGC | 4qtb | B | A | (3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamide | Human | 1717 | |
| MAPK8 (JNK1) | MAPK | CMGC | 3o2m | A | | - | Human | 4676 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4ux9 | D | A | phosphoaminophosphonic acid-adenylate ester | Human | 4627 | |
| MAPK12 (p38g) | MAPK | CMGC | 7cga | A | | - | Human | 13762 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4l7f | A | C | n-[1-(4-fluorophenyl)cyclopropyl]-4-[(trans-4-hydroxycyclohexyl)amino]imidazo[1,2-a]quinoxaline-8-carboxamide | Human | 4648 | |
| MAPK8 (JNK1) | MAPK | CMGC | 3vuk | A | | - | Human | 4659 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8psr | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 15298 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6slg | A | B | (6~{r})-7-[[3,4-bis(fluoranyl)phenyl]methyl]-6-(methoxymethyl)-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-5,6-dihydroimidazo[1,2-a]pyrazin-8-one | Human | 11816 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6ge0 | A | B | 2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{r})-1-(3-methoxyphenyl)ethyl]ethanamide | Human | 9961 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6q7k | A | | 1h-imidazol-2-amine | Human | 10985 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g8x | A | A | 4-chloranyl-1~{h}-indazol-3-amine | Human | 9957 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g9d | A | A | ~{n}-~{tert}-butyl-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]ethanamide | Human | 9972 | |
| MAPK9 (JNK2) | MAPK | CMGC | 3npc | B | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 1237 | |
| MAPK8 (JNK1) | MAPK | CMGC | 2h96 | B | | 5-cyano-n-(2,5-dimethoxybenzyl)-6-ethoxypyridine-2-carboxamide | Human | 4668 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8pst | A | B | amp phosphoramidate | Human | 15299 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qp3 | A | | (2s)-3-phenyl-2-(9h-purin-6-ylamino)propan-1-ol | Human | 6084 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qp7 | A | | 2-(1h-pyrazol-4-yl)-5h-pyrrolo[2,3-b]pyrazine | Human | 6082 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4zxt | A | A | catechol | Human | 6654 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g9h | A | A | ~{n}-~{tert}-butyl-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-methyl-ethanamide | Human | 9971 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8ao2 | A | B | ~{n}-(1~{h}-indazol-5-ylmethyl)propanamide | Human | 14394 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4iz5 | D | | adenosine-5'-diphosphate | Human | 2578 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bvf | A | A | 2-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-8-(2-{[(1s,3r)-3-hydroxycyclopentyl]amino}pyrimidin-4-yl)-2,3,4,5-tetrahydro-1h-pyrrolo[1,2-a][1,4]diazepin-1-one | Human | 6031 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5lck | A | B | ~{n}-[2-[[2-[(5-methoxypyridin-3-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]propanamide | Human | 6836 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g9n | A | B | (2~{r})-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{s})-1-(3-methylphenyl)-2-oxidanyl-ethyl]propanamide | Human | 11413 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fuy | A | A | {4-[4-(3,5-dichlorophenyl)-1h-pyrazol-5-yl]-1h-pyrrol-2-yl}(morpholin-4-yl)methanone | Human | 2622 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6qah | A | B | 1-azanylpropylideneazanium | Human | 11348 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qp8 | A | | 2-(1h-pyrazol-4-yl)-7-(pyridin-3-yl)-5h-pyrrolo[2,3-b]pyrazine | Human | 6087 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7opm | A | B | 1-[4-(hydroxymethyl)-1h-pyrazolo[4,3-c]pyridin-6-yl]-3-[(1s)-1-phenylethyl]urea | Human | 14083 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8ao7 | A | B | ~{n}-[(1-methylindazol-6-yl)methyl]propanamide | Human | 14398 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8ao4 | A | B | ~{n}-(1~{h}-indazol-5-yl)ethanesulfonamide | Human | 14399 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4zxt | A | B | catechol | Human | 6653 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4iza | C | B | - | Human | 2627 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6q7t | A | A | 1,2-oxazol-3-amine | Human | 11350 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g91 | A | B | 5-chloranyl-~{n}-(oxan-4-yl)pyrimidin-2-amine | Human | 9956 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6opg | A | | phosphoaminophosphonic acid-adenylate ester | Human | 11507 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8ao5 | A | B | ~{n}-(1~{h}-indazol-5-ylmethyl)ethanesulfonamide | Human | 14400 | |
| MAPK1 (Erk2) | MAPK | CMGC | 3tei | A | | phosphoaminophosphonic acid-adenylate ester | Human | 2608 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g54 | A | A | n-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propanamide | Human | 10938 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qta | A | A | (3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamide | Human | 2602 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aoc | A | B | ~{n}-(3-methyl-[1,2]oxazolo[5,4-b]pyridin-5-yl)propanamide | Human | 14406 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7e75 | A | | - | Human | 14115 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6gdq | A | A | 4-[5-chloranyl-2-(propan-2-ylamino)pyridin-4-yl]-~{n}-[(1~{s})-1-(3-chlorophenyl)-2-oxidanyl-ethyl]-1~{h}-pyrrole-2-carboxamide | Human | 9948 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bve | A | B | 2-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-8-[2-(tetrahydro-2h-pyran-4-ylamino)pyrimidin-4-yl]-2,3,4,5-tetrahydro-1h-pyrrolo[1,2-a][1,4]diazepin-1-one | Human | 6026 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aoa | A | B | ~{n}-pyridin-3-ylprop-2-enamide | Human | 14407 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g9a | A | A | 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2-(2-morpholin-4-ylethyl)-3~{h}-isoindol-1-one | Human | 11408 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5lck | A | A | ~{n}-[2-[[2-[(5-methoxypyridin-3-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]propanamide | Human | 6835 | |
| MAPK1 (Erk2) | MAPK | CMGC | 3w55 | A | | (3s,5z,8s,9s,11e)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1h-2-benzoxacyclotetradecine-1,7(8h)-dione | Human | 2573 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bue | A | | 1-benzyl-4-[3-(pyridin-4-yl)-2,4,6,7-tetrahydro-5h-pyrazolo[4,3-c]pyridin-5-yl]pyridin-2(1h)-one | Human | 2574 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7xc1 | A | | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 14665 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5nhf | A | | 2-[2-(oxan-4-ylamino)pyrimidin-4-yl]-5-(phenylmethyl)-6,7-dihydro-1~{h}-pyrrolo[3,2-c]pyridin-4-one | Human | 7997 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6gjb | A | A | [(1~{r},4~{z})-cyclooct-4-en-1-yl] ~{n}-[4-[4-[[4-[1-[(1~{s})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-2-oxidanylidene-pyridin-4-yl]pyrimidin-2-yl]amino]pyridin-2-yl]but-3-ynyl]carbamate | Human | 10832 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aoe | A | B | ~{n}-(1~{h}-pyrrolo[2,3-b]pyridin-4-yl)ethanesulfonamide | Human | 14411 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5v61 | A | B | - | Human | 8266 | |
| MAPK1 (Erk2) | MAPK | CMGC | 2y9q | A | C | phosphoaminophosphonic acid-adenylate ester | Human | 2567 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6qa3 | A | A | pyrazole | Human | 11353 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6rfo | A | | - | Human | 12341 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4xj0 | B | | 1-[(1s)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-(tetrahydro-2h-pyran-4-ylamino)pyrimidin-4-yl]pyridin-2(1h)-one | Human | 6049 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4iza | A | B | - | Human | 2607 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5v62 | A | A | 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1h-pyrazolo[3,4-c]pyridazin-3-amine | Human | 8264 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qp2 | B | | - | Human | 6081 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4n0s | A | B | caffeic acid | Human | 2555 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4zzm | A | | 7-ethylsulfonyl-n-(oxan-4-yl)-6,8-dihydro-5h-pyrido[3,4-d]pyrimidin-2-amine | Human | 2616 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8ao3 | A | B | 2-chloranyl-~{n}-(1~{h}-indazol-5-ylmethyl)ethanamide | Human | 14414 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6q7t | A | B | 1,2-oxazol-3-amine | Human | 11347 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5k4i | A | | 1-[(1~{s})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one | Human | 6744 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g9j | A | B | 2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{r})-1-phenylethyl]ethanamide | Human | 9949 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4iz7 | A | A | - | Human | 2615 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qta | A | B | (3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamide | Human | 2576 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aof | A | A | ~{n}-(2-methylpyrimidin-5-yl)propanamide | Human | 14419 | |
| MAPK1 (Erk2) | MAPK | CMGC | 3i5z | A | | n-[(1s)-2-hydroxy-1-phenylethyl]-4-[5-methyl-2-(phenylamino)pyrimidin-4-yl]-1h-pyrrole-2-carboxamide | Human | 2579 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aoe | A | A | ~{n}-(1~{h}-pyrrolo[2,3-b]pyridin-4-yl)ethanesulfonamide | Human | 14395 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4nif | B | A | phosphoaminophosphonic acid-adenylate ester | Human | 2585 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv5 | A | | n-[(1s)-2-hydroxy-1-phenylethyl]-4-(5-methyl-2-phenylpyrimidin-4-yl)-1h-pyrrole-2-carboxamide | Human | 2598 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8ao6 | A | A | ~{n}-(1~{h}-indazol-5-ylmethyl)ethanamide | Human | 14397 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv8 | A | A | 6-({4-[(3-cyclopropyl-1h-pyrazol-5-yl)amino]-5-(phenylamino)pyrimidin-2-yl}amino)-1,2-dihydro-3h-indazol-3-one | Human | 2625 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6dmg | A | A | - | Human | 10811 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4zzn | A | A | 2-[[5-chloranyl-2-(oxan-4-ylamino)pyridin-4-yl]amino]-n-methyl-benzamide | Human | 2605 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g9h | A | B | ~{n}-~{tert}-butyl-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-methyl-ethanamide | Human | 9958 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6slg | A | A | (6~{r})-7-[[3,4-bis(fluoranyl)phenyl]methyl]-6-(methoxymethyl)-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-5,6-dihydroimidazo[1,2-a]pyrazin-8-one | Human | 11815 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6gjb | A | B | [(1~{r},4~{z})-cyclooct-4-en-1-yl] ~{n}-[4-[4-[[4-[1-[(1~{s})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-2-oxidanylidene-pyridin-4-yl]pyrimidin-2-yl]amino]pyridin-2-yl]but-3-ynyl]carbamate | Human | 10831 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aob | A | B | ~{n}-[(1-methylindazol-3-yl)methyl]propanamide | Human | 14413 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6rq4 | A | A | 6,6-dimethyl-2-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-5-(2-morpholin-4-ylethyl)thieno[2,3-c]pyrrol-4-one | Human | 11854 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4ux9 | C | A | phosphoaminophosphonic acid-adenylate ester | Human | 4644 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3oxi | A | | methyl 3-[(thiophen-2-ylacetyl)amino]thiophene-2-carboxylate | Human | 3423 | |
| MAPK10 (JNK3) | MAPK | CMGC | 6emh | C | B | 4-(4-methyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amine | Human | 10505 | |
| MAPK9 (JNK2) | MAPK | CMGC | 3e7o | A | | n-{3-[5-(1h-1,2,4-triazol-3-yl)-1h-indazol-3-yl]phenyl}furan-2-carboxamide | Human | 1238 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7x4u | A | B | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 14661 | |
| MAPK9 (JNK2) | MAPK | CMGC | 7cml | A | B | - | Human | 12705 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7x4u | A | A | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 14660 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7opm | A | A | 1-[4-(hydroxymethyl)-1h-pyrazolo[4,3-c]pyridin-6-yl]-3-[(1s)-1-phenylethyl]urea | Human | 14084 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fko | A | | 3-(2-chlorophenyl)-6-(2-fluorophenoxy)-2h-indazole | Human | 5075 | |
| MAPK6 (Erk3) | MAPK | CMGC | 6ylc | C | | 5-fluoranyl-2-[5-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]benzenecarbonitrile | Human | 12794 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4h36 | A | A | - | Human | 3459 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4kke | A | | adenosine monophosphate | Human | 3448 | |
| MAPK10 (JNK3) | MAPK | CMGC | 6emh | D | B | 4-(4-methyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amine | Human | 10496 | |
| MAPK10 (JNK3) | MAPK | CMGC | 6eq9 | B | A | phosphomethylphosphonic acid adenylate ester | Human | 10504 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3cgf | A | | n-cyclohexyl-4-imidazo[1,2-a]pyridin-3-yl-n-methylpyrimidin-2-amine | Human | 6770 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4y5h | A | | 1-(trans-4-{[7-oxo-8-(propan-2-yl)-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}cyclohexyl)-3-propan-2-ylurea | Human | 3431 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4whz | A | A | 3-(4-{[(2-chlorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-n-{1-[(3s)-pyrrolidin-3-yl]-1h-pyrazol-4-yl}benzamide | Human | 3429 | |
