Search results (30 entries covering 14 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
| SRPK1 | SRPK | CMGC | 1wbp | A | adenosine-5'-diphosphate | Human | 119 | |||
| SRPK2 | SRPK | CMGC | 5myv | B | B | 5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide | Human | 7573 | ||
| SRPK2 | SRPK | CMGC | 7zkx | A | B | n-[3-[[[2-(6-chloranyl-5-fluoranyl-1h-benzimidazol-2-yl)pyrimidin-4-yl]amino]methyl]pyridin-2-yl]-n-methyl-methanesulfonamide | Human | 14616 | ||
| SRPK1 | SRPK | CMGC | 3beg | A | phosphoaminophosphonic acid-adenylate ester | Human | 9472 | |||
| SRPK2 | SRPK | CMGC | 7zkx | A | A | n-[3-[[[2-(6-chloranyl-5-fluoranyl-1h-benzimidazol-2-yl)pyrimidin-4-yl]amino]methyl]pyridin-2-yl]-n-methyl-methanesulfonamide | Human | 14617 | ||
| SRPK2 | SRPK | CMGC | 5myv | C | A | 5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide | Human | 7580 | ||
| SRPK2 | SRPK | CMGC | 5myv | C | B | 5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide | Human | 7571 | ||
| SRPK2 | SRPK | CMGC | 5myv | D | A | 5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide | Human | 7578 | ||
| SRPK2 | SRPK | CMGC | 5myv | A | A | 5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide | Human | 7579 | ||
| SRPK2 | SRPK | CMGC | 5myv | D | B | 5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide | Human | 7572 | ||
| SRPK1 | SRPK | CMGC | 6fad | D | - | Human | 11637 | |||
| SRPK1 | SRPK | CMGC | 7zks | A | B | n-[3-[[[2-(6-chloranyl-5-fluoranyl-1h-benzimidazol-2-yl)pyrimidin-4-yl]amino]methyl]pyridin-2-yl]-n-methyl-methanesulfonamide | Human | 14618 | ||
| SRPK1 | SRPK | CMGC | 7pqs | A | B | ~{n}-[3-[[[2-(6-chloranyl-7-fluoranyl-1~{h}-benzimidazol-2-yl)pyrimidin-4-yl]amino]methyl]pyridin-2-yl]-~{n}-methyl-methanesulfonamide | Human | 14015 | ||
| SRPK1 | SRPK | CMGC | 6fad | A | - | Human | 11638 | |||
| SRPK1 | SRPK | CMGC | 7pqs | A | A | ~{n}-[3-[[[2-(6-chloranyl-7-fluoranyl-1~{h}-benzimidazol-2-yl)pyrimidin-4-yl]amino]methyl]pyridin-2-yl]-~{n}-methyl-methanesulfonamide | Human | 14014 | ||
| SRPK1 | SRPK | CMGC | 5xv7 | A | 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5h-benzo[b]carbazole-3-carbonitrile | Human | 9727 | |||
| SRPK2 | SRPK | CMGC | 5myv | B | A | 5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide | Human | 7576 | ||
| SRPK2 | SRPK | CMGC | 2x7g | A | purvalanol b | Human | 1409 | |||
| SRPK1 | SRPK | CMGC | 4wua | A | A | n-[2-(1-piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide | Human | 9471 | ||
| SRPK1 | SRPK | CMGC | 6fad | B | - | Human | 11640 | |||
| SRPK1 | SRPK | CMGC | 4wua | A | B | n-[2-(1-piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide | Human | 9469 | ||
| SRPK1 | SRPK | CMGC | 6fad | C | - | Human | 11639 | |||
| SRPK1 | SRPK | CMGC | 5my8 | A | A | sphinx31 | Human | 9466 | ||
| SRPK1 | SRPK | CMGC | 5my8 | A | B | sphinx31 | Human | 9468 | ||
| SRPK1 | SRPK | CMGC | 7zks | A | A | n-[3-[[[2-(6-chloranyl-5-fluoranyl-1h-benzimidazol-2-yl)pyrimidin-4-yl]amino]methyl]pyridin-2-yl]-n-methyl-methanesulfonamide | Human | 14619 | ||
| SRPK1 | SRPK | CMGC | 5mxx | A | A | 5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide | Human | 9470 | ||
| SRPK1 | SRPK | CMGC | 7dd1 | A | - | Human | 13510 | |||
| SRPK1 | SRPK | CMGC | 5mxx | A | B | 5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide | Human | 9467 | ||
| SRPK2 | SRPK | CMGC | 5myv | A | B | 5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide | Human | 7575 | ||
| SRPK1 | SRPK | CMGC | 1wak | A | - | Human | 120 |