| TNIK | STE20 | STE | 2x7f | D | A | 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2h,6h)-dione | Human | 1944 | |
| TNIK | STE20 | STE | 2x7f | E | B | 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2h,6h)-dione | Human | 1949 | |
| TNIK | STE20 | STE | 7xzr | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 14476 | |
| STK24 (MST3) | STE20 | STE | 4o27 | B | | adenosine-5'-diphosphate | Human | 5602 | |
| TNIK | STE20 | STE | 5cwz | B | | - | Human | 6890 | |
| STRADA (STLK5) | STE20 | STE | 2wtk | B | | phosphoaminophosphonic acid-adenylate ester | Human | 3485 | |
| STRADA (STLK5) | STE20 | STE | 2wtk | E | | phosphoaminophosphonic acid-adenylate ester | Human | 3484 | |
| PAK5 | STE20 | STE | 2f57 | A | A | - | Human | 200 | |
| PAK3 | STE20 | STE | 6fd3 | A | A | adenosine-5'-diphosphate | Human | 9462 | |
| PAK4 | STE20 | STE | 4fig | A | | phosphoaminophosphonic acid-adenylate ester | Human | 1392 | |
| PAK4 | STE20 | STE | 4njd | A | A | n-(1h-indazol-5-yl)-n'-[2-(1h-indol-3-yl)ethyl]-6-methoxy-1,3,5-triazine-2,4-diamine | Human | 1382 | |
| OXSR1 (OSR1) | STE20 | STE | 2vwi | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 4839 | |
| STK10 (LOK) | STE20 | STE | 4usd | A | B | 4-{5-(6-methoxynaphthalen-2-yl)-1-methyl-2-[2-methyl-4-(methylsulfonyl)phenyl]-1h-imidazol-4-yl}pyridine | Human | 949 | |
| STK10 (LOK) | STE20 | STE | 6eim | B | B | ~{n}-[5-[4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-1~{h}-benzimidazol-2-yl]furan-2-carboxamide | Human | 8624 | |
| STK24 (MST3) | STE20 | STE | 3ckw | A | A | - | Human | 5580 | |
| STK3 (MST2) | STE20 | STE | 4lg4 | A | B | - | Human | 1438 | |
| MAP4K4 (HGK) | STE20 | STE | 4obp | A | A | 6-(2-fluoropyridin-4-yl)pyrido[3,2-d]pyrimidin-4-amine | Human | 2750 | |
| MAP4K4 (HGK) | STE20 | STE | 4u44 | A | A | 6-phenyl-n-(pyridin-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine | Human | 2752 | |
| STK10 (LOK) | STE20 | STE | 6hxf | D | A | 3-(2-methoxyphenyl)-4-[[4-(phenylcarbonyl)phenyl]amino]pyrrole-2,5-dione | Human | 10650 | |
| STK10 (LOK) | STE20 | STE | 6hxf | B | A | 3-(2-methoxyphenyl)-4-[[4-(phenylcarbonyl)phenyl]amino]pyrrole-2,5-dione | Human | 10651 | |
| TNIK | STE20 | STE | 6ra7 | A | B | 2-[8-azanyl-2-(2-fluoranylpyridin-4-yl)-1,7-naphthyridin-5-yl]propan-2-ol | Human | 11800 | |
| STK10 (LOK) | STE20 | STE | 4aot | B | A | 1-(4-{methyl[2-({4-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]amino}phenyl)-3-{3-[(4-methylpiperazin-1-yl)carbonyl]phenyl}urea | Human | 945 | |
| STK10 (LOK) | STE20 | STE | 5ajq | B | A | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 940 | |
| STK10 (LOK) | STE20 | STE | 4bc6 | A | A | 4-[(3,5-dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 942 | |
| STK10 (LOK) | STE20 | STE | 6eim | A | A | ~{n}-[5-[4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-1~{h}-benzimidazol-2-yl]furan-2-carboxamide | Human | 8626 | |
| STK10 (LOK) | STE20 | STE | 5ajq | B | B | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 948 | |
| STK10 (LOK) | STE20 | STE | 2j7t | A | B | (3z)-n-(3-chlorophenyl)-3-({3,5-dimethyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1h-pyrrol-2-yl}methylene)-n-methyl-2-oxoindoline-5-sulfonamide | Human | 960 | |
| STK10 (LOK) | STE20 | STE | 2j7t | A | A | (3z)-n-(3-chlorophenyl)-3-({3,5-dimethyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1h-pyrrol-2-yl}methylene)-n-methyl-2-oxoindoline-5-sulfonamide | Human | 946 | |
| STK10 (LOK) | STE20 | STE | 5owq | B | A | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | 8387 | |
| STK10 (LOK) | STE20 | STE | 4use | A | A | 4-{5-(6-methoxynaphthalen-2-yl)-1-methyl-2-[2-methyl-4-(methylsulfonyl)phenyl]-1h-imidazol-4-yl}pyridine | Human | 952 | |
| STK10 (LOK) | STE20 | STE | 6hxf | A | B | 3-(2-methoxyphenyl)-4-[[4-(phenylcarbonyl)phenyl]amino]pyrrole-2,5-dione | Human | 10654 | |
| STK10 (LOK) | STE20 | STE | 6hxf | C | A | 3-(2-methoxyphenyl)-4-[[4-(phenylcarbonyl)phenyl]amino]pyrrole-2,5-dione | Human | 10649 | |
| STK10 (LOK) | STE20 | STE | 4equ | B | A | n-{3-[(3-{4-[(4-methoxyphenyl)amino]-1,3,5-triazin-2-yl}pyridin-2-yl)amino]-4-methylphenyl}-3-(trifluoromethyl)benzamide | Human | 941 | |
| STK3 (MST2) | STE20 | STE | 4lgd | C | | phosphoaminophosphonic acid-adenylate ester | Human | 1429 | |
| STK3 (MST2) | STE20 | STE | 4lg4 | B | A | - | Human | 1433 | |
| STK3 (MST2) | STE20 | STE | 4lgd | B | | phosphoaminophosphonic acid-adenylate ester | Human | 1428 | |
| STK10 (LOK) | STE20 | STE | 6i2y | B | | n-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 10788 | |
| STK24 (MST3) | STE20 | STE | 7b33 | A | | 8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[4-[6-[bis(fluoranyl)methyl]pyridin-2-yl]-2-chloranyl-phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one | Human | 13048 | |
| MAP4K1 (HPK1) | STE20 | STE | 8fh4 | A | A | (3p)-3-[6-chloro-4-(9-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)-7h-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile | Human | 14688 | |
| STK24 (MST3) | STE20 | STE | 4qmn | A | B | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 5604 | |
| TNIK | STE20 | STE | 2x7f | C | B | 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2h,6h)-dione | Human | 1948 | |
| STK10 (LOK) | STE20 | STE | 4use | B | A | 4-{5-(6-methoxynaphthalen-2-yl)-1-methyl-2-[2-methyl-4-(methylsulfonyl)phenyl]-1h-imidazol-4-yl}pyridine | Human | 958 | |
| STK10 (LOK) | STE20 | STE | 4bc6 | A | B | 4-[(3,5-dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 961 | |
| STK10 (LOK) | STE20 | STE | 6gtt | A | A | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 10026 | |
| STK10 (LOK) | STE20 | STE | 6eim | A | B | ~{n}-[5-[4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-1~{h}-benzimidazol-2-yl]furan-2-carboxamide | Human | 8625 | |
| STK10 (LOK) | STE20 | STE | 5ajq | A | B | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 955 | |
| STK10 (LOK) | STE20 | STE | 5owr | A | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 8384 | |
| STK24 (MST3) | STE20 | STE | 8bzj | A | B | 8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one | Human | 14583 | |
| STK24 (MST3) | STE20 | STE | 8bzj | A | A | 8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one | Human | 14586 | |
| STK3 (MST2) | STE20 | STE | 4lgd | A | | phosphoaminophosphonic acid-adenylate ester | Human | 1437 | |
| STK24 (MST3) | STE20 | STE | 8bzi | A | B | 8-(4-azanylbutyl)-6-[2,5-bis(fluoranyl)-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one | Human | 14584 | |
| STK10 (LOK) | STE20 | STE | 4usd | B | B | 4-{5-(6-methoxynaphthalen-2-yl)-1-methyl-2-[2-methyl-4-(methylsulfonyl)phenyl]-1h-imidazol-4-yl}pyridine | Human | 956 | |
| STK10 (LOK) | STE20 | STE | 6hxf | A | A | 3-(2-methoxyphenyl)-4-[[4-(phenylcarbonyl)phenyl]amino]pyrrole-2,5-dione | Human | 10656 | |
| STK10 (LOK) | STE20 | STE | 6hxf | D | B | 3-(2-methoxyphenyl)-4-[[4-(phenylcarbonyl)phenyl]amino]pyrrole-2,5-dione | Human | 10653 | |
| MAP4K1 (HPK1) | STE20 | STE | 7r9l | A | | 2-amino-n,n-dimethyl-5-(1h-pyrrolo[2,3-b]pyridin-5-yl)benzamide | Human | 14026 | |
| STK24 (MST3) | STE20 | STE | 3a7j | A | | adenosine-5'-diphosphate | Human | 5594 | |
| STK24 (MST3) | STE20 | STE | 3a7f | A | | - | Human | 5596 | |
| STK24 (MST3) | STE20 | STE | 4qmq | A | A | 1-{2-[5-(2-methoxyethoxy)-1h-benzimidazol-1-yl]quinolin-8-yl}piperidin-4-amine | Human | 5607 | |
| STK24 (MST3) | STE20 | STE | 4qmv | A | | n-{2-[(1s,4r)-6-{[4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,2,3,4-tetrahydro-1,4-epiminonaphthalen-9-yl]-2-oxoethyl}acetamide | Human | 5581 | |
| STK24 (MST3) | STE20 | STE | 7b31 | A | A | 1-[(5-azanyl-1,3-dioxan-2-yl)methyl]-3-[2-chloranyl-4-(3-fluoranylpyridin-2-yl)phenyl]-7-(methylamino)-1,6-naphthyridin-2-one | Human | 13045 | |
| PAK4 | STE20 | STE | 7cp3 | A | | [(3r)-3-azanylpiperidin-1-yl]-[1-(2-azanylpyrimidin-4-yl)-6-[2-(1-oxidanylcyclohexyl)ethynyl]indol-3-yl]methanone | Human | 13849 | |
