Search results (35 entries covering 17 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
| RPS6KA1-b (RSK3-b) | RSKb | CAMK | 3rny | B | A | - | Human | 5573 | ||
| RPS6KA1-b (RSK3-b) | RSKb | CAMK | 2wnt | A | A | - | Human | 6862 | ||
| RPS6KA1-b (RSK3-b) | RSKb | CAMK | 3rny | A | B | - | Human | 5569 | ||
| RPS6KA1-b (RSK3-b) | RSKb | CAMK | 3rny | B | B | - | Human | 5574 | ||
| RPS6KA1-b (RSK3-b) | RSKb | CAMK | 4nif | A | A | - | Human | 5572 | ||
| RPS6KA1-b (RSK3-b) | RSKb | CAMK | 4nif | A | B | - | Human | 5570 | ||
| RPS6KA1-b (RSK3-b) | RSKb | CAMK | 2wnt | B | B | - | Human | 6861 | ||
| RPS6KA1-b (RSK3-b) | RSKb | CAMK | 4nif | D | A | - | Human | 5571 | ||
| RPS6KA1-b (RSK3-b) | RSKb | CAMK | 2wnt | A | B | - | Human | 6859 | ||
| RPS6KA1-b (RSK3-b) | RSKb | CAMK | 2wnt | B | A | - | Human | 6860 | ||
| RPS6KA5-b (MSK1-b) | RSKb | CAMK | 7up4 | A | A | (5m)-5-(2,5-dichloropyrimidin-4-yl)-5h-pyrrolo[3,2-d]pyrimidine | Human | 14277 | ||
| RPS6KA3-b (RSK2-b) | RSKb | CAMK | 4d9u | A | tert-butyl (2s)-3-[4-amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl]-2-cyanopropanoate | Human | 1499 | |||
| RPS6KA3-b (RSK2-b) | RSKb | CAMK | 4jg8 | A | B | (2s)-2-cyano-n-(1-hydroxy-2-methylpropan-2-yl)-3-[3-(3,4,5-trimethoxyphenyl)-1h-indazol-5-yl]propanamide | Human | 1498 | ||
| RPS6KA3-b (RSK2-b) | RSKb | CAMK | 4jg8 | A | A | (2s)-2-cyano-n-(1-hydroxy-2-methylpropan-2-yl)-3-[3-(3,4,5-trimethoxyphenyl)-1h-indazol-5-yl]propanamide | Human | 1497 | ||
| RPS6KA3-b (RSK2-b) | RSKb | CAMK | 4jg7 | A | A | (2r)-2-cyano-3-[3-(1h-pyrrolo[2,3-b]pyridin-3-ylcarbonyl)phenyl]propanamide | Human | 1496 | ||
| RPS6KA3-b (RSK2-b) | RSKb | CAMK | 4jg7 | A | B | (2r)-2-cyano-3-[3-(1h-pyrrolo[2,3-b]pyridin-3-ylcarbonyl)phenyl]propanamide | Human | 1494 | ||
| RPS6KA3-b (RSK2-b) | RSKb | CAMK | 4jg6 | A | (2s)-2-cyano-3-(1h-indazol-5-yl)propanamide | Human | 1495 | |||
| RPS6KA3-b (RSK2-b) | RSKb | CAMK | 4d9t | A | methyl (2s)-3-{4-amino-7-[(1e)-3-hydroxyprop-1-en-1-yl]-5-(4-methylphenyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl}-2-cyanopropanoate | Human | 1493 | |||
| RPS6KA5-b (MSK1-b) | RSKb | CAMK | 7up7 | A | A | (2s)-2-cyano-n-(1-hydroxy-2-methylpropan-2-yl)-3-[3-(3,4,5-trimethoxyphenyl)-1h-indazol-5-yl]propanamide | Human | 14318 | ||
| RPS6KA2-b (RSK1-b) | RSKb | CAMK | 8wf4 | A | - | Human | 15082 | |||
| RPS6KA5-b (MSK1-b) | RSKb | CAMK | 7up8 | A | A | (5m)-5-(5-bromo-2-chloropyrimidin-4-yl)-5h-pyrrolo[3,2-d]pyrimidine | Human | 14282 | ||
| RPS6KA5-b (MSK1-b) | RSKb | CAMK | 7up6 | A | B | (e)-3-(3-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)-2-cyanoacrylamide bound form | Human | 14354 | ||
| RPS6KA3-b (RSK2-b) | RSKb | CAMK | 8xey | A | - | Human | 15207 | |||
| RPS6KA5-b (MSK1-b) | RSKb | CAMK | 3kn6 | A | - | Human | 4602 | |||
| RPS6KA5-b (MSK1-b) | RSKb | CAMK | 3kn6 | B | - | Human | 4601 | |||
| RPS6KA5-b (MSK1-b) | RSKb | CAMK | 7up7 | A | B | (2s)-2-cyano-n-(1-hydroxy-2-methylpropan-2-yl)-3-[3-(3,4,5-trimethoxyphenyl)-1h-indazol-5-yl]propanamide | Human | 14317 | ||
| RPS6KA5-b (MSK1-b) | RSKb | CAMK | 7up5 | A | B | (2m)-6-chloro-2-(5h-pyrrolo[3,2-d]pyrimidin-5-yl)pyridine-3-carbonitrile | Human | 14278 | ||
| RPS6KA5-b (MSK1-b) | RSKb | CAMK | 3kn5 | B | phosphoaminophosphonic acid-adenylate ester | Human | 4600 | |||
| RPS6KA5-b (MSK1-b) | RSKb | CAMK | 7up4 | A | B | (5m)-5-(2,5-dichloropyrimidin-4-yl)-5h-pyrrolo[3,2-d]pyrimidine | Human | 14279 | ||
| RPS6KA5-b (MSK1-b) | RSKb | CAMK | 7up5 | A | A | (2m)-6-chloro-2-(5h-pyrrolo[3,2-d]pyrimidin-5-yl)pyridine-3-carbonitrile | Human | 14280 | ||
| RPS6KA5-b (MSK1-b) | RSKb | CAMK | 7up6 | A | A | (e)-3-(3-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)-2-cyanoacrylamide bound form | Human | 14353 | ||
| RPS6KA5-b (MSK1-b) | RSKb | CAMK | 7up8 | A | B | (5m)-5-(5-bromo-2-chloropyrimidin-4-yl)-5h-pyrrolo[3,2-d]pyrimidine | Human | 14281 | ||
| RPS6KA5-b (MSK1-b) | RSKb | CAMK | 3kn5 | A | phosphoaminophosphonic acid-adenylate ester | Human | 4603 | |||
| RPS6KA1-b (RSK3-b) | RSKb | CAMK | 3rny | A | A | - | Human | 5568 | ||
| RPS6KA1-b (RSK3-b) | RSKb | CAMK | 4nif | D | B | - | Human | 5575 |