| MAPK10 (JNK3) | MAPK | CMGC | 8vo4 | A | | (4p)-4-{6-[(azetidin-1-yl)methyl]-5-(2-chloro-6-fluoroanilino)-1h-indazol-1-yl}-n-methylthiophene-2-carboxamide | Human | 15637 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4w4w | A | | n-(2-methylpyridin-4-yl)-3-{4-[(phenylcarbamoyl)amino]-1h-pyrazol-1-yl}benzamide | Human | 3418 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3v6r | A | B | 4-{[4-(dimethylamino)butanoyl]amino}-n-(3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide | Human | 3436 | |
| MAPK10 (JNK3) | MAPK | CMGC | 2exc | X | | n-{2'-[(4-fluorophenyl)amino]-4,4'-bipyridin-2-yl}-4-methoxycyclohexanecarboxamide | Human | 3478 | |
| MAPK10 (JNK3) | MAPK | CMGC | 8vnx | A | A | (4p)-4-[5-(2-chloro-6-fluoroanilino)-6-(methoxymethyl)-1h-indazol-1-yl]-n-methylthiophene-2-carboxamide | Human | 15638 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3rtp | A | | n-[4-cyano-3-(1h-1,2,4-triazol-5-yl)thiophen-2-yl]-2-(2-oxo-3,4-dihydroquinolin-1(2h)-yl)acetamide | Human | 3467 | |
| MAPK10 (JNK3) | MAPK | CMGC | 2waj | A | A | 1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline | Human | 3472 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4w4v | A | | 3-(4-{[(2-chlorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-n-(2-methylpyridin-4-yl)benzamide | Human | 3437 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3ttj | A | A | 9-cyclopentyl-n~8~-(2-fluorophenyl)-n~2~-(4-methoxyphenyl)-9h-purine-2,8-diamine | Human | 3458 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3v6r | B | B | 4-{[4-(dimethylamino)butanoyl]amino}-n-(3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide | Human | 3417 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4x21 | B | | n-ethyl-4-{[4-(1h-indol-3-yl)-5-iodopyrimidin-2-yl]amino}piperidine-1-carboxamide | Human | 6239 | |
| MAPK10 (JNK3) | MAPK | CMGC | 8wgf | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 15046 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4z9l | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 3438 | |
| MAPK10 (JNK3) | MAPK | CMGC | 6eq9 | B | B | phosphomethylphosphonic acid adenylate ester | Human | 10499 | |
| MAPK10 (JNK3) | MAPK | CMGC | 2p33 | A | | 4-{[5-chloro-4-(1h-indol-3-yl)pyrimidin-2-yl]amino}-n-ethylpiperidine-1-carboxamide | Human | 3455 | |
| MAPK10 (JNK3) | MAPK | CMGC | 7ksk | A | | 4-(4-{[(2-chlorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-n-(oxetan-3-yl)thiophene-2-carboxamide | Human | 13386 | |
| MAPK10 (JNK3) | MAPK | CMGC | 1pmv | A | | 2,6-dihydroanthra/1,9-cd/pyrazol-6-one | Human | 3434 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4h3b | C | C | - | Human | 3446 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4h3b | A | B | - | Human | 3454 | |
| MAPK10 (JNK3) | MAPK | CMGC | 8bzp | A | B | 2-bromanyl-2,2-bis(fluoranyl)-~{n}-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ethanamide | Human | 14858 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3tti | A | | trans-4-({9-[(3s)-tetrahydrofuran-3-yl]-8-[(2,4,6-trifluorophenyl)amino]-9h-purin-2-yl}amino)cyclohexanol | Human | 3456 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4whz | A | B | 3-(4-{[(2-chlorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-n-{1-[(3s)-pyrrolidin-3-yl]-1h-pyrazol-4-yl}benzamide | Human | 3422 | |
| MAPK10 (JNK3) | MAPK | CMGC | 6emh | B | A | 4-(4-methyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amine | Human | 10506 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3g9l | X | | (3z)-1-[(6-fluoro-4h-1,3-benzodioxin-8-yl)methyl]-4-[(e)-2-phenylethenyl]-1h-indole-2,3-dione 3-oxime | Human | 3435 | |
| MAPK10 (JNK3) | MAPK | CMGC | 8vnx | A | B | (4p)-4-[5-(2-chloro-6-fluoroanilino)-6-(methoxymethyl)-1h-indazol-1-yl]-n-methylthiophene-2-carboxamide | Human | 15639 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4h39 | A | B | - | Human | 3462 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3v6s | A | B | 3-{[4-(dimethylamino)butanoyl]amino}-n-(4-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide | Human | 3449 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3fi2 | A | B | 3-{4-[(phenylcarbamoyl)amino]-1h-pyrazol-1-yl}-n-(3,4,5-trimethoxyphenyl)benzamide | Human | 3452 | |
| MAPK10 (JNK3) | MAPK | CMGC | 6emh | D | A | 4-(4-methyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amine | Human | 10497 | |
| MAPK10 (JNK3) | MAPK | CMGC | 2zdu | A | | 4-[(4-{[6-bromo-3-(methoxycarbonyl)-1-oxo-4-phenylisoquinolin-2(1h)-yl]methyl}phenyl)amino]-4-oxobutanoic acid | Human | 3479 | |
| MAPK10 (JNK3) | MAPK | CMGC | 6emh | A | B | 4-(4-methyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amine | Human | 10503 | |
| MAPK10 (JNK3) | MAPK | CMGC | 2zdt | A | B | 4-[(6-chloro-1-oxo-4-phenyl-3-propanoylisoquinolin-2(1h)-yl)methyl]benzoic acid | Human | 3424 | |
| MAPK10 (JNK3) | MAPK | CMGC | 7orf | A | B | n-[4-[[4-[5-(4-fluorophenyl)-3-methyl-2-methylsulfanyl-imidazol-4-yl]pyridin-2-yl]amino]phenyl]-3-(propanoylamino)benzamide | Human | 13814 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4u79 | A | | n-{4-[(3-{2-[(trans-4-aminocyclohexyl)amino]pyrimidin-4-yl}pyridin-2-yl)oxy]naphthalen-1-yl}benzenesulfonamide | Human | 3466 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3v6s | B | B | 3-{[4-(dimethylamino)butanoyl]amino}-n-(4-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide | Human | 3425 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3kvx | A | A | n-[(2z)-4-(3-fluoro-5-morpholin-4-ylphenyl)pyrimidin-2(1h)-ylidene]-4-(3-morpholin-4-yl-1h-1,2,4-triazol-1-yl)aniline | Human | 3433 | |
| MAPK10 (JNK3) | MAPK | CMGC | 8enj | A | | n-[3-({(4p)-4-[(3m)-1-tert-butyl-3-(3-hydroxyphenyl)-1h-pyrazol-4-yl]pyridin-2-yl}amino)propyl]-4-hydroxybenzene-1-sulfonamide | Human | 14884 | |
| MAPK10 (JNK3) | MAPK | CMGC | 2zdt | A | A | 4-[(6-chloro-1-oxo-4-phenyl-3-propanoylisoquinolin-2(1h)-yl)methyl]benzoic acid | Human | 3421 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4h3b | C | B | - | Human | 3465 | |
| MAPK10 (JNK3) | MAPK | CMGC | 8bzp | A | A | 2-bromanyl-2,2-bis(fluoranyl)-~{n}-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ethanamide | Human | 14859 | |
| MAPK10 (JNK3) | MAPK | CMGC | 7yl1 | A | | 7-hexyl-3-methyl-8-sulfanylidene-9h-purine-2,6-dione | Human | 14845 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3v6r | A | A | 4-{[4-(dimethylamino)butanoyl]amino}-n-(3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide | Human | 3441 | |
| MAPK10 (JNK3) | MAPK | CMGC | 8wgf | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 15047 | |
| MAPK10 (JNK3) | MAPK | CMGC | 2o0u | A | | n-{3-cyano-6-[3-(1-piperidinyl)propanoyl]-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl}1-naphthalenecarboxamide | Human | 3415 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3fi3 | A | A | 3-{5-[(2-fluorophenyl)amino]-1h-indazol-1-yl}-n-(3,4,5-trimethoxyphenyl)benzamide | Human | 3442 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3fi3 | A | B | 3-{5-[(2-fluorophenyl)amino]-1h-indazol-1-yl}-n-(3,4,5-trimethoxyphenyl)benzamide | Human | 3445 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g97 | A | A | 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2-(2-methoxyethyl)-3~{h}-isoindol-1-one | Human | 9960 | |
| MAPK7 (Erk5) | MAPK | CMGC | 4b99 | A | | 11-cyclopentyl-2-[[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl-phenyl]amino]-5-methyl-pyrimido[4,5-b][1,4]benzodiazepin-6-one | Human | 388 | |
| MAPK8 (JNK1) | MAPK | CMGC | 8x5m | A | B | 3-[4-(dimethylamino)butanoylamino]-~{n}-[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide | Human | 15100 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv3 | A | A | ethyl n-{2-chloro-4-[5-(5-{[(1s)-1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl]carbamoyl}-1h-pyrrol-3-yl)-1h-pyrazol-4-yl]benzyl}glycinate | Human | 2617 | |
| MAPK14 (p38a) | MAPK | CMGC | 3oef | X | A | - | Human | 5163 | |
| MAPK14 (p38a) | MAPK | CMGC | 4e5a | X | B | - | Human | 5222 | |
| MAPK14 (p38a) | MAPK | CMGC | 6qdz | A | B | 1-[5-~{tert}-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[(1~{s},4~{s})-4-[(3-propan-2-yl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)oxy]-1,2,3,4-tetrahydronaphthalen-1-yl]urea | Human | 11958 | |
| MAPK14 (p38a) | MAPK | CMGC | 3zya | A | B | 2-amino-phenylamino-dibenzosuberone | Human | 5089 | |
| MAPK14 (p38a) | MAPK | CMGC | 4ewq | A | A | 3-phenyl-4-(pyridin-4-yl)-6-[4-(pyrimidin-2-yl)piperazin-1-yl]pyridazine | Human | 5200 | |
| MAPK14 (p38a) | MAPK | CMGC | 4kiq | B | | ethyl 6-{[5-(cyclopropylcarbamoyl)-2-methylphenyl]carbamoyl}-1h-indole-1-carboxylate | Human | 5013 | |
| MAPK14 (p38a) | MAPK | CMGC | 3zsi | A | B | 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6h-pyrimido[1,6-b]pyridazin-6-one | Human | 4983 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hp2 | A | B | 1-benzyl-4-(benzyloxy)-3-bromopyridin-2(1h)-one | Human | 5031 | |
| MAPK14 (p38a) | MAPK | CMGC | 3kq7 | A | A | n-(2-methyl-5-{[(2-morpholin-4-ylpyridin-4-yl)carbonyl]amino}phenyl)-6-({2-[(2s)-1-methylpyrrolidin-2-yl]ethyl}amino)pyridine-3-carboxamide | Human | 5081 | |
| MAPK14 (p38a) | MAPK | CMGC | 3uvq | A | B | n-{5-[(7-{[(2r)-2,3-dihydroxypropyl]oxy}-5-oxo-10,11-dihydro-5h-dibenzo[a,d][7]annulen-2-yl)amino]-2-fluorophenyl}benzamide | Human | 5214 | |
| MAPK14 (p38a) | MAPK | CMGC | 5omh | A | | 1-(3-chlorophenyl)-3-methyl-4~{h}-pyrazolo[4,3-c][1,2]benzothiazine 5,5-dioxide | Human | 11251 | |
| MAPK14 (p38a) | MAPK | CMGC | 4ehv | A | A | - | Human | 4997 | |
| MAPK14 (p38a) | MAPK | CMGC | 3mw1 | A | | 8-(2,6-dichlorophenyl)-4-(2,4-difluorophenyl)-2-piperidin-4-yl-1,7-naphthyridine 7-oxide | Human | 5072 | |
| MAPK14 (p38a) | MAPK | CMGC | 1zzl | A | | 6-[4-(4-fluorophenyl)-1,3-oxazol-5-yl]-3-isopropyl[1,2,4]triazolo[4,3-a]pyridine | Human | 5249 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gfe | A | | n-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1h-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide | Human | 4991 | |
| MAPK14 (p38a) | MAPK | CMGC | 1bmk | A | | 4-(fluorophenyl)-1-cyclopropylmethyl-5-(2-amino-4-pyrimidinyl)imidazole | Human | 5235 | |
| MAPK1 (Erk2) | MAPK | CMGC | 1tvo | A | | 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1h-pyrazolo[3,4-c]pyridazin-3-amine | Human | 2581 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fly | A | | 6-(2,4-difluorophenoxy)-8-methyl-2-[(1-methylethyl)amino]pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 5113 | |
| MAPK14 (p38a) | MAPK | CMGC | 3lff | A | B | (4-{3-tert-butyl-5-[(1,3-thiazol-2-ylcarbamoyl)amino]-1h-pyrazol-1-yl}phenyl)acetic acid | Human | 5120 | |
| MAPK14 (p38a) | MAPK | CMGC | 3lfe | A | | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-{4-[2-(pyridin-4-ylmethoxy)ethyl]-1,3-thiazol-2-yl}urea | Human | 5173 | |
| MAPK14 (p38a) | MAPK | CMGC | 6qdz | A | A | 1-[5-~{tert}-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[(1~{s},4~{s})-4-[(3-propan-2-yl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)oxy]-1,2,3,4-tetrahydronaphthalen-1-yl]urea | Human | 11956 | |
| MAPK14 (p38a) | MAPK | CMGC | 4eh8 | A | A | [3-(benzyloxy)phenyl]methanol | Human | 4978 | |
| MAPK14 (p38a) | MAPK | CMGC | 2lgc | A | 8 | - | Human | 5078 | |
| MAPK14 (p38a) | MAPK | CMGC | 3lfa | A | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 5018 | |
| MAPK14 (p38a) | MAPK | CMGC | 2onl | B | | - | Human | 5007 | |
| MAPK14 (p38a) | MAPK | CMGC | 4aa0 | A | B | n-[4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxidanylidene-quinazolin-3-yl]phenyl]-2-morpholin-4-yl-pyridine-4-carboxamide | Human | 5132 | |
| MAPK14 (p38a) | MAPK | CMGC | 3mh1 | A | | - | Human | 5003 | |
| MAPK14 (p38a) | MAPK | CMGC | 3mpt | A | B | n-(furan-2-ylmethyl)-4-[(2-methylphenyl)carbonyl]-1h-pyrrole-2-carboxamide | Human | 5246 | |
| MAPK14 (p38a) | MAPK | CMGC | 5xyy | A | | 3-(5-{[(2-chloro-6-fluorophenyl)methyl]amino}-4h-1,2,4-triazol-3-yl)phenol | Human | 9513 | |
| MAPK14 (p38a) | MAPK | CMGC | 3d7z | A | A | n~3~-cyclopropyl-n~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide | Human | 5247 | |
| MAPK14 (p38a) | MAPK | CMGC | 3nww | A | | 1-[2-(2-{[2-(dimethylamino)ethyl]amino}-6-{2-[(1-methylethyl)amino]-1,3-thiazol-5-yl}pyrimidin-4-yl)benzyl]-3-ethylurea | Human | 5068 | |
| MAPK14 (p38a) | MAPK | CMGC | 5wjj | A | B | n-{4-[2-(4-fluoro-3-methylphenyl)imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl}-2-methyl-1-oxo-1lambda~5~-pyridine-4-carboxamide | Human | 9516 | |
| MAPK14 (p38a) | MAPK | CMGC | 2okr | A | | - | Human | 5136 | |
| MAPK14 (p38a) | MAPK | CMGC | 3kf7 | A | | 3-{6-[2-(2,4-difluorophenyl)ethyl][1,2,4]triazolo[4,3-a]pyridin-3-yl}-4-methylbenzamide | Human | 5201 | |
| MAPK14 (p38a) | MAPK | CMGC | 3huc | A | B | n-[2-phenyl-4-(1h-pyrazol-3-ylamino)quinazolin-7-yl]prop-2-enamide | Human | 5111 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gc7 | A | B | 5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-[1-(1-methylethyl)piperidin-4-yl]-3,4-dihydroquinazolin-2(1h)-one | Human | 5256 | |
| MAPK14 (p38a) | MAPK | CMGC | 6zwp | A | B | 5-azanyl-~{n}-[[4-[[(2~{s})-4-cyclohexyl-1-[(4-fluorophenyl)amino]-1-oxidanylidene-butan-2-yl]carbamoyl]phenyl]methyl]-1-phenyl-pyrazole-4-carboxamide | Human | 12698 | |
| MAPK14 (p38a) | MAPK | CMGC | 1oz1 | A | A | 3-(4-fluorophenyl)-2-pyridin-4-yl-1h-pyrrolo[3,2-b]pyridin-1-ol | Human | 5230 | |
| MAPK14 (p38a) | MAPK | CMGC | 2baq | A | | [5-amino-1-(4-fluorophenyl)-1h-pyrazol-4-yl](3-{[(2r)-2,3-dihydroxypropyl]oxy}phenyl)methanone | Human | 5184 | |
| MAPK14 (p38a) | MAPK | CMGC | 3uvp | A | B | n-{2-fluoro-5-[(5-oxo-6,7,8,9-tetrahydro-5h-benzo[7]annulen-2-yl)amino]phenyl}benzamide | Human | 5155 | |
| MAPK14 (p38a) | MAPK | CMGC | 3mgy | A | | - | Human | 5171 | |
| MAPK14 (p38a) | MAPK | CMGC | 3lfb | A | A | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-(1,3-thiazol-2-yl)urea | Human | 4998 | |
