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Search results (53 entries covering 36 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetails File
RPS6KA3 (RSK2)RSKAGC5d9kB(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(3-methylbutyl)-7,8-dihydropteridin-6(5h)-oneHuman5987
RPS6KA3 (RSK2)RSKAGC5d9lAB4,4'-(1h-pyrazole-3,4-diyl)diphenolHuman5989
RPS6KA5 (MSK1)RSKAGC1vzoAA-Human108
RPS6KA2 (RSK1)RSKAGC8xovAphosphoaminophosphonic acid-adenylate esterHuman15216
RPS6KB1 (p70S6K)RSKAGC7n91A4-{[(1s)-1-(3-fluorophenyl)-2-(methylamino)ethyl]amino}quinazoline-8-carboxamideHuman14284
RPS6KA3 (RSK2)RSKAGC4nw5AA7-(2-fluoro-6-methoxyphenyl)-n-(3,4,5-trimethoxyphenyl)-1,3-benzoxazol-2-amineHuman134
RPS6KB1 (p70S6K)RSKAGC7n93AA4-({(1s)-2-(azetidin-1-yl)-1-[4-chloro-3-(trifluoromethyl)phenyl]ethyl}amino)quinazoline-8-carboxamideHuman14285
RPS6KB1 (p70S6K)RSKAGC3a61AstaurosporineHuman1846
RPS6KB1 (p70S6K)RSKAGC4l45A2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1h-benzimidazoleHuman1850
RPS6KB1 (p70S6K)RSKAGC3wf5AB4-[4-(1h-benzimidazol-2-yl)piperidin-1-yl]-1h-pyrazolo[3,4-d]pyrimidineHuman1845
RPS6KB1 (p70S6K)RSKAGC3wf6AB4-[4-(1h-indol-3-yl)-3,6-dihydropyridin-1(2h)-yl]-1h-pyrazolo[3,4-d]pyrimidineHuman1859
RPS6KB1 (p70S6K)RSKAGC3wf7AA1-(9h-purin-6-yl)-n-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamideHuman1854
RPS6KB1 (p70S6K)RSKAGC3wf8A2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl 7,8,9,10-tetrahydro-6h-cyclohepta[b]quinoline-11-carboxylateHuman1848
RPS6KB1 (p70S6K)RSKAGC3a62AstaurosporineHuman1867
RPS6KB1 (p70S6K)RSKAGC4l46A2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1h-benzimidazoleHuman1847
RPS6KB1 (p70S6K)RSKAGC4l3lA2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1h-benzimidazoleHuman1863
RPS6KB1 (p70S6K)RSKAGC4l43A2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1h-benzimidazoleHuman1861
RPS6KB1 (p70S6K)RSKAGC3we4A2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1h-benzimidazoleHuman1860
RPS6KB1 (p70S6K)RSKAGC3wf5AA4-[4-(1h-benzimidazol-2-yl)piperidin-1-yl]-1h-pyrazolo[3,4-d]pyrimidineHuman1857
RPS6KB1 (p70S6K)RSKAGC4rlpA[(amino-kappan)methanethiolato](3-fluoro-9-methoxypyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6h,12h)-dionato-kappa~2~n,n')(n-methyl-1,4,7-trithiecan-9-amine-kappa~3~s~1~,s~4~,s~7~)rutheniumHuman7219
RPS6KA3 (RSK2)RSKAGC8eq5AA2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4h-chromen-3-yl 6-deoxy-alpha-l-mannopyranosideHuman14713
RPS6KA3 (RSK2)RSKAGC4nw6AB7-(1h-benzimidazol-7-yl)-n-(3,4,5-trimethoxyphenyl)-1,3-benzoxazol-2-amineHuman136
RPS6KA3 (RSK2)RSKAGC5d9lAA4,4'-(1h-pyrazole-3,4-diyl)diphenolHuman5986
RPS6KA3 (RSK2)RSKAGC4nw6AA7-(1h-benzimidazol-7-yl)-n-(3,4,5-trimethoxyphenyl)-1,3-benzoxazol-2-amineHuman132
RPS6KA3 (RSK2)RSKAGC4nw5AB7-(2-fluoro-6-methoxyphenyl)-n-(3,4,5-trimethoxyphenyl)-1,3-benzoxazol-2-amineHuman135
