| TTK | TTK | Other | 5nad | A | | bay 1217389 | Human | 7975 | |
| TTK | TTK | Other | 6tnd | A | B | bay 1217389 | Human | 12272 | |
| AURKA (AurA) | Aur | Other | 8c1h | A | A | adenosine-5'-diphosphate | Human | 15147 | |
| TTK | TTK | Other | 3h9f | A | B | 9-cyclopentyl-2-(4-(4-hydroxypiperidin-1-yl)-2-methoxyphenylamino)-5-methyl-8,9-dihydro-5h-pyrimido[4,5-b][1,4]diazepin-6(7h)-one | Human | 4712 | |
| PLK1 | PLK | Other | 4j52 | A | B | 4-{[(7r)-9-cyclopentyl-7-ethenyl-7-fluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5h-pyrimido[4,5-b][1,4]diazepin-2-yl]amino}-3-methoxy-n-(4-methylpiperazin-1-yl)benzamide | Human | 4976 | |
| AURKA (AurA) | Aur | Other | 4uzd | A | | ethyl (9s)-9-[3-(1h-benzimidazol-2-yloxy)phenyl]-8-oxo-4,5,6,7,8,9-hexahydro-2h-pyrrolo[3,4-b]quinoline-3-carboxylate | Human | 2013 | |
| AURKA (AurA) | Aur | Other | 2wtv | A | A | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 2056 | |
| TP53RK (PRPK) | Bud32 | Other | 7szd | A | | 2-[(3r)-3-methyl-2,6-dioxopiperidin-3-yl]-1,3-dioxo-2,3-dihydro-1h-isoindole-5-carboxylic acid | Human | 14558 | |
| TP53RK (PRPK) | Bud32 | Other | 7szc | A | | 4-hydroxy-2-[(3r)-3-methyl-2,6-dioxopiperidin-3-yl]-1h-isoindole-1,3(2h)-dione | Human | 14559 | |
| IKBKB (IKKb) | IKK | Other | 4e3c | E | | - | Human | 289 | |
| AURKA (AurA) | Aur | Other | 6c2t | A | B | (2s,4r)-1-[(3-chloro-2-fluorophenyl)methyl]-2-methyl-4-({3-[(1,3-thiazol-2-yl)amino]isoquinolin-1-yl}methyl)piperidine-4-carboxylic acid | Human | 10863 | |
| PLK2 | PLK | Other | 4i5p | A | A | (7r)-8-cyclopentyl-7-ethyl-5-methyl-2-(1h-pyrrol-2-yl)-7,8-dihydropteridin-6(5h)-one | Human | 5559 | |
| PLK2 | PLK | Other | 4i6h | A | A | (7r)-8-cyclopentyl-7-ethyl-5-methyl-2-[2-(1,3-thiazol-4-yl)-1h-imidazol-1-yl]-7,8-dihydropteridin-6(5h)-one | Human | 5558 | |
| PLK2 | PLK | Other | 4i6f | A | A | (7r)-8-cyclopentyl-7-ethyl-5-methyl-2-(2-phenyl-1h-imidazol-1-yl)-7,8-dihydropteridin-6(5h)-one | Human | 5564 | |
| PLK2 | PLK | Other | 4i5p | A | B | (7r)-8-cyclopentyl-7-ethyl-5-methyl-2-(1h-pyrrol-2-yl)-7,8-dihydropteridin-6(5h)-one | Human | 5560 | |
| EIF2AK2 (PKR) | PEK | Other | 6d3l | A | | - | Human | 11384 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6cmj | B | A | 2-(2-methylpropyl)-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9786 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5vt1 | A | | 4-({5-[(3-hydroxy-4-methylphenyl)amino]-4-oxo-4h-1,2,6-thiadiazin-3-yl}amino)benzamide | Human | 7591 | |
| TBK1 | IKK | Other | 4im0 | A | B | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 607 | |
| TBK1 | IKK | Other | 4euu | A | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 615 | |
| STK16 (MPSK1) | NAK | Other | 2buj | B | | staurosporine | Human | 2230 | |
| TBK1 | IKK | Other | 4eut | A | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 621 | |
| TBK1 | IKK | Other | 6cq5 | A | | 2-amino-7-(1,1-dioxo-1lambda~6~-thian-4-yl)-5-oxo-5h-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid | Human | 10758 | |
| TBK1 | IKK | Other | 4iwq | A | | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 605 | |
| AURKA (AurA) | Aur | Other | 3w2c | E | | 2-{4-[3-(1h-benzimidazol-2-yl)-1h-indazol-6-yl]-1h-pyrazol-1-yl}-n-(3-methylbutyl)acetamide | Human | 1953 | |
| AURKA (AurA) | Aur | Other | 3w10 | A | | 1-(3-methoxyphenyl)-n-(5-methyl-1h-pyrazol-3-yl)isoquinolin-3-amine | Human | 2068 | |