| MAPK14 (p38a) | MAPK | CMGC | 3nnv | A | B | 1-{3-tert-butyl-1-[4-(hydroxymethyl)phenyl]-1h-pyrazol-5-yl}-3-naphthalen-1-ylurea | Human | 5046 | |
| MAPK14 (p38a) | MAPK | CMGC | 3zs5 | A | B | 4-[5-(4-fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-3h-imidazol-4-yl]-pyridine | Human | 4977 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hv3 | A | A | 1-{4-[(6-aminoquinolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(3-methylphenyl)-1h-pyrazol-5-yl]urea | Human | 5012 | |
| MAPK14 (p38a) | MAPK | CMGC | 3mvm | A | | 4-{[5-(isoxazol-3-ylcarbamoyl)-2-methylphenyl]amino}-5-methyl-n-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide | Human | 4993 | |
| MAPK14 (p38a) | MAPK | CMGC | 4kin | A | | 5-(2-chlorophenyl)-n-[5-(cyclopropylcarbamoyl)-2-methylphenyl]thiophene-2-carboxamide | Human | 5237 | |
| MAPK14 (p38a) | MAPK | CMGC | 6zqs | A | | 2-[(2,4-difluorophenyl)amino]-7-{[(2r)-2,3-dihydroxypropyl]oxy}-10,11-dihydro-5h-dibenzo[a,d][7]annulen-5-one | Human | 12986 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fmm | A | | 6-(2,4-difluorophenoxy)-n-[(1r)-1-methyl-2-(methylsulfonyl)ethyl]-1h-pyrazolo[3,4-d]pyrimidin-3-amine | Human | 5186 | |
| MAPK14 (p38a) | MAPK | CMGC | 4kin | D | | 5-(2-chlorophenyl)-n-[5-(cyclopropylcarbamoyl)-2-methylphenyl]thiophene-2-carboxamide | Human | 5144 | |
| MAPK14 (p38a) | MAPK | CMGC | 6sfk | A | A | ~{n}-[5-[[(2~{s})-1-azanyl-4-cyclohexyl-1-oxidanylidene-butan-2-yl]carbamoyl]-2-methyl-phenyl]-1-phenyl-5-(trifluoromethyl)pyrazole-4-carboxamide | Human | 11617 | |
| MAPK14 (p38a) | MAPK | CMGC | 3odz | X | | - | Human | 5069 | |
| MAPK14 (p38a) | MAPK | CMGC | 4fa2 | A | A | trans-4-[4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)-1h-imidazol-1-yl]cyclohexanol | Human | 5150 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fc1 | X | | 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6h-pyrimido[1,6-b]pyridazin-6-one | Human | 5110 | |
| MAPK14 (p38a) | MAPK | CMGC | 3e92 | A | | n-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide | Human | 5149 | |
| MAPK14 (p38a) | MAPK | CMGC | 8yd9 | A | B | - | Human | 15696 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hv4 | B | | 1-{3-[(6-aminoquinolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]urea | Human | 5064 | |
| MAPK14 (p38a) | MAPK | CMGC | 9r27 | A | | 4-[4-[[4-chloranyl-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluoranyl-phenoxy]-~{n}-methyl-pyridine-2-carboxamide | Human | 15697 | |
| MAPK14 (p38a) | MAPK | CMGC | 1wbn | A | | n-(3-tert-butyl-1h-pyrazol-5-yl)-n'-{4-chloro-3-[(pyridin-3-yloxy)methyl]phenyl}urea | Human | 5257 | |
| MAPK14 (p38a) | MAPK | CMGC | 3roc | A | | 3-{5-chloro-4-[(2,4-difluorobenzyl)oxy]-6-oxopyrimidin-1(6h)-yl}-n-(2-hydroxyethyl)-4-methylbenzamide | Human | 5011 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gcp | A | A | 4-[5-(4-fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-3h-imidazol-4-yl]-pyridine | Human | 5194 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hv6 | A | | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-[4-(2-morpholin-4-ylethoxy)phenyl]urea | Human | 5101 | |
| MAPK14 (p38a) | MAPK | CMGC | 2yiw | A | | 1-(3-tert-butyl-1-phenyl-1h-pyrazol-5-yl)-3-(2-{[3-(1-methylethyl)[1,2,4]triazolo[4,3-a]pyridin-6-yl]sulfanyl}benzyl)urea | Human | 4988 | |
| MAPK14 (p38a) | MAPK | CMGC | 4e6c | A | | - | Human | 5015 | |
| MAPK14 (p38a) | MAPK | CMGC | 1di9 | A | | 4-[3-methylsulfanylanilino]-6,7-dimethoxyquinazoline | Human | 5251 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gcq | A | B | 1-{4-[(6-aminoquinazolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(3-methylphenyl)-1h-pyrazol-5-yl]urea | Human | 5053 | |
| MAPK14 (p38a) | MAPK | CMGC | 2lgc | A | 5 | - | Human | 5107 | |
| MAPK14 (p38a) | MAPK | CMGC | 3l8x | A | | n,4-dimethyl-3-[(1-phenyl-1h-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide | Human | 5041 | |
| MAPK14 (p38a) | MAPK | CMGC | 8a8m | A | | phosphomethylphosphonic acid adenosyl ester | Human | 14289 | |
| MAPK14 (p38a) | MAPK | CMGC | 5etc | A | | - | Human | 6361 | |
| MAPK14 (p38a) | MAPK | CMGC | 1wfc | A | | - | Human | 4989 | |
| MAPK14 (p38a) | MAPK | CMGC | 3e93 | A | B | 4-methyl-n-(3-morpholin-4-ylphenyl)-3-(3-piperidin-4-yl-1,2-benzisoxazol-6-yl)benzamide | Human | 5004 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gcu | B | A | 1-{3-[(6-aminoquinazolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]urea | Human | 5175 | |
| MAPK14 (p38a) | MAPK | CMGC | 1yqj | A | | 6((s)-3-benzylpiperazin-1-yl)-3-(naphthalen-2-yl)-4-(pyridin-4-yl)pyrazine | Human | 5152 | |
| MAPK14 (p38a) | MAPK | CMGC | 9cj5 | A | | pexmetinib | Human | 15698 | |
| MAPK14 (p38a) | MAPK | CMGC | 5o8u | A | | - | Human | 8381 | |
| MAPK14 (p38a) | MAPK | CMGC | 4e8a | A | | - | Human | 4979 | |
| MAPK14 (p38a) | MAPK | CMGC | 3mpa | A | | 4-[5-(4-fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-3h-imidazol-4-yl]-pyridine | Human | 5026 | |
| MAPK14 (p38a) | MAPK | CMGC | 6tca | H | B | n-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1h-pyrazole-4-carboxamide | Human | 12487 | |
| MAPK14 (p38a) | MAPK | CMGC | 2npq | A | | - | Human | 5205 | |
| MAPK14 (p38a) | MAPK | CMGC | 5xyx | A | B | n-(2-chloro-6-fluorobenzyl)-5-(furan-2-yl)-2h-1,2,4-triazol-3-amine | Human | 9517 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gcu | A | A | 1-{3-[(6-aminoquinazolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]urea | Human | 5032 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hvc | A | | 4-[3-(4-fluorophenyl)-1h-pyrazol-4-yl]pyridine | Human | 5054 | |
| MAPK14 (p38a) | MAPK | CMGC | 4a9y | A | | n-(3-{[7-methoxy-6-(2-pyrrolidin-1-ylethoxy)quinazolin-4-yl]amino}-4-methylphenyl)-2-morpholin-4-ylisonicotinamide | Human | 5073 | |
| MAPK14 (p38a) | MAPK | CMGC | 4r3c | A | B | 6-(4-methylpiperazin-1-yl)-3-(naphthalen-2-yl)-4-(pyridin-4-yl)pyridazine | Human | 5036 | |
| MAPK14 (p38a) | MAPK | CMGC | 1wbw | A | | 3-(1-naphthylmethoxy)pyridin-2-amine | Human | 5179 | |
| MAPK14 (p38a) | MAPK | CMGC | 4eh7 | A | A | (3-phenoxyphenyl)methanol | Human | 5208 | |
| MAPK14 (p38a) | MAPK | CMGC | 3ody | X | | - | Human | 5233 | |
| MAPK14 (p38a) | MAPK | CMGC | 1wbo | A | | 2-chlorophenol | Human | 5039 | |
| MAPK14 (p38a) | MAPK | CMGC | 8yd9 | A | A | - | Human | 15699 | |
| MAPK14 (p38a) | MAPK | CMGC | 3d83 | A | | n-{4'-[(cyclopropylmethyl)carbamoyl]-6-methylbiphenyl-3-yl}-2-morpholin-4-ylpyridine-4-carboxamide | Human | 5028 | |
| MAPK14 (p38a) | MAPK | CMGC | 6anl | A | A | tak-715 | Human | 9515 | |
| MAPK14 (p38a) | MAPK | CMGC | 3mvl | A | | 4-{[5-(cyclopropylcarbamoyl)-2-methylphenyl]amino}-5-methyl-n-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide | Human | 5060 | |
| MAPK14 (p38a) | MAPK | CMGC | 2lgc | A | 3 | - | Human | 5040 | |
| MAPK14 (p38a) | MAPK | CMGC | 4e5a | X | A | - | Human | 5189 | |
| MAPK14 (p38a) | MAPK | CMGC | 3iw5 | A | | n-[2-(3-{[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxoethyl]sulfanyl}-1h-indol-1-yl)ethyl]-3-(trifluoromethyl)benzamide | Human | 5076 | |
| MAPK14 (p38a) | MAPK | CMGC | 4kin | C | | 5-(2-chlorophenyl)-n-[5-(cyclopropylcarbamoyl)-2-methylphenyl]thiophene-2-carboxamide | Human | 5142 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fsk | A | | 3-(2-chlorophenyl)-7-[(trans-4-hydroxycyclohexyl)amino]-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 5008 | |
| MAPK14 (p38a) | MAPK | CMGC | 1ove | A | C | 1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-piperidin-4-yl-3,4-dihydroquinolin-2(1h)-one | Human | 5199 | |
| MAPK14 (p38a) | MAPK | CMGC | 6zwp | A | A | 5-azanyl-~{n}-[[4-[[(2~{s})-4-cyclohexyl-1-[(4-fluorophenyl)amino]-1-oxidanylidene-butan-2-yl]carbamoyl]phenyl]methyl]-1-phenyl-pyrazole-4-carboxamide | Human | 12699 | |
| MAPK14 (p38a) | MAPK | CMGC | 3lhj | A | | n-cyclopropyl-3-[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1h-pyrazolo[3,4-b]pyridin-5-yl]-4-methylbenzamide | Human | 5234 | |
| MAPK14 (p38a) | MAPK | CMGC | 4kip | B | | 2-(2-chlorophenyl)-n-[5-(cyclopropylcarbamoyl)-2-methylphenyl]-1,3-thiazole-5-carboxamide | Human | 5180 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fl4 | A | | 6-(2,4-difluorophenoxy)-3-(2-methylphenyl)-1h-pyrazolo[3,4-d]pyrimidine | Human | 5151 | |
| MAPK14 (p38a) | MAPK | CMGC | 3s4q | A | | 3-[(6-benzoyl-5-methylpyrrolo[2,1-f][1,2,4]triazin-4-yl)amino]-n-cyclopropyl-4-methylbenzamide | Human | 5133 | |
| MAPK14 (p38a) | MAPK | CMGC | 2zaz | A | B | 4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehyde | Human | 5034 | |
| MAPK14 (p38a) | MAPK | CMGC | 3lfc | A | | (4-{5-[({4-[2-(benzyloxy)ethyl]-1,3-thiazol-2-yl}carbamoyl)amino]-3-tert-butyl-1h-pyrazol-1-yl}phenyl)acetic acid | Human | 5160 | |
| MAPK14 (p38a) | MAPK | CMGC | 2zb1 | A | A | n-(cyclopropylmethyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide | Human | 5038 | |
| MAPK14 (p38a) | MAPK | CMGC | 4f9y | A | B | n,n-dimethyl-6-(naphthalen-1-yl)-5-(pyridin-4-yl)pyridazin-3-amine | Human | 5017 | |
| MAPK14 (p38a) | MAPK | CMGC | 3ocg | A | | 5-amino-n-[5-(isoxazol-3-ylcarbamoyl)-2-methylphenyl]-1-phenyl-1h-pyrazole-4-carboxamide | Human | 4984 | |
| MAPK14 (p38a) | MAPK | CMGC | 2bal | A | | [5-amino-1-(4-fluorophenyl)-1h-pyrazol-4-yl][3-(piperidin-4-yloxy)phenyl]methanone | Human | 5260 | |
| MAPK14 (p38a) | MAPK | CMGC | 5eta | B | | - | Human | 7137 | |
| MAPK14 (p38a) | MAPK | CMGC | 2fst | X | B | - | Human | 5195 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hv3 | A | B | 1-{4-[(6-aminoquinolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(3-methylphenyl)-1h-pyrazol-5-yl]urea | Human | 5232 | |
| MAPK14 (p38a) | MAPK | CMGC | 4aa0 | A | A | n-[4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxidanylidene-quinazolin-3-yl]phenyl]-2-morpholin-4-yl-pyridine-4-carboxamide | Human | 5213 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fln | C | | 6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2h-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 5090 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hv5 | B | B | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-{3-[(6-nitroquinolin-4-yl)amino]phenyl}urea | Human | 5137 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gi3 | A | | n-{5-tert-butyl-2-methoxy-3-[({4-[6-(morpholin-4-ylmethyl)pyridin-3-yl]naphthalen-1-yl}carbamoyl)amino]phenyl}methanesulfonamide | Human | 5226 | |
| MAPK14 (p38a) | MAPK | CMGC | 6sfi | A | B | ~{n}-[(2~{s})-1-azanyl-4-cyclohexyl-1-oxidanylidene-butan-2-yl]-2-[[[1-(2-methylphenyl)pyrazol-4-yl]carbonylamino]methyl]-1,3-thiazole-5-carboxamide | Human | 11619 | |
| MAPK14 (p38a) | MAPK | CMGC | 6tca | F | A | n-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1h-pyrazole-4-carboxamide | Human | 12489 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hp2 | A | A | 1-benzyl-4-(benzyloxy)-3-bromopyridin-2(1h)-one | Human | 5217 | |
| MAPK14 (p38a) | MAPK | CMGC | 5mtx | A | A | 3-[(3-benzamido-4-fluoranyl-phenyl)amino]-~{n}-(2-morpholin-4-ylethyl)-11-oxidanylidene-6~{h}-benzo[c][1]benzoxepine-9-carboxamide | Human | 8382 | |
| MAPK14 (p38a) | MAPK | CMGC | 3nnx | A | | 2-[3-(3-tert-butyl-5-{[(2,3-dichlorophenyl)carbamoyl]imino}-2,5-dihydro-1h-pyrazol-1-yl)phenyl]acetamide | Human | 5002 | |
| MAPK14 (p38a) | MAPK | CMGC | 3ds6 | B | | n-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide | Human | 5188 | |
| MAPK14 (p38a) | MAPK | CMGC | 4l8m | A | A | n-[2-fluoro-5-({9-[2-(morpholin-4-yl)ethoxy]-11-oxo-6,11-dihydrodibenzo[b,e]oxepin-3-yl}amino)phenyl]benzamide | Human | 5005 | |
| MAPK14 (p38a) | MAPK | CMGC | 2bak | A | | n-(3-{[7-methoxy-6-(2-pyrrolidin-1-ylethoxy)quinazolin-4-yl]amino}-4-methylphenyl)-2-morpholin-4-ylisonicotinamide | Human | 5114 | |
| MAPK14 (p38a) | MAPK | CMGC | 2fsm | X | | - | Human | 5044 | |
| MAPK14 (p38a) | MAPK | CMGC | 9cj2 | A | A | - | Human | 15700 | |
| MAPK14 (p38a) | MAPK | CMGC | 3zsh | A | A | 2-(6-chloro-5-{[(2r,5s)-4-(4-fluorobenzyl)-2,5-dimethylpiperazin-1-yl]carbonyl}-1-methyl-1h-indol-3-yl)-n,n-dimethyl-2-oxoacetamide | Human | 5216 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hv5 | A | B | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-{3-[(6-nitroquinolin-4-yl)amino]phenyl}urea | Human | 5263 | |
| MAPK14 (p38a) | MAPK | CMGC | 1ouk | A | | 4-[5-[2-(1-phenyl-ethylamino)-pyrimidin-4-yl]-1-methyl-4-(3-trifluoromethylphenyl)-1h-imidazol-2-yl]-piperidine | Human | 5146 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hl7 | A | | 2-{4-[5-(4-chlorophenyl)-4-pyrimidin-4-yl-1h-pyrazol-3-yl]piperidin-1-yl}-2-oxoethanol | Human | 5236 | |
| MAPK14 (p38a) | MAPK | CMGC | 6ohd | A | B | 3-(3-tert-butyl-2-oxo-2,3-dihydro-1h-imidazo[4,5-b]pyridin-6-yl)-4-methyl-n-(1,2-oxazol-3-yl)benzamide | Human | 11819 | |
| MAPK14 (p38a) | MAPK | CMGC | 4kip | A | | 2-(2-chlorophenyl)-n-[5-(cyclopropylcarbamoyl)-2-methylphenyl]-1,3-thiazole-5-carboxamide | Human | 5159 | |
| MAPK14 (p38a) | MAPK | CMGC | 3ds6 | C | | n-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide | Human | 5182 | |
| MAPK14 (p38a) | MAPK | CMGC | 2lgc | A | 9 | - | Human | 5127 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hll | A | A | 3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1(2h)-yl}-n,4-dimethylbenzamide | Human | 5115 | |
| MAPK14 (p38a) | MAPK | CMGC | 4l8m | A | B | n-[2-fluoro-5-({9-[2-(morpholin-4-yl)ethoxy]-11-oxo-6,11-dihydrodibenzo[b,e]oxepin-3-yl}amino)phenyl]benzamide | Human | 4992 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fml | A | | 6-(2,4-difluorophenoxy)-n-[(1s)-1-methyl-2-(methylsulfonyl)ethyl]-1h-pyrazolo[3,4-d]pyrimidin-3-amine | Human | 5010 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fmj | A | | 4-(5-methyl-3-phenylisoxazol-4-yl)pyrimidin-2-amine | Human | 5129 | |
| MAPK14 (p38a) | MAPK | CMGC | 6m9l | A | | 3-benzyl-6-[(2,4-difluorophenyl)amino]-1,3-dihydro-2h-imidazo[4,5-b]pyridin-2-one | Human | 11255 | |
