| KDR | VEGFR | TK | 3c7q | A | | methyl (3z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1h-indole-6-carboxylate | Human | 5334 | |
| KDR | VEGFR | TK | 1y6a | A | A | n-[5-(ethylsulfonyl)-2-methoxyphenyl]-5-[3-(2-pyridinyl)phenyl]-1,3-oxazol-2-amine | Human | 5339 | |
| KDR | VEGFR | TK | 3wze | A | B | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 5320 | |
| KDR | VEGFR | TK | 3wze | A | A | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 5336 | |
| KDR | VEGFR | TK | 3vid | A | | 4,5,6,11-tetrahydro-1h-pyrazolo[4',3':6,7]cyclohepta[1,2-b]indole | Human | 5335 | |
| KDR | VEGFR | TK | 3vnt | A | A | 2-chloro-3-(1-cyanocyclopropyl)-n-[5-({2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}oxy)-2-fluorophenyl]benzamide | Human | 5312 | |
| KDR | VEGFR | TK | 3wzd | A | B | 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide | Human | 5350 | |
| KDR | VEGFR | TK | 3cjf | A | B | n~4~-(3-methyl-1h-indazol-6-yl)-n~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine | Human | 6794 | |
| KDR | VEGFR | TK | 5ew3 | A | | 2-(pyridin-4-ylmethylamino)-~{n}-[3-(trifluoromethyl)phenyl]benzamide | Human | 6289 | |
| KDR | VEGFR | TK | 1y6b | A | | n-(cyclopropylmethyl)-4-(methyloxy)-3-({5-[3-(3-pyridinyl)phenyl]-1,3-oxazol-2-yl}amino)benzenesulfonamide | Human | 5345 | |
| KDR | VEGFR | TK | 6gqo | A | B | 2-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxy-phenyl]-~{n}-(1-propan-2-ylpyrazol-4-yl)ethanamide | Human | 10583 | |
| KDR | VEGFR | TK | 2p2i | A | | n-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide | Human | 5326 | |
| KDR | VEGFR | TK | 3efl | B | | n-(3,3-dimethyl-2,3-dihydro-1h-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide | Human | 5330 | |
| KDR | VEGFR | TK | 5ew3 | B | | 2-(pyridin-4-ylmethylamino)-~{n}-[3-(trifluoromethyl)phenyl]benzamide | Human | 6290 | |
| KDR | VEGFR | TK | 3cjg | A | A | n~4~-methyl-n~4~-(3-methyl-1h-indazol-6-yl)-n~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine | Human | 6791 | |
| KDR | VEGFR | TK | 3vhe | A | | 1-{2-fluoro-4-[(5-methyl-5h-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-[3-(trifluoromethyl)phenyl]urea | Human | 5331 | |
| KDR | VEGFR | TK | 4agd | A | | n-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 5322 | |
| KDR | VEGFR | TK | 3vhk | A | | {3-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methoxy]phenyl}methanol | Human | 5342 | |
| KDR | VEGFR | TK | 3b8r | B | | n-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide | Human | 5341 | |
| KDR | VEGFR | TK | 3b8r | A | | n-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide | Human | 5327 | |
| KDR | VEGFR | TK | 3ewh | A | | n-[4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)naphthalen-1-yl]-6-(trifluoromethyl)-1h-benzimidazol-2-amine | Human | 5351 | |
| KDR | VEGFR | TK | 3cjf | A | A | n~4~-(3-methyl-1h-indazol-6-yl)-n~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine | Human | 6792 | |