| AURKA (AurA) | Aur | Other | 4uyn | A | | ethyl (9s)-9-[5-(1h-benzimidazol-2-ylsulfanyl)furan-2-yl]-8-hydroxy-5,6,7,9-tetrahydro-2h-pyrrolo[3,4-b]quinoline-3-carboxylate | Human | 2002 | |
| AURKA (AurA) | Aur | Other | 2dwb | A | | phosphoaminophosphonic acid-adenylate ester | Human | 2035 | |
| AURKA (AurA) | Aur | Other | 5os5 | A | B | adenosine-5'-diphosphate | Human | 8629 | |
| AURKA (AurA) | Aur | Other | 3w2c | C | | 2-{4-[3-(1h-benzimidazol-2-yl)-1h-indazol-6-yl]-1h-pyrazol-1-yl}-n-(3-methylbutyl)acetamide | Human | 2021 | |
| AURKA (AurA) | Aur | Other | 6vpm | A | B | adenosine monophosphate | Human | 12658 | |
| AURKA (AurA) | Aur | Other | 2c6e | A | | n-{5-[(7-{[(2s)-2-hydroxy-3-piperidin-1-ylpropyl]oxy}-6-methoxyquinazolin-4-yl)amino]pyrimidin-2-yl}benzamide | Human | 1989 | |
| GAK | NAK | Other | 4y8d | B | B | 2-methoxy-4-[3-(morpholin-4-yl)[1,2]thiazolo[4,3-b]pyridin-6-yl]aniline | Human | 342 | |
| GAK | NAK | Other | 4c57 | B | B | (2z,3e)-2,3'-biindole-2',3(1h,1'h)-dione 3-{o-[(3r)-3,4-dihydroxybutyl]oxime} | Human | 348 | |
| AURKA (AurA) | Aur | Other | 5dn3 | A | B | adenosine-5'-triphosphate | Human | 6818 | |
| TBK1 | IKK | Other | 6cq0 | A | | 2-amino-7-[3-(dimethylamino)propyl]-5-oxo-5h-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid | Human | 10756 | |
| AURKA (AurA) | Aur | Other | 6vpl | B | B | phosphoaminophosphonic acid-adenylate ester | Human | 12668 | |
| AURKA (AurA) | Aur | Other | 2wtv | B | A | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 2037 | |
| AURKA (AurA) | Aur | Other | 4ded | A | | 2-({2-[(4-carbamoylphenyl)amino]pyrimidin-4-yl}amino)benzamide | Human | 2043 | |
| HASPIN (Haspin) | Haspin | Other | 6z56 | A | C | 6-(2-methoxyethoxy)-11-methyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one | Human | 12320 | |
| HASPIN (Haspin) | Haspin | Other | 6g37 | A | B | 5-fluorotubercidin | Human | 9845 | |
| HASPIN (Haspin) | Haspin | Other | 4qtc | A | A | (3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamide | Human | 3805 | |
| AURKA (AurA) | Aur | Other | 4j8n | C | | - | Human | 2007 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6cmj | A | B | 2-(2-methylpropyl)-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9783 | |
| AURKA (AurA) | Aur | Other | 3w2c | G | | 2-{4-[3-(1h-benzimidazol-2-yl)-1h-indazol-6-yl]-1h-pyrazol-1-yl}-n-(3-methylbutyl)acetamide | Human | 2026 | |
| AURKA (AurA) | Aur | Other | 3m11 | A | | 1-(4-{2-[(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amino]ethyl}phenyl)-3-phenylurea | Human | 2036 | |
| AURKA (AurA) | Aur | Other | 3myg | A | | 2-{ethyl[(5-{[6-methyl-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}isothiazol-3-yl)methyl]amino}-2-methylpropan-1-ol | Human | 2065 | |
| ERN1 (IRE1) | IRE | Other | 6w3k | A | | 4-[5-[2,6-bis(fluoranyl)phenyl]-2~{h}-pyrazolo[3,4-b]pyridin-3-yl]-2-(4-oxidanylpiperidin-1-yl)-1~{h}-pyrimidin-6-one | Human | 13123 | |
| ERN1 (IRE1) | IRE | Other | 6xdb | A | | 4-amino-n-(6-chloro-2-fluoro-3-{[(2-fluorophenyl)sulfonyl]amino}phenyl)-6-(1,3-dimethyl-1h-pyrazol-4-yl)quinazoline-8-carboxamide | Human | 13531 | |
| AURKA (AurA) | Aur | Other | 3e5a | A | | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 2006 | |
| ERN1 (IRE1) | IRE | Other | 6urc | B | | 2-chloro-n-(6-methyl-5-{[3-(2-{[(3s)-piperidin-3-yl]amino}pyrimidin-4-yl)pyridin-2-yl]oxy}naphthalen-1-yl)benzene-1-sulfonamide | Human | 11798 | |
| AURKA (AurA) | Aur | Other | 3fdn | A | | n-[3-(acetylamino)phenyl]-5-{(2e)-2-[(4-methoxyphenyl)methylidene]hydrazino}-3-methyl-1h-pyrazole-4-carboxamide | Human | 1973 | |