| MAP4K1 (HPK1) | STE20 | STE | 7r9p | A | | 6-amino-2-fluoro-n,n-dimethyl-3-(4'-methylspiro[cyclopropane-1,3'-pyrrolo[2,3-b]pyridin]-5'-yl)benzamide | Human | 14022 | |
| MAP4K1 (HPK1) | STE20 | STE | 7r9t | A | | 6-amino-3-[(1s,3r)-4'-chloro-3-hydroxy-1',2'-dihydrospiro[cyclopentane-1,3'-pyrrolo[2,3-b]pyridin]-5'-yl]-2-fluoro-n,n-dimethylbenzamide | Human | 14024 | |
| PAK4 | STE20 | STE | 7s48 | A | A | - | Human | 14492 | |
| SLK | STE20 | STE | 8bem | A | B | tivozanib | Human | 14486 | |
| PAK6 | STE20 | STE | 4ks7 | A | A | pf-3758309 | Human | 4682 | |
| PAK6 | STE20 | STE | 4ks7 | A | B | pf-3758309 | Human | 4681 | |
| SLK | STE20 | STE | 4usf | B | B | 4-[4-(6-methoxynaphthalen-2-yl)-1h-imidazol-5-yl]pyridine | Human | 1840 | |
| STK24 (MST3) | STE20 | STE | 7b34 | A | | 8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[2-chloranyl-4-(3-fluoranyl-6-methyl-pyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one | Human | 13051 | |
| PAK4 | STE20 | STE | 7s48 | A | B | - | Human | 14491 | |
| PAK4 | STE20 | STE | 8yhk | A | | - | Human | 15260 | |
| MAP4K1 (HPK1) | STE20 | STE | 9h8e | A | | 5-(methylamino)-6-(3-methylimidazo[4,5-c]pyridin-7-yl)-3-[(4-morpholin-4-ylphenyl)amino]pyrazine-2-carboxamide | Human | 15776 | |
| MAP4K1 (HPK1) | STE20 | STE | 9czx | A | | 4-[(1r)-1-aminopropyl]-2-{6-[(4s,5s)-5-methyl-6,7-dihydro-5h-pyrrolo[2,1-c][1,2,4]triazol-3-yl]pyridin-2-yl}-6-[(2r)-2-methylpyrrolidin-1-yl]-2,3-dihydro-1h-pyrrolo[3,4-c]pyridin-1-one | Human | 15777 | |
| MAP4K1 (HPK1) | STE20 | STE | 9nc2 | A | B | n-{2-(3,3-difluoropyrrolidin-1-yl)-6-[(3r)-pyrrolidin-3-yl]pyrimidin-4-yl}-1-(propan-2-yl)-1h-pyrazolo[4,3-c]pyridin-6-amine | Human | 15775 | |
| MAP4K1 (HPK1) | STE20 | STE | 9nc2 | A | A | n-{2-(3,3-difluoropyrrolidin-1-yl)-6-[(3r)-pyrrolidin-3-yl]pyrimidin-4-yl}-1-(propan-2-yl)-1h-pyrazolo[4,3-c]pyridin-6-amine | Human | 15778 | |
| MAP4K1 (HPK1) | STE20 | STE | 9h8d | A | | 6-(1-methylbenzimidazol-4-yl)-3-[(4-morpholin-4-ylphenyl)amino]pyrazine-2-carboxamide | Human | 15785 | |
| MAP4K1 (HPK1) | STE20 | STE | 9d00 | A | | 4-[(1r)-1-aminopropyl]-6-methoxy-2-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}-2,3-dihydro-1h-isoindol-1-one | Human | 15784 | |
| PAK2 | STE20 | STE | 9ws2 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 15811 | |
| PAK2 | STE20 | STE | 9ws3 | A | A | - | Human | 15812 | |
| PAK2 | STE20 | STE | 9lbg | A | | - | Human | 15810 | |
| PAK2 | STE20 | STE | 9ws5 | A | | - | Human | 15813 | |
| PAK2 | STE20 | STE | 9ws2 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 15809 | |
| TNIK | STE20 | STE | 9xw0 | A | A | - | Human | 15837 | |
| TNIK | STE20 | STE | 9xw0 | A | B | - | Human | 15838 | |
| PAK6 | STE20 | STE | 2c30 | A | A | - | Human | 4679 | |
| PAK6 | STE20 | STE | 4ks8 | A | A | n-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 4683 | |
| PAK6 | STE20 | STE | 4ks8 | A | B | n-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 4680 | |
| PAK6 | STE20 | STE | 2c30 | A | B | - | Human | 4678 | |
| STK4 (MST1) | STE20 | STE | 8a5j | A | B | 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5h-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide | Human | 14291 | |
| SLK | STE20 | STE | 2uv2 | A | A | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 1834 | |
| STK4 (MST1) | STE20 | STE | 9iic | A | | - | Human | 16129 | |
| MAP4K4 (HGK) | STE20 | STE | 8v5i | A | | (3m)-n~6~-(1,4-dimethyl-1h-pyrazol-3-yl)-3-(1-methyl-1h-imidazol-5-yl)-2,7-naphthyridine-1,6-diamine | Human | 16224 | |
| STK24 (MST3) | STE20 | STE | 7b35 | B | | 8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[2-chloranyl-4-(3-methoxy-6-methyl-pyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one | Human | 13046 | |
| STK24 (MST3) | STE20 | STE | 4qmz | A | | n-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 5578 | |
| STK24 (MST3) | STE20 | STE | 4qmx | A | | n-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(tetrahydro-2h-pyran-4-yloxy)quinazolin-4-amine | Human | 5609 | |
| STK24 (MST3) | STE20 | STE | 4qms | A | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 5608 | |
| STK24 (MST3) | STE20 | STE | 4qms | A | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 5590 | |
| STK24 (MST3) | STE20 | STE | 3zhp | C | | - | Human | 5593 | |
| STK24 (MST3) | STE20 | STE | 3zhp | D | | - | Human | 5588 | |
| STK24 (MST3) | STE20 | STE | 4qmt | A | | n-[2-oxo-3-((e)-phenyl{[4-(piperidin-1-ylmethyl)phenyl]imino}methyl)-2,6-dihydro-1h-indol-5-yl]ethanesulfonamide | Human | 5613 | |
| STK24 (MST3) | STE20 | STE | 4qml | A | | phosphoaminophosphonic acid-adenylate ester | Human | 5605 | |
| STK24 (MST3) | STE20 | STE | 3a7g | A | | - | Human | 5612 | |
| STK4 (MST1) | STE20 | STE | 8a5j | A | A | 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5h-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide | Human | 14290 | |
| STK24 (MST3) | STE20 | STE | 4u8z | A | | 3-[4-(morpholin-4-yl)-7h-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile | Human | 5610 | |
| STK24 (MST3) | STE20 | STE | 7b30 | A | | 8-[(trans-5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 13047 | |
| STK24 (MST3) | STE20 | STE | 4qmw | A | A | 1-cyclopentyl-3-(1h-pyrrolo[2,3-b]pyridin-5-yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine | Human | 5577 | |
| STK24 (MST3) | STE20 | STE | 7b32 | A | | 8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-[(2-methoxyphenyl)amino]pyrido[2,3-d]pyrimidin-7-one | Human | 13049 | |
| STK24 (MST3) | STE20 | STE | 7b31 | A | B | 1-[(5-azanyl-1,3-dioxan-2-yl)methyl]-3-[2-chloranyl-4-(3-fluoranylpyridin-2-yl)phenyl]-7-(methylamino)-1,6-naphthyridin-2-one | Human | 13050 | |
| STK24 (MST3) | STE20 | STE | 3a7i | A | | adenine | Human | 5611 | |
| STK24 (MST3) | STE20 | STE | 3ckx | A | | staurosporine | Human | 5599 | |
| STK24 (MST3) | STE20 | STE | 4w8d | A | | 5-(1-methyl-1h-pyrazol-4-yl)-4-(morpholin-4-yl)-7h-pyrrolo[2,3-d]pyrimidine | Human | 5614 | |
| STK24 (MST3) | STE20 | STE | 4qmy | A | | staurosporine | Human | 5592 | |
| PAK4 | STE20 | STE | 4jdh | A | A | - | Human | 1371 | |
| PAK4 | STE20 | STE | 4o0y | A | | 4-[1-(4-amino-1,3,5-triazin-2-yl)-2-(ethylamino)-1h-benzimidazol-6-yl]-2-methylbut-3-yn-2-ol | Human | 1388 | |
| PAK4 | STE20 | STE | 7cmb | A | | 1-(2-azanylpyrimidin-4-yl)-6-[2-(1-oxidanylcyclohexyl)ethynyl]indole-3-carboxamide | Human | 13818 | |
| PAK4 | STE20 | STE | 4jdj | A | A | - | Human | 1400 | |
| PAK4 | STE20 | STE | 2cdz | A | B | n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine | Human | 1374 | |
| PAK4 | STE20 | STE | 4o0x | A | | 1-{[1-(4-amino-1,3,5-triazin-2-yl)-2-methyl-1h-benzimidazol-6-yl]ethynyl}cyclohexanol | Human | 1404 | |
| PAK4 | STE20 | STE | 2q0n | A | A | - | Human | 1393 | |
| PAK4 | STE20 | STE | 5bms | A | | n~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | 1389 | |
| PAK4 | STE20 | STE | 5xva | A | | [6-chloranyl-4-[(5-methyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl]-[(3r)-3-methylpiperazin-1-yl]methanone | Human | 9550 | |
| PAK4 | STE20 | STE | 4xbu | A | | - | Human | 6256 | |
| PAK4 | STE20 | STE | 4fie | A | | phosphoaminophosphonic acid-adenylate ester | Human | 1405 | |
| PAK4 | STE20 | STE | 4fij | A | | - | Human | 1408 | |
| STK24 (MST3) | STE20 | STE | 4qmu | A | A | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 5606 | |
| PAK4 | STE20 | STE | 5upk | B | | phosphoaminophosphonic acid-adenylate ester | Human | 9435 | |
| PAK4 | STE20 | STE | 4jdk | A | A | - | Human | 1375 | |
| PAK4 | STE20 | STE | 4jdk | A | B | - | Human | 1398 | |
| PAK4 | STE20 | STE | 4fif | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 1370 | |
| PAK4 | STE20 | STE | 5zjw | A | A | (3z)-n-[(1s)-2-hydroxy-1-phenylethyl]-3-[(1h-imidazol-2-yl)(phenyl)methylidene]-2-oxo-2,3-dihydro-1h-indole-5-carboxamide | Human | 10999 | |
| PAK4 | STE20 | STE | 4fif | B | B | phosphoaminophosphonic acid-adenylate ester | Human | 1379 | |
| PAK4 | STE20 | STE | 6wlx | A | B | - | Human | 12400 | |
| PAK4 | STE20 | STE | 7s47 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 14493 | |