RPS6KA3 (RSK2)RSKAGC8r58AA2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4h-chromen-3-yl 6-deoxy-alpha-l-mannopyranosideHuman15478
RPS6KA3 (RSK2)RSKAGC4nusAB2,6-difluoro-4-{4-[4-(4-methylpiperazin-1-yl)phenyl]pyridin-3-yl}phenolHuman131
RPS6KA3 (RSK2)RSKAGC7opoAphosphoaminophosphonic acid-adenylate esterHuman14079
RPS6KA3 (RSK2)RSKAGC8r58AB2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4h-chromen-3-yl 6-deoxy-alpha-l-mannopyranosideHuman15479
RPS6KA3 (RSK2)RSKAGC8eq5AB2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4h-chromen-3-yl 6-deoxy-alpha-l-mannopyranosideHuman14714
RPS6KA3 (RSK2)RSKAGC5d9kA(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(3-methylbutyl)-7,8-dihydropteridin-6(5h)-oneHuman5988
RPS6KA3 (RSK2)RSKAGC4nusAA2,6-difluoro-4-{4-[4-(4-methylpiperazin-1-yl)phenyl]pyridin-3-yl}phenolHuman133
RPS6KA1 (RSK3)RSKAGC2z7qAphosphomethylphosphonic acid adenylate esterHuman2778
RPS6KA1 (RSK3)RSKAGC2z7sA2-({6-[(3-chlorophenyl)amino]-9-isopropyl-9h-purin-2-yl}amino)-3-methylbutan-1-olHuman2776
RPS6KA1 (RSK3)RSKAGC2z7rAstaurosporineHuman2777
RPS6KA5 (MSK1)RSKAGC1vzoAB-Human107
RPS6KA6 (RSK4)RSKAGC6g77Aphosphoaminophosphonic acid-adenylate esterHuman11005
RPS6KA6 (RSK4)RSKAGC6g78Aphosphoaminophosphonic acid-adenylate esterHuman11010
RPS6KA6 (RSK4)RSKAGC6g76Aphosphoaminophosphonic acid-adenylate esterHuman11006
RPS6KA6 (RSK4)RSKAGC6g78Bphosphoaminophosphonic acid-adenylate esterHuman11007
RPS6KA6 (RSK4)RSKAGC6g76Bphosphoaminophosphonic acid-adenylate esterHuman11008
RPS6KA6 (RSK4)RSKAGC6g77Bphosphoaminophosphonic acid-adenylate esterHuman11009
RPS6KB1 (p70S6K)RSKAGC3wf7AB1-(9h-purin-6-yl)-n-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamideHuman1851
RPS6KB1 (p70S6K)RSKAGC4l42A2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1h-benzimidazoleHuman1865
RPS6KB1 (p70S6K)RSKAGC4l3jA2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1h-benzimidazoleHuman1858
RPS6KB1 (p70S6K)RSKAGC7n93AB4-({(1s)-2-(azetidin-1-yl)-1-[4-chloro-3-(trifluoromethyl)phenyl]ethyl}amino)quinazoline-8-carboxamideHuman14283
RPS6KB1 (p70S6K)RSKAGC3wf9A(2s)-1-oxo-1-[(4-sulfamoylphenyl)amino]propan-2-yl (2s)-2-methyl-1,2,3,4-tetrahydroacridine-9-carboxylateHuman1866
RPS6KB1 (p70S6K)RSKAGC4rloA[(amino-kappan)methanethiolato](3-fluoro-9-hydroxypyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6h,12h)-dionato-kappa~2~n,n')(1,4,7-trithionane-kappa~3~s~1~,s~4~,s~7~)rutheniumHuman7218
RPS6KB1 (p70S6K)RSKAGC3a60BstaurosporineHuman1856
RPS6KB1 (p70S6K)RSKAGC3a60AstaurosporineHuman1852
RPS6KB1 (p70S6K)RSKAGC3wf6AA4-[4-(1h-indol-3-yl)-3,6-dihydropyridin-1(2h)-yl]-1h-pyrazolo[3,4-d]pyrimidineHuman1864
RPS6KB1 (p70S6K)RSKAGC4l44A2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1h-benzimidazoleHuman1849
RPS6KB1 (p70S6K)RSKAGC4rloBstaurosporineHuman7220
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