| WNK3 (Wnk3) | WNK | Other | 9d7q | A | | - | Human | 15402 | |
| AURKA (AurA) | Aur | Other | 8c1i | A | B | adenosine-5'-diphosphate | Human | 15139 | |
| AURKA (AurA) | Aur | Other | 8c1d | A | B | adenosine-5'-diphosphate | Human | 15138 | |
| CDC7 | CDC7 | Other | 6ya8 | A | A | adenosine-5'-diphosphate | Human | 13846 | |
| GAK | NAK | Other | 4c57 | A | B | (2z,3e)-2,3'-biindole-2',3(1h,1'h)-dione 3-{o-[(3r)-3,4-dihydroxybutyl]oxime} | Human | 340 | |
| GAK | NAK | Other | 4c57 | B | A | (2z,3e)-2,3'-biindole-2',3(1h,1'h)-dione 3-{o-[(3r)-3,4-dihydroxybutyl]oxime} | Human | 334 | |
| GAK | NAK | Other | 4c59 | A | B | (2z,3e)-2,3'-biindole-2',3(1h,1'h)-dione 3-{o-[(3r)-3,4-dihydroxybutyl]oxime} | Human | 346 | |
| GAK | NAK | Other | 5y80 | A | A | gefitinib | Human | 10329 | |
| AURKA (AurA) | Aur | Other | 6z4y | A | B | 6-(2-methoxyethoxy)-11-methyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one | Human | 12307 | |
| GAK | NAK | Other | 4y8d | A | A | 2-methoxy-4-[3-(morpholin-4-yl)[1,2]thiazolo[4,3-b]pyridin-6-yl]aniline | Human | 344 | |
| GAK | NAK | Other | 4c59 | A | A | (2z,3e)-2,3'-biindole-2',3(1h,1'h)-dione 3-{o-[(3r)-3,4-dihydroxybutyl]oxime} | Human | 337 | |
| GAK | NAK | Other | 5y7z | A | | gefitinib | Human | 10332 | |
| GAK | NAK | Other | 4c57 | A | A | (2z,3e)-2,3'-biindole-2',3(1h,1'h)-dione 3-{o-[(3r)-3,4-dihydroxybutyl]oxime} | Human | 341 | |
| PLK1 | PLK | Other | 5ta6 | A | B | 4-{[(6r)-7-cyano-5-cyclopentyl-6-ethyl-5,6-dihydroimidazo[1,5-f]pteridin-3-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 7462 | |
| TBK1 | IKK | Other | 4eut | A | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 609 | |
| BUB1 | BUB | Other | 6f7b | A | B | 2-[3,5-bis(fluoranyl)-4-[[3-[5-methoxy-4-[(3-methoxypyridin-4-yl)amino]pyrimidin-2-yl]indazol-1-yl]methyl]phenoxy]ethanol | Human | 10807 | |
| ERN1 (IRE1) | IRE | Other | 3p23 | A | | adenosine-5'-diphosphate | Human | 1795 | |
| AURKA (AurA) | Aur | Other | 2xne | A | | 3-chloro-n-(4-morpholin-4-ylphenyl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine | Human | 7221 | |
| AURKA (AurA) | Aur | Other | 6vpi | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 12669 | |
| AURKA (AurA) | Aur | Other | 5os5 | A | A | adenosine-5'-diphosphate | Human | 8647 | |
| AURKA (AurA) | Aur | Other | 2bmc | A | | (3e)-n-(2,6-diethylphenyl)-3-{[4-(4-methylpiperazin-1-yl)benzoyl]imino}pyrrolo[3,4-c]pyrazole-5(3h)-carboxamide | Human | 2015 | |
| AURKA (AurA) | Aur | Other | 6c83 | A | | phosphomethylphosphonic acid adenylate ester | Human | 10934 | |
| AURKA (AurA) | Aur | Other | 5l8j | A | B | adenosine-5'-diphosphate | Human | 6812 | |
| AURKA (AurA) | Aur | Other | 3w16 | A | | 4-[(5-methyl-1h-pyrazol-3-yl)amino]-2-phenylphthalazin-1(2h)-one | Human | 2012 | |
| ERN1 (IRE1) | IRE | Other | 4yzd | C | B | adenosine-5'-diphosphate | Human | 6226 | |
| AURKA (AurA) | Aur | Other | 3uoh | A | | 4-({4-[(2-bromophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | Human | 2077 | |
| AURKA (AurA) | Aur | Other | 4j8n | B | | - | Human | 2061 | |
| PLK1 | PLK | Other | 2rku | A | A | 4-{[(7r)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 4969 | |
| AURKA (AurA) | Aur | Other | 8c14 | A | A | adenosine-5'-diphosphate | Human | 15143 | |
| AURKA (AurA) | Aur | Other | 8c1g | A | | adenosine-5'-diphosphate | Human | 15148 | |
| AURKA (AurA) | Aur | Other | 5orv | A | | adenosine-5'-diphosphate | Human | 8643 | |