| PAK4 | STE20 | STE | 4app | A | B | n-[6,6-dimethyl-5-[(2s)-4-methyl-2-(phenylmethyl)piperazin-1-yl]carbonyl-2,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-phenoxy-benzamide | Human | 1390 | |
| PAK4 | STE20 | STE | 2cdz | A | A | n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine | Human | 1378 | |
| TAOK3 (TAO3) | STE20 | STE | 6bdn | A | B | adenosine-5'-diphosphate | Human | 11003 | |
| TAOK3 (TAO3) | STE20 | STE | 6bdn | A | A | adenosine-5'-diphosphate | Human | 11004 | |
| PAK4 | STE20 | STE | 4fie | B | | phosphoaminophosphonic acid-adenylate ester | Human | 1372 | |
| STK24 (MST3) | STE20 | STE | 8qlt | A | B | 8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-[3-(2-oxidanylidenepyrrolidin-1-yl)propylamino]pyrido[2,3-d]pyrimidin-7-one | Human | 14869 | |
| STK24 (MST3) | STE20 | STE | 8qlq | A | A | macrocyclic inhibitor | Human | 14873 | |
| STK24 (MST3) | STE20 | STE | 8qlt | A | A | 8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-[3-(2-oxidanylidenepyrrolidin-1-yl)propylamino]pyrido[2,3-d]pyrimidin-7-one | Human | 14874 | |
| STK24 (MST3) | STE20 | STE | 8qlr | A | | 8-(4-azanylbutyl)-2-[1,3-bis(oxidanyl)propan-2-ylamino]-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]pyrido[2,3-d]pyrimidin-7-one | Human | 14875 | |
| STK24 (MST3) | STE20 | STE | 8qls | A | B | 8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-(3-morpholin-4-ylpropylamino)pyrido[2,3-d]pyrimidin-7-one | Human | 14876 | |
| TNIK | STE20 | STE | 5ax9 | B | | 4-methoxy-3-[2-[(3-methoxy-4-morpholin-4-yl-phenyl)amino]pyridin-4-yl]benzenecarbonitrile | Human | 6892 | |
| SLK | STE20 | STE | 4usf | A | B | 4-[4-(6-methoxynaphthalen-2-yl)-1h-imidazol-5-yl]pyridine | Human | 1832 | |
| TNIK | STE20 | STE | 2x7f | D | B | 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2h,6h)-dione | Human | 1945 | |
| OXSR1 (OSR1) | STE20 | STE | 2vwi | C | B | phosphoaminophosphonic acid-adenylate ester | Human | 4844 | |
| OXSR1 (OSR1) | STE20 | STE | 3dak | A | | phosphoaminophosphonic acid-adenylate ester | Human | 4834 | |
| OXSR1 (OSR1) | STE20 | STE | 2vwi | C | A | phosphoaminophosphonic acid-adenylate ester | Human | 4838 | |
| STK24 (MST3) | STE20 | STE | 4qmo | A | A | (8z)-8-(1h-imidazol-5-ylmethylidene)-6,8-dihydro-7h-[1,3]thiazolo[5,4-e]indol-7-one | Human | 5585 | |
| STK24 (MST3) | STE20 | STE | 4qna | A | | 2-(4,6-diamino-1,3,5-triazin-2-yl)phenol | Human | 5579 | |
| PAK5 | STE20 | STE | 8c12 | A | A | - | Human | 14952 | |
| PAK5 | STE20 | STE | 8c12 | A | B | - | Human | 14953 | |
| PAK5 | STE20 | STE | 2f57 | B | A | n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine | Human | 199 | |
| STK24 (MST3) | STE20 | STE | 4qo9 | A | | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 5586 | |
| STK24 (MST3) | STE20 | STE | 4qmq | A | B | 1-{2-[5-(2-methoxyethoxy)-1h-benzimidazol-1-yl]quinolin-8-yl}piperidin-4-amine | Human | 5595 | |
| STK24 (MST3) | STE20 | STE | 4qmo | A | B | (8z)-8-(1h-imidazol-5-ylmethylidene)-6,8-dihydro-7h-[1,3]thiazolo[5,4-e]indol-7-one | Human | 5597 | |
| STK24 (MST3) | STE20 | STE | 4qo9 | B | | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 5591 | |
| STK24 (MST3) | STE20 | STE | 4qmu | A | B | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 5603 | |
| STK24 (MST3) | STE20 | STE | 8bzi | A | A | 8-(4-azanylbutyl)-6-[2,5-bis(fluoranyl)-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one | Human | 14585 | |
| STK24 (MST3) | STE20 | STE | 3a7h | B | | adenosine-5'-triphosphate | Human | 5576 | |
| STK24 (MST3) | STE20 | STE | 4qmn | A | A | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 5587 | |
| STK24 (MST3) | STE20 | STE | 8qls | A | A | 8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-(3-morpholin-4-ylpropylamino)pyrido[2,3-d]pyrimidin-7-one | Human | 14872 | |
| SLK | STE20 | STE | 2jfm | A | B | - | Human | 1841 | |
| MAP4K1 (HPK1) | STE20 | STE | 8fh4 | A | B | (3p)-3-[6-chloro-4-(9-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)-7h-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile | Human | 14690 | |
| STK26 (MST4) | STE20 | STE | 3ggf | B | B | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 1804 | |
| STK3 (MST2) | STE20 | STE | 4lg4 | A | A | - | Human | 1442 | |
| STK3 (MST2) | STE20 | STE | 4lg4 | C | A | - | Human | 1432 | |
| STK3 (MST2) | STE20 | STE | 4lg4 | B | B | - | Human | 1427 | |
| STK3 (MST2) | STE20 | STE | 8a66 | A | B | 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5h-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide | Human | 14324 | |
| STK3 (MST2) | STE20 | STE | 4lg4 | C | B | - | Human | 1440 | |
| MAP4K4 (HGK) | STE20 | STE | 4obq | B | A | - | Human | 2736 | |
| MAP4K4 (HGK) | STE20 | STE | 4u45 | B | B | - | Human | 2756 | |
| MAP4K4 (HGK) | STE20 | STE | 4u45 | B | A | - | Human | 2741 | |
| MAP4K4 (HGK) | STE20 | STE | 4obo | B | B | - | Human | 2748 | |
| MAP4K4 (HGK) | STE20 | STE | 4u44 | B | A | - | Human | 2737 | |
| MAP4K4 (HGK) | STE20 | STE | 4u3z | B | B | - | Human | 6327 | |
| MAP4K4 (HGK) | STE20 | STE | 4rvt | A | B | 3-hexanoyl-4-hydroxy-5-(4-hydroxyphenyl)pyridin-2(1h)-one | Human | 2760 | |
| MAP4K4 (HGK) | STE20 | STE | 5w5q | B | A | - | Human | 10007 | |
| MAP4K4 (HGK) | STE20 | STE | 4zk5 | A | | 8-amino-n-[1-(cyclopropylcarbonyl)azetidin-3-yl]-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide | Human | 6015 | |
| MAP4K4 (HGK) | STE20 | STE | 4u42 | A | B | 6-[(3s)-3-(4-methyl-1h-pyrazol-3-yl)piperidin-1-yl]pyrido[3,2-d]pyrimidin-4-amine | Human | 6337 | |
| MAP4K4 (HGK) | STE20 | STE | 4u3z | B | A | - | Human | 6336 | |
| MAP4K4 (HGK) | STE20 | STE | 4u42 | B | B | 6-[(3s)-3-(4-methyl-1h-pyrazol-3-yl)piperidin-1-yl]pyrido[3,2-d]pyrimidin-4-amine | Human | 6325 | |
| MAP4K4 (HGK) | STE20 | STE | 4u3y | A | A | - | Human | 6339 | |
| MAP4K4 (HGK) | STE20 | STE | 4u3z | A | A | - | Human | 6333 | |
| MAP4K4 (HGK) | STE20 | STE | 5j95 | B | | - | Human | 8000 | |
| MAP4K4 (HGK) | STE20 | STE | 4zp5 | B | | - | Human | 7090 | |
| MAP4K4 (HGK) | STE20 | STE | 4u43 | A | A | n-(pyridin-3-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine | Human | 2763 | |
| STK3 (MST2) | STE20 | STE | 5dh3 | B | B | 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5h-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide | Human | 7030 | |
| STK24 (MST3) | STE20 | STE | 3a7h | A | | adenosine-5'-triphosphate | Human | 5600 | |
| STK24 (MST3) | STE20 | STE | 8qlq | A | B | macrocyclic inhibitor | Human | 14870 | |
| STK24 (MST3) | STE20 | STE | 3ckw | A | B | - | Human | 5601 | |
| STK24 (MST3) | STE20 | STE | 8qls | A | C | 8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-(3-morpholin-4-ylpropylamino)pyrido[2,3-d]pyrimidin-7-one | Human | 14871 | |
| STK24 (MST3) | STE20 | STE | 3a7g | B | | - | Human | 5598 | |
| STK26 (MST4) | STE20 | STE | 4fza | B | | - | Human | 1806 | |
| STK24 (MST3) | STE20 | STE | 4qmw | A | B | 1-cyclopentyl-3-(1h-pyrrolo[2,3-b]pyridin-5-yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine | Human | 5582 | |
| STK26 (MST4) | STE20 | STE | 3ggf | A | B | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 1808 | |
| MAP4K4 (HGK) | STE20 | STE | 4u3y | B | B | - | Human | 6343 | |
| MAP4K4 (HGK) | STE20 | STE | 5di1 | A | | 4-{6-amino-5-[4-(methylsulfonyl)phenyl]pyridin-3-yl}phenol | Human | 6354 | |
| MAP4K4 (HGK) | STE20 | STE | 4u40 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 6329 | |
| STK24 (MST3) | STE20 | STE | 4qmp | A | | 5-amino-3-{[4-(aminosulfonyl)phenyl]amino}-n-(2,6-difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide | Human | 5584 | |
| OXSR1 (OSR1) | STE20 | STE | 2vwi | B | B | phosphoaminophosphonic acid-adenylate ester | Human | 4836 | |
| OXSR1 (OSR1) | STE20 | STE | 2vwi | D | A | phosphoaminophosphonic acid-adenylate ester | Human | 4835 | |
| OXSR1 (OSR1) | STE20 | STE | 2vwi | D | B | phosphoaminophosphonic acid-adenylate ester | Human | 4833 | |
