| RIPK2 | RIPK | TKL | 8aza | B | | - | Human | 14473 | |
| RIPK2 | RIPK | TKL | 6sze | B | B | 5-amino-1-phenylpyrazole-4-carboxamide | Human | 11758 | |
| RIPK2 | RIPK | TKL | 5w5o | P | | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | 8581 | |
| RIPK3 | RIPK | TKL | 7mon | B | | n-[4-({2-[(cyclopropanecarbonyl)amino]pyridin-4-yl}oxy)-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide | Human | 13979 | |
| RIPK1 | RIPK | TKL | 4itj | A | A | n-[(1s)-1-(2-chloro-6-fluorophenyl)ethyl]-5-cyano-1-methyl-1h-pyrrole-2-carboxamide | Human | 575 | |
| RIPK1 | RIPK | TKL | 4itj | A | B | n-[(1s)-1-(2-chloro-6-fluorophenyl)ethyl]-5-cyano-1-methyl-1h-pyrrole-2-carboxamide | Human | 572 | |
| RIPK1 | RIPK | TKL | 4itj | B | B | n-[(1s)-1-(2-chloro-6-fluorophenyl)ethyl]-5-cyano-1-methyl-1h-pyrrole-2-carboxamide | Human | 574 | |
| RIPK2 | RIPK | TKL | 6sze | A | A | 5-amino-1-phenylpyrazole-4-carboxamide | Human | 11759 | |
| RIPK2 | RIPK | TKL | 6s1f | D | | ~{n}-[3-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-5-methoxy-phenyl]methanesulfonamide | Human | 11732 | |
| RIPK2 | RIPK | TKL | 6s1f | B | | ~{n}-[3-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-5-methoxy-phenyl]methanesulfonamide | Human | 11730 | |
| RIPK2 | RIPK | TKL | 6es0 | A | | 2-[2-fluoranyl-4-[[2-fluoranyl-4-[2-(methylcarbamoyl)pyridin-4-yl]oxy-phenyl]carbamoylamino]phenyl]sulfanylethanoic acid | Human | 9574 | |
| RIPK2 | RIPK | TKL | 6szj | A | A | 5-amino-1-~{tert}-butyl-3-(3-methoxyphenyl)pyrazole-4-carboxamide | Human | 11848 | |
| RIPK2 | RIPK | TKL | 5w5o | F | | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | 8582 | |
| RIPK2 | RIPK | TKL | 5j7b | A | | 6-(tert-butylsulfonyl)-n-(5-fluoro-2h-indazol-3-yl)quinolin-4-amine | Human | 6637 | |
| RIPK2 | RIPK | TKL | 6szj | B | B | 5-amino-1-~{tert}-butyl-3-(3-methoxyphenyl)pyrazole-4-carboxamide | Human | 11851 | |
| RIPK1 | RIPK | TKL | 24ib | A | | methyl (3~{s})-5-methyl-4-oxidanylidene-3-[[3-(phenylmethyl)-1~{h}-1,2,4-triazol-5-yl]carbonylamino]-2,3-dihydro-1,5-benzoxazepine-7-carboxylate | Human | 15844 | |
| RIPK1 | RIPK | TKL | 9gtg | A | | (5r)-5-[(7-chloro-1h-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione | Human | 15845 | |
| RIPK1 | RIPK | TKL | 24ic | A | | (3~{s})-~{n}-(cyclopropylmethyl)-5-methyl-4-oxidanylidene-3-[[5-(phenylmethyl)-4~{h}-1,2,4-triazol-3-yl]carbonylamino]-2,3-dihydro-1,5-benzoxazepine-7-carboxamide | Human | 15846 | |
| RIPK1 | RIPK | TKL | 9q32 | A | | methyl 1-[(2,6-dichlorophenyl)methyl]-1h-pyrazole-3-carboxylate | Human | 15847 | |
| RIPK1 | RIPK | TKL | 9gty | A | | (5r)-5-[(7-chloro-1h-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione | Human | 15848 | |
| RIPK2 | RIPK | TKL | 6rn8 | B | | 2-[4-(1,3-benzothiazol-5-ylamino)-6-~{tert}-butylsulfonyl-quinazolin-7-yl]oxyethyl dihydrogen phosphate | Human | 11431 | |
