| PLK1 | PLK | Other | 4j52 | A | B | 4-{[(7r)-9-cyclopentyl-7-ethenyl-7-fluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5h-pyrimido[4,5-b][1,4]diazepin-2-yl]amino}-3-methoxy-n-(4-methylpiperazin-1-yl)benzamide | Human | 4976 | |
| PLK2 | PLK | Other | 4i5p | A | A | (7r)-8-cyclopentyl-7-ethyl-5-methyl-2-(1h-pyrrol-2-yl)-7,8-dihydropteridin-6(5h)-one | Human | 5559 | |
| PLK2 | PLK | Other | 4i6h | A | A | (7r)-8-cyclopentyl-7-ethyl-5-methyl-2-[2-(1,3-thiazol-4-yl)-1h-imidazol-1-yl]-7,8-dihydropteridin-6(5h)-one | Human | 5558 | |
| PLK2 | PLK | Other | 4i6f | A | A | (7r)-8-cyclopentyl-7-ethyl-5-methyl-2-(2-phenyl-1h-imidazol-1-yl)-7,8-dihydropteridin-6(5h)-one | Human | 5564 | |
| PLK2 | PLK | Other | 4i5p | A | B | (7r)-8-cyclopentyl-7-ethyl-5-methyl-2-(1h-pyrrol-2-yl)-7,8-dihydropteridin-6(5h)-one | Human | 5560 | |
| PLK1 | PLK | Other | 5ta6 | A | B | 4-{[(6r)-7-cyano-5-cyclopentyl-6-ethyl-5,6-dihydroimidazo[1,5-f]pteridin-3-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 7462 | |
| PLK1 | PLK | Other | 2rku | A | A | 4-{[(7r)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 4969 | |
| PLK1 | PLK | Other | 22rd | A | | 1-(2-hydroxyethyl)-8-[[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino]-4,5-dihydropyrimido[5,4-g]indazole-3-carboxamide | Human | 15471 | |
| PLK4 | PLK | Other | 3cok | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 1814 | |
| PLK4 | PLK | Other | 3cok | B | B | phosphoaminophosphonic acid-adenylate ester | Human | 1817 | |
| PLK4 | PLK | Other | 3cok | B | A | phosphoaminophosphonic acid-adenylate ester | Human | 1815 | |
| PLK4 | PLK | Other | 4yur | A | | 2-({2-fluoro-4-[(2-fluoro-3-nitrobenzyl)sulfonyl]phenyl}sulfanyl)-5-methoxy-n-(3-methyl-1h-pyrazol-5-yl)-6-(morpholin-4-yl)pyrimidin-4-amine | Human | 1813 | |
| PLK2 | PLK | Other | 4i5m | A | | 4-{[(7r)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 5557 | |
| PLK1 | PLK | Other | 2yac | A | | 1-(2-hydroxyethyl)-8-[[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino]-4,5-dihydropyrimido[5,4-g]indazole-3-carboxamide | Human | 4957 | |
| PLK1 | PLK | Other | 3thb | A | | 9-chloro-2-({5-[3-(dimethylamino)propyl]-2-methylpyridin-3-yl}amino)-5,7-dihydro-6h-pyrimido[5,4-d][1]benzazepine-6-thione | Human | 4968 | |
| PLK1 | PLK | Other | 3fc2 | A | B | n-{trans-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}-4-{[(7r)-7-ethyl-5-methyl-8-(1-methylethyl)-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzamide | Human | 4967 | |
| PLK1 | PLK | Other | 2rku | A | B | 4-{[(7r)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 4966 | |
| PLK1 | PLK | Other | 2owb | A | B | 4-(4-methylpiperazin-1-yl)-n-[5-(2-thienylacetyl)-1,5-dihydropyrrolo[3,4-c]pyrazol-3-yl]benzamide | Human | 4958 | |
| PLK1 | PLK | Other | 4j53 | A | A | 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5h-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 4975 | |
| PLK1 | PLK | Other | 2v5q | B | B | - | Human | 4961 | |
| PLK1 | PLK | Other | 2v5q | A | A | - | Human | 4970 | |
| PLK1 | PLK | Other | 5ta6 | A | C | 4-{[(6r)-7-cyano-5-cyclopentyl-6-ethyl-5,6-dihydroimidazo[1,5-f]pteridin-3-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 7463 | |
| PLK1 | PLK | Other | 3kb7 | A | | 8-{[2-methoxy-5-(4-methylpiperazin-1-yl)phenyl]amino}-1-methyl-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 4962 | |