| STK26 (MST4) | STE20 | STE | 7b36 | C | | 8-[(trans-5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 13043 | |
| STK24 (MST3) | STE20 | STE | 7b35 | A | | 8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[2-chloranyl-4-(3-methoxy-6-methyl-pyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one | Human | 13052 | |
| MAP4K3 (KHS2) | STE20 | STE | 5j5t | A | | 5-[2-(piperidin-4-yl)-1,3-thiazol-5-yl]-3-[(pyridin-4-yl)methoxy]pyridin-2-amine | Human | 7133 | |
| STK26 (MST4) | STE20 | STE | 4fzf | B | | 5-amino-3-{[4-(aminosulfonyl)phenyl]amino}-n-(2,6-difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide | Human | 1803 | |
| STK26 (MST4) | STE20 | STE | 3ggf | B | A | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 1805 | |
| STK26 (MST4) | STE20 | STE | 3ggf | A | A | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 1807 | |
| PAK1 | STE20 | STE | 1yhw | A | | - | Human | 160 | |
| PAK1 | STE20 | STE | 3fxz | A | A | octahedral ru-pyridocarbazole | Human | 7198 | |
| PAK1 | STE20 | STE | 4daw | A | B | [1,3-dioxo-6-(pyridin-2-yl-kappan)-2,3-dihydro-1h-isoindol-5-yl-kappac~5~][(thioxomethylidene)azanido-kappan](1,4,7-trithionane-kappa~3~s~1~,s~4~,s~7~)ruthenium | Human | 7199 | |
| PAK1 | STE20 | STE | 4zji | C | B | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | Human | 152 | |
| PAK1 | STE20 | STE | 4o0r | A | | pf-3758309 | Human | 171 | |
| PAK1 | STE20 | STE | 3fxz | A | B | octahedral ru-pyridocarbazole | Human | 7200 | |
| PAK1 | STE20 | STE | 3q4z | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 166 | |
| PAK1 | STE20 | STE | 4zlo | B | B | - | Human | 170 | |
| PAK1 | STE20 | STE | 4zy6 | B | A | n~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | 156 | |
| PAK1 | STE20 | STE | 3q53 | A | | adenosine-5'-triphosphate | Human | 165 | |
| PAK1 | STE20 | STE | 4zjj | D | A | (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide | Human | 169 | |
| PAK1 | STE20 | STE | 8x5z | A | B | - | Human | 15048 | |
| PAK1 | STE20 | STE | 4zy6 | A | B | n~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | 173 | |
| PAK1 | STE20 | STE | 5kbq | B | | - | Human | 7082 | |
| PAK1 | STE20 | STE | 4zy4 | A | | 2-(4-aminopiperidin-1-yl)-n-(5-cyclopropyl-1h-pyrazol-3-yl)thieno[3,2-d]pyrimidin-4-amine | Human | 187 | |
| PAK1 | STE20 | STE | 8x5z | A | A | - | Human | 15049 | |
| PAK1 | STE20 | STE | 4daw | A | A | [1,3-dioxo-6-(pyridin-2-yl-kappan)-2,3-dihydro-1h-isoindol-5-yl-kappac~5~][(thioxomethylidene)azanido-kappan](1,4,7-trithionane-kappa~3~s~1~,s~4~,s~7~)ruthenium | Human | 7201 | |
| PAK1 | STE20 | STE | 4o0t | A | | 1-({1-(2-aminopyrimidin-4-yl)-2-[(2-methoxyethyl)amino]-1h-benzimidazol-6-yl}ethynyl)cyclohexanol | Human | 143 | |
| PAK1 | STE20 | STE | 5dfp | A | B | 6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-{[2-(1-methylpiperidin-4-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 6363 | |
| PAK1 | STE20 | STE | 4zy5 | A | | n~2~-[(trans-4-aminocyclohexyl)methyl]-n~4~-(3-cyclopropyl-1h-pyrazol-5-yl)pyrimidine-2,4-diamine | Human | 155 | |
| PAK1 | STE20 | STE | 4p90 | B | | [2-chloro-5-(hydroxymethyl)phenyl]{5-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]-1h-pyrrolo[2,3-b]pyridin-3-yl}methanone | Human | 151 | |
| PAK1 | STE20 | STE | 5dew | B | | 8-[(trans-4-aminocyclohexyl)methyl]-6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(ethylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 7409 | |
| PAK1 | STE20 | STE | 4zy6 | A | A | n~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | 138 | |
| PAK1 | STE20 | STE | 3q4z | B | B | - | Human | 183 | |
| PAK1 | STE20 | STE | 4zjj | A | A | (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide | Human | 157 | |
| PAK1 | STE20 | STE | 1yhv | A | | - | Human | 177 | |
| PAK1 | STE20 | STE | 4zy5 | B | | n~2~-[(trans-4-aminocyclohexyl)methyl]-n~4~-(3-cyclopropyl-1h-pyrazol-5-yl)pyrimidine-2,4-diamine | Human | 163 | |
| PAK1 | STE20 | STE | 7vto | A | A | 4-[(7-oxo-7h-thiazolo[5,4-e]indol-8-ylmethyl)-amino]-n-pyridin-2-yl-benzenesulfonamide | Human | 14483 | |
| PAK1 | STE20 | STE | 3q52 | A | | - | Human | 146 | |
| PAK1 | STE20 | STE | 4zji | B | A | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | Human | 168 | |
| PAK1 | STE20 | STE | 7vto | A | B | 4-[(7-oxo-7h-thiazolo[5,4-e]indol-8-ylmethyl)-amino]-n-pyridin-2-yl-benzenesulfonamide | Human | 14484 | |
| PAK1 | STE20 | STE | 9nbx | A | | (6m)-8-(3-aminopropyl)-6-(4-butoxy-2-methylphenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 15745 | |
| MAP4K1 (HPK1) | STE20 | STE | 6cqe | B | A | - | Human | 10805 | |
| MAP4K1 (HPK1) | STE20 | STE | 8fko | A | | (3p)-3-{4-[(2s,5r)-5-amino-2-methylpiperidin-1-yl]-6-chloro-7h-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrile | Human | 14689 | |
| MAP4K1 (HPK1) | STE20 | STE | 6nfz | B | | n-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 11074 | |
| MAP4K1 (HPK1) | STE20 | STE | 8cdw | A | B | ~{n}-[4-(1-methylpiperidin-4-yl)phenyl]-7-(1-methylpyrazol-4-yl)quinazolin-2-amine | Human | 14895 | |
| MAP4K1 (HPK1) | STE20 | STE | 7m0k | C | B | 4-anilino-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide | Human | 13474 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l24 | A | B | 6-(2-fluoro-6-methoxyphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]-1h-pyrazolo[4,3-c]pyridine | Human | 13418 | |
| MAP4K1 (HPK1) | STE20 | STE | 7m0l | A | | 4-(2-bromoanilino)-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide | Human | 13475 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l24 | B | B | 6-(2-fluoro-6-methoxyphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]-1h-pyrazolo[4,3-c]pyridine | Human | 13426 | |
| MAP4K1 (HPK1) | STE20 | STE | 6ng0 | B | | n-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 11073 | |
| MAP4K1 (HPK1) | STE20 | STE | 7m0l | C | | 4-(2-bromoanilino)-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide | Human | 13478 | |
| MAP4K1 (HPK1) | STE20 | STE | 7m0k | D | A | 4-anilino-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide | Human | 13479 | |
| MAP4K1 (HPK1) | STE20 | STE | 9czw | A | | 6-(dimethylamino)-4-[(methylamino)methyl]-2-[6-(4-propyl-4h-1,2,4-triazol-3-yl)pyridin-2-yl]-2,3-dihydro-1h-pyrrolo[3,4-c]pyridin-1-one | Human | 15780 | |
| TNIK | STE20 | STE | 5d7a | B | | cis-4-{[2-(1h-benzimidazol-5-ylamino)quinazolin-8-yl]oxy}cyclohexanol | Human | 6964 | |
| TNIK | STE20 | STE | 8wm0 | A | A | adenosine | Human | 15232 | |
| STK24 (MST3) | STE20 | STE | 4qmm | A | | 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1h-benzimidazol-2-yl]-1h-pyrazol-4-yl}urea | Human | 5583 | |
| STK4 (MST1) | STE20 | STE | 8pav | A | B | 1-[3,5-bis(fluoranyl)-4-[[3-(1,3-thiazol-5-yl)-1~{h}-pyrrolo[2,3-b]pyridin-4-yl]oxy]phenyl]-3-(2-methoxyethyl)urea | Human | 15348 | |
| STK4 (MST1) | STE20 | STE | 8pav | A | A | 1-[3,5-bis(fluoranyl)-4-[[3-(1,3-thiazol-5-yl)-1~{h}-pyrrolo[2,3-b]pyridin-4-yl]oxy]phenyl]-3-(2-methoxyethyl)urea | Human | 15349 | |
| STK4 (MST1) | STE20 | STE | 8paw | A | | 1-[3,5-bis(fluoranyl)-4-[[3-(1-propan-2-ylpyrazol-3-yl)-1~{h}-pyrrolo[2,3-b]pyridin-4-yl]oxy]phenyl]-3-(2-methoxyethyl)urea | Human | 15350 | |
| STK10 (LOK) | STE20 | STE | 4use | B | B | 4-{5-(6-methoxynaphthalen-2-yl)-1-methyl-2-[2-methyl-4-(methylsulfonyl)phenyl]-1h-imidazol-4-yl}pyridine | Human | 954 | |
| PAK5 | STE20 | STE | 2f57 | B | B | n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine | Human | 201 | |
| PAK5 | STE20 | STE | 2f57 | A | B | - | Human | 202 | |
| PAK3 | STE20 | STE | 6fd3 | A | B | adenosine-5'-diphosphate | Human | 9463 | |
| PAK4 | STE20 | STE | 4o0v | A | | 1-({1-(2-aminopyrimidin-4-yl)-2-[(2-methoxyethyl)amino]-1h-benzimidazol-6-yl}ethynyl)cyclohexanol | Human | 1386 | |
| PAK4 | STE20 | STE | 2bva | B | | - | Human | 1407 | |
| STK10 (LOK) | STE20 | STE | 6gtt | A | B | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 10025 | |
| STK10 (LOK) | STE20 | STE | 6hxf | B | B | 3-(2-methoxyphenyl)-4-[[4-(phenylcarbonyl)phenyl]amino]pyrrole-2,5-dione | Human | 10652 | |