| RIPK2 | RIPK | TKL | 6ul8 | A | A | (5s,6s,8r)-2-(1,3-benzothiazol-5-yl)-6-hydroxy-4,5,6,7,8,9-hexahydro-5,8-methanopyrazolo[1,5-a][1,3]diazocine-3-carboxamide | Human | 11847 | |
| RIPK2 | RIPK | TKL | 6ul8 | A | B | (5s,6s,8r)-2-(1,3-benzothiazol-5-yl)-6-hydroxy-4,5,6,7,8,9-hexahydro-5,8-methanopyrazolo[1,5-a][1,3]diazocine-3-carboxamide | Human | 11849 | |
| RIPK2 | RIPK | TKL | 4c8b | B | | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | 1253 | |
| RIPK3 | RIPK | TKL | 9lfu | A | | 2-cyclopentyl-~{n}-(6-propan-2-ylsulfonylquinolin-4-yl)-1,3-benzothiazol-5-amine | Human | 16128 | |
| RIPK1 | RIPK | TKL | 5tx5 | A | A | gsk2982772 | Human | 8214 | |
| RIPK1 | RIPK | TKL | 4neu | B | A | 1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea | Human | 568 | |
| RIPK1 | RIPK | TKL | 6nw2 | A | B | (5r)-5-methyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2h-indazole-3-carboxamide | Human | 11041 | |
| RIPK1 | RIPK | TKL | 6r5f | B | | [(5~{s})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]-[1-(5-methyl-1,3,4-oxadiazol-2-yl)piperidin-4-yl]methanone | Human | 11044 | |
| RIPK1 | RIPK | TKL | 5tx5 | A | B | gsk2982772 | Human | 8217 | |
| RIPK1 | RIPK | TKL | 6nyh | B | | (5s)-n-[(3s)-7-methoxy-1-methyl-2-oxo-2,3,4,5-tetrahydro-1h-pyrido[3,4-b]azepin-3-yl]-5-phenyl-6,7-dihydro-5h-pyrrolo[1,2-b][1,2,4]triazole-2-carboxamide | Human | 11056 | |
| RIPK1 | RIPK | TKL | 6ocq | A | A | 1-[(2s)-2-(3-fluorophenyl)pyrrolidin-1-yl]-2,2-dimethylpropan-1-one | Human | 11046 | |
| RIPK1 | RIPK | TKL | 4ith | A | B | (5r)-5-[(7-chloro-1h-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione | Human | 567 | |
| RIPK1 | RIPK | TKL | 4iti | B | B | 1-{(3s,3as)-3-[3-fluoro-4-(trifluoromethoxy)phenyl]-8-methoxy-3,3a,4,5-tetrahydro-2h-benzo[g]indazol-2-yl}-2-hydroxyethanone | Human | 569 | |
| RIPK2 | RIPK | TKL | 5ar4 | B | | 4-[5-(4-fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-3h-imidazol-4-yl]-pyridine | Human | 6187 | |
| RIPK1 | RIPK | TKL | 6c3e | A | A | 2-benzyl-5-nitro-1h-benzimidazole | Human | 9750 | |
| RIPK1 | RIPK | TKL | 7ydx | A | B | 1-methyl-5-[2-(2-methylpropanoylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-n-[(1s)-1-phenylethyl]indole-3-carboxamide | Human | 14710 | |
| RIPK1 | RIPK | TKL | 4ith | B | A | (5r)-5-[(7-chloro-1h-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione | Human | 564 | |
| RIPK1 | RIPK | TKL | 6rln | B | | ~{n}-[(3~{s})-7,9-bis(fluoranyl)-2-oxidanylidene-1,3,4,5-tetrahydro-1-benzazepin-3-yl]-3-(phenylmethyl)-1~{h}-1,2,4-triazole-5-carboxamide | Human | 11382 | |
| RIPK1 | RIPK | TKL | 6r5f | C | | [(5~{s})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]-[1-(5-methyl-1,3,4-oxadiazol-2-yl)piperidin-4-yl]methanone | Human | 11042 | |