| WNK3 (Wnk3) | WNK | Other | 5o23 | B | B | - | Human | 8166 | |
| WNK3 (Wnk3) | WNK | Other | 5o2b | B | A | 1-cyclopentyl-3-(1h-pyrrolo[2,3-b]pyridin-5-yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine | Human | 8154 | |
| AURKA (AurA) | Aur | Other | 5dpv | A | B | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 6826 | |
| TTK | TTK | Other | 5n7v | A | | ~{n}6-cyclohexyl-~{n}2-(2-methyl-4-morpholin-4-yl-phenyl)-7~{h}-purine-2,6-diamine | Human | 7978 | |
| TTK | TTK | Other | 4bi1 | A | | thieno[3,2-c][2,6]naphthyridine | Human | 4699 | |
| ERN1 (IRE1) | IRE | Other | 3p23 | B | | adenosine-5'-diphosphate | Human | 1797 | |
| AAK1 | NAK | Other | 5te0 | A | | methyl (3z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1h-indole-6-carboxylate | Human | 7156 | |
| ERN1 (IRE1) | IRE | Other | 3p23 | C | | adenosine-5'-diphosphate | Human | 1798 | |
| ERN1 (IRE1) | IRE | Other | 4z7h | A | | 2-methoxy-4-[6-(propan-2-ylamino)imidazo[1,2-b]pyridazin-3-yl]benzamide | Human | 1794 | |
| TTK | TTK | Other | 5ljj | A | | n~6~-cyclohexyl-n~2~-(4-morpholin-4-ylphenyl)-9h-purine-2,6-diamine | Human | 7092 | |
| WEE1 (Wee1) | WEE | Other | 7n3u | A | | 1-[(7r)-7-ethyl-7-hydroxy-7h-cyclopenta[b]pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-(prop-2-en-1-yl)-1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-one | Human | 13857 | |
| TTK | TTK | Other | 3h9f | A | A | 9-cyclopentyl-2-(4-(4-hydroxypiperidin-1-yl)-2-methoxyphenylamino)-5-methyl-8,9-dihydro-5h-pyrimido[4,5-b][1,4]diazepin-6(7h)-one | Human | 4701 | |
| HASPIN (Haspin) | Haspin | Other | 6z5d | A | B | 11-methyl-8,11,14,18,19,22-hexazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2(23),3,5,15(22),16,19-heptaen-7-one | Human | 12330 | |
| HASPIN (Haspin) | Haspin | Other | 6z5b | A | A | 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one | Human | 12331 | |
| HASPIN (Haspin) | Haspin | Other | 6g3a | A | B | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 9835 | |
| WNK3 (Wnk3) | WNK | Other | 5o23 | A | A | - | Human | 8151 | |
| WNK3 (Wnk3) | WNK | Other | 5o1v | A | A | - | Human | 8157 | |
| ERN1 (IRE1) | IRE | Other | 4yzc | A | A | staurosporine | Human | 6235 | |
| ERN1 (IRE1) | IRE | Other | 6w3e | B | | methyl ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]carbamate | Human | 13126 | |
| HASPIN (Haspin) | Haspin | Other | 6g38 | A | B | '2-(4-amino-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol | Human | 9842 | |
| ERN1 (IRE1) | IRE | Other | 3p23 | D | | adenosine-5'-diphosphate | Human | 1800 | |
| HASPIN (Haspin) | Haspin | Other | 2vuw | A | B | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 3801 | |
| AURKA (AurA) | Aur | Other | 8c1k | A | | adenosine-5'-diphosphate | Human | 15146 | |
| HASPIN (Haspin) | Haspin | Other | 2wb8 | A | B | - | Human | 3815 | |
| HASPIN (Haspin) | Haspin | Other | 7ops | A | | 2-methylsulfanyl-10-nitro-pyrido[3,4-g]quinazoline | Human | 13815 | |
| HASPIN (Haspin) | Haspin | Other | 7sqm | A | A | 1-[(4s)-5-(2,4-difluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-4-methylpiperidin-4-amine | Human | 14033 | |
| HASPIN (Haspin) | Haspin | Other | 6g34 | A | B | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 9846 | |
| HASPIN (Haspin) | Haspin | Other | 6g39 | A | C | - | Human | 9838 | |
| HASPIN (Haspin) | Haspin | Other | 6z56 | A | B | 6-(2-methoxyethoxy)-11-methyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one | Human | 12333 | |