| PLK1 | PLK | Other | 2owb | A | A | 4-(4-methylpiperazin-1-yl)-n-[5-(2-thienylacetyl)-1,5-dihydropyrrolo[3,4-c]pyrazol-3-yl]benzamide | Human | 4974 | |
| PLK1 | PLK | Other | 2ou7 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 4956 | |
| PLK1 | PLK | Other | 4j53 | A | C | 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5h-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 4963 | |
| PLK1 | PLK | Other | 2ou7 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 4973 | |
| PLK1 | PLK | Other | 4j52 | A | A | 4-{[(7r)-9-cyclopentyl-7-ethenyl-7-fluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5h-pyrimido[4,5-b][1,4]diazepin-2-yl]amino}-3-methoxy-n-(4-methylpiperazin-1-yl)benzamide | Human | 4955 | |
| PLK1 | PLK | Other | 5ta6 | A | A | 4-{[(6r)-7-cyano-5-cyclopentyl-6-ethyl-5,6-dihydroimidazo[1,5-f]pteridin-3-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 7465 | |
| PLK1 | PLK | Other | 4a4o | A | | 1-methyl-2-(2-{[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one | Human | 4965 | |
| PLK3 | PLK | Other | 4b6l | A | | 4-[[(4r)-5-cyclopentyl-4-ethyl-3a,4-dihydro-3h-[1,2,4]triazolo[4,3-f]pteridin-7-yl]amino]-n-cyclopropyl-3-methoxy-benzamide | Human | 3797 | |
| PLK4 | PLK | Other | 4jxf | A | | (1r,2s)-2-{3-[(e)-2-{4-[(dimethylamino)methyl]phenyl}ethenyl]-2h-indazol-6-yl}-5'-methoxyspiro[cyclopropane-1,3'-indol]-2'(1'h)-one | Human | 1816 | |
| PLK4 | PLK | Other | 3cok | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 1818 | |
| PLK1 | PLK | Other | 3fc2 | A | A | n-{trans-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}-4-{[(7r)-7-ethyl-5-methyl-8-(1-methylethyl)-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzamide | Human | 4964 | |
| PLK1 | PLK | Other | 8x72 | A | | phosphoaminophosphonic acid-adenylate ester | Human | 15097 | |
| PLK2 | PLK | Other | 4i6b | A | B | (7r)-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydropteridin-6(5h)-one | Human | 5562 | |
| PLK2 | PLK | Other | 4i6h | A | B | (7r)-8-cyclopentyl-7-ethyl-5-methyl-2-[2-(1,3-thiazol-4-yl)-1h-imidazol-1-yl]-7,8-dihydropteridin-6(5h)-one | Human | 5561 | |
| PLK2 | PLK | Other | 4i6b | A | A | (7r)-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydropteridin-6(5h)-one | Human | 5565 | |
| PLK2 | PLK | Other | 4i6f | A | B | (7r)-8-cyclopentyl-7-ethyl-5-methyl-2-(2-phenyl-1h-imidazol-1-yl)-7,8-dihydropteridin-6(5h)-one | Human | 5563 | |
| PLK1 | PLK | Other | 8bjt | A | | 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-one | Human | 14712 | |
| PLK1 | PLK | Other | 5ta8 | A | A | 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5h-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 7464 | |
| PLK1 | PLK | Other | 2v5q | A | B | - | Human | 4960 | |
| PLK1 | PLK | Other | 2v5q | B | A | - | Human | 4959 | |
| PLK1 | PLK | Other | 4a4l | A | | 1-methyl-5-(2-{[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)-1h-pyrrole-3-carboxamide | Human | 4971 | |
| PLK1 | PLK | Other | 9d0p | A | | 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-one | Human | 15472 | |
| PLK1 | PLK | Other | 4j53 | A | B | 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5h-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 4972 | |
| PLK4 | PLK | Other | 9o63 | A | | 5-cyclopropyl-n~2~-[2,6-difluoro-4-(methanesulfonyl)phenyl]-n~2~-methyl-6-(1-methyl-1h-imidazol-4-yl)-n~4~-(5-methyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | 16032 | |