| RIPK1 | RIPK | TKL | 6c4d | A | | (3s)-3-(2-benzyl-3-chloro-7-oxo-2,4,5,7-tetrahydro-6h-pyrazolo[3,4-c]pyridin-6-yl)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine-8-carbonitrile | Human | 9754 | |
| RIPK1 | RIPK | TKL | 4iti | B | A | 1-{(3s,3as)-3-[3-fluoro-4-(trifluoromethoxy)phenyl]-8-methoxy-3,3a,4,5-tetrahydro-2h-benzo[g]indazol-2-yl}-2-hydroxyethanone | Human | 562 | |
| RIPK1 | RIPK | TKL | 5tx5 | B | A | gsk2982772 | Human | 8216 | |
| RIPK1 | RIPK | TKL | 6ocq | B | B | 1-[(2s)-2-(3-fluorophenyl)pyrrolidin-1-yl]-2,2-dimethylpropan-1-one | Human | 11045 | |
| RIPK1 | RIPK | TKL | 4ith | B | B | (5r)-5-[(7-chloro-1h-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione | Human | 571 | |
| RIPK1 | RIPK | TKL | 5hx6 | B | | 5-benzyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide | Human | 6418 | |
| RIPK1 | RIPK | TKL | 6c4d | C | | (3s)-3-(2-benzyl-3-chloro-7-oxo-2,4,5,7-tetrahydro-6h-pyrazolo[3,4-c]pyridin-6-yl)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine-8-carbonitrile | Human | 9756 | |
| RIPK1 | RIPK | TKL | 6nw2 | A | A | (5r)-5-methyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2h-indazole-3-carboxamide | Human | 11040 | |
| RIPK1 | RIPK | TKL | 6c3e | B | A | 2-benzyl-5-nitro-1h-benzimidazole | Human | 9755 | |
| RIPK1 | RIPK | TKL | 7fd0 | A | | n-[(3s)-5-methyl-7-[2-(oxan-4-yl)ethynyl]-4-oxidanylidene-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-(phenylmethyl)-4h-1,2,4-triazole-3-carboxamide | Human | 14070 | |
| RIPK1 | RIPK | TKL | 5hx6 | A | | 5-benzyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide | Human | 6417 | |
| RIPK1 | RIPK | TKL | 7xmk | A | | 5-[2-(cyclopropylcarbonylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-n-[(1s)-1-(3-fluorophenyl)ethyl]-1-methyl-indole-3-carboxamide | Human | 14716 | |
| RIPK1 | RIPK | TKL | 4neu | A | B | 1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea | Human | 561 | |
| RIPK1 | RIPK | TKL | 6r5f | D | | [(5~{s})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]-[1-(5-methyl-1,3,4-oxadiazol-2-yl)piperidin-4-yl]methanone | Human | 11037 | |
| RIPK1 | RIPK | TKL | 6c4d | D | | (3s)-3-(2-benzyl-3-chloro-7-oxo-2,4,5,7-tetrahydro-6h-pyrazolo[3,4-c]pyridin-6-yl)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine-8-carbonitrile | Human | 9753 | |
| RIPK1 | RIPK | TKL | 6nw2 | B | A | (5r)-5-methyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2h-indazole-3-carboxamide | Human | 11039 | |
| RIPK1 | RIPK | TKL | 6r5f | A | | [(5~{s})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]-[1-(5-methyl-1,3,4-oxadiazol-2-yl)piperidin-4-yl]methanone | Human | 11038 | |
| RIPK1 | RIPK | TKL | 6hho | B | | 6-[4-[(5~{s})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]carbonylpiperidin-1-yl]pyrimidine-4-carbonitrile | Human | 10784 | |