| HASPIN (Haspin) | Haspin | Other | 6z5b | A | B | 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one | Human | 12334 | |
| PAN3 | PAN3 | Other | 9qtu | A | | - | Human | 15438 | |
| TP53RK (PRPK) | Bud32 | Other | 7sza | A | B | 4-amino-2-[(3r)-2,6-dioxopiperidin-3-yl]-1h-isoindole-1,3(2h)-dione | Human | 14599 | |
| ERN1 (IRE1) | IRE | Other | 9n88 | A | | - | Human | 15450 | |
| ERN1 (IRE1) | IRE | Other | 9gow | A | | 3-[5-bromanyl-2-methyl-1-(phenylcarbonyl)indol-3-yl]propanoic acid | Human | 15451 | |
| PLK1 | PLK | Other | 22rd | A | | 1-(2-hydroxyethyl)-8-[[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino]-4,5-dihydropyrimido[5,4-g]indazole-3-carboxamide | Human | 15471 | |
| GAK | NAK | Other | 4o38 | B | A | - | Human | 338 | |
| TP53RK (PRPK) | Bud32 | Other | 7sza | A | A | 4-amino-2-[(3r)-2,6-dioxopiperidin-3-yl]-1h-isoindole-1,3(2h)-dione | Human | 14597 | |
| AURKA (AurA) | Aur | Other | 9qvz | A | B | adenosine-5'-diphosphate | Human | 15482 | |
| AURKA (AurA) | Aur | Other | 9rvk | B | A | adenosine-5'-diphosphate | Human | 15483 | |
| AURKA (AurA) | Aur | Other | 9kds | A | | - | Human | 15484 | |
| AURKA (AurA) | Aur | Other | 9qvz | A | A | adenosine-5'-diphosphate | Human | 15485 | |
| AURKA (AurA) | Aur | Other | 9s7t | A | | adenosine-5'-diphosphate | Human | 15486 | |
| AURKA (AurA) | Aur | Other | 5dt0 | A | B | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 6803 | |
| CDC7 | CDC7 | Other | 4f99 | A | | adenosine-5'-diphosphate | Human | 4824 | |
| GAK | NAK | Other | 5y7z | B | | gefitinib | Human | 10331 | |
| AURKA (AurA) | Aur | Other | 9ks6 | A | | - | Human | 15487 | |
| PKMYT1 (MYT1) | WEE | Other | 8zud | A | | 2-azanyl-3-(2,6-dimethyl-3-oxidanyl-phenyl)-5-(2-morpholin-4-ylpyridin-4-yl)benzamide | Human | 15524 | |
| PKMYT1 (MYT1) | WEE | Other | 8ztx | A | | 2-azanyl-3-(2,6-dimethyl-3-oxidanyl-phenyl)-5-pyridin-4-yl-benzamide | Human | 15525 | |
| TBK1 | IKK | Other | 4euu | B | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 606 | |
| AURKA (AurA) | Aur | Other | 5dnr | A | A | adenosine-5'-triphosphate | Human | 6810 | |
| PKMYT1 (MYT1) | WEE | Other | 9lgl | A | | 3-azanyl-7-chloranyl-4-(2-methyl-5-oxidanyl-phenyl)-1h-1,5-naphthyridin-2-one | Human | 15526 | |
| PKMYT1 (MYT1) | WEE | Other | 9lid | A | | 4-[7-azanyl-8-(7-fluoranyl-1h-indazol-4-yl)-6-oxidanylidene-5h-1,5-naphthyridin-3-yl]-n,n-dimethyl-benzamide | Human | 15527 | |
| AURKA (AurA) | Aur | Other | 4dee | A | | adenosine-5'-diphosphate | Human | 1952 | |
| NEK7 | NEK | Other | 8sxn | A | | - | Human | 15246 | |
| WEE1 (Wee1) | WEE | Other | 9d0q | A | | 1-[(6r)-6-(2,6-dichlorophenyl)-8-methyl-2-[4-(4-methylpiperazin-1-yl)anilino]-7,8-dihydropteridin-5(6h)-yl]ethan-1-one | Human | 15664 | |
| HASPIN (Haspin) | Haspin | Other | 8rdk | A | | 3-pyridin-4-yl-1~{h}-pyrrolo[3,2-g]isoquinoline | Human | 15259 | |
| ERN1 (IRE1) | IRE | Other | 6hx1 | A | B | 6-chloranyl-~{n}-(cyclopropylmethyl)-3-(2~{h}-indazol-5-yl)imidazo[1,2-b]pyridazin-8-amine | Human | 10929 | |
| ERN1 (IRE1) | IRE | Other | 6w3a | B | B | ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]but-2-ynamide | Human | 13119 | |
| ERN1 (IRE1) | IRE | Other | 6w3c | B | | - | Human | 13038 | |
| NEK7 | NEK | Other | 8ws0 | A | B | - | Human | 15995 | |
| NEK7 | NEK | Other | 9nfq | C | | adenosine-5'-diphosphate | Human | 15996 | |
| NEK7 | NEK | Other | 8ws1 | A | B | - | Human | 15997 | |