| KDR | VEGFR | TK | 3dtw | B | | 6-chloro-n-pyrimidin-5-yl-3-{[3-(trifluoromethyl)phenyl]amino}-1,2-benzisoxazole-7-carboxamide | Human | 5308 | |
| KDR | VEGFR | TK | 3be2 | A | | n-{3-[3-(dimethylamino)propyl]-5-(trifluoromethyl)phenyl}-4-methyl-3-[(3-pyrimidin-4-ylpyridin-2-yl)amino]benzamide | Human | 5337 | |
| KDR | VEGFR | TK | 6gqq | A | B | ~{n}-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-2-(4-propan-2-yl-1,2,3-triazol-1-yl)ethanamide | Human | 10585 | |
| KDR | VEGFR | TK | 3cp9 | B | | 3-(2-aminoquinazolin-6-yl)-1-(3,3-dimethylindolin-6-yl)-4-methylpyridin-2(1h)-one | Human | 6790 | |
| KDR | VEGFR | TK | 3wzd | A | A | 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide | Human | 5325 | |
| KDR | VEGFR | TK | 3vnt | A | B | 2-chloro-3-(1-cyanocyclopropyl)-n-[5-({2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}oxy)-2-fluorophenyl]benzamide | Human | 5328 | |
| KDR | VEGFR | TK | 3efl | A | | n-(3,3-dimethyl-2,3-dihydro-1h-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide | Human | 5344 | |
| KDR | VEGFR | TK | 6gqq | A | A | ~{n}-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-2-(4-propan-2-yl-1,2,3-triazol-1-yl)ethanamide | Human | 10581 | |
| KDR | VEGFR | TK | 4asd | A | | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 5333 | |
| KDR | VEGFR | TK | 2qu6 | A | | 4-({2-[(4-chloro-3-{[(2s)-1-methylpyrrolidin-2-yl]methoxy}phenyl)amino]-1,3-benzoxazol-5-yl}oxy)-n-methylpyridine-2-carboxamide | Human | 5316 | |
| KDR | VEGFR | TK | 3vo3 | A | A | n-[3-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)phenyl]-1,3-dimethyl-1h-pyrazole-5-carboxamide | Human | 5329 | |
| KDR | VEGFR | TK | 4ase | A | | tivozanib | Human | 5349 | |
| KDR | VEGFR | TK | 2oh4 | A | B | methyl (5-{4-[({[2-fluoro-5-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-1h-benzimidazol-2-yl)carbamate | Human | 5324 | |
| KDR | VEGFR | TK | 2p2h | A | | 4-(2-anilinopyridin-3-yl)-n-(3,4,5-trimethoxyphenyl)-1,3,5-triazin-2-amine | Human | 5310 | |
| KDR | VEGFR | TK | 2qu6 | B | | 4-({2-[(4-chloro-3-{[(2s)-1-methylpyrrolidin-2-yl]methoxy}phenyl)amino]-1,3-benzoxazol-5-yl}oxy)-n-methylpyridine-2-carboxamide | Human | 5340 | |
| KDR | VEGFR | TK | 3cpc | B | | 3-(2-aminoquinazolin-6-yl)-4-methyl-1-[3-(trifluoromethyl)phenyl]pyridin-2(1h)-one | Human | 5309 | |
| KDR | VEGFR | TK | 2xir | A | | n,2-dimethyl-6-{[7-(2-morpholin-4-ylethoxy)quinolin-4-yl]oxy}-1-benzofuran-3-carboxamide | Human | 6789 | |
| KDR | VEGFR | TK | 6gqp | A | A | ~{n}-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-2-(1-ethylpyrazol-4-yl)ethanamide | Human | 10582 | |
| KDR | VEGFR | TK | 3cpc | A | | 3-(2-aminoquinazolin-6-yl)-4-methyl-1-[3-(trifluoromethyl)phenyl]pyridin-2(1h)-one | Human | 5346 | |
| KDR | VEGFR | TK | 1vr2 | A | | - | Human | 5338 | |
| KDR | VEGFR | TK | 4ag8 | A | | axitinib | Human | 5311 | |
| KDR | VEGFR | TK | 3cp9 | A | | 3-(2-aminoquinazolin-6-yl)-1-(3,3-dimethylindolin-6-yl)-4-methylpyridin-2(1h)-one | Human | 6786 | |