| RIPK2 | RIPK | TKL | 6es0 | B | | 2-[2-fluoranyl-4-[[2-fluoranyl-4-[2-(methylcarbamoyl)pyridin-4-yl]oxy-phenyl]carbamoylamino]phenyl]sulfanylethanoic acid | Human | 9573 | |
| RIPK2 | RIPK | TKL | 5ar8 | B | | 2,6-bis(fluoranyl)-n-[3-[5-[2-[(3-methylsulfonylphenyl)amino]pyrimidin-4-yl]-2-morpholin-4-yl-1,3-thiazol-4-yl]phenyl]benzenesulfonamide | Human | 6179 | |
| RIPK2 | RIPK | TKL | 5j79 | B | B | 4-methyl-3-{[6-(methylsulfonyl)quinolin-4-yl]amino}phenol | Human | 6635 | |
| RIPK2 | RIPK | TKL | 5ng3 | B | | - | Human | 8170 | |
| RIPK2 | RIPK | TKL | 6rna | A | | 2-[4-(1,3-benzothiazol-5-ylamino)-6-~{tert}-butylsulfonyl-quinazolin-7-yl]oxyethanol | Human | 11433 | |
| RIPK2 | RIPK | TKL | 8x2o | A | | ~{n}-[(1~{r})-4-[4-[(6-fluoranyl-1,3-benzothiazol-5-yl)amino]thieno[2,3-d]pyrimidin-6-yl]cyclohex-3-en-1-yl]cyclopropanecarboxamide | Human | 15543 | |
| RIPK2 | RIPK | TKL | 5ng2 | B | B | staurosporine | Human | 8052 | |
| RIPK2 | RIPK | TKL | 6fu5 | B | | ~{n}-[5-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-2-methoxy-phenyl]propane-1-sulfonamide | Human | 9853 | |
| RIPK2 | RIPK | TKL | 4c8b | A | | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | 1254 | |
| RIPK2 | RIPK | TKL | 5ar4 | A | | 4-[5-(4-fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-3h-imidazol-4-yl]-pyridine | Human | 6180 | |
| RIPK2 | RIPK | TKL | 6rna | B | | 2-[4-(1,3-benzothiazol-5-ylamino)-6-~{tert}-butylsulfonyl-quinazolin-7-yl]oxyethanol | Human | 11432 | |
| RIPK2 | RIPK | TKL | 5w5o | N | | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | 8578 | |
| RIPK2 | RIPK | TKL | 6s1f | A | | ~{n}-[3-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-5-methoxy-phenyl]methanesulfonamide | Human | 11733 | |
| RIPK2 | RIPK | TKL | 5w5o | I | | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | 8590 | |
| RIPK2 | RIPK | TKL | 5ar2 | A | B | - | Human | 6173 | |
| RIPK2 | RIPK | TKL | 6szj | B | A | 5-amino-1-~{tert}-butyl-3-(3-methoxyphenyl)pyrazole-4-carboxamide | Human | 11846 | |
| RIPK2 | RIPK | TKL | 5ng0 | B | A | phosphomethylphosphonic acid adenylate ester | Human | 8057 | |
| RIPK2 | RIPK | TKL | 5ng0 | B | B | phosphomethylphosphonic acid adenylate ester | Human | 8055 | |
| RIPK2 | RIPK | TKL | 5ng2 | A | A | staurosporine | Human | 8050 | |
| RIPK2 | RIPK | TKL | 5w5j | A | | n-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide | Human | 8593 | |
| RIPK2 | RIPK | TKL | 5w5o | L | | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | 8585 | |
| RIPK2 | RIPK | TKL | 5ar7 | A | B | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-pyridin-4-yloxyphenyl)urea | Human | 6182 | |
| RIPK2 | RIPK | TKL | 5w5o | J | | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | 8586 | |