| NEK7 | NEK | Other | 8ws1 | A | A | - | Human | 15998 | |
| NEK7 | NEK | Other | 8ws0 | A | A | - | Human | 15999 | |
| AURKA (AurA) | Aur | Other | 5orr | A | | adenosine-5'-diphosphate | Human | 8636 | |
| AURKA (AurA) | Aur | Other | 6hjk | A | | (~{e})-~{n}-[4-(4-azanyl-1-propan-2-yl-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl]-4-[4-fluoranyl-3-(trifluoromethyl)phenyl]-4-oxidanylidene-but-2-enamide | Human | 10411 | |
| CHUK (IKKa) | IKK | Other | 5ebz | D | | 2-azanyl-5-phenyl-3-(4-sulfamoylphenyl)benzamide | Human | 7144 | |
| CHUK (IKKa) | IKK | Other | 5ebz | K | | 2-azanyl-5-phenyl-3-(4-sulfamoylphenyl)benzamide | Human | 7150 | |
| PINK1 | NKF2 | Other | 9kqn | C | | - | Human | 16220 | |
| PINK1 | NKF2 | Other | 9kox | D | | - | Human | 16221 | |
| PINK1 | NKF2 | Other | 9x4x | B | | - | Human | 16222 | |
| AAK1 | NAK | Other | 9qb5 | A | | ~{n}-(phenylmethyl)-7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.1^{2,6}.0^{17,20}]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxamide | Human | 16225 | |
| CHUK (IKKa) | IKK | Other | 5tqw | B | | - | Human | 7248 | |
| AURKA (AurA) | Aur | Other | 4ztq | A | | (2z,5z)-2-[(4-ethylphenyl)imino]-3-(2-methoxyethyl)-5-(pyridin-4-ylmethylidene)-1,3-thiazolidin-4-one | Human | 6804 | |
| AURKA (AurA) | Aur | Other | 1ol6 | A | | adenosine-5'-triphosphate | Human | 2081 | |
| ERN1 (IRE1) | IRE | Other | 6w3a | B | A | ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]but-2-ynamide | Human | 13118 | |
| AURKA (AurA) | Aur | Other | 5odt | A | B | adenosine-5'-diphosphate | Human | 9736 | |
| AURKA (AurA) | Aur | Other | 5orw | A | | adenosine-5'-diphosphate | Human | 8631 | |
| CHUK (IKKa) | IKK | Other | 5ebz | G | | 2-azanyl-5-phenyl-3-(4-sulfamoylphenyl)benzamide | Human | 7154 | |
| CHUK (IKKa) | IKK | Other | 5tqx | B | | - | Human | 7262 | |
| CHUK (IKKa) | IKK | Other | 5ebz | I | | 2-azanyl-5-phenyl-3-(4-sulfamoylphenyl)benzamide | Human | 7152 | |
| CHUK (IKKa) | IKK | Other | 5ebz | C | | 2-azanyl-5-phenyl-3-(4-sulfamoylphenyl)benzamide | Human | 7146 | |
| AURKA (AurA) | Aur | Other | 2w1e | A | | 4-[(2-{4-[(phenylcarbamoyl)amino]-1h-pyrazol-3-yl}-1h-benzimidazol-5-yl)methyl]morpholin-4-ium | Human | 2038 | |
| CHUK (IKKa) | IKK | Other | 5tqy | A | | - | Human | 7196 | |
| AURKA (AurA) | Aur | Other | 2j50 | A | | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 2001 | |
| PLK4 | PLK | Other | 3cok | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 1814 | |
| PLK4 | PLK | Other | 3cok | B | B | phosphoaminophosphonic acid-adenylate ester | Human | 1817 | |
| PLK4 | PLK | Other | 3cok | B | A | phosphoaminophosphonic acid-adenylate ester | Human | 1815 | |
| PLK4 | PLK | Other | 4yur | A | | 2-({2-fluoro-4-[(2-fluoro-3-nitrobenzyl)sulfonyl]phenyl}sulfanyl)-5-methoxy-n-(3-methyl-1h-pyrazol-5-yl)-6-(morpholin-4-yl)pyrimidin-4-amine | Human | 1813 | |
| HASPIN (Haspin) | Haspin | Other | 6g38 | A | A | '2-(4-amino-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol | Human | 9830 | |
| PEAK1 (SgK269) | NKF3 | Other | 6bhc | A | B | - | Human | 9067 | |
| PEAK1 (SgK269) | NKF3 | Other | 6bhc | A | A | - | Human | 9068 | |
| AURKA (AurA) | Aur | Other | 8ssp | A | A | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 14868 | |
| CHUK (IKKa) | IKK | Other | 5ebz | E | | 2-azanyl-5-phenyl-3-(4-sulfamoylphenyl)benzamide | Human | 7151 | |
| TBK1 | IKK | Other | 4im3 | A | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 622 | |