| STK10 (LOK) | STE20 | STE | 5owq | B | B | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | 8389 | |
| STK10 (LOK) | STE20 | STE | 4aot | B | B | 1-(4-{methyl[2-({4-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]amino}phenyl)-3-{3-[(4-methylpiperazin-1-yl)carbonyl]phenyl}urea | Human | 943 | |
| STK10 (LOK) | STE20 | STE | 4equ | B | B | n-{3-[(3-{4-[(4-methoxyphenyl)amino]-1,3,5-triazin-2-yl}pyridin-2-yl)amino]-4-methylphenyl}-3-(trifluoromethyl)benzamide | Human | 959 | |
| PAK1 | STE20 | STE | 4p90 | A | | [2-chloro-5-(hydroxymethyl)phenyl]{5-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]-1h-pyrrolo[2,3-b]pyridin-3-yl}methanone | Human | 164 | |
| MAP4K4 (HGK) | STE20 | STE | 4u40 | B | B | - | Human | 6331 | |
| OXSR1 (OSR1) | STE20 | STE | 3dak | D | | phosphoaminophosphonic acid-adenylate ester | Human | 4840 | |
| OXSR1 (OSR1) | STE20 | STE | 3dak | B | | phosphoaminophosphonic acid-adenylate ester | Human | 4841 | |
| OXSR1 (OSR1) | STE20 | STE | 2vwi | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 4842 | |
| OXSR1 (OSR1) | STE20 | STE | 2vwi | B | A | phosphoaminophosphonic acid-adenylate ester | Human | 4843 | |
| OXSR1 (OSR1) | STE20 | STE | 3dak | C | | phosphoaminophosphonic acid-adenylate ester | Human | 4837 | |
| STK26 (MST4) | STE20 | STE | 7b36 | A | | 8-[(trans-5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 13044 | |
| STK26 (MST4) | STE20 | STE | 4fzd | B | | - | Human | 1809 | |
| STK24 (MST3) | STE20 | STE | 4w8e | A | | 3-{4-[(2r)-2-(5-methyl-1,2,4-oxadiazol-3-yl)morpholin-4-yl]-7h-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrile | Human | 5589 | |
| SLK | STE20 | STE | 4usf | A | A | 4-[4-(6-methoxynaphthalen-2-yl)-1h-imidazol-5-yl]pyridine | Human | 1839 | |
| SLK | STE20 | STE | 4usf | B | A | 4-[4-(6-methoxynaphthalen-2-yl)-1h-imidazol-5-yl]pyridine | Human | 1835 | |
| SLK | STE20 | STE | 2jfm | A | A | - | Human | 1836 | |
| SLK | STE20 | STE | 2jfl | A | | 5-amino-3-{[4-(aminosulfonyl)phenyl]amino}-n-(2,6-difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide | Human | 1838 | |
| SLK | STE20 | STE | 6hvd | A | A | 3-(1,3-benzothiazol-2-ylamino)-4-(2-methoxyphenyl)pyrrole-2,5-dione | Human | 10625 | |
| SLK | STE20 | STE | 6hvd | A | B | 3-(1,3-benzothiazol-2-ylamino)-4-(2-methoxyphenyl)pyrrole-2,5-dione | Human | 10624 | |
| SLK | STE20 | STE | 2j51 | A | | 5-amino-3-{[4-(aminosulfonyl)phenyl]amino}-n-(2,6-difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide | Human | 1833 | |
| SLK | STE20 | STE | 8bem | A | A | tivozanib | Human | 14487 | |
| SLK | STE20 | STE | 2uv2 | A | B | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 1837 | |
| PAK1 | STE20 | STE | 4zji | D | B | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | Human | 150 | |
| PAK1 | STE20 | STE | 5dew | A | | 8-[(trans-4-aminocyclohexyl)methyl]-6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(ethylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 7408 | |
| PAK1 | STE20 | STE | 4zlo | A | A | 2,8-difluoro-11-(4-methylpiperazin-1-yl)-5h-dibenzo[b,e][1,4]diazepine | Human | 142 | |
| PAK1 | STE20 | STE | 9n4u | A | | (3m)-3-[(4p)-2-chloro-4-(6-methylpyridin-2-yl)phenyl]-1-{2-[2-(dimethylamino)ethoxy]ethyl}-1,6-naphthyridin-2(1h)-one | Human | 15744 | |
| PAK1 | STE20 | STE | 4zjj | A | B | (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide | Human | 153 | |
| PAK1 | STE20 | STE | 6b16 | A | | n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)-n~2~-[(1s)-1-(1h-pyrrolo[3,2-b]pyridin-5-yl)ethyl]pyrimidine-2,4-diamine | Human | 8574 | |
| PAK1 | STE20 | STE | 4zji | D | A | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | Human | 139 | |
| PAK1 | STE20 | STE | 4zji | B | B | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | Human | 185 | |
| PAK1 | STE20 | STE | 4zlo | A | B | 2,8-difluoro-11-(4-methylpiperazin-1-yl)-5h-dibenzo[b,e][1,4]diazepine | Human | 181 | |
| PAK1 | STE20 | STE | 4zji | C | A | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | Human | 167 | |
| PAK1 | STE20 | STE | 5dey | A | | 8-[(trans-5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 6364 | |
| PAK1 | STE20 | STE | 4zji | A | B | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | Human | 175 | |
| PAK1 | STE20 | STE | 3q4z | B | A | - | Human | 144 | |
| PAK1 | STE20 | STE | 5ime | A | | 8-(3-aminopropyl)-6-[2-chloro-4-(3-methyl-2-oxopyrazin-1(2h)-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 6644 | |
| PAK1 | STE20 | STE | 4zji | A | A | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | Human | 159 | |
| PAK1 | STE20 | STE | 4zjj | B | A | (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide | Human | 176 | |
| PAK1 | STE20 | STE | 1f3m | D | | - | Human | 158 | |
| PAK1 | STE20 | STE | 5dfp | A | A | 6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-{[2-(1-methylpiperidin-4-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 6366 | |
| PAK1 | STE20 | STE | 5kbr | A | | (4-chlorophenyl)-[5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]methanone | Human | 7080 | |
| PAK1 | STE20 | STE | 4zjj | B | B | (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide | Human | 137 | |
| PAK1 | STE20 | STE | 4eqc | A | B | 6-[2-chloro-4-(1,3-thiazol-5-yl)phenyl]-8-ethyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 147 | |
| PAK1 | STE20 | STE | 4zy4 | B | | 2-(4-aminopiperidin-1-yl)-n-(5-cyclopropyl-1h-pyrazol-3-yl)thieno[3,2-d]pyrimidin-4-amine | Human | 154 | |
| PAK1 | STE20 | STE | 1f3m | C | | - | Human | 161 | |
| PAK1 | STE20 | STE | 5dey | B | | 8-[(trans-5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 6365 | |
| PAK1 | STE20 | STE | 5kbr | B | | (4-chlorophenyl)-[5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]methanone | Human | 7079 | |
| PAK1 | STE20 | STE | 6b16 | B | | n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)-n~2~-[(1s)-1-(1h-pyrrolo[3,2-b]pyridin-5-yl)ethyl]pyrimidine-2,4-diamine | Human | 8575 | |
| PAK1 | STE20 | STE | 4o0t | B | | - | Human | 141 | |
| PAK1 | STE20 | STE | 5ime | B | | 8-(3-aminopropyl)-6-[2-chloro-4-(3-methyl-2-oxopyrazin-1(2h)-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 6643 | |
| PAK1 | STE20 | STE | 3q4z | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 174 | |
| PAK1 | STE20 | STE | 3fy0 | A | | ruthenium pyridocarbazole | Human | 7202 | |
| PAK1 | STE20 | STE | 4zjj | D | B | (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide | Human | 162 | |
| PAK1 | STE20 | STE | 4zy6 | B | B | n~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | 184 | |
| PAK1 | STE20 | STE | 2hy8 | 1 | | (5s,6r,7r,9r)-12-hydroxy-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9-tetrahydro-5h,14h-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-one | Human | 172 | |
| PAK1 | STE20 | STE | 4zlo | B | A | - | Human | 188 | |
| PAK1 | STE20 | STE | 4zjj | C | A | (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide | Human | 182 | |
| PAK1 | STE20 | STE | 5kbq | A | | [4-methyl-3-[methyl-[2-[(3-methylsulfonyl-5-morpholin-4-yl-phenyl)amino]pyrimidin-4-yl]amino]phenyl]methanol | Human | 7081 | |
| PAK1 | STE20 | STE | 4eqc | A | A | 6-[2-chloro-4-(1,3-thiazol-5-yl)phenyl]-8-ethyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 180 | |
| PAK1 | STE20 | STE | 4o0r | B | | - | Human | 145 | |
| PAK1 | STE20 | STE | 4zjj | C | B | (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide | Human | 178 | |
| MAP4K1 (HPK1) | STE20 | STE | 7m0l | B | | 4-(2-bromoanilino)-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide | Human | 13466 | |
| MAP4K1 (HPK1) | STE20 | STE | 7m0m | B | A | 4-[2-fluoro-6-(trifluoromethyl)anilino]-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide | Human | 13467 | |
| MAP4K1 (HPK1) | STE20 | STE | 6cqe | A | A | - | Human | 10802 | |
| MAP4K1 (HPK1) | STE20 | STE | 7m0l | D | | 4-(2-bromoanilino)-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide | Human | 13468 | |
| MAP4K1 (HPK1) | STE20 | STE | 7r9n | A | B | n-{2-(3,3-difluoropyrrolidin-1-yl)-6-[(3r)-pyrrolidin-3-yl]pyrimidin-4-yl}-1-(propan-2-yl)-1h-pyrazolo[4,3-c]pyridin-6-amine | Human | 14023 | |