| RIPK2 | RIPK | TKL | 5ar5 | B | B | 2-(2-(4-chlorophenyl)-1h-imidazol-5-yl)-n,1-bis(2-methoxyethyl)-1h-benzo[d]imidazole-5-carboxamide | Human | 6172 | |
| RIPK2 | RIPK | TKL | 6hmx | B | | 6-~{tert}-butylsulfonyl-~{n}-(3,4-dimethyl-1~{h}-pyrazol-5-yl)-7-methoxy-quinolin-4-amine | Human | 10675 | |
| RIPK2 | RIPK | TKL | 5ar5 | A | A | 2-(2-(4-chlorophenyl)-1h-imidazol-5-yl)-n,1-bis(2-methoxyethyl)-1h-benzo[d]imidazole-5-carboxamide | Human | 6189 | |
| RIPK2 | RIPK | TKL | 5ng3 | A | | - | Human | 8169 | |
| RIPK2 | RIPK | TKL | 5ar2 | A | A | - | Human | 6183 | |
| RIPK2 | RIPK | TKL | 6fu5 | A | | ~{n}-[5-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-2-methoxy-phenyl]propane-1-sulfonamide | Human | 9852 | |
| RIPK2 | RIPK | TKL | 5ar7 | B | A | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-pyridin-4-yloxyphenyl)urea | Human | 6178 | |
| RIPK2 | RIPK | TKL | 5w5o | B | | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | 8587 | |
| RIPK2 | RIPK | TKL | 6s1f | C | | ~{n}-[3-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-5-methoxy-phenyl]methanesulfonamide | Human | 11731 | |
| RIPK1 | RIPK | TKL | 4iti | A | B | 1-{(3s,3as)-3-[3-fluoro-4-(trifluoromethoxy)phenyl]-8-methoxy-3,3a,4,5-tetrahydro-2h-benzo[g]indazol-2-yl}-2-hydroxyethanone | Human | 563 | |
| RIPK2 | RIPK | TKL | 5ar5 | A | B | 2-(2-(4-chlorophenyl)-1h-imidazol-5-yl)-n,1-bis(2-methoxyethyl)-1h-benzo[d]imidazole-5-carboxamide | Human | 6175 | |
| RIPK1 | RIPK | TKL | 6c3e | A | B | 2-benzyl-5-nitro-1h-benzimidazole | Human | 9751 | |
| RIPK1 | RIPK | TKL | 4neu | A | A | 1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea | Human | 576 | |
| RIPK1 | RIPK | TKL | 4iti | A | A | 1-{(3s,3as)-3-[3-fluoro-4-(trifluoromethoxy)phenyl]-8-methoxy-3,3a,4,5-tetrahydro-2h-benzo[g]indazol-2-yl}-2-hydroxyethanone | Human | 570 | |
| RIPK1 | RIPK | TKL | 7ydx | A | A | 1-methyl-5-[2-(2-methylpropanoylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-n-[(1s)-1-phenylethyl]indole-3-carboxamide | Human | 14711 | |
| RIPK1 | RIPK | TKL | 8i2n | A | | ~{n}-methyl-1-[4-[[[1-methyl-5-(phenylmethyl)pyrazol-3-yl]carbonylamino]methyl]phenyl]benzimidazole-5-carboxamide | Human | 15186 | |
| RIPK1 | RIPK | TKL | 4neu | B | B | 1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea | Human | 573 | |
| RIPK1 | RIPK | TKL | 6ocq | B | A | 1-[(2s)-2-(3-fluorophenyl)pyrrolidin-1-yl]-2,2-dimethylpropan-1-one | Human | 11048 | |
| RIPK1 | RIPK | TKL | 5tx5 | B | B | gsk2982772 | Human | 8215 | |
| RIPK1 | RIPK | TKL | 6nyh | A | | (5s)-n-[(3s)-7-methoxy-1-methyl-2-oxo-2,3,4,5-tetrahydro-1h-pyrido[3,4-b]azepin-3-yl]-5-phenyl-6,7-dihydro-5h-pyrrolo[1,2-b][1,2,4]triazole-2-carboxamide | Human | 11057 | |