| MAPK14 (p38a) | MAPK | CMGC | 2y8o | A | B | - | Human | 5030 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fmn | A | B | 6-(2,4-difluorophenoxy)-n-(tetrahydro-2h-pyran-4-yl)-1h-pyrazolo[3,4-d]pyrimidin-3-amine | Human | 4995 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hp5 | A | | 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6h-pyrimido[1,6-b]pyridazin-6-one | Human | 5158 | |
| MAPK14 (p38a) | MAPK | CMGC | 3heg | A | B | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 5218 | |
| MAPK14 (p38a) | MAPK | CMGC | 9cj4 | A | C | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 15706 | |
| MAPK14 (p38a) | MAPK | CMGC | 4kin | B | | 5-(2-chlorophenyl)-n-[5-(cyclopropylcarbamoyl)-2-methylphenyl]thiophene-2-carboxamide | Human | 5131 | |
| MAPK14 (p38a) | MAPK | CMGC | 1kv2 | A | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 5255 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fmh | A | | 6-(2,4-difluorophenoxy)-8-methyl-2-{[(1r)-1-methyl-2-(2h-tetrazol-2-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 5024 | |
| MAPK14 (p38a) | MAPK | CMGC | 3flw | A | | 6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxyethyl)propyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 5153 | |
| MAPK14 (p38a) | MAPK | CMGC | 4kiq | D | | ethyl 6-{[5-(cyclopropylcarbamoyl)-2-methylphenyl]carbamoyl}-1h-indole-1-carboxylate | Human | 5016 | |
| MAPK14 (p38a) | MAPK | CMGC | 4ehv | A | B | - | Human | 4981 | |
| MAPK14 (p38a) | MAPK | CMGC | 3mh0 | A | | - | Human | 5124 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hec | A | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 5035 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6qa1 | A | A | pyridin-2-amine | Human | 11352 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5nho | A | | (6~{s})-5-(2-methoxyethyl)-6-methyl-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydro-1~{h}-pyrrolo[3,2-c]pyridin-4-one | Human | 7993 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4h3p | D | | phosphoaminophosphonic acid-adenylate ester | Human | 2575 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bvd | A | A | 2-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-7-[2-(tetrahydro-2h-pyran-4-ylamino)pyrimidin-4-yl]-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2h)-one | Human | 6030 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7nr3 | A | B | 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2-[2-oxidanylidene-2-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]-3~{h}-isoindol-1-one | Human | 13922 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7nqw | A | A | 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2-[2-oxidanylidene-2-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)ethyl]-3~{h}-isoindol-1-one | Human | 13927 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7nqq | A | B | 2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{s})-1-(hydroxymethyl)-2,3-dihydroinden-1-yl]ethanamide | Human | 13928 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7nr8 | A | B | (2~{r})-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{s})-1-[6-(4-methylpiperazin-1-yl)pyridin-2-yl]-2-oxidanyl-ethyl]propanamide | Human | 13929 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7w5o | A | | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 14110 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7auv | A | B | (2~{r})-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{s})-1-(3-fluoranyl-5-methoxy-phenyl)-2-oxidanyl-ethyl]propanamide | Human | 13930 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7nr9 | A | B | (2~{r})-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{s})-1-(2-methoxypyridin-4-yl)-2-oxidanyl-ethyl]propanamide | Human | 13931 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qp7 | B | | 2-(1h-pyrazol-4-yl)-5h-pyrrolo[2,3-b]pyrazine | Human | 6093 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g9a | A | B | 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2-(2-morpholin-4-ylethyl)-3~{h}-isoindol-1-one | Human | 11412 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4nif | E | B | phosphoaminophosphonic acid-adenylate ester | Human | 2591 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7auv | A | A | (2~{r})-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{s})-1-(3-fluoranyl-5-methoxy-phenyl)-2-oxidanyl-ethyl]propanamide | Human | 13925 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3fi2 | A | A | 3-{4-[(phenylcarbamoyl)amino]-1h-pyrazol-1-yl}-n-(3,4,5-trimethoxyphenyl)benzamide | Human | 3463 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4h3b | A | C | - | Human | 3453 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3fv8 | A | A | 5-bromo-n-(3-chloro-2-(4-(prop-2-ynyl)piperazin-1-yl)phenyl)furan-2-carboxamide | Human | 3468 | |
| MAPK10 (JNK3) | MAPK | CMGC | 6emh | C | A | 4-(4-methyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amine | Human | 10507 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3kvx | A | B | n-[(2z)-4-(3-fluoro-5-morpholin-4-ylphenyl)pyrimidin-2(1h)-ylidene]-4-(3-morpholin-4-yl-1h-1,2,4-triazol-1-yl)aniline | Human | 3430 | |
| MAPK8 (JNK1) | MAPK | CMGC | 3pze | A | | 3-(carbamoylamino)-5-phenylthiophene-2-carboxamide | Human | 4642 | |
| MAPK13 (p38d) | MAPK | CMGC | 4yno | A | | - | Human | 2947 | |
| MAPK8 (JNK1) | MAPK | CMGC | 8pt9 | A | | methyl (1s,3s)-1-methyl-3-[[3-[[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]carbamoyl]-4-oxidanylidene-cyclohexane-1-carboxylate | Human | 15293 | |
| MAPK8 (JNK1) | MAPK | CMGC | 8pta | A | | methyl (1r,3s)-1-methyl-3-[[3-[[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]carbamoyl]-4-oxidanylidene-cyclohexane-1-carboxylate | Human | 15294 | |
| MAPK8 (JNK1) | MAPK | CMGC | 8pt8 | A | | methyl (1r,3r)-1-methyl-3-[[3-[[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]methylcarbamoyl]-4-oxidanylidene-cyclohexane-1-carboxylate | Human | 15295 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8psw | A | B | amp phosphoramidate | Human | 15303 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8pt3 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 15304 | |
| MAPK10 (JNK3) | MAPK | CMGC | 1pmn | A | | cyclopropyl-{4-[5-(3,4-dichlorophenyl)-2-[(1-methyl)-piperidin]-4-yl-3-propyl-3h-imidazol-4-yl]-pyrimidin-2-yl}amine | Human | 3439 | |
| MAPK10 (JNK3) | MAPK | CMGC | 2ok1 | A | A | n-benzyl-4-[4-(3-chlorophenyl)-1h-pyrazol-3-yl]-1h-pyrrole-2-carboxamide | Human | 3444 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qte | A | B | 4-{2-[(2-chloro-4-fluorophenyl)amino]-5-methylpyrimidin-4-yl}-n-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-1h-pyrrole-2-carboxamide | Human | 2564 | |
| MAPK8 (JNK1) | MAPK | CMGC | 5lw1 | B | | adenosine | Human | 9081 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4yr8 | A | A | - | Human | 6452 | |
| MAPK9 (JNK2) | MAPK | CMGC | 7cml | B | A | - | Human | 12706 | |
| MAPK6 (Erk3) | MAPK | CMGC | 6ylc | A | | 5-fluoranyl-2-[5-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]benzenecarbonitrile | Human | 12791 | |
| MAPK6 (Erk3) | MAPK | CMGC | 6yky | B | A | 3-(4-methoxyphenyl)-~{n}-[(3~{r})-1-pyridin-4-ylpyrrolidin-3-yl]-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine | Human | 12792 | |
| MAPK6 (Erk3) | MAPK | CMGC | 6yll | A | | ~{n}4-[3-(4-methoxyphenyl)-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl]cyclohexane-1,4-diamine | Human | 12793 | |
| MAPK6 (Erk3) | MAPK | CMGC | 7aqb | A | A | - | Human | 12982 | |
| MAPK6 (Erk3) | MAPK | CMGC | 6ylc | D | | 5-fluoranyl-2-[5-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]benzenecarbonitrile | Human | 12795 | |
| MAPK6 (Erk3) | MAPK | CMGC | 7aqb | B | B | - | Human | 12983 | |
| MAPK6 (Erk3) | MAPK | CMGC | 6yky | D | A | 3-(4-methoxyphenyl)-~{n}-[(3~{r})-1-pyridin-4-ylpyrrolidin-3-yl]-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine | Human | 12796 | |
| MAPK6 (Erk3) | MAPK | CMGC | 6ylc | B | | 5-fluoranyl-2-[5-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]benzenecarbonitrile | Human | 12797 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4w4x | A | | 3-(4-{[(4-fluorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-n-(2-methylpyridin-4-yl)benzamide | Human | 3440 | |
| MAPK14 (p38a) | MAPK | CMGC | 5n67 | A | A | - | Human | 8523 | |
| MAPK14 (p38a) | MAPK | CMGC | 1r3c | A | A | - | Human | 5170 | |
| MAPK13 (p38d) | MAPK | CMGC | 8x23 | A | B | - | Human | 15128 | |
| MAPK7 (Erk5) | MAPK | CMGC | 5byz | A | B | 4-({5-fluoro-4-[2-methyl-1-(propan-2-yl)-1h-imidazol-5-yl]pyrimidin-2-yl}amino)-n-[2-(piperidin-1-yl)ethyl]benzamide | Human | 6592 | |
| MAPK7 (Erk5) | MAPK | CMGC | 4zsg | A | A | 3-amino-5-[(4-chlorophenyl)amino]-n-(propan-2-yl)-1h-1,2,4-triazole-1-carboxamide | Human | 6589 | |
| MAPK7 (Erk5) | MAPK | CMGC | 5byz | A | A | 4-({5-fluoro-4-[2-methyl-1-(propan-2-yl)-1h-imidazol-5-yl]pyrimidin-2-yl}amino)-n-[2-(piperidin-1-yl)ethyl]benzamide | Human | 6590 | |
| MAPK7 (Erk5) | MAPK | CMGC | 4zsj | A | A | 3-amino-5-[(4-chloro-3-methylphenyl)amino]-n-(propan-2-yl)-1h-1,2,4-triazole-1-carboxamide | Human | 6588 | |
| MAPK7 (Erk5) | MAPK | CMGC | 4ic8 | B | | - | Human | 389 | |
| MAPK7 (Erk5) | MAPK | CMGC | 4ic8 | A | | - | Human | 390 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4ux9 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 4643 | |
| MAPK8 (JNK1) | MAPK | CMGC | 2gmx | A | | n-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-bromo-2,5-dimethoxyphenyl)acetamide | Human | 4674 | |
| MAPK8 (JNK1) | MAPK | CMGC | 9ft9 | A | | phosphoaminophosphonic acid-adenylate ester | Human | 15532 | |
| MAPK8 (JNK1) | MAPK | CMGC | 3vuh | A | | - | Human | 4663 | |
| MAPK8 (JNK1) | MAPK | CMGC | 2g01 | B | | 6-chloro-9-hydroxy-1,3-dimethyl-1,9-dihydro-4h-pyrazolo[3,4-b]quinolin-4-one | Human | 4641 | |
| MAPK8 (JNK1) | MAPK | CMGC | 12cv | A | A | (4m)-n-[3-(dimethylcarbamoyl)-4-hydroxyphenyl]-4-(1h-pyrrolo[2,3-b]pyridin-5-yl)-3h-1lambda~4~-benzothiophene-2-carboxamide | Human | 15533 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4qtd | A | B | (3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamide | Human | 4673 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4hyu | A | | trans-4-[(4-{4-[3-(methylsulfonyl)propoxy]-1h-indazol-1-yl}pyrimidin-2-yl)amino]cyclohexanol | Human | 4632 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4l7f | A | A | n-[1-(4-fluorophenyl)cyclopropyl]-4-[(trans-4-hydroxycyclohexyl)amino]imidazo[1,2-a]quinoxaline-8-carboxamide | Human | 4639 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4e73 | A | A | methyl 3-(4-{[(1r,2s,3s,5s,7s)-5-aminotricyclo[3.3.1.1~3,7~]dec-2-yl]carbamoyl}benzyl)-4-oxo-1-phenyl-1,4-dihydro-1,8-naphthyridine-2-carboxylate | Human | 4645 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4ux9 | B | A | phosphoaminophosphonic acid-adenylate ester | Human | 4635 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4izy | A | | trans-4-[(4-{4-[4-(methylsulfonyl)piperidin-1-yl]-1h-indol-1-yl}pyrimidin-2-yl)amino]cyclohexanol | Human | 4654 | |
| MAPK8 (JNK1) | MAPK | CMGC | 11zl | A | B | (4m)-n-[4-hydroxy-3-(pyrrolidine-1-carbonyl)phenyl]-4-(1h-pyrrolo[2,3-b]pyridin-5-yl)-1-benzothiophene-2-carboxamide | Human | 15535 | |
| MAPK8 (JNK1) | MAPK | CMGC | 4yr8 | F | A | - | Human | 6450 | |
| MAPK8 (JNK1) | MAPK | CMGC | 2xrw | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 4650 | |
| MAPK8 (JNK1) | MAPK | CMGC | 12cv | A | B | (4m)-n-[3-(dimethylcarbamoyl)-4-hydroxyphenyl]-4-(1h-pyrrolo[2,3-b]pyridin-5-yl)-3h-1lambda~4~-benzothiophene-2-carboxamide | Human | 15536 | |
| MAPK8 (JNK1) | MAPK | CMGC | 3vum | A | | - | Human | 4671 | |
| MAPK8 (JNK1) | MAPK | CMGC | 3elj | A | A | 2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7h-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide | Human | 4658 | |
| MAPK8 (JNK1) | MAPK | CMGC | 3elj | A | B | 2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7h-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide | Human | 4636 | |
| MAPK8 (JNK1) | MAPK | CMGC | 8x5m | A | A | 3-[4-(dimethylamino)butanoylamino]-~{n}-[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide | Human | 15099 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qp4 | B | A | n-cyclohexyl-9h-purin-6-amine | Human | 6086 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv0 | A | A | n-cyclohexyl-4-[3-(4-fluorophenyl)-1h-pyrazol-4-yl]pyridin-2-amine | Human | 2562 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aoh | A | A | ~{n}-(6,7-dihydro-4~{h}-pyrano[4,3-d][1,3]thiazol-2-yl)propanamide | Human | 14385 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5nhp | A | | 5-(2-methoxyethyl)-1-methyl-2-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydropyrrolo[3,2-c]pyridin-4-one | Human | 7998 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qp1 | B | | n-benzyl-9h-purin-6-amine | Human | 6080 | |
| MAPK9 (JNK2) | MAPK | CMGC | 7cml | B | B | - | Human | 12704 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6oph | A | | 1-[(1~{s})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one | Human | 11509 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4h3q | A | | phosphoaminophosphonic acid-adenylate ester | Human | 2611 | |