| MAP4K1 (HPK1) | STE20 | STE | 7m0m | A | A | 4-[2-fluoro-6-(trifluoromethyl)anilino]-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide | Human | 13469 | |
| MAP4K1 (HPK1) | STE20 | STE | 7kac | B | | 5-{[4-{[(1s)-2-hydroxy-1-phenylethyl]amino}-5-(1,3,4-oxadiazol-2-yl)pyrimidin-2-yl]amino}-3,3-dimethyl-2-benzofuran-1(3h)-one | Human | 13230 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l25 | B | A | 6-(2-fluoro-6-methoxyphenyl)-1-[6-(4-methylpiperazin-1-yl)pyridin-2-yl]-1h-pyrazolo[4,3-c]pyridine | Human | 13413 | |
| MAP4K1 (HPK1) | STE20 | STE | 6cqd | B | | phosphoaminophosphonic acid-adenylate ester | Human | 10801 | |
| MAP4K1 (HPK1) | STE20 | STE | 7m0k | B | B | 4-anilino-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide | Human | 13470 | |
| MAP4K1 (HPK1) | STE20 | STE | 6cqf | A | | n-{2-(3,3-difluoropyrrolidin-1-yl)-6-[(3r)-pyrrolidin-3-yl]pyrimidin-4-yl}-1-(propan-2-yl)-1h-pyrazolo[4,3-c]pyridin-6-amine | Human | 10806 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l26 | B | B | 6-(2-fluoro-6-methylphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]-1h-indazole-5-carbonitrile | Human | 13414 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l24 | D | A | 6-(2-fluoro-6-methoxyphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]-1h-pyrazolo[4,3-c]pyridine | Human | 13415 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l24 | A | A | 6-(2-fluoro-6-methoxyphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]-1h-pyrazolo[4,3-c]pyridine | Human | 13416 | |
| MAP4K1 (HPK1) | STE20 | STE | 7m0k | D | B | 4-anilino-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide | Human | 13471 | |
| MAP4K1 (HPK1) | STE20 | STE | 6cqe | B | B | - | Human | 10800 | |
| MAP4K1 (HPK1) | STE20 | STE | 7m0m | B | B | 4-[2-fluoro-6-(trifluoromethyl)anilino]-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide | Human | 13472 | |
| MAP4K1 (HPK1) | STE20 | STE | 7siu | A | | 6-[(5r)-5-benzamidocyclohex-1-en-1-yl]-3-[(1-methyl-1h-pyrazol-4-yl)amino]pyrazine-2-carboxamide | Human | 14117 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l24 | C | B | 6-(2-fluoro-6-methoxyphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]-1h-pyrazolo[4,3-c]pyridine | Human | 13417 | |
| MAP4K1 (HPK1) | STE20 | STE | 7m0k | C | A | 4-anilino-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide | Human | 13473 | |
| MAP4K1 (HPK1) | STE20 | STE | 6ng0 | A | | n-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 11071 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l26 | C | A | 6-(2-fluoro-6-methylphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]-1h-indazole-5-carbonitrile | Human | 13419 | |
| MAP4K1 (HPK1) | STE20 | STE | 9czt | A | | 4-(aminomethyl)-2-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}-2,3-dihydro-1h-isoindol-1-one | Human | 15783 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l26 | C | B | 6-(2-fluoro-6-methylphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]-1h-indazole-5-carbonitrile | Human | 13420 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l24 | D | B | 6-(2-fluoro-6-methoxyphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]-1h-pyrazolo[4,3-c]pyridine | Human | 13421 | |
| MAP4K1 (HPK1) | STE20 | STE | 6cqd | A | | phosphoaminophosphonic acid-adenylate ester | Human | 10803 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l24 | B | A | 6-(2-fluoro-6-methoxyphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]-1h-pyrazolo[4,3-c]pyridine | Human | 13422 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l24 | C | A | 6-(2-fluoro-6-methoxyphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]-1h-pyrazolo[4,3-c]pyridine | Human | 13423 | |
| MAP4K1 (HPK1) | STE20 | STE | 6nfy | B | B | n-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 11077 | |
| MAP4K1 (HPK1) | STE20 | STE | 7kac | A | | 5-{[4-{[(1s)-2-hydroxy-1-phenylethyl]amino}-5-(1,3,4-oxadiazol-2-yl)pyrimidin-2-yl]amino}-3,3-dimethyl-2-benzofuran-1(3h)-one | Human | 13231 | |
| MAP4K1 (HPK1) | STE20 | STE | 6cqe | A | B | - | Human | 10804 | |
| MAP4K1 (HPK1) | STE20 | STE | 6nfy | A | A | n-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 11075 | |
| MAP4K1 (HPK1) | STE20 | STE | 7m0k | B | A | 4-anilino-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide | Human | 13476 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l25 | A | B | 6-(2-fluoro-6-methoxyphenyl)-1-[6-(4-methylpiperazin-1-yl)pyridin-2-yl]-1h-pyrazolo[4,3-c]pyridine | Human | 13424 | |
| MAP4K1 (HPK1) | STE20 | STE | 7r9n | A | A | n-{2-(3,3-difluoropyrrolidin-1-yl)-6-[(3r)-pyrrolidin-3-yl]pyrimidin-4-yl}-1-(propan-2-yl)-1h-pyrazolo[4,3-c]pyridin-6-amine | Human | 14025 | |
| MAP4K1 (HPK1) | STE20 | STE | 7m0m | A | B | 4-[2-fluoro-6-(trifluoromethyl)anilino]-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide | Human | 13477 | |
| MAP4K1 (HPK1) | STE20 | STE | 8pau | A | | [(5~{r})-2-[[3,5-bis(fluoranyl)-4-[[3-(trifluoromethyl)-1~{h}-pyrrolo[2,3-b]pyridin-4-yl]oxy]phenyl]amino]-5-fluoranyl-4,6-dihydro-1,3-oxazin-5-yl]methanol | Human | 15317 | |
| MAP4K1 (HPK1) | STE20 | STE | 8cdw | A | A | ~{n}-[4-(1-methylpiperidin-4-yl)phenyl]-7-(1-methylpyrazol-4-yl)quinazolin-2-amine | Human | 14896 | |
| MAP4K1 (HPK1) | STE20 | STE | 6nfz | A | | n-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 11078 | |
| MAP4K1 (HPK1) | STE20 | STE | 6nfy | B | A | n-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 11076 | |
| MAP4K1 (HPK1) | STE20 | STE | 9h8f | A | | 5-cyclopropyl-6-(3-methylimidazo[4,5-c]pyridin-7-yl)-3-[[3-methyl-1-[2,2,2-tris(fluoranyl)ethyl]pyrazol-4-yl]amino]pyrazine-2-carboxamide | Human | 15779 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l25 | B | B | 6-(2-fluoro-6-methoxyphenyl)-1-[6-(4-methylpiperazin-1-yl)pyridin-2-yl]-1h-pyrazolo[4,3-c]pyridine | Human | 13425 | |
| MAP4K1 (HPK1) | STE20 | STE | 8fjz | A | | (3p)-3-{4-[(3r,5s)-3-amino-5-methylpiperidin-1-yl]-6-chloro-7h-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrile | Human | 14691 | |
| MAP4K1 (HPK1) | STE20 | STE | 8pas | A | | 4-[2,6-bis(fluoranyl)-4-(3-morpholin-4-ylpropylcarbamoylamino)phenoxy]-~{n}-[(4-methyl-1,2,5-oxadiazol-3-yl)methyl]-1~{h}-pyrrolo[2,3-b]pyridine-3-carboxamide | Human | 15318 | |
| MAP4K1 (HPK1) | STE20 | STE | 8cij | A | | 2-[[8-azanyl-7-fluoranyl-6-(8-methyl-2,3-dihydro-1~{h}-pyrido[2,3-b][1,4]oxazin-7-yl)isoquinolin-3-yl]amino]-6-propan-2-yl-5,8-dihydro-4~{h}-pyrazolo[1,5-d][1,4]diazepin-7-one | Human | 14897 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l26 | A | A | 6-(2-fluoro-6-methylphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]-1h-indazole-5-carbonitrile | Human | 13427 | |
| MAP4K1 (HPK1) | STE20 | STE | 9wd3 | A | | 5-(8-methoxyimidazo[1,2-a]pyridin-3-yl)-7,7-dimethyl-9-morpholin-4-yl-2,12-dihydrobenzo[b][1,9]phenanthrolin-1-one | Human | 15782 | |
| MAP4K1 (HPK1) | STE20 | STE | 7m0k | A | A | 4-anilino-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide | Human | 13480 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l25 | A | A | 6-(2-fluoro-6-methoxyphenyl)-1-[6-(4-methylpiperazin-1-yl)pyridin-2-yl]-1h-pyrazolo[4,3-c]pyridine | Human | 13428 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l26 | A | B | 6-(2-fluoro-6-methylphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]-1h-indazole-5-carbonitrile | Human | 13429 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l26 | B | A | 6-(2-fluoro-6-methylphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]-1h-indazole-5-carbonitrile | Human | 13430 | |
| MAP4K1 (HPK1) | STE20 | STE | 31wc | A | | 2-cyclopropyl-8-(3-methoxy-1-methyl-pyrazol-4-yl)-3-(3-methylimidazo[4,5-c]pyridin-7-yl)pyrido[3,4-b]pyrazin-5-amine | Human | 15781 | |
| MAP4K1 (HPK1) | STE20 | STE | 7m0k | A | B | 4-anilino-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide | Human | 13481 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l26 | D | A | 6-(2-fluoro-6-methylphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]-1h-indazole-5-carbonitrile | Human | 13431 | |