| RIPK1 | RIPK | TKL | 6rln | A | | ~{n}-[(3~{s})-7,9-bis(fluoranyl)-2-oxidanylidene-1,3,4,5-tetrahydro-1-benzazepin-3-yl]-3-(phenylmethyl)-1~{h}-1,2,4-triazole-5-carboxamide | Human | 11383 | |
| RIPK1 | RIPK | TKL | 6c4d | B | | (3s)-3-(2-benzyl-3-chloro-7-oxo-2,4,5,7-tetrahydro-6h-pyrazolo[3,4-c]pyridin-6-yl)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine-8-carbonitrile | Human | 9752 | |
| RIPK1 | RIPK | TKL | 4itj | B | A | n-[(1s)-1-(2-chloro-6-fluorophenyl)ethyl]-5-cyano-1-methyl-1h-pyrrole-2-carboxamide | Human | 565 | |
| RIPK1 | RIPK | TKL | 4ith | A | A | (5r)-5-[(7-chloro-1h-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione | Human | 566 | |
| RIPK1 | RIPK | TKL | 6c3e | B | B | 2-benzyl-5-nitro-1h-benzimidazole | Human | 9757 | |
| RIPK1 | RIPK | TKL | 7fcz | A | | n-[(3s)-7-(2-cyclopropylethynyl)-5-methyl-4-oxidanylidene-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-(phenylmethyl)-4h-1,2,4-triazole-3-carboxamide | Human | 14071 | |
| RIPK1 | RIPK | TKL | 6nw2 | B | B | (5r)-5-methyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2h-indazole-3-carboxamide | Human | 11043 | |
| RIPK1 | RIPK | TKL | 6ocq | A | B | 1-[(2s)-2-(3-fluorophenyl)pyrrolidin-1-yl]-2,2-dimethylpropan-1-one | Human | 11047 | |
| RIPK1 | RIPK | TKL | 6hho | A | | 6-[4-[(5~{s})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]carbonylpiperidin-1-yl]pyrimidine-4-carbonitrile | Human | 10783 | |
| RIPK2 | RIPK | TKL | 5ng3 | D | | - | Human | 8172 | |
| RIPK2 | RIPK | TKL | 5w5j | B | | n-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide | Human | 8591 | |
| RIPK2 | RIPK | TKL | 5ar3 | B | B | phosphomethylphosphonic acid adenylate ester | Human | 6190 | |
| RIPK2 | RIPK | TKL | 5ng2 | B | A | staurosporine | Human | 8053 | |
| RIPK2 | RIPK | TKL | 5w5o | D | | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | 8576 | |
| RIPK2 | RIPK | TKL | 6szj | A | B | 5-amino-1-~{tert}-butyl-3-(3-methoxyphenyl)pyrazole-4-carboxamide | Human | 11853 | |
| RIPK2 | RIPK | TKL | 5w5o | A | | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | 8579 | |
| RIPK2 | RIPK | TKL | 5ng3 | C | | - | Human | 8171 | |
| RIPK2 | RIPK | TKL | 6rn8 | A | | 2-[4-(1,3-benzothiazol-5-ylamino)-6-~{tert}-butylsulfonyl-quinazolin-7-yl]oxyethyl dihydrogen phosphate | Human | 11434 | |
| RIPK2 | RIPK | TKL | 5w5o | C | | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | 8577 | |
| RIPK2 | RIPK | TKL | 5ng0 | A | B | phosphomethylphosphonic acid adenylate ester | Human | 8051 | |
| RIPK2 | RIPK | TKL | 6ul8 | B | B | (5s,6s,8r)-2-(1,3-benzothiazol-5-yl)-6-hydroxy-4,5,6,7,8,9-hexahydro-5,8-methanopyrazolo[1,5-a][1,3]diazocine-3-carboxamide | Human | 11850 | |
| RIPK2 | RIPK | TKL | 5ar5 | B | A | 2-(2-(4-chlorophenyl)-1h-imidazol-5-yl)-n,1-bis(2-methoxyethyl)-1h-benzo[d]imidazole-5-carboxamide | Human | 6171 | |