| KDR | VEGFR | TK | 2qu5 | A | | 4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3h-benzimidazol-5-yl]oxy]-n-methyl-pyridine-2-carboxamide | Human | 5317 | |
| KDR | VEGFR | TK | 1y6a | A | B | n-[5-(ethylsulfonyl)-2-methoxyphenyl]-5-[3-(2-pyridinyl)phenyl]-1,3-oxazol-2-amine | Human | 5323 | |
| KDR | VEGFR | TK | 4agc | A | | axitinib | Human | 5343 | |
| FLT1 | VEGFR | TK | 3hng | A | B | n-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide | Human | 3838 | |
| FLT1 | VEGFR | TK | 3hng | A | A | n-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide | Human | 3837 | |
| KDR | VEGFR | TK | 3b8q | A | | n-(4-chlorophenyl)-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide | Human | 5332 | |
| KDR | VEGFR | TK | 6xvk | A | | ~{n}-(4,4-dimethyl-2-prop-1-ynyl-3,1-benzoxazin-6-yl)-2-[3-methoxy-5-(7-methoxyquinolin-4-yl)oxy-pyridin-2-yl]ethanamide | Human | 12273 | |
| KDR | VEGFR | TK | 3b8q | B | | n-(4-chlorophenyl)-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide | Human | 5319 | |
| KDR | VEGFR | TK | 2rl5 | A | | n-(4-chlorophenyl)-7-[(6,7-dimethoxyquinolin-4-yl)oxy]-2,3-dihydro-1,4-benzoxazine-4-carboxamide | Human | 5348 | |
| KDR | VEGFR | TK | 3vo3 | A | B | n-[3-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)phenyl]-1,3-dimethyl-1h-pyrazole-5-carboxamide | Human | 5321 | |
| KDR | VEGFR | TK | 3cpb | B | | n'-(6-aminopyridin-3-yl)-n-(2-cyclopentylethyl)-4-methyl-benzene-1,3-dicarboxamide | Human | 6793 | |
| KDR | VEGFR | TK | 3u6j | A | | n-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazole-4-carboxamide | Human | 5318 | |
| KDR | VEGFR | TK | 3cpb | A | | n'-(6-aminopyridin-3-yl)-n-(2-cyclopentylethyl)-4-methyl-benzene-1,3-dicarboxamide | Human | 6787 | |
| KDR | VEGFR | TK | 6gqp | A | B | ~{n}-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-2-(1-ethylpyrazol-4-yl)ethanamide | Human | 10584 | |
| KDR | VEGFR | TK | 3dtw | A | | 6-chloro-n-pyrimidin-5-yl-3-{[3-(trifluoromethyl)phenyl]amino}-1,2-benzisoxazole-7-carboxamide | Human | 5313 | |
| KDR | VEGFR | TK | 2oh4 | A | A | methyl (5-{4-[({[2-fluoro-5-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-1h-benzimidazol-2-yl)carbamate | Human | 5347 | |
| KDR | VEGFR | TK | 3cjg | A | B | n~4~-methyl-n~4~-(3-methyl-1h-indazol-6-yl)-n~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine | Human | 6788 | |
| KDR | VEGFR | TK | 2p2i | B | | n-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide | Human | 5315 | |
| KDR | VEGFR | TK | 1ywn | A | | n-{4-[4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-5-yl]phenyl}-n'-[2-fluoro-5-(trifluoromethyl)phenyl]urea | Human | 5314 | |
| KDR | VEGFR | TK | 6gqo | A | A | 2-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxy-phenyl]-~{n}-(1-propan-2-ylpyrazol-4-yl)ethanamide | Human | 10580 | |
| KDR | VEGFR | TK | 6xvj | A | | ~{n}-[3-[(dimethylamino)methyl]-5-methyl-phenyl]-2-[3-methoxy-5-(7-methoxyquinolin-4-yl)oxy-pyridin-2-yl]ethanamide | Human | 12274 | |