| MAPK1 (Erk2) | MAPK | CMGC | 2ojj | A | | (s)-n-(1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl)-4-(4-(3-chlorophenyl)-1h-pyrazol-3-yl)-1h-pyrrole-2-carboxamide | Human | 2612 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g97 | A | B | 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2-(2-methoxyethyl)-3~{h}-isoindol-1-one | Human | 9970 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7nr5 | A | A | (2~{r})-2-[5-[5-chloranyl-2-[(2-methyl-1,2,3-triazol-4-yl)amino]pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{s})-1-(3-fluoranyl-5-methoxy-phenyl)-2-oxidanyl-ethyl]propanamide | Human | 13921 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4iz7 | C | A | - | Human | 2569 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6q7s | A | A | - | Human | 11349 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4iz5 | A | | adenosine-5'-diphosphate | Human | 2554 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qpa | A | | 7-(1-benzyl-1h-pyrazol-4-yl)-2-(pyridin-4-yl)-5h-pyrrolo[2,3-b]pyrazine | Human | 6077 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4iz7 | C | B | - | Human | 2597 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fux | A | | trans-4-{[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)pyrimidin-2-yl]amino}cyclohexanol | Human | 2568 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g9m | A | B | 2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-(2-phenylpropan-2-yl)ethanamide | Human | 9944 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6qaq | A | B | thiophen-3-ylmethylazanium | Human | 10989 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7nr3 | A | A | 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2-[2-oxidanylidene-2-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]-3~{h}-isoindol-1-one | Human | 13923 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g93 | A | B | 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2,3-dihydroisoindol-1-one | Human | 9959 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qp4 | A | A | n-cyclohexyl-9h-purin-6-amine | Human | 6088 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5ngu | A | | 2-[2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one | Human | 7991 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6qaq | A | A | thiophen-3-ylmethylazanium | Human | 10983 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7nqw | A | B | 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2-[2-oxidanylidene-2-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)ethyl]-3~{h}-isoindol-1-one | Human | 13924 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6qa3 | A | B | pyrazole | Human | 11345 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4n0s | A | A | caffeic acid | Human | 2589 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5nhh | A | | 5-(2-methoxyethyl)-2-[2-(oxan-4-ylamino)pyrimidin-4-yl]-6,7-dihydro-1~{h}-pyrrolo[3,2-c]pyridin-4-one | Human | 7996 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4zzn | A | B | 2-[[5-chloranyl-2-(oxan-4-ylamino)pyridin-4-yl]amino]-n-methyl-benzamide | Human | 2610 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4o6e | A | A | n-[(1s)-1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl]-2-(tetrahydro-2h-pyran-4-ylamino)-5,8-dihydropyrido[3,4-d]pyrimidine-7(6h)-carboxamide | Human | 2559 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4nif | E | A | phosphoaminophosphonic acid-adenylate ester | Human | 2621 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g54 | A | B | n-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propanamide | Human | 10937 | |
| MAPK1 (Erk2) | MAPK | CMGC | 7e73 | A | | - | Human | 14114 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6gdm | A | A | (3~{r})-1-[2-oxidanylidene-2-[4-(4-pyrimidin-2-ylphenyl)piperazin-1-yl]ethyl]-~{n}-(3-pyridin-4-yl-1~{h}-indazol-5-yl)pyrrolidine-3-carboxamide | Human | 9968 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g9m | A | A | 2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-(2-phenylpropan-2-yl)ethanamide | Human | 9964 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv1 | A | A | n-[(1s)-2-hydroxy-1-phenylethyl]-4-{4-[3-(trifluoromethyl)phenyl]-1h-pyrazol-5-yl}-1h-pyrrole-2-carboxamide | Human | 2594 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g9d | A | B | ~{n}-~{tert}-butyl-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]ethanamide | Human | 9953 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6qag | A | A | 1~{h}-1,2,3-triazole | Human | 10988 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g9k | A | A | 2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{s})-2-oxidanyl-1-phenyl-ethyl]ethanamide | Human | 9966 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qp6 | A | | 5h-pyrrolo[2,3-b]pyrazine | Human | 6089 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fmq | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 2604 | |
| MAPK1 (Erk2) | MAPK | CMGC | 2ojg | A | | n,n-dimethyl-4-(4-phenyl-1h-pyrazol-3-yl)-1h-pyrrole-2-carboxamide | Human | 2603 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g8x | A | B | 4-chloranyl-1~{h}-indazol-3-amine | Human | 9954 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g9n | A | A | (2~{r})-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{s})-1-(3-methylphenyl)-2-oxidanyl-ethyl]propanamide | Human | 11410 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv3 | A | B | ethyl n-{2-chloro-4-[5-(5-{[(1s)-1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl]carbamoyl}-1h-pyrrol-3-yl)-1h-pyrazol-4-yl]benzyl}glycinate | Human | 2580 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4xj0 | A | | 1-[(1s)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-(tetrahydro-2h-pyran-4-ylamino)pyrimidin-4-yl]pyridin-2(1h)-one | Human | 6048 | |
| MAPK1 (Erk2) | MAPK | CMGC | 1pme | A | | 4-[5-(4-fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-3h-imidazol-4-yl]-pyridine | Human | 2583 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv2 | A | B | 4-[4-(3-chlorophenyl)-1h-pyrazol-5-yl]-n-(2,3-dihydro-1-benzofuran-5-ylmethyl)-1h-pyrrole-2-carboxamide | Human | 2571 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4h3p | A | | phosphoaminophosphonic acid-adenylate ester | Human | 2624 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aob | A | A | ~{n}-[(1-methylindazol-3-yl)methyl]propanamide | Human | 14402 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4iza | C | A | - | Human | 2588 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6qa4 | A | A | 1~{h}-pyridin-2-one | Human | 11344 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8psr | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 15300 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5buj | A | B | 4-[3-(pyridin-4-yl)-2,4,6,7-tetrahydro-5h-pyrazolo[4,3-c]pyridin-5-yl]pyridin-2(1h)-one | Human | 2561 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5ax3 | A | | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 6398 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6gdm | A | B | (3~{r})-1-[2-oxidanylidene-2-[4-(4-pyrimidin-2-ylphenyl)piperazin-1-yl]ethyl]-~{n}-(3-pyridin-4-yl-1~{h}-indazol-5-yl)pyrrolidine-3-carboxamide | Human | 9946 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6dmg | A | B | ethyl n-{2-chloro-4-[5-(5-{[(1s)-1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl]carbamoyl}-1h-pyrrol-3-yl)-1h-pyrazol-4-yl]benzyl}glycinate | Human | 10810 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aog | A | A | ~{n}-(5-methyl-1,2-oxazol-3-yl)propanamide | Human | 14403 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv8 | A | B | 6-({4-[(3-cyclopropyl-1h-pyrazol-5-yl)amino]-5-(phenylamino)pyrimidin-2-yl}amino)-1,2-dihydro-3h-indazol-3-one | Human | 2601 | |
| MAPK1 (Erk2) | MAPK | CMGC | 3i60 | A | | 4-{2-[(2-chlorophenyl)amino]-5-methylpyrimidin-4-yl}-n-[(1s)-2-hydroxy-1-phenylethyl]-1h-pyrrole-2-carboxamide | Human | 2584 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv6 | A | | n-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-4-(2-{[(2s)-1-hydroxybutan-2-yl]amino}-5-methylpyrimidin-4-yl)-1h-pyrrole-2-carboxamide | Human | 2551 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5nhv | A | | 7-[2-(oxan-4-ylamino)pyrimidin-4-yl]-3,4-dihydro-2~{h}-pyrrolo[1,2-a]pyrazin-1-one | Human | 7995 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6qal | A | A | 1,1-bis(oxidanylidene)thietan-3-ol | Human | 10987 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv9 | A | A | 3-[4-(2,3-difluorophenyl)-1,2-oxazol-5-yl]-5-(pyridin-4-yl)-1h-pyrrolo[2,3-b]pyridine | Human | 2582 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4iz5 | C | | adenosine-5'-diphosphate | Human | 2595 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g92 | A | A | ~{n}-(1,5-dimethylpyrazol-4-yl)-5-methyl-pyrimidin-2-amine | Human | 11409 | |
| MAPK1 (Erk2) | MAPK | CMGC | 3sa0 | A | B | norathyriol | Human | 2557 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5lcj | A | B | [(1~{r},4~{z})-cyclooct-4-en-1-yl] ~{n}-[4-[4-[[5-chloranyl-4-[[2-(propanoylamino)phenyl]amino]pyrimidin-2-yl]amino]pyridin-2-yl]but-3-ynyl]carbamate | Human | 6834 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5v60 | A | B | phosphomethylphosphonic acid adenylate ester | Human | 8263 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6opi | A | | (3r)-n-[3-(2-cyclopropylpyridin-4-yl)-1h-indazol-5-yl]-3-(methoxymethyl)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]-3,6-dihydropyridin-1(2h)-yl}ethyl)pyrrolidine-3-carboxamide | Human | 11511 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g9k | A | B | 2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{s})-2-oxidanyl-1-phenyl-ethyl]ethanamide | Human | 9947 | |
| MAPK1 (Erk2) | MAPK | CMGC | 2oji | A | | n-benzyl-4-[4-(3-chlorophenyl)-1h-pyrazol-3-yl]-1h-pyrrole-2-carboxamide | Human | 2570 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6qaw | A | B | [1-(7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methylazanium | Human | 10986 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bvf | A | B | 2-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-8-(2-{[(1s,3r)-3-hydroxycyclopentyl]amino}pyrimidin-4-yl)-2,3,4,5-tetrahydro-1h-pyrrolo[1,2-a][1,4]diazepin-1-one | Human | 6027 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qp4 | A | B | n-cyclohexyl-9h-purin-6-amine | Human | 6075 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qp8 | B | | 2-(1h-pyrazol-4-yl)-7-(pyridin-3-yl)-5h-pyrrolo[2,3-b]pyrazine | Human | 6076 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv2 | A | A | 4-[4-(3-chlorophenyl)-1h-pyrazol-5-yl]-n-(2,3-dihydro-1-benzofuran-5-ylmethyl)-1h-pyrrole-2-carboxamide | Human | 2592 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8pt0 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 15307 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8aof | A | B | ~{n}-(2-methylpyrimidin-5-yl)propanamide | Human | 14408 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g9j | A | A | 2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{r})-1-phenylethyl]ethanamide | Human | 9952 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qp3 | B | | (2s)-3-phenyl-2-(9h-purin-6-ylamino)propan-1-ol | Human | 6079 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv7 | A | A | 4-(3-chlorophenyl)-5-{2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}-2-{[2-(piperidin-1-yl)ethyl]amino}thiophene-3-carbonitrile | Human | 2572 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4nif | B | B | phosphoaminophosphonic acid-adenylate ester | Human | 2566 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fuy | A | B | {4-[4-(3,5-dichlorophenyl)-1h-pyrazol-5-yl]-1h-pyrrol-2-yl}(morpholin-4-yl)methanone | Human | 2587 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4iza | A | A | - | Human | 2586 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qp9 | A | | 7-(1-propyl-1h-pyrazol-4-yl)-2-(pyridin-4-yl)-5h-pyrrolo[2,3-b]pyrazine | Human | 6085 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qpa | B | | 7-(1-benzyl-1h-pyrazol-4-yl)-2-(pyridin-4-yl)-5h-pyrrolo[2,3-b]pyrazine | Human | 6090 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qte | A | A | 4-{2-[(2-chloro-4-fluorophenyl)amino]-5-methylpyrimidin-4-yl}-n-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-1h-pyrrole-2-carboxamide | Human | 2590 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8pt1 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 15309 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8psw | A | A | amp phosphoramidate | Human | 15310 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6dmg | A | C | ethyl n-{2-chloro-4-[5-(5-{[(1s)-1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl]carbamoyl}-1h-pyrrol-3-yl)-1h-pyrazol-4-yl]benzyl}glycinate | Human | 10809 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6qa1 | A | B | pyridin-2-amine | Human | 11346 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv9 | A | B | 3-[4-(2,3-difluorophenyl)-1,2-oxazol-5-yl]-5-(pyridin-4-yl)-1h-pyrrolo[2,3-b]pyridine | Human | 2552 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qp4 | B | B | n-cyclohexyl-9h-purin-6-amine | Human | 6083 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8ao4 | A | A | ~{n}-(1~{h}-indazol-5-yl)ethanesulfonamide | Human | 14416 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g93 | A | A | 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2,3-dihydroisoindol-1-one | Human | 9955 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qp6 | B | | 5h-pyrrolo[2,3-b]pyrazine | Human | 6091 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5nhl | A | | (6~{r})-5-(2-methoxyethyl)-6-methyl-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydro-1~{h}-pyrrolo[3,2-c]pyridin-4-one | Human | 7992 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6d5y | A | | - | Human | 10939 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv4 | A | B | 9-(dimethylamino)-2-[(3-hydroxyphenyl)amino]-5,6-dihydrothieno[3,4-h]quinazoline-7-carbonitrile | Human | 2558 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6q7s | A | B | - | Human | 11343 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g92 | A | B | ~{n}-(1,5-dimethylpyrazol-4-yl)-5-methyl-pyrimidin-2-amine | Human | 11411 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qp1 | A | | n-benzyl-9h-purin-6-amine | Human | 6092 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6ge0 | A | A | 2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{h}-isoindol-2-yl]-~{n}-[(1~{r})-1-(3-methoxyphenyl)ethyl]ethanamide | Human | 9950 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6rq4 | A | B | 6,6-dimethyl-2-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-5-(2-morpholin-4-ylethyl)thieno[2,3-c]pyrrol-4-one | Human | 11855 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv7 | A | B | 4-(3-chlorophenyl)-5-{2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}-2-{[2-(piperidin-1-yl)ethyl]amino}thiophene-3-carbonitrile | Human | 2614 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6nbs | A | B | - | Human | 11508 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6qag | A | B | 1~{h}-1,2,3-triazole | Human | 10982 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4qp2 | A | | 5-chloro-1,3-benzoxazol-2-amine | Human | 6078 | |