| RIPK2 | RIPK | TKL | 5j79 | A | B | 4-methyl-3-{[6-(methylsulfonyl)quinolin-4-yl]amino}phenol | Human | 6636 | |
| RIPK2 | RIPK | TKL | 5w5o | G | | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | 8580 | |
| RIPK2 | RIPK | TKL | 6hmx | A | | 6-~{tert}-butylsulfonyl-~{n}-(3,4-dimethyl-1~{h}-pyrazol-5-yl)-7-methoxy-quinolin-4-amine | Human | 10676 | |
| RIPK2 | RIPK | TKL | 5j79 | B | A | 4-methyl-3-{[6-(methylsulfonyl)quinolin-4-yl]amino}phenol | Human | 6633 | |
| RIPK2 | RIPK | TKL | 5ar3 | A | B | phosphomethylphosphonic acid adenylate ester | Human | 6186 | |
| RIPK2 | RIPK | TKL | 5w5o | K | | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | 8583 | |
| RIPK2 | RIPK | TKL | 5w5o | M | | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | 8589 | |
| RIPK2 | RIPK | TKL | 5ng0 | A | A | phosphomethylphosphonic acid adenylate ester | Human | 8054 | |
| RIPK2 | RIPK | TKL | 5ar3 | A | A | phosphomethylphosphonic acid adenylate ester | Human | 6184 | |
| RIPK2 | RIPK | TKL | 5ar7 | B | B | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-pyridin-4-yloxyphenyl)urea | Human | 6188 | |
| RIPK2 | RIPK | TKL | 5w5o | O | | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | 8584 | |
| RIPK2 | RIPK | TKL | 6ul8 | B | A | (5s,6s,8r)-2-(1,3-benzothiazol-5-yl)-6-hydroxy-4,5,6,7,8,9-hexahydro-5,8-methanopyrazolo[1,5-a][1,3]diazocine-3-carboxamide | Human | 11852 | |
| RIPK2 | RIPK | TKL | 5ar3 | B | A | phosphomethylphosphonic acid adenylate ester | Human | 6177 | |
| RIPK2 | RIPK | TKL | 5ar2 | B | A | - | Human | 6185 | |
| RIPK2 | RIPK | TKL | 5j79 | A | A | 4-methyl-3-{[6-(methylsulfonyl)quinolin-4-yl]amino}phenol | Human | 6634 | |
| RIPK2 | RIPK | TKL | 5w5o | H | | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | 8588 | |
| RIPK2 | RIPK | TKL | 5w5o | E | | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | Human | 8592 | |
| RIPK2 | RIPK | TKL | 5j7b | B | | 6-(tert-butylsulfonyl)-n-(5-fluoro-2h-indazol-3-yl)quinolin-4-amine | Human | 6632 | |
| RIPK2 | RIPK | TKL | 5ng2 | A | B | staurosporine | Human | 8056 | |
| RIPK2 | RIPK | TKL | 5ar8 | A | | 2,6-bis(fluoranyl)-n-[3-[5-[2-[(3-methylsulfonylphenyl)amino]pyrimidin-4-yl]-2-morpholin-4-yl-1,3-thiazol-4-yl]phenyl]benzenesulfonamide | Human | 6176 | |
| RIPK2 | RIPK | TKL | 6sze | B | A | 5-amino-1-phenylpyrazole-4-carboxamide | Human | 11760 | |
| RIPK2 | RIPK | TKL | 5ar2 | B | B | - | Human | 6181 | |
| RIPK2 | RIPK | TKL | 5ar7 | A | A | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-pyridin-4-yloxyphenyl)urea | Human | 6174 | |
| RIPK2 | RIPK | TKL | 6sze | A | B | 5-amino-1-phenylpyrazole-4-carboxamide | Human | 11761 | |
| RIPK3 | RIPK | TKL | 7mx3 | A | | 3-(1,3-benzothiazol-5-yl)-7-(1,3-dimethyl-1h-pyrazol-5-yl)thieno[3,2-c]pyridin-4-amine | Human | 13995 | |