| PIK3R4 | VPS15 | Other | 9rxb | B | | - | Human | 15416 | |
| PIK3R4 | VPS15 | Other | 9mhg | A | | - | Human | 15417 | |
| PIK3R4 | VPS15 | Other | 9rx8 | B | | - | Human | 15418 | |
| PIK3R4 | VPS15 | Other | 9rx9 | B | | - | Human | 15419 | |
| PIK3R4 | VPS15 | Other | 9tw3 | B | | - | Human | 15420 | |
| TBK1 | IKK | Other | 4eut | B | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 617 | |
| PIK3R4 | VPS15 | Other | 9zpc | A | | - | Human | 15423 | |
| PIK3R4 | VPS15 | Other | 9rx6 | B | | - | Human | 15424 | |
| PIK3R4 | VPS15 | Other | 9rxa | B | | - | Human | 15425 | |
| PIK3R4 | VPS15 | Other | 13bv | D | | - | Human | 15426 | |
| PIK3R4 | VPS15 | Other | 9tz3 | B | | - | Human | 15427 | |
| PIK3R4 | VPS15 | Other | 9mhf | A | | - | Human | 15428 | |
| PIK3R4 | VPS15 | Other | 9mhh | A | | - | Human | 15429 | |
| PIK3R4 | VPS15 | Other | 7bl1 | C | | - | Human | 13360 | |
| PIK3R4 | VPS15 | Other | 9rx5 | B | | - | Human | 15430 | |
| PIK3R4 | VPS15 | Other | 9s47 | B | | - | Human | 15431 | |
| TBK1 | IKK | Other | 4im0 | A | A | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 610 | |
| IKBKB (IKKb) | IKK | Other | 8omv | A | | - | Human | 15271 | |
| PIK3R4 | VPS15 | Other | 9rx7 | B | | - | Human | 15432 | |
| PIK3R4 | VPS15 | Other | 9zpd | A | | - | Human | 15433 | |
| TBK1 | IKK | Other | 4im3 | A | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 619 | |
| TBK1 | IKK | Other | 6boe | A | | 2-amino-5-oxo-7-(propan-2-yl)-n-(1h-tetrazol-5-yl)-5h-[1]benzopyrano[2,3-b]pyridine-3-carboxamide | Human | 10371 | |
| CDC7 | CDC7 | Other | 4f9c | A | | 8-chloro-2-[(2s)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3h)-one | Human | 4823 | |
| AURKA (AurA) | Aur | Other | 5dr2 | A | | adenosine-5'-triphosphate | Human | 6825 | |
| AURKA (AurA) | Aur | Other | 3uo5 | A | | 4-{[4-(phenylamino)pyrimidin-2-yl]amino}benzoic acid | Human | 2045 | |
| AURKA (AurA) | Aur | Other | 2w1c | A | | 4-{[2-(4-{[(4-fluorophenyl)carbonyl]amino}-1h-pyrazol-3-yl)-1h-benzimidazol-6-yl]methyl}morpholin-4-ium | Human | 2027 | |
| HASPIN (Haspin) | Haspin | Other | 6g35 | A | A | 5-bromotubercidin | Human | 9843 | |
| AURKA (AurA) | Aur | Other | 5os3 | A | | adenosine-5'-diphosphate | Human | 8637 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6cmj | B | B | 2-(2-methylpropyl)-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9785 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6brc | A | | 5-chloro-n~2~-{4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl}-n~4~-[2-(dimethylphosphoryl)phenyl]pyrimidine-2,4-diamine | Human | 9062 | |
| AURKA (AurA) | Aur | Other | 5dr6 | A | A | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 6811 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5yv9 | A | | 5-chloro-2-methoxy-4[(1z)-3-(4-methoxyphenyl)-3-oxoprop-1-en-1-yl]aminobenzoic acid | Human | 10752 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 2zv2 | A | | 7-oxo-7h-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid | Human | 406 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6bqp | A | | 1-(2-{5-[(3-methyloxetan-3-yl)methoxy]-1h-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine | Human | 9064 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6bku | A | | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 8687 | |
| ERN1 (IRE1) | IRE | Other | 4z7g | A | | - | Human | 1799 | |
| ERN1 (IRE1) | IRE | Other | 6xdd | B | | 4-[(trans-4-aminocyclohexyl)amino]-n-(6-chloro-3-{[(2,5-difluorophenyl)sulfonyl]amino}-2-fluorophenyl)thieno[3,2-d]pyrimidine-7-carboxamide | Human | 13530 | |