| MAPK1 (Erk2) | MAPK | CMGC | 2y9q | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 2556 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv1 | A | B | n-[(1s)-2-hydroxy-1-phenylethyl]-4-{4-[3-(trifluoromethyl)phenyl]-1h-pyrazol-5-yl}-1h-pyrrole-2-carboxamide | Human | 2613 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5lcj | A | A | [(1~{r},4~{z})-cyclooct-4-en-1-yl] ~{n}-[4-[4-[[5-chloranyl-4-[[2-(propanoylamino)phenyl]amino]pyrimidin-2-yl]amino]pyridin-2-yl]but-3-ynyl]carbamate | Human | 6833 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5nhj | A | | 5-(2-methoxyethyl)-2-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydro-1~{h}-pyrrolo[3,2-c]pyridin-4-one | Human | 7994 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4iz5 | B | | adenosine-5'-diphosphate | Human | 2600 | |
| MAPK1 (Erk2) | MAPK | CMGC | 3sa0 | A | A | norathyriol | Human | 2596 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6qah | A | A | 1-azanylpropylideneazanium | Human | 11354 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6qaw | A | A | [1-(7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methylazanium | Human | 10984 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bui | A | | 3-(4-fluorophenyl)-5-(pyridin-2-yl)-4,5,6,7-tetrahydro-2h-pyrazolo[4,3-c]pyridine | Human | 2563 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6gjd | A | B | cyclooctyl ~{n}-[3-[[4-[5-[[(3~{r})-1-[2-oxidanylidene-2-[4-(4-pyrimidin-2-ylphenyl)piperazin-1-yl]ethyl]pyrrolidin-3-yl]carbonylamino]-1~{h}-indazol-3-yl]pyridin-2-yl]carbonylamino]propyl]carbamate | Human | 10830 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4zzo | A | A | n-[2-[[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]amino]phenyl]propanamide | Human | 2620 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4o6e | A | B | n-[(1s)-1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl]-2-(tetrahydro-2h-pyran-4-ylamino)-5,8-dihydropyrido[3,4-d]pyrimidine-7(6h)-carboxamide | Human | 2553 | |
| MAPK13 (p38d) | MAPK | CMGC | 4myg | A | | - | Human | 2951 | |
| MAPK13 (p38d) | MAPK | CMGC | 4myg | B | | - | Human | 2950 | |
| MAPK13 (p38d) | MAPK | CMGC | 8x23 | A | A | - | Human | 15129 | |
| MAPK13 (p38d) | MAPK | CMGC | 5eko | A | | 3-(4-methyl-1h-imidazol-1-yl)-n-[4-(pyridin-4-yloxy)phenyl]benzamide | Human | 6746 | |
| MAPK13 (p38d) | MAPK | CMGC | 3coi | A | A | - | Human | 2948 | |
| MAPK13 (p38d) | MAPK | CMGC | 4eyj | A | | 1-(3-tert-butyl-1-methyl-1h-pyrazol-5-yl)-3-[4-(pyridin-4-yloxy)phenyl]urea | Human | 2949 | |
| MAPK13 (p38d) | MAPK | CMGC | 5ekn | A | | 1-(3-tert-butyl-1-methyl-1h-pyrazol-5-yl)-3-[4-(pyridin-4-ylsulfanyl)phenyl]urea | Human | 6745 | |
| MAPK13 (p38d) | MAPK | CMGC | 4eym | A | | 2-(morpholin-4-yl)-n-[4-(pyridin-4-yloxy)phenyl]pyridine-4-carboxamide | Human | 2945 | |
| MAPK13 (p38d) | MAPK | CMGC | 3coi | A | B | - | Human | 2946 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3v6r | B | A | 4-{[4-(dimethylamino)butanoyl]amino}-n-(3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide | Human | 3427 | |
| MAPK10 (JNK3) | MAPK | CMGC | 2o2u | A | | n-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-fluorobenzamide | Human | 3457 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3g90 | X | | (3e)-5-fluoro-1-[(6-fluoro-4h-1,3-benzodioxin-8-yl)methyl]-1h-indole-2,3-dione 3-oxime | Human | 3477 | |
| MAPK10 (JNK3) | MAPK | CMGC | 6eq9 | A | B | phosphomethylphosphonic acid adenylate ester | Human | 10509 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3fv8 | A | B | 5-bromo-n-(3-chloro-2-(4-(prop-2-ynyl)piperazin-1-yl)phenyl)furan-2-carboxamide | Human | 3426 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3da6 | A | | n-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)naphthalen-1-yl]-1h-benzimidazol-2-amine | Human | 3476 | |
| MAPK10 (JNK3) | MAPK | CMGC | 6emh | B | B | 4-(4-methyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amine | Human | 10501 | |
| MAPK10 (JNK3) | MAPK | CMGC | 8vs0 | A | | (4p)-4-[6-fluoro-5-(2-methoxyanilino)-1h-indazol-1-yl]-5-methyl-n-(oxetan-3-yl)thiophene-2-carboxamide | Human | 15635 | |
| MAPK10 (JNK3) | MAPK | CMGC | 2r9s | A | | n-(tert-butyl)-4-[5-(pyridin-2-ylamino)quinolin-3-yl]benzenesulfonamide | Human | 3450 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4h39 | A | A | - | Human | 3460 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4kkg | A | | - | Human | 3443 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3cgo | A | | 2-{4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]piperidin-1-yl}-n-methylacetamide | Human | 6771 | |
| MAPK10 (JNK3) | MAPK | CMGC | 8vtf | A | | (4p)-4-[6-fluoro-5-(2-methoxyanilino)-1h-indazol-1-yl]-n-(oxetan-3-yl)thiophene-2-carboxamide | Human | 15636 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3oy1 | A | | 5-[2-(cyclohexylamino)pyridin-4-yl]-4-naphthalen-2-yl-2-(tetrahydro-2h-pyran-4-yl)-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | 3469 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4h3b | C | A | - | Human | 3475 | |
| MAPK10 (JNK3) | MAPK | CMGC | 7ore | A | B | 4-(dimethylamino)-n-[(5z)-9-[[4-[5-(4-fluorophenyl)-3-methyl-2-methylsulfanyl-imidazol-4-yl]pyridin-2-yl]amino]-11,12-dihydrobenzo[c][1,2]benzodiazocin-2-yl]butanamide | Human | 13810 | |
| MAPK10 (JNK3) | MAPK | CMGC | 6ekd | A | B | 4-(4-methyl-2-methylsulfanyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amine | Human | 10502 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4y46 | A | | 1-{trans-4-[(8-cyclopentyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]cyclohexyl}-3-propan-2-ylurea | Human | 3414 | |
| MAPK10 (JNK3) | MAPK | CMGC | 7ore | A | A | 4-(dimethylamino)-n-[(5z)-9-[[4-[5-(4-fluorophenyl)-3-methyl-2-methylsulfanyl-imidazol-4-yl]pyridin-2-yl]amino]-11,12-dihydrobenzo[c][1,2]benzodiazocin-2-yl]butanamide | Human | 13811 | |
| MAPK10 (JNK3) | MAPK | CMGC | 2b1p | A | | 3-{6-[(2-chlorophenyl)amino]-1h-indazol-3-yl}-5-{[4-(dimethylamino)butanoyl]amino}benzoic acid | Human | 3464 | |
| MAPK10 (JNK3) | MAPK | CMGC | 1pmu | A | | 9-(4-hydroxyphenyl)-2,7-phenanthroline | Human | 3474 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4h3b | A | A | - | Human | 3480 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4z9l | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 3432 | |
| MAPK10 (JNK3) | MAPK | CMGC | 7orf | A | A | n-[4-[[4-[5-(4-fluorophenyl)-3-methyl-2-methylsulfanyl-imidazol-4-yl]pyridin-2-yl]amino]phenyl]-3-(propanoylamino)benzamide | Human | 13812 | |
| MAPK10 (JNK3) | MAPK | CMGC | 6emh | A | A | 4-(4-methyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amine | Human | 10508 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3ttj | A | B | 9-cyclopentyl-n~8~-(2-fluorophenyl)-n~2~-(4-methoxyphenyl)-9h-purine-2,8-diamine | Human | 3428 | |
| MAPK10 (JNK3) | MAPK | CMGC | 2r9s | B | | n-(tert-butyl)-4-[5-(pyridin-2-ylamino)quinolin-3-yl]benzenesulfonamide | Human | 3420 | |
| MAPK10 (JNK3) | MAPK | CMGC | 7ksi | A | | 4-(4-{[(2-chloro-6-fluorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-5-methyl-n-(oxetan-3-yl)thiophene-2-carboxamide | Human | 13387 | |
| MAPK10 (JNK3) | MAPK | CMGC | 1jnk | A | | phosphoaminophosphonic acid-adenylate ester | Human | 3451 | |
| MAPK10 (JNK3) | MAPK | CMGC | 6eq9 | A | A | phosphomethylphosphonic acid adenylate ester | Human | 10500 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3g9n | A | | (3z)-1-[(6-fluoro-4h-1,3-benzodioxin-8-yl)methyl]-4-phenyl-1h-indole-2,3-dione 3-oxime | Human | 3416 | |
| MAPK10 (JNK3) | MAPK | CMGC | 7ore | A | C | 4-(dimethylamino)-n-[(5z)-9-[[4-[5-(4-fluorophenyl)-3-methyl-2-methylsulfanyl-imidazol-4-yl]pyridin-2-yl]amino]-11,12-dihydrobenzo[c][1,2]benzodiazocin-2-yl]butanamide | Human | 13813 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4kkh | A | | cyclopropyl[(3r)-3-({4-[6-hydroxy-2-(naphthalen-2-yl)-1h-benzimidazol-1-yl]pyrimidin-2-yl}amino)piperidin-1-yl]methanone | Human | 3419 | |
| MAPK10 (JNK3) | MAPK | CMGC | 3ptg | A | | n-[4-methyl-3-(1h-1,2,4-triazol-5-yl)thiophen-2-yl]-2-(2-oxo-3,4-dihydroquinolin-1(2h)-yl)acetamide | Human | 3470 | |
| MAPK10 (JNK3) | MAPK | CMGC | 7ksj | A | | 4-(4-{[(2-chloro-6-fluorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-n-(oxetan-3-yl)thiophene-2-carboxamide | Human | 13388 | |
| MAPK10 (JNK3) | MAPK | CMGC | 2waj | A | B | 1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline | Human | 3471 | |
| MAPK10 (JNK3) | MAPK | CMGC | 2ok1 | A | B | n-benzyl-4-[4-(3-chlorophenyl)-1h-pyrazol-3-yl]-1h-pyrrole-2-carboxamide | Human | 3473 | |
| MAPK10 (JNK3) | MAPK | CMGC | 4w4y | A | | 3-(4-{[(4-methylphenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-n-(2-methylpyridin-4-yl)benzamide | Human | 3447 | |
| MAPK10 (JNK3) | MAPK | CMGC | 6ekd | A | A | 4-(4-methyl-2-methylsulfanyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amine | Human | 10498 | |
| MAPK14 (p38a) | MAPK | CMGC | 4r3c | A | A | 6-(4-methylpiperazin-1-yl)-3-(naphthalen-2-yl)-4-(pyridin-4-yl)pyridazine | Human | 5198 | |
| MAPK14 (p38a) | MAPK | CMGC | 3ctq | A | | n-benzyl-1-[5-({5-tert-butyl-2-methoxy-3-[(methylsulfonyl)amino]phenyl}carbamoyl)-2-methylphenyl]-1h-1,2,3-triazole-4-carboxamide | Human | 5220 | |
| MAPK14 (p38a) | MAPK | CMGC | 5tco | A | | 3-[(3-benzamido-4-fluoranyl-phenyl)amino]-~{n}-(2-morpholin-4-ylethyl)-11-oxidanylidene-5,6-dihydrodibenzo[1,2-~{d}:1',2'-~{f}][7]annulene-9-carboxamide | Human | 8031 | |
| MAPK14 (p38a) | MAPK | CMGC | 2gfs | A | B | [5-amino-1-(4-fluorophenyl)-1h-pyrazol-4-yl](3-{[(2r)-2,3-dihydroxypropyl]oxy}phenyl)methanone | Human | 5050 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hv5 | A | A | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-{3-[(6-nitroquinolin-4-yl)amino]phenyl}urea | Human | 5203 | |
| MAPK14 (p38a) | MAPK | CMGC | 3nnv | A | A | 1-{3-tert-butyl-1-[4-(hydroxymethyl)phenyl]-1h-pyrazol-5-yl}-3-naphthalen-1-ylurea | Human | 5037 | |
| MAPK14 (p38a) | MAPK | CMGC | 3ds6 | A | | n-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide | Human | 5074 | |
| MAPK14 (p38a) | MAPK | CMGC | 4dli | A | | - | Human | 5092 | |
| MAPK14 (p38a) | MAPK | CMGC | 2y8o | A | A | - | Human | 5079 | |
| MAPK14 (p38a) | MAPK | CMGC | 3oef | X | B | - | Human | 5231 | |
| MAPK14 (p38a) | MAPK | CMGC | 5tbe | A | | ~{n}-[2,4-bis(fluoranyl)-5-[[9-(2-morpholin-4-ylethylcarbamoyl)-11-oxidanylidene-5,6-dihydrodibenzo[1,2-~{d}:1',2'-~{f}][7]annulen-3-yl]amino]phenyl]thiophene-2-carboxamide | Human | 8032 | |
| MAPK14 (p38a) | MAPK | CMGC | 3k3j | A | | 2-(4-fluorophenyl)-3-oxo-6-pyridin-4-yl-n-[2-(trifluoromethyl)benzyl]-2,3-dihydropyridazine-4-carboxamide | Human | 5047 | |
| MAPK14 (p38a) | MAPK | CMGC | 6sfj | A | C | ~{n}-[5-[[(2~{s})-1-azanyl-4-cyclohexyl-1-oxidanylidene-butan-2-yl]carbamoyl]-2-methyl-phenyl]-1-(2-methylphenyl)pyrazole-4-carboxamide | Human | 11618 | |
| MAPK14 (p38a) | MAPK | CMGC | 5omg | A | A | 3-(4-fluorophenyl)-4-methyl-1~{h}-pyrazolo[4,3-c][1,2]benzothiazine 5,5-dioxide | Human | 11246 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hrb | A | | [3-amino-2-(2-methylphenyl)-1-oxidopyridin-4-yl](2,4-difluorophenyl)methanone | Human | 5202 | |
| MAPK14 (p38a) | MAPK | CMGC | 1w84 | A | | 3-(2-pyridin-4-ylethyl)-1h-indole | Human | 5065 | |
| MAPK14 (p38a) | MAPK | CMGC | 2gfs | A | A | [5-amino-1-(4-fluorophenyl)-1h-pyrazol-4-yl](3-{[(2r)-2,3-dihydroxypropyl]oxy}phenyl)methanone | Human | 5227 | |
| MAPK14 (p38a) | MAPK | CMGC | 3u8w | A | | 3-[3-(2-chloro-6-fluorophenyl)-5-ethyl-6-oxo-5,6-dihydro[1,2,4]triazolo[4,3-b]pyridazin-7-yl]-n-cyclopropyl-4-methylbenzamide | Human | 5192 | |
| MAPK14 (p38a) | MAPK | CMGC | 3huc | A | A | n-[2-phenyl-4-(1h-pyrazol-3-ylamino)quinazolin-7-yl]prop-2-enamide | Human | 5027 | |
| MAPK14 (p38a) | MAPK | CMGC | 4kiq | A | | ethyl 6-{[5-(cyclopropylcarbamoyl)-2-methylphenyl]carbamoyl}-1h-indole-1-carboxylate | Human | 5141 | |
| MAPK14 (p38a) | MAPK | CMGC | 1wbt | A | | 3-fluoro-5-morpholin-4-yl-n-[1-(2-pyridin-4-ylethyl)-1h-indol-6-yl]benzamide | Human | 5082 | |
| MAPK14 (p38a) | MAPK | CMGC | 3k3i | A | B | (3s)-3-[4-(4-bromophenyl)-1h-imidazol-2-yl]-1,2,3,4-tetrahydroisoquinoline | Human | 5022 | |
| MAPK14 (p38a) | MAPK | CMGC | 3nnw | A | B | 2-[3-(3-tert-butyl-5-{[(2,3-dichlorophenyl)carbamoyl]imino}-2,5-dihydro-1h-pyrazol-1-yl)phenyl]acetamide | Human | 5138 | |
| MAPK14 (p38a) | MAPK | CMGC | 5mtx | A | B | 3-[(3-benzamido-4-fluoranyl-phenyl)amino]-~{n}-(2-morpholin-4-ylethyl)-11-oxidanylidene-6~{h}-benzo[c][1]benzoxepine-9-carboxamide | Human | 8379 | |
| MAPK14 (p38a) | MAPK | CMGC | 6sfi | A | A | ~{n}-[(2~{s})-1-azanyl-4-cyclohexyl-1-oxidanylidene-butan-2-yl]-2-[[[1-(2-methylphenyl)pyrazol-4-yl]carbonylamino]methyl]-1,3-thiazole-5-carboxamide | Human | 11613 | |
| MAPK14 (p38a) | MAPK | CMGC | 6sfo | A | B | 5-azanyl-~{n}-[[4-(3-cyclohexylpropylcarbamoyl)phenyl]methyl]-1-phenyl-pyrazole-4-carboxamide | Human | 11621 | |
| MAPK14 (p38a) | MAPK | CMGC | 1w83 | A | | n-[4-chloro-3-(pyridin-3-yloxymethyl)-phenyl]-3-fluoro- | Human | 4986 | |