| MAP4K1 (HPK1) | STE20 | STE | 8par | A | | ~{n}-[3,5-bis(fluoranyl)-4-[[3-[1-(trifluoromethyl)cyclopropyl]-1~{h}-pyrrolo[2,3-b]pyridin-4-yl]oxy]phenyl]-2,9-dioxa-4-azaspiro[5.5]undec-3-en-3-amine | Human | 15319 | |
| MAP4K1 (HPK1) | STE20 | STE | 7l26 | D | B | 6-(2-fluoro-6-methylphenyl)-1-[4-(4-methylpiperazin-1-yl)phenyl]-1h-indazole-5-carbonitrile | Human | 13432 | |
| MAP4K1 (HPK1) | STE20 | STE | 6nfy | A | B | n-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 11072 | |
| STK25 (YSK1) | STE20 | STE | 4nzw | B | | 5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 464 | |
| STK25 (YSK1) | STE20 | STE | 2xik | A | B | 5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 465 | |
| STK25 (YSK1) | STE20 | STE | 7z4v | A | A | ~{n}-(5-~{tert}-butyl-1~{h}-pyrazol-3-yl)-4-pyrrolidin-1-ylsulfonyl-benzamide | Human | 14176 | |
| STK25 (YSK1) | STE20 | STE | 2xik | A | A | 5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 463 | |
| STK25 (YSK1) | STE20 | STE | 7z4v | A | B | ~{n}-(5-~{tert}-butyl-1~{h}-pyrazol-3-yl)-4-pyrrolidin-1-ylsulfonyl-benzamide | Human | 14177 | |
| STRADA (STLK5) | STE20 | STE | 3gni | B | | adenosine-5'-triphosphate | Human | 3486 | |
| STRADA (STLK5) | STE20 | STE | 8vsu | C | | - | Human | 15320 | |
| PAK2 | STE20 | STE | 9ws3 | A | B | - | Human | 15816 | |
| PAK2 | STE20 | STE | 9ws6 | A | | phosphoaminophosphonic acid-adenylate ester | Human | 15818 | |
| PAK2 | STE20 | STE | 9lbf | A | | - | Human | 15814 | |
| PAK2 | STE20 | STE | 9d51 | A | | n~2~-{[(1s,4s)-4-aminocyclohexyl]methyl}-n~4~-[5-(trifluoromethyl)-1,3-thiazol-2-yl]pyrimidine-2,4-diamine | Human | 15815 | |
| TNIK | STE20 | STE | 5cwz | A | | - | Human | 6891 | |
| TNIK | STE20 | STE | 6ra5 | B | | - | Human | 12237 | |
| TNIK | STE20 | STE | 5d7a | A | | cis-4-{[2-(1h-benzimidazol-5-ylamino)quinazolin-8-yl]oxy}cyclohexanol | Human | 6963 | |
| TNIK | STE20 | STE | 2x7f | B | B | 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2h,6h)-dione | Human | 1947 | |
| TNIK | STE20 | STE | 2x7f | B | A | 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2h,6h)-dione | Human | 1950 | |
| TNIK | STE20 | STE | 2x7f | A | A | 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2h,6h)-dione | Human | 1943 | |
| TNIK | STE20 | STE | 2x7f | A | B | 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2h,6h)-dione | Human | 1951 | |
| TNIK | STE20 | STE | 5cwz | C | | - | Human | 6888 | |
| TNIK | STE20 | STE | 8wm0 | A | B | adenosine | Human | 15231 | |
| TNIK | STE20 | STE | 2x7f | C | A | 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2h,6h)-dione | Human | 1942 | |
| TNIK | STE20 | STE | 5ax9 | A | | 4-methoxy-3-[2-[(3-methoxy-4-morpholin-4-yl-phenyl)amino]pyridin-4-yl]benzenecarbonitrile | Human | 6887 | |
| TNIK | STE20 | STE | 5d7a | C | | cis-4-{[2-(1h-benzimidazol-5-ylamino)quinazolin-8-yl]oxy}cyclohexanol | Human | 6965 | |
| TNIK | STE20 | STE | 7xzq | A | | - | Human | 14474 | |
| TNIK | STE20 | STE | 6ra7 | A | A | 2-[8-azanyl-2-(2-fluoranylpyridin-4-yl)-1,7-naphthyridin-5-yl]propan-2-ol | Human | 11801 | |
| TNIK | STE20 | STE | 7xzr | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 14475 | |
| TNIK | STE20 | STE | 8x88 | A | | - | Human | 15060 | |
| TNIK | STE20 | STE | 2x7f | E | A | 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2h,6h)-dione | Human | 1946 | |
| TNIK | STE20 | STE | 5ax9 | C | | 4-methoxy-3-[2-[(3-methoxy-4-morpholin-4-yl-phenyl)amino]pyridin-4-yl]benzenecarbonitrile | Human | 6889 | |
| TNIK | STE20 | STE | 6ra5 | A | | 5-bromanyl-2-(2-fluoranylpyridin-4-yl)-1,7-naphthyridin-8-amine | Human | 12238 | |
| PAK4 | STE20 | STE | 4jdj | A | B | - | Human | 1397 | |
| PAK4 | STE20 | STE | 2q0n | A | B | - | Human | 1401 | |
| PAK4 | STE20 | STE | 8ahg | A | B | ~{n}-methyl-3-propan-2-yl-1~{h}-pyrazolo[3,4-c]pyridine-4-carboxamide | Human | 14368 | |
| PAK4 | STE20 | STE | 5i0b | A | | 6-bromo-2-[1-methyl-3-(propan-2-yl)-1h-pyrazol-4-yl]-1h-imidazo[4,5-b]pyridine | Human | 7315 | |
| PAK4 | STE20 | STE | 8ahi | A | | ~{n}-methyl-1,3-benzothiazole-6-carboxamide | Human | 14369 | |
| PAK4 | STE20 | STE | 4jdi | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 1380 | |
| PAK4 | STE20 | STE | 4fii | A | B | - | Human | 1396 | |
| PAK4 | STE20 | STE | 6wly | A | B | - | Human | 12396 | |
| PAK4 | STE20 | STE | 4app | A | A | n-[6,6-dimethyl-5-[(2s)-4-methyl-2-(phenylmethyl)piperazin-1-yl]carbonyl-2,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-phenoxy-benzamide | Human | 1385 | |
| PAK4 | STE20 | STE | 4fii | A | A | - | Human | 1383 | |
| PAK4 | STE20 | STE | 6wly | A | A | - | Human | 12397 | |
| PAK4 | STE20 | STE | 4l67 | A | | - | Human | 1376 | |
| PAK4 | STE20 | STE | 5vee | A | | 6-(2,4-dichlorophenyl)-8-ethyl-2-{[3-fluoro-4-(piperazin-1-yl)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 8572 | |
| PAK4 | STE20 | STE | 8ahg | A | A | ~{n}-methyl-3-propan-2-yl-1~{h}-pyrazolo[3,4-c]pyridine-4-carboxamide | Human | 14370 | |
| PAK4 | STE20 | STE | 5vef | A | B | 5-(1,4-diazepan-1-sulfonyl)isoquinoline | Human | 8571 | |
| PAK4 | STE20 | STE | 4jdh | A | B | - | Human | 1406 | |
| PAK4 | STE20 | STE | 2bva | A | | - | Human | 1394 | |
| PAK4 | STE20 | STE | 5upl | A | | - | Human | 9436 | |
| PAK4 | STE20 | STE | 5xvf | A | | 2-(4-azanylpiperidin-1-yl)-6-chloranyl-n-(1-methylimidazol-4-yl)quinazolin-4-amine | Human | 9549 | |
| PAK4 | STE20 | STE | 4fig | B | | phosphoaminophosphonic acid-adenylate ester | Human | 1373 | |
| PAK4 | STE20 | STE | 5zjw | A | B | (3z)-n-[(1s)-2-hydroxy-1-phenylethyl]-3-[(1h-imidazol-2-yl)(phenyl)methylidene]-2-oxo-2,3-dihydro-1h-indole-5-carboxamide | Human | 11000 | |
| PAK4 | STE20 | STE | 6wly | A | C | - | Human | 12398 | |
| PAK4 | STE20 | STE | 2j0i | A | B | - | Human | 1377 | |
| PAK4 | STE20 | STE | 4fih | A | A | - | Human | 1399 | |
| PAK4 | STE20 | STE | 5xvg | A | | [6-chloranyl-4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl]-[(3r)-3-methylpiperazin-1-yl]methanone | Human | 9551 | |
| PAK4 | STE20 | STE | 2x4z | A | | pf-3758309 | Human | 1387 | |
| PAK4 | STE20 | STE | 4xbr | A | | adenosine-5'-triphosphate | Human | 6257 | |
| PAK4 | STE20 | STE | 6wlx | A | A | - | Human | 12399 | |
| PAK4 | STE20 | STE | 5vef | A | A | 5-(1,4-diazepan-1-sulfonyl)isoquinoline | Human | 8569 | |
| PAK4 | STE20 | STE | 7cp4 | A | | [1-(2-azanylpyrimidin-4-yl)-6-[2-(1-oxidanylcyclohexyl)ethynyl]indol-3-yl]-[(3s)-3-methylpiperazin-1-yl]methanone | Human | 13850 | |
| PAK4 | STE20 | STE | 5ved | A | | staurosporine | Human | 8570 | |
| PAK4 | STE20 | STE | 8ahh | A | B | 5-cyano-~{n}-methyl-pyrazolo[1,5-a]pyridine-3-carboxamide | Human | 14371 | |
| PAK4 | STE20 | STE | 4njd | A | B | n-(1h-indazol-5-yl)-n'-[2-(1h-indol-3-yl)ethyl]-6-methoxy-1,3,5-triazine-2,4-diamine | Human | 1384 | |
| PAK4 | STE20 | STE | 4jdi | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 1403 | |
| PAK4 | STE20 | STE | 4fif | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 1395 | |
| PAK4 | STE20 | STE | 7s47 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 14494 | |
| PAK4 | STE20 | STE | 4fih | A | B | - | Human | 1402 | |
| PAK4 | STE20 | STE | 7s46 | A | | phosphoaminophosphonic acid-adenylate ester | Human | 14495 | |
| PAK4 | STE20 | STE | 8ahh | A | A | 5-cyano-~{n}-methyl-pyrazolo[1,5-a]pyridine-3-carboxamide | Human | 14372 | |
| PAK4 | STE20 | STE | 2j0i | A | A | - | Human | 1391 | |
| PAK4 | STE20 | STE | 4fif | B | A | phosphoaminophosphonic acid-adenylate ester | Human | 1381 | |
| STK10 (LOK) | STE20 | STE | 6eim | B | A | ~{n}-[5-[4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-1~{h}-benzimidazol-2-yl]furan-2-carboxamide | Human | 8623 | |
| STK10 (LOK) | STE20 | STE | 4equ | A | A | n-{3-[(3-{4-[(4-methoxyphenyl)amino]-1,3,5-triazin-2-yl}pyridin-2-yl)amino]-4-methylphenyl}-3-(trifluoromethyl)benzamide | Human | 957 | |