| MAPK14 (p38a) | MAPK | CMGC | 5mty | A | | ~{n}-[2,4-bis(fluoranyl)-5-[[14-(2-hydroxyethylcarbamoyl)-2-oxidanylidene-6-tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaenyl]amino]phenyl]thiophene-2-carboxamide | Human | 8383 | |
| MAPK14 (p38a) | MAPK | CMGC | 5o8v | A | | - | Human | 8380 | |
| MAPK14 (p38a) | MAPK | CMGC | 3lfb | A | B | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-(1,3-thiazol-2-yl)urea | Human | 5001 | |
| MAPK14 (p38a) | MAPK | CMGC | 5etf | A | A | - | Human | 7134 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fsf | A | | 3-(2,6-dichlorophenyl)-7-({4-[(diethylamino)methoxy]phenyl}amino)-1-methyl-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 5097 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fmk | A | | 6-(2,4-difluorophenoxy)-8-methyl-2-{[(1s)-1-methyl-2-(2h-tetrazol-2-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 5209 | |
| MAPK14 (p38a) | MAPK | CMGC | 3uvq | A | A | n-{5-[(7-{[(2r)-2,3-dihydroxypropyl]oxy}-5-oxo-10,11-dihydro-5h-dibenzo[a,d][7]annulen-2-yl)amino]-2-fluorophenyl}benzamide | Human | 5183 | |
| MAPK14 (p38a) | MAPK | CMGC | 4eh9 | A | | - | Human | 4982 | |
| MAPK14 (p38a) | MAPK | CMGC | 1bl6 | A | | 4-(4-fluorophenyl)-1-cycloropropylmethyl-5-(4-pyridyl)-imidazole | Human | 5243 | |
| MAPK14 (p38a) | MAPK | CMGC | 6tca | D | A | n-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1h-pyrazole-4-carboxamide | Human | 12486 | |
| MAPK14 (p38a) | MAPK | CMGC | 6sfk | A | B | ~{n}-[5-[[(2~{s})-1-azanyl-4-cyclohexyl-1-oxidanylidene-butan-2-yl]carbamoyl]-2-methyl-phenyl]-1-phenyl-5-(trifluoromethyl)pyrazole-4-carboxamide | Human | 11620 | |
| MAPK14 (p38a) | MAPK | CMGC | 3iph | A | B | 6-[5-(cyclopropylcarbamoyl)-2-methylphenyl]-n-(cyclopropylmethyl)pyridine-3-carboxamide | Human | 5156 | |
| MAPK14 (p38a) | MAPK | CMGC | 3pg3 | A | A | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-{4-[2-(pyridin-3-ylmethoxy)ethyl]-1,3-thiazol-2-yl}urea | Human | 5122 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fls | A | | 6-(2,4-difluorophenoxy)-8-methyl-2-{[(1r)-1-methyl-2-(methylsulfonyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 5119 | |
| MAPK14 (p38a) | MAPK | CMGC | 3que | A | | 2-[(2,4-difluorophenyl)amino]-7-{[(2r)-2,3-dihydroxypropyl]oxy}-10,11-dihydro-5h-dibenzo[a,d][7]annulen-5-one | Human | 5095 | |
| MAPK14 (p38a) | MAPK | CMGC | 6hwt | A | B | 3-(2,5-dimethoxyphenyl)-~{n}-[4-[4-(4-fluorophenyl)-2-(2-phenylhydrazinyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide | Human | 11254 | |
| MAPK14 (p38a) | MAPK | CMGC | 3nnu | A | B | 2-{3-[(5e)-5-{[(2,3-dichlorophenyl)carbamoyl]imino}-3-thiophen-2-yl-2,5-dihydro-1h-pyrazol-1-yl]phenyl}acetamide | Human | 5059 | |
| MAPK14 (p38a) | MAPK | CMGC | 4kiq | C | | ethyl 6-{[5-(cyclopropylcarbamoyl)-2-methylphenyl]carbamoyl}-1h-indole-1-carboxylate | Human | 5215 | |
| MAPK14 (p38a) | MAPK | CMGC | 3mh3 | A | | - | Human | 5109 | |
| MAPK14 (p38a) | MAPK | CMGC | 3zsg | A | B | tak-715 | Human | 5098 | |
| MAPK14 (p38a) | MAPK | CMGC | 6sfj | A | B | ~{n}-[5-[[(2~{s})-1-azanyl-4-cyclohexyl-1-oxidanylidene-butan-2-yl]carbamoyl]-2-methyl-phenyl]-1-(2-methylphenyl)pyrazole-4-carboxamide | Human | 11616 | |
| MAPK14 (p38a) | MAPK | CMGC | 6qyx | A | | - | Human | 12127 | |
| MAPK14 (p38a) | MAPK | CMGC | 3flz | A | | 8-methyl-6-phenoxy-2-(tetrahydro-2h-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 5204 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hub | A | | 2-(6-chloro-5-{[(2r,5s)-4-(4-fluorobenzyl)-2,5-dimethylpiperazin-1-yl]carbonyl}-1-methyl-1h-indol-3-yl)-n,n-dimethyl-2-oxoacetamide | Human | 5029 | |
| MAPK14 (p38a) | MAPK | CMGC | 6hwv | A | A | - | Human | 11253 | |
| MAPK14 (p38a) | MAPK | CMGC | 2lgc | A | 2 | - | Human | 5093 | |
| MAPK14 (p38a) | MAPK | CMGC | 3new | A | A | - | Human | 5025 | |
| MAPK14 (p38a) | MAPK | CMGC | 3qud | A | B | {4-[(2-aminophenyl)amino]phenyl}(phenyl)methanone | Human | 5262 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gc7 | A | A | 5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-[1-(1-methylethyl)piperidin-4-yl]-3,4-dihydroquinazolin-2(1h)-one | Human | 5061 | |
| MAPK14 (p38a) | MAPK | CMGC | 4eh3 | A | | naringenin | Human | 5042 | |
| MAPK14 (p38a) | MAPK | CMGC | 3uvr | A | A | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-{3-[(5-oxo-6,7,8,9-tetrahydro-5h-benzo[7]annulen-2-yl)amino]phenyl}urea | Human | 6880 | |
| MAPK14 (p38a) | MAPK | CMGC | 6hwu | A | A | - | Human | 11247 | |
| MAPK14 (p38a) | MAPK | CMGC | 5mz3 | A | A | ~{n}-[3-(2-acetamidoimidazo[1,2-a]pyridin-6-yl)-4-methyl-phenyl]-3-(trifluoromethyl)benzamide | Human | 8680 | |
| MAPK14 (p38a) | MAPK | CMGC | 4eh2 | A | | 3-phenylquinazolin-4(3h)-one | Human | 5244 | |
| MAPK14 (p38a) | MAPK | CMGC | 2fsl | X | | - | Human | 5264 | |
| MAPK14 (p38a) | MAPK | CMGC | 2onl | A | | - | Human | 5177 | |
| MAPK14 (p38a) | MAPK | CMGC | 3ha8 | A | B | n~2~-{4-[6-(3,4-dihydroquinolin-1(2h)-ylcarbonyl)-1h-benzimidazol-1-yl]-6-ethoxy-1,3,5-triazin-2-yl}-3-(2,2-dimethyl-4h-1,3-benzodioxin-6-yl)-n-methyl-l-alaninamide | Human | 5187 | |
| MAPK14 (p38a) | MAPK | CMGC | 3mvm | B | | 4-{[5-(isoxazol-3-ylcarbamoyl)-2-methylphenyl]amino}-5-methyl-n-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide | Human | 5210 | |
| MAPK14 (p38a) | MAPK | CMGC | 3itz | A | | 4-chloro-n-cyclopropyl-3-{[1-(2,6-difluorophenyl)-1h-pyrazolo[3,4-d]pyridazin-4-yl]amino}benzamide | Human | 5135 | |
| MAPK14 (p38a) | MAPK | CMGC | 3kq7 | A | B | n-(2-methyl-5-{[(2-morpholin-4-ylpyridin-4-yl)carbonyl]amino}phenyl)-6-({2-[(2s)-1-methylpyrrolidin-2-yl]ethyl}amino)pyridine-3-carboxamide | Human | 5057 | |
| MAPK14 (p38a) | MAPK | CMGC | 6qe1 | A | | 1-[5-~{tert}-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[(1~{s},4~{r})-4-[(3-propan-2-yl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)oxy]-1,2,3,4-tetrahydronaphthalen-1-yl]urea | Human | 11957 | |
| MAPK14 (p38a) | MAPK | CMGC | 3uvp | A | A | n-{2-fluoro-5-[(5-oxo-6,7,8,9-tetrahydro-5h-benzo[7]annulen-2-yl)amino]phenyl}benzamide | Human | 5070 | |
| MAPK14 (p38a) | MAPK | CMGC | 3new | A | B | - | Human | 5248 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hv4 | A | | 1-{3-[(6-aminoquinolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]urea | Human | 5121 | |
| MAPK14 (p38a) | MAPK | CMGC | 3bx5 | A | | n-[2-methyl-5-(methylcarbamoyl)phenyl]-2-{[(1r)-1-methylpropyl]amino}-1,3-thiazole-5-carboxamide | Human | 5000 | |
| MAPK14 (p38a) | MAPK | CMGC | 3nnw | A | A | 2-[3-(3-tert-butyl-5-{[(2,3-dichlorophenyl)carbamoyl]imino}-2,5-dihydro-1h-pyrazol-1-yl)phenyl]acetamide | Human | 5139 | |
| MAPK14 (p38a) | MAPK | CMGC | 2fst | X | A | - | Human | 5080 | |
| MAPK14 (p38a) | MAPK | CMGC | 6tca | B | B | n-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1h-pyrazole-4-carboxamide | Human | 12488 | |
| MAPK14 (p38a) | MAPK | CMGC | 1kv1 | A | | 1-(5-tert-butyl-2-methyl-2h-pyrazol-3-yl)-3-(4-chloro-phenyl)-urea | Human | 5252 | |
| MAPK14 (p38a) | MAPK | CMGC | 2i0h | A | B | 2-(3-{(2-chloro-4-fluorophenyl)[1-(2-chlorophenyl)-6-oxo-1,6-dihydropyridazin-3-yl]amino}propyl)-1h-isoindole-1,3(2h)-dione | Human | 5009 | |
| MAPK14 (p38a) | MAPK | CMGC | 3pg3 | A | B | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-{4-[2-(pyridin-3-ylmethoxy)ethyl]-1,3-thiazol-2-yl}urea | Human | 5096 | |
| MAPK14 (p38a) | MAPK | CMGC | 4aa4 | A | | n-[4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxidanylidene-quinazolin-3-yl]phenyl]furan-3-carboxamide | Human | 5045 | |
| MAPK14 (p38a) | MAPK | CMGC | 1wbs | A | | 3-fluoro-5-morpholin-4-yl-n-[3-(2-pyridin-4-ylethyl)-1h-indol-5-yl]benzamide | Human | 5258 | |
| MAPK14 (p38a) | MAPK | CMGC | 1m7q | A | | 1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-piperazin-1-yl-3,4-dihydroquinazolin-2(1h)-one | Human | 5128 | |
| MAPK14 (p38a) | MAPK | CMGC | 4e6a | A | | - | Human | 5238 | |
| MAPK14 (p38a) | MAPK | CMGC | 3bv3 | A | | 5-methyl-4-[(2-methyl-5-{[(3-morpholin-4-ylphenyl)carbonyl]amino}phenyl)amino]-n-[(1s)-1-phenylethyl]pyrrolo[2,1-f][1,2,4]triazine-6-carboxamide | Human | 5207 | |
| MAPK14 (p38a) | MAPK | CMGC | 6tca | F | B | n-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1h-pyrazole-4-carboxamide | Human | 12490 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hec | A | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 5166 | |
| MAPK14 (p38a) | MAPK | CMGC | 3lff | A | A | (4-{3-tert-butyl-5-[(1,3-thiazol-2-ylcarbamoyl)amino]-1h-pyrazol-1-yl}phenyl)acetic acid | Human | 5140 | |
| MAPK14 (p38a) | MAPK | CMGC | 5eti | A | | - | Human | 6362 | |
| MAPK14 (p38a) | MAPK | CMGC | 6tca | B | A | n-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1h-pyrazole-4-carboxamide | Human | 12491 | |
| MAPK14 (p38a) | MAPK | CMGC | 1w82 | A | | n-[(3z)-5-tert-butyl-2-phenyl-1,2-dihydro-3h-pyrazol-3-ylidene]-n'-(4-chlorophenyl)urea | Human | 5165 | |
| MAPK14 (p38a) | MAPK | CMGC | 4geo | A | | - | Human | 5190 | |
| MAPK14 (p38a) | MAPK | CMGC | 6tca | D | B | n-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1h-pyrazole-4-carboxamide | Human | 12492 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gcs | A | A | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 5077 | |
| MAPK14 (p38a) | MAPK | CMGC | 3iw7 | A | | 2-({4-[(4-benzylpiperidin-1-yl)carbonyl]benzyl}sulfanyl)-3h-imidazo[4,5-c]pyridine | Human | 5084 | |
| MAPK14 (p38a) | MAPK | CMGC | 3d7z | A | B | n~3~-cyclopropyl-n~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide | Human | 5108 | |
| MAPK14 (p38a) | MAPK | CMGC | 6sfo | A | A | 5-azanyl-~{n}-[[4-(3-cyclohexylpropylcarbamoyl)phenyl]methyl]-1-phenyl-pyrazole-4-carboxamide | Human | 11615 | |
| MAPK14 (p38a) | MAPK | CMGC | 2zaz | A | A | 4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehyde | Human | 4980 | |
| MAPK14 (p38a) | MAPK | CMGC | 1r39 | A | | - | Human | 5116 | |
| MAPK14 (p38a) | MAPK | CMGC | 5omg | A | B | 3-(4-fluorophenyl)-4-methyl-1~{h}-pyrazolo[4,3-c][1,2]benzothiazine 5,5-dioxide | Human | 11245 | |
| MAPK14 (p38a) | MAPK | CMGC | 1a9u | A | | 4-[5-(4-fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-3h-imidazol-4-yl]-pyridine | Human | 5229 | |
| MAPK14 (p38a) | MAPK | CMGC | 3flq | A | | 6-(2,4-difluorophenoxy)-8-methyl-2-{[(1s)-1-methyl-2-(methylsulfonyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 5168 | |
| MAPK14 (p38a) | MAPK | CMGC | 3uvr | A | B | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-{3-[(5-oxo-6,7,8,9-tetrahydro-5h-benzo[7]annulen-2-yl)amino]phenyl}urea | Human | 6879 | |
| MAPK14 (p38a) | MAPK | CMGC | 3o8t | A | | 1-(5-tert-butyl-2-methyl-2h-pyrazol-3-yl)-3-(4-chloro-phenyl)-urea | Human | 5167 | |
| MAPK14 (p38a) | MAPK | CMGC | 3o8p | A | | 1-(5-tert-butyl-2-methyl-2h-pyrazol-3-yl)-3-(4-chloro-phenyl)-urea | Human | 5071 | |
| MAPK14 (p38a) | MAPK | CMGC | 2yis | A | | 1-[3-tert-butyl-1-(3-chloro-4-hydroxyphenyl)-1h-pyrazol-5-yl]-3-{2-[(3-{2-[(2-hydroxyethyl)sulfanyl]phenyl}[1,2,4]triazolo[4,3-a]pyridin-6-yl)sulfanyl]benzyl}urea | Human | 5240 | |
| MAPK14 (p38a) | MAPK | CMGC | 3iw6 | A | B | ethyl 4-[(4-benzylpiperazin-1-yl)carbonyl]-1-ethyl-3,5-dimethyl-1h-pyrrole-2-carboxylate | Human | 5154 | |
| MAPK14 (p38a) | MAPK | CMGC | 2qd9 | A | | 1-[(3ar)-5-{[3-(2,4-difluorophenyl)-5,6-dihydroimidazo[1,5-a]pyrazin-7(8h)-yl]carbonyl}-6-methoxy-3ah-pyrrolo[2,3-b]pyridin-3-yl]-2-[(3r)-3-hydroxypyrrolidin-1-yl]-2-oxoethanone | Human | 5197 | |
| MAPK14 (p38a) | MAPK | CMGC | 3mvl | B | | 4-{[5-(cyclopropylcarbamoyl)-2-methylphenyl]amino}-5-methyl-n-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide | Human | 5091 | |
| MAPK14 (p38a) | MAPK | CMGC | 1ove | A | A | 1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-piperidin-4-yl-3,4-dihydroquinolin-2(1h)-one | Human | 5178 | |
| MAPK14 (p38a) | MAPK | CMGC | 3iph | A | A | 6-[5-(cyclopropylcarbamoyl)-2-methylphenyl]-n-(cyclopropylmethyl)pyridine-3-carboxamide | Human | 4999 | |
| MAPK14 (p38a) | MAPK | CMGC | 6hwt | A | A | 3-(2,5-dimethoxyphenyl)-~{n}-[4-[4-(4-fluorophenyl)-2-(2-phenylhydrazinyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide | Human | 11248 | |
| MAPK14 (p38a) | MAPK | CMGC | 3l8s | A | | 3-[(4-bromo-2,6-difluorobenzyl)oxy]-5-{[(4-pyrrolidin-1-ylbutyl)carbamoyl]amino}isothiazole-4-carboxamide | Human | 5055 | |
| MAPK14 (p38a) | MAPK | CMGC | 4f9w | A | B | n,n-dimethyl-6-(naphthalen-2-yl)-5-(pyridin-4-yl)pyridazin-3-amine | Human | 5106 | |
| MAPK14 (p38a) | MAPK | CMGC | 6tca | H | A | n-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1h-pyrazole-4-carboxamide | Human | 12493 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fi4 | A | | (2s)-1-{[3-(2-chlorophenyl)-6-(2,4-difluorophenoxy)-1h-pyrazolo[3,4-d]pyrimidin-4-yl]amino}propan-2-ol | Human | 5051 | |
| MAPK14 (p38a) | MAPK | CMGC | 3o8u | A | | 1-(5-tert-butyl-2-methyl-2h-pyrazol-3-yl)-3-(4-chloro-phenyl)-urea | Human | 5250 | |
| MAPK14 (p38a) | MAPK | CMGC | 3s3i | A | | 3-(3-tert-butyl[1,2,4]triazolo[4,3-a]pyridin-7-yl)-n-cyclopropyl-4-methylbenzamide | Human | 5169 | |
| MAPK14 (p38a) | MAPK | CMGC | 3dt1 | A | | n-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethyl)amino]quinazolin-6-yl}benzamide | Human | 5086 | |
| MAPK14 (p38a) | MAPK | CMGC | 3lfd | A | | 1-{4-[2-(benzyloxy)ethyl]-1,3-thiazol-2-yl}-3-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]urea | Human | 5102 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gcv | A | B | 1-{3-[(6-aminoquinazolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(3-methylphenyl)-1h-pyrazol-5-yl]urea | Human | 5174 | |
| MAPK14 (p38a) | MAPK | CMGC | 1ouy | A | | 1-(2,6-dichlorophenyl)-6-[(2,4-difluorophenyl)sulfanyl]-7-(1,2,3,6-tetrahydro-4-pyridinyl)-3,4-dihydropyrido[3,2-d]pyrimidin-2(1h)-one | Human | 7258 | |
| MAPK14 (p38a) | MAPK | CMGC | 2zb1 | A | B | n-(cyclopropylmethyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide | Human | 5103 | |
| MAPK14 (p38a) | MAPK | CMGC | 5eta | A | | - | Human | 7136 | |
| MAPK14 (p38a) | MAPK | CMGC | 2yix | A | | 1-ethyl-3-(2-{[3-(1-methylethyl)[1,2,4]triazolo[4,3-a]pyridin-6-yl]sulfanyl}benzyl)urea | Human | 5143 | |
| MAPK14 (p38a) | MAPK | CMGC | 3zs5 | A | A | 4-[5-(4-fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-3h-imidazol-4-yl]-pyridine | Human | 4987 | |
| MAPK14 (p38a) | MAPK | CMGC | 8x3m | A | A | - | Human | 15701 | |
| MAPK14 (p38a) | MAPK | CMGC | 3rin | A | | n-cyclopropyl-4-methyl-3-(2'-oxo-1',2'-dihydrospiro[cyclopentane-1,3'-indol]-6'-yl)benzamide | Human | 5239 | |
| MAPK14 (p38a) | MAPK | CMGC | 1wbv | A | | 3-fluoro-n-1h-indol-5-yl-5-morpholin-4-ylbenzamide | Human | 5148 | |
| MAPK14 (p38a) | MAPK | CMGC | 4f9y | A | A | n,n-dimethyl-6-(naphthalen-1-yl)-5-(pyridin-4-yl)pyridazin-3-amine | Human | 5225 | |
| MAPK14 (p38a) | MAPK | CMGC | 2zb0 | A | B | n-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide | Human | 5147 | |
| MAPK14 (p38a) | MAPK | CMGC | 3nnu | A | A | 2-{3-[(5e)-5-{[(2,3-dichlorophenyl)carbamoyl]imino}-3-thiophen-2-yl-2,5-dihydro-1h-pyrazol-1-yl]phenyl}acetamide | Human | 5094 | |
| MAPK14 (p38a) | MAPK | CMGC | 3zya | A | A | 2-amino-phenylamino-dibenzosuberone | Human | 5105 | |
| MAPK14 (p38a) | MAPK | CMGC | 4eh7 | A | B | (3-phenoxyphenyl)methanol | Human | 5020 | |
| MAPK14 (p38a) | MAPK | CMGC | 3iw6 | A | A | ethyl 4-[(4-benzylpiperazin-1-yl)carbonyl]-1-ethyl-3,5-dimethyl-1h-pyrrole-2-carboxylate | Human | 4990 | |
| MAPK14 (p38a) | MAPK | CMGC | 1w7h | A | | 3-(benzyloxy)pyridin-2-amine | Human | 5023 | |
| MAPK14 (p38a) | MAPK | CMGC | 2okr | D | | - | Human | 5100 | |
| MAPK14 (p38a) | MAPK | CMGC | 9cj2 | A | B | - | Human | 15702 | |
| MAPK14 (p38a) | MAPK | CMGC | 4aa5 | A | | n-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxidanylidene-quinazolin-3-yl]benzamide | Human | 5206 | |
| MAPK14 (p38a) | MAPK | CMGC | 4fa2 | A | B | trans-4-[4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)-1h-imidazol-1-yl]cyclohexanol | Human | 5145 | |
| MAPK14 (p38a) | MAPK | CMGC | 6hwv | A | B | - | Human | 11250 | |
| MAPK14 (p38a) | MAPK | CMGC | 5n66 | A | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 8524 | |
| MAPK14 (p38a) | MAPK | CMGC | 2lgc | A | 1 | - | Human | 5021 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gcu | A | B | 1-{3-[(6-aminoquinazolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]urea | Human | 5162 | |
| MAPK14 (p38a) | MAPK | CMGC | 6m95 | A | | (4-benzylpiperidin-1-yl)[2-methoxy-4-(methylsulfanyl)phenyl]methanone | Human | 11252 | |
| MAPK14 (p38a) | MAPK | CMGC | 4eh8 | A | B | [3-(benzyloxy)phenyl]methanol | Human | 5014 | |
| MAPK14 (p38a) | MAPK | CMGC | 2lgc | A | 10 | - | Human | 5063 | |
| MAPK14 (p38a) | MAPK | CMGC | 2zb0 | A | A | n-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide | Human | 5099 | |
| MAPK14 (p38a) | MAPK | CMGC | 6anl | A | B | tak-715 | Human | 9518 | |
| MAPK14 (p38a) | MAPK | CMGC | 3ds6 | D | | n-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide | Human | 5123 | |
| MAPK14 (p38a) | MAPK | CMGC | 5ml5 | A | | 3-(2,5-dimethoxyphenyl)-~{n}-[4-[4-(4-fluorophenyl)-2-methylsulfanyl-1~{h}-imidazol-5-yl]pyridin-2-yl]propanamide | Human | 7544 | |
| MAPK14 (p38a) | MAPK | CMGC | 2rg6 | A | | 4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methyl-n-[(1s)-1-phenylethyl]pyrrolo[2,1-f][1,2,4]triazine-6-carboxamide | Human | 5228 | |
| MAPK14 (p38a) | MAPK | CMGC | 9cj4 | A | A | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 15703 | |
| MAPK14 (p38a) | MAPK | CMGC | 3ha8 | A | A | n~2~-{4-[6-(3,4-dihydroquinolin-1(2h)-ylcarbonyl)-1h-benzimidazol-1-yl]-6-ethoxy-1,3,5-triazin-2-yl}-3-(2,2-dimethyl-4h-1,3-benzodioxin-6-yl)-n-methyl-l-alaninamide | Human | 5253 | |
| MAPK14 (p38a) | MAPK | CMGC | 2lgc | A | 6 | - | Human | 5219 | |
| MAPK14 (p38a) | MAPK | CMGC | 3e93 | A | A | 4-methyl-n-(3-morpholin-4-ylphenyl)-3-(3-piperidin-4-yl-1,2-benzisoxazol-6-yl)benzamide | Human | 5241 | |
| MAPK14 (p38a) | MAPK | CMGC | 9cj4 | A | B | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 15704 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gcs | A | B | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 5052 | |
| MAPK14 (p38a) | MAPK | CMGC | 4eh6 | A | | n-phenylpyridine-3-carboxamide | Human | 5083 | |
| MAPK14 (p38a) | MAPK | CMGC | 3bv2 | A | | 5-methyl-4-[(2-methyl-5-{[(2-morpholin-4-ylpyridin-4-yl)carbonyl]amino}phenyl)amino]-n-(1-phenylethenyl)pyrrolo[2,1-f][1,2,4]triazine-6-carboxamide | Human | 5191 | |
| MAPK14 (p38a) | MAPK | CMGC | 8x3m | A | B | - | Human | 15705 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hll | A | B | 3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1(2h)-yl}-n,4-dimethylbenzamide | Human | 5104 | |
| MAPK14 (p38a) | MAPK | CMGC | 3mpt | A | A | n-(furan-2-ylmethyl)-4-[(2-methylphenyl)carbonyl]-1h-pyrrole-2-carboxamide | Human | 5224 | |
| MAPK14 (p38a) | MAPK | CMGC | 4e5b | A | | - | Human | 5221 | |
| MAPK14 (p38a) | MAPK | CMGC | 2lgc | A | 7 | - | Human | 5161 | |
| MAPK14 (p38a) | MAPK | CMGC | 5xyx | A | A | n-(2-chloro-6-fluorobenzyl)-5-(furan-2-yl)-2h-1,2,4-triazol-3-amine | Human | 9519 | |
| MAPK14 (p38a) | MAPK | CMGC | 4f9w | A | A | n,n-dimethyl-6-(naphthalen-2-yl)-5-(pyridin-4-yl)pyridazin-3-amine | Human | 5130 | |
| MAPK14 (p38a) | MAPK | CMGC | 1zz2 | A | | n-[3-(4-fluorophenoxy)phenyl]-4-[(2-hydroxybenzyl)amino]piperidine-1-sulfonamide | Human | 5164 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gcu | B | B | 1-{3-[(6-aminoquinazolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]urea | Human | 5126 | |
| MAPK14 (p38a) | MAPK | CMGC | 3iw8 | A | | 1-{4-[(1s)-1-amino-2-(benzyloxy)ethyl]-1,3-thiazol-2-yl}-3-(3-chloro-4-fluorophenyl)urea | Human | 5181 | |
| MAPK14 (p38a) | MAPK | CMGC | 4ewq | A | B | 3-phenyl-4-(pyridin-4-yl)-6-[4-(pyrimidin-2-yl)piperazin-1-yl]pyridazine | Human | 5245 | |
| MAPK14 (p38a) | MAPK | CMGC | 4eh4 | A | | phenyl(piperidin-1-yl)methanone | Human | 5043 | |
| MAPK14 (p38a) | MAPK | CMGC | 5etf | A | B | - | Human | 7135 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fkl | A | | n-cyclopropyl-4-methyl-3-[8-methyl-7-oxo-2-(tetrahydro-2h-pyran-4-ylamino)-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl]benzamide | Human | 5172 | |
| MAPK14 (p38a) | MAPK | CMGC | 4eh5 | A | | benzyl pyridine-3-carboxylate | Human | 5185 | |
| MAPK14 (p38a) | MAPK | CMGC | 5n67 | A | B | - | Human | 8521 | |
| MAPK14 (p38a) | MAPK | CMGC | 4zth | A | A | 6-chloro-3-phenyl-4-(pyridin-4-yl)pyridazine | Human | 6706 | |
| MAPK14 (p38a) | MAPK | CMGC | 1zyj | A | | 4-phenoxy-n-(pyridin-2-ylmethyl)benzamide | Human | 5058 | |
| MAPK14 (p38a) | MAPK | CMGC | 3fkn | A | | 3-[2-chloro-5-(methylsulfonyl)phenyl]-6-(2,4-difluorophenoxy)-1h-pyrazolo[3,4-d]pyrimidine | Human | 5049 | |
| MAPK14 (p38a) | MAPK | CMGC | 6sfj | A | A | ~{n}-[5-[[(2~{s})-1-azanyl-4-cyclohexyl-1-oxidanylidene-butan-2-yl]carbamoyl]-2-methyl-phenyl]-1-(2-methylphenyl)pyrazole-4-carboxamide | Human | 11614 | |
| MAPK14 (p38a) | MAPK | CMGC | 1ove | A | B | 1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-piperidin-4-yl-3,4-dihydroquinolin-2(1h)-one | Human | 5087 | |
| MAPK14 (p38a) | MAPK | CMGC | 2rg5 | A | | n-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide | Human | 5254 | |
| MAPK14 (p38a) | MAPK | CMGC | 5n65 | A | | 2-phenyl-~{n}4-(2-thiophen-2-ylethyl)quinazoline-4,7-diamine | Human | 8525 | |
| MAPK14 (p38a) | MAPK | CMGC | 4dlj | A | | 2-phenyl-n~4~-(2-phenylethyl)quinazoline-4,7-diamine | Human | 5242 | |
| MAPK14 (p38a) | MAPK | CMGC | 5n63 | A | | - | Human | 8526 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gcp | A | B | 4-[5-(4-fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-3h-imidazol-4-yl]-pyridine | Human | 5157 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hv5 | B | A | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-{3-[(6-nitroquinolin-4-yl)amino]phenyl}urea | Human | 5085 | |
| MAPK14 (p38a) | MAPK | CMGC | 1oz1 | A | B | 3-(4-fluorophenyl)-2-pyridin-4-yl-1h-pyrrolo[3,2-b]pyridin-1-ol | Human | 5261 | |
| MAPK14 (p38a) | MAPK | CMGC | 3zsh | A | B | 2-(6-chloro-5-{[(2r,5s)-4-(4-fluorobenzyl)-2,5-dimethylpiperazin-1-yl]carbonyl}-1-methyl-1h-indol-3-yl)-n,n-dimethyl-2-oxoacetamide | Human | 5118 | |
| MAPK14 (p38a) | MAPK | CMGC | 6ohd | A | A | 3-(3-tert-butyl-2-oxo-2,3-dihydro-1h-imidazo[4,5-b]pyridin-6-yl)-4-methyl-n-(1,2-oxazol-3-yl)benzamide | Human | 11818 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gcv | A | A | 1-{3-[(6-aminoquinazolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(3-methylphenyl)-1h-pyrazol-5-yl]urea | Human | 5088 | |
| MAPK14 (p38a) | MAPK | CMGC | 5n64 | A | | - | Human | 8527 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gcq | A | A | 1-{4-[(6-aminoquinazolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(3-methylphenyl)-1h-pyrazol-5-yl]urea | Human | 5066 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6qal | A | B | 1,1-bis(oxidanylidene)thietan-3-ol | Human | 10981 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6g91 | A | A | 5-chloranyl-~{n}-(oxan-4-yl)pyrimidin-2-amine | Human | 9965 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fmq | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 2619 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4zzo | A | B | n-[2-[[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]amino]phenyl]propanamide | Human | 2606 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6qa4 | A | B | 1~{h}-pyridin-2-one | Human | 11351 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5v60 | A | A | phosphomethylphosphonic acid adenylate ester | Human | 8261 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6gdq | A | B | 4-[5-chloranyl-2-(propan-2-ylamino)pyridin-4-yl]-~{n}-[(1~{s})-1-(3-chlorophenyl)-2-oxidanyl-ethyl]-1~{h}-pyrrole-2-carboxamide | Human | 9973 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6gjd | A | A | cyclooctyl ~{n}-[3-[[4-[5-[[(3~{r})-1-[2-oxidanylidene-2-[4-(4-pyrimidin-2-ylphenyl)piperazin-1-yl]ethyl]pyrrolidin-3-yl]carbonylamino]-1~{h}-indazol-3-yl]pyridin-2-yl]carbonylamino]propyl]carbamate | Human | 10829 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv0 | A | B | n-cyclohexyl-4-[3-(4-fluorophenyl)-1h-pyrazol-4-yl]pyridin-2-amine | Human | 2599 | |
| MAPK14 (p38a) | MAPK | CMGC | 3od6 | X | | - | Human | 5134 | |
| MAPK14 (p38a) | MAPK | CMGC | 5n68 | A | | - | Human | 8522 | |
| MAPK14 (p38a) | MAPK | CMGC | 3zsi | A | A | 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6h-pyrimido[1,6-b]pyridazin-6-one | Human | 5056 | |
| MAPK9 (JNK2) | MAPK | CMGC | 7n8t | A | A | adenosine monophosphate | Human | 14241 | |
| MAPK9 (JNK2) | MAPK | CMGC | 3npc | A | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 1235 | |
| MAPK9 (JNK2) | MAPK | CMGC | 3e7o | B | | n-{3-[5-(1h-1,2,4-triazol-3-yl)-1h-indazol-3-yl]phenyl}furan-2-carboxamide | Human | 1236 | |
| MAPK9 (JNK2) | MAPK | CMGC | 7cml | A | A | - | Human | 12707 | |
| MAPK6 (Erk3) | MAPK | CMGC | 6yky | C | B | 3-(4-methoxyphenyl)-~{n}-[(3~{r})-1-pyridin-4-ylpyrrolidin-3-yl]-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine | Human | 12784 | |
| MAPK6 (Erk3) | MAPK | CMGC | 6yll | B | | - | Human | 12785 | |
| MAPK6 (Erk3) | MAPK | CMGC | 6yky | B | B | 3-(4-methoxyphenyl)-~{n}-[(3~{r})-1-pyridin-4-ylpyrrolidin-3-yl]-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine | Human | 12786 | |
| MAPK6 (Erk3) | MAPK | CMGC | 6yky | C | A | 3-(4-methoxyphenyl)-~{n}-[(3~{r})-1-pyridin-4-ylpyrrolidin-3-yl]-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine | Human | 12787 | |
| MAPK6 (Erk3) | MAPK | CMGC | 6yky | A | A | 3-(4-methoxyphenyl)-~{n}-[(3~{r})-1-pyridin-4-ylpyrrolidin-3-yl]-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine | Human | 12788 | |
| MAPK6 (Erk3) | MAPK | CMGC | 6yky | D | B | 3-(4-methoxyphenyl)-~{n}-[(3~{r})-1-pyridin-4-ylpyrrolidin-3-yl]-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine | Human | 12789 | |
| MAPK6 (Erk3) | MAPK | CMGC | 6yky | A | B | 3-(4-methoxyphenyl)-~{n}-[(3~{r})-1-pyridin-4-ylpyrrolidin-3-yl]-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine | Human | 12790 | |
| MAPK6 (Erk3) | MAPK | CMGC | 7aqb | B | A | - | Human | 12980 | |
| MAPK6 (Erk3) | MAPK | CMGC | 7aqb | A | B | - | Human | 12981 | |
| MAPK3 (Erk1) | MAPK | CMGC | 6ges | A | B | n-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propanamide | Human | 10926 | |
| MAPK3 (Erk1) | MAPK | CMGC | 4qtb | B | B | (3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamide | Human | 1715 | |
| MAPK3 (Erk1) | MAPK | CMGC | 6ges | A | A | n-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propanamide | Human | 10923 | |
| MAPK3 (Erk1) | MAPK | CMGC | 2zoq | B | | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 1712 | |
| MAPK3 (Erk1) | MAPK | CMGC | 9uw3 | B | | phosphoaminophosphonic acid-adenylate ester | Human | 16037 | |
| MAPK3 (Erk1) | MAPK | CMGC | 9uw4 | A | | phosphoaminophosphonic acid-adenylate ester | Human | 16038 | |
| MAPK3 (Erk1) | MAPK | CMGC | 4qtb | A | B | (3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamide | Human | 1713 | |
| MAPK3 (Erk1) | MAPK | CMGC | 4qtb | A | A | (3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamide | Human | 1714 | |
| MAPK3 (Erk1) | MAPK | CMGC | 6ges | B | A | n-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propanamide | Human | 10925 | |
| MAPK3 (Erk1) | MAPK | CMGC | 6ges | B | B | n-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propanamide | Human | 10924 | |
| MAPK12 (p38g) | MAPK | CMGC | 1cm8 | A | | phosphoaminophosphonic acid-adenylate ester | Human | 4625 | |
| MAPK12 (p38g) | MAPK | CMGC | 6una | A | A | - | Human | 11898 | |
| MAPK12 (p38g) | MAPK | CMGC | 6una | B | B | - | Human | 11899 | |
| MAPK12 (p38g) | MAPK | CMGC | 1cm8 | B | | phosphoaminophosphonic acid-adenylate ester | Human | 4626 | |