| STK10 (LOK) | STE20 | STE | 5owq | A | B | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | 8386 | |
| STK10 (LOK) | STE20 | STE | 6hxf | C | B | 3-(2-methoxyphenyl)-4-[[4-(phenylcarbonyl)phenyl]amino]pyrrole-2,5-dione | Human | 10655 | |
| STK10 (LOK) | STE20 | STE | 4aot | A | A | 1-(4-{methyl[2-({4-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]amino}phenyl)-3-{3-[(4-methylpiperazin-1-yl)carbonyl]phenyl}urea | Human | 947 | |
| STK10 (LOK) | STE20 | STE | 7qgp | A | | 1-[(4-chloranyl-2-methyl-phenyl)methyl]-3-(7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.1^{2,6}.0^{17,20}]docosa-1(20),2(22),3,5,14(21),15,18-heptaen-5-yl)urea | Human | 14075 | |
| STK10 (LOK) | STE20 | STE | 4usd | A | A | 4-{5-(6-methoxynaphthalen-2-yl)-1-methyl-2-[2-methyl-4-(methylsulfonyl)phenyl]-1h-imidazol-4-yl}pyridine | Human | 953 | |
| STK10 (LOK) | STE20 | STE | 5owr | A | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 8388 | |
| STK10 (LOK) | STE20 | STE | 4usd | B | A | 4-{5-(6-methoxynaphthalen-2-yl)-1-methyl-2-[2-methyl-4-(methylsulfonyl)phenyl]-1h-imidazol-4-yl}pyridine | Human | 939 | |
| STK10 (LOK) | STE20 | STE | 5ajq | A | A | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 950 | |
| STK10 (LOK) | STE20 | STE | 6i2y | A | | n-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 10787 | |
| STK10 (LOK) | STE20 | STE | 4use | A | B | 4-{5-(6-methoxynaphthalen-2-yl)-1-methyl-2-[2-methyl-4-(methylsulfonyl)phenyl]-1h-imidazol-4-yl}pyridine | Human | 951 | |
| STK10 (LOK) | STE20 | STE | 4aot | A | B | 1-(4-{methyl[2-({4-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]amino}phenyl)-3-{3-[(4-methylpiperazin-1-yl)carbonyl]phenyl}urea | Human | 944 | |
| STK10 (LOK) | STE20 | STE | 4equ | A | B | n-{3-[(3-{4-[(4-methoxyphenyl)amino]-1,3,5-triazin-2-yl}pyridin-2-yl)amino]-4-methylphenyl}-3-(trifluoromethyl)benzamide | Human | 938 | |
| STK10 (LOK) | STE20 | STE | 5owq | A | A | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | 8385 | |
| STK4 (MST1) | STE20 | STE | 3com | B | | - | Human | 2829 | |
| STK4 (MST1) | STE20 | STE | 3com | A | | - | Human | 2828 | |
| STK4 (MST1) | STE20 | STE | 6yat | A | | 4-[5-(3-chlorophenyl)-7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl]morpholine | Human | 12241 | |
| STK4 (MST1) | STE20 | STE | 6yat | B | | 4-[5-(3-chlorophenyl)-7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl]morpholine | Human | 12242 | |
| STK3 (MST2) | STE20 | STE | 5dh3 | A | A | 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5h-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide | Human | 7031 | |
| STK3 (MST2) | STE20 | STE | 8a66 | A | A | 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5h-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide | Human | 14323 | |
| STK3 (MST2) | STE20 | STE | 5dh3 | B | A | 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5h-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide | Human | 7029 | |
| STK3 (MST2) | STE20 | STE | 4lg4 | F | A | - | Human | 1431 | |
| STK3 (MST2) | STE20 | STE | 4lg4 | D | A | - | Human | 1435 | |
| STK3 (MST2) | STE20 | STE | 4lg4 | D | B | - | Human | 1434 | |
| STK3 (MST2) | STE20 | STE | 6ao5 | A | | phosphoaminophosphonic acid-adenylate ester | Human | 8662 | |
| STK3 (MST2) | STE20 | STE | 4lg4 | E | B | - | Human | 1441 | |
| STK3 (MST2) | STE20 | STE | 4lgd | D | | phosphoaminophosphonic acid-adenylate ester | Human | 1430 | |
| STK3 (MST2) | STE20 | STE | 4lg4 | F | B | - | Human | 1436 | |
| STK3 (MST2) | STE20 | STE | 5dh3 | A | B | 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5h-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide | Human | 7028 | |
| STK3 (MST2) | STE20 | STE | 4lg4 | E | A | - | Human | 1439 | |
| MAP4K4 (HGK) | STE20 | STE | 5w5q | A | B | (5s,7s)-n~3~-methyl-10-[3-methyl-3-(5-methyl-1,3-oxazol-2-yl)but-1-yn-1-yl]-6,7-dihydro-5h-5,7-methanoimidazo[2,1-a][2]benzazepine-2,3-dicarboxamide | Human | 10005 | |
| MAP4K4 (HGK) | STE20 | STE | 4u40 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 6332 | |
| MAP4K4 (HGK) | STE20 | STE | 4u44 | B | B | - | Human | 2740 | |
| MAP4K4 (HGK) | STE20 | STE | 4u44 | A | B | 6-phenyl-n-(pyridin-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine | Human | 2745 | |
| MAP4K4 (HGK) | STE20 | STE | 4u41 | B | A | - | Human | 6341 | |
| MAP4K4 (HGK) | STE20 | STE | 4obq | B | B | - | Human | 2742 | |
| MAP4K4 (HGK) | STE20 | STE | 4u41 | B | B | - | Human | 6328 | |
| MAP4K4 (HGK) | STE20 | STE | 4obp | A | B | 6-(2-fluoropyridin-4-yl)pyrido[3,2-d]pyrimidin-4-amine | Human | 2761 | |
| MAP4K4 (HGK) | STE20 | STE | 4obp | B | B | - | Human | 2757 | |
| MAP4K4 (HGK) | STE20 | STE | 4zp5 | A | | 4-[5-(4-chlorophenyl)-1,3-oxazol-2-yl]benzamide | Human | 7091 | |
| MAP4K4 (HGK) | STE20 | STE | 4u42 | A | A | 6-[(3s)-3-(4-methyl-1h-pyrazol-3-yl)piperidin-1-yl]pyrido[3,2-d]pyrimidin-4-amine | Human | 6335 | |
| MAP4K4 (HGK) | STE20 | STE | 4u43 | B | B | - | Human | 2743 | |
| MAP4K4 (HGK) | STE20 | STE | 5w5q | A | A | (5s,7s)-n~3~-methyl-10-[3-methyl-3-(5-methyl-1,3-oxazol-2-yl)but-1-yn-1-yl]-6,7-dihydro-5h-5,7-methanoimidazo[2,1-a][2]benzazepine-2,3-dicarboxamide | Human | 10008 | |
| MAP4K4 (HGK) | STE20 | STE | 4u3y | A | B | - | Human | 6340 | |
| MAP4K4 (HGK) | STE20 | STE | 4obo | A | A | 6-(3-chlorophenyl)quinazolin-4-amine | Human | 2746 | |
| MAP4K4 (HGK) | STE20 | STE | 4u45 | A | A | 6-(1h-pyrazol-4-yl)-n-(pyridin-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine | Human | 2747 | |
| MAP4K4 (HGK) | STE20 | STE | 5di1 | B | | - | Human | 6353 | |
| MAP4K4 (HGK) | STE20 | STE | 4u43 | B | A | - | Human | 2753 | |
| MAP4K4 (HGK) | STE20 | STE | 4u43 | A | B | n-(pyridin-3-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine | Human | 2738 | |
| MAP4K4 (HGK) | STE20 | STE | 4rvt | B | B | - | Human | 2739 | |
| MAP4K4 (HGK) | STE20 | STE | 5j95 | A | | 1-{4-[6-amino-5-(4-chlorophenyl)pyridin-3-yl]phenyl}cyclopentane-1-carboxylic acid | Human | 7999 | |
| MAP4K4 (HGK) | STE20 | STE | 4rvt | B | A | - | Human | 2749 | |
| MAP4K4 (HGK) | STE20 | STE | 4rvt | A | A | 3-hexanoyl-4-hydroxy-5-(4-hydroxyphenyl)pyridin-2(1h)-one | Human | 2751 | |
| MAP4K4 (HGK) | STE20 | STE | 4u40 | B | A | - | Human | 6342 | |
| MAP4K4 (HGK) | STE20 | STE | 4u3y | B | A | - | Human | 6344 | |
| MAP4K4 (HGK) | STE20 | STE | 4obp | B | A | - | Human | 2754 | |
| MAP4K4 (HGK) | STE20 | STE | 4u3z | A | B | - | Human | 6326 | |
| MAP4K4 (HGK) | STE20 | STE | 4zk5 | B | | - | Human | 6014 | |
| MAP4K4 (HGK) | STE20 | STE | 5w5q | B | B | - | Human | 10006 | |
| MAP4K4 (HGK) | STE20 | STE | 4u45 | A | B | 6-(1h-pyrazol-4-yl)-n-(pyridin-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine | Human | 2759 | |
| MAP4K4 (HGK) | STE20 | STE | 4obo | A | B | 6-(3-chlorophenyl)quinazolin-4-amine | Human | 2744 | |
| MAP4K4 (HGK) | STE20 | STE | 4u42 | B | A | 6-[(3s)-3-(4-methyl-1h-pyrazol-3-yl)piperidin-1-yl]pyrido[3,2-d]pyrimidin-4-amine | Human | 6330 | |
| MAP4K4 (HGK) | STE20 | STE | 4u41 | A | A | 6-[(3s)-3-(4-methyl-1h-pyrazol-3-yl)piperidin-1-yl]pyrido[3,2-d]pyrimidin-4-amine | Human | 6338 | |
| MAP4K4 (HGK) | STE20 | STE | 4u41 | A | B | 6-[(3s)-3-(4-methyl-1h-pyrazol-3-yl)piperidin-1-yl]pyrido[3,2-d]pyrimidin-4-amine | Human | 6334 | |
| MAP4K4 (HGK) | STE20 | STE | 4obq | A | A | n-[3-(4-aminoquinazolin-6-yl)-5-fluorophenyl]-2-(pyrrolidin-1-yl)acetamide | Human | 2758 | |
| MAP4K4 (HGK) | STE20 | STE | 4obo | B | A | - | Human | 2762 | |
| MAP4K4 (HGK) | STE20 | STE | 4obq | A | B | n-[3-(4-aminoquinazolin-6-yl)-5-fluorophenyl]-2-(pyrrolidin-1-yl)acetamide | Human | 2755 | |
| PAK4 | STE20 | STE | 9wdf | A | | (~{e})-3-(6-azanylpyridin-3-yl)-~{n}-[[(2~{s})-7-chloranyl-5-(4-piperazin-1-ylcarbonylphenyl)-2,3-dihydro-1-benzofuran-2-yl]methyl]prop-2-enamide | Human | 16117 | |
| PAK2 | STE20 | STE | 9m41 | A | | - | Human | 15817 | |
| PAK4 | STE20 | STE | 9d53 | A | | n~2~-{[(1s,4s)-4-aminocyclohexyl]methyl}-n~4~-(5-cyclopropyl-1,3-thiazol-2-yl)pyrimidine-2,4-diamine | Human | 16118 | |