| ERN1 (IRE1) | IRE | Other | 6w3c | D | | - | Human | 13037 | |
| ERN1 (IRE1) | IRE | Other | 6w39 | A | A | ethyl ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]carbamate | Human | 13120 | |
| ERN1 (IRE1) | IRE | Other | 6w3e | A | | methyl ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]carbamate | Human | 13121 | |
| ERN1 (IRE1) | IRE | Other | 4yzc | B | B | staurosporine | Human | 6231 | |
| ERN1 (IRE1) | IRE | Other | 6w39 | B | B | ethyl ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]carbamate | Human | 13124 | |
| ERN1 (IRE1) | IRE | Other | 6w3a | A | A | ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]but-2-ynamide | Human | 13125 | |
| ERN1 (IRE1) | IRE | Other | 4yz9 | B | B | (5r)-2-(3,4-dichlorobenzyl)-n-(4-methylbenzyl)-2,7-diazaspiro[4.5]decane-7-carboxamide | Human | 6229 | |
| AURKA (AurA) | Aur | Other | 3h0z | C | | 4-{[2-({4-[2-(4-acetylpiperazin-1-yl)-2-oxoethyl]phenyl}amino)-5-fluoropyrimidin-4-yl]amino}-n-(2-chlorophenyl)benzamide | Human | 2063 | |
| AURKA (AurA) | Aur | Other | 2j4z | B | | 4-(4-methylpiperazin-1-yl)-n-[5-(2-thienylacetyl)-1,5-dihydropyrrolo[3,4-c]pyrazol-3-yl]benzamide | Human | 1990 | |
| PLK2 | PLK | Other | 4i5m | A | | 4-{[(7r)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 5557 | |
| AURKA (AurA) | Aur | Other | 3vap | A | | 3-(1-{2-[(3-fluoropyridinium-4-yl)amino]-2-oxoethyl}-1h-pyrazol-4-yl)-6-methyl-8-[(3-{[(1r,3r)-3-methylpiperidinium-1-yl]methyl}-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-1-ium | Human | 2029 | |
| EIF2AK2 (PKR) | PEK | Other | 6d3k | B | | adenosine-5'-diphosphate | Human | 11385 | |
| AURKA (AurA) | Aur | Other | 6vpm | A | A | adenosine monophosphate | Human | 12661 | |
| ULK2 | ULK | Other | 6yid | D | B | 2-({5-bromo-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}oxy)-n-methylbenzene-1-carboximidic acid | Human | 12383 | |
| PLK1 | PLK | Other | 2yac | A | | 1-(2-hydroxyethyl)-8-[[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino]-4,5-dihydropyrimido[5,4-g]indazole-3-carboxamide | Human | 4957 | |
| PLK1 | PLK | Other | 3thb | A | | 9-chloro-2-({5-[3-(dimethylamino)propyl]-2-methylpyridin-3-yl}amino)-5,7-dihydro-6h-pyrimido[5,4-d][1]benzazepine-6-thione | Human | 4968 | |
| PLK1 | PLK | Other | 3fc2 | A | B | n-{trans-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}-4-{[(7r)-7-ethyl-5-methyl-8-(1-methylethyl)-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzamide | Human | 4967 | |
| AURKA (AurA) | Aur | Other | 5osf | A | | adenosine-5'-diphosphate | Human | 8640 | |
| TTK | TTK | Other | 5ehy | A | | 4-(furan-3-yl)-3-phenyl-2~{h}-pyrazolo[4,3-c]pyridine | Human | 6556 | |
| AURKA (AurA) | Aur | Other | 5one | A | B | 4-(propanoylamino)-~{n}-[4-[(5,8,11-trimethyl-6-oxidanylidene-pyrimido[4,5-b][1,4]benzodiazepin-2-yl)amino]phenyl]benzamide | Human | 8370 | |
| TTK | TTK | Other | 7chn | A | | 4-(cyclohexylamino)-2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | 13552 | |
| AURKA (AurA) | Aur | Other | 7o2v | A | | 1-[[3,4-bis(fluoranyl)phenyl]methyl]-~{n}-[(1~{r})-2-[[(3~{e})-3-(1~{h}-imidazol-5-ylmethylidene)-2-oxidanylidene-1~{h}-indol-5-yl]amino]-2-oxidanylidene-1-phenyl-ethyl]-6-methyl-2-oxidanylidene-pyridine-3-carboxamide | Human | 13947 | |
| AURKA (AurA) | Aur | Other | 4dhf | B | | 7-cyclopentyl-2-({1-methyl-5-[(4-methylpiperazin-1-yl)carbonyl]-1h-pyrrol-3-yl}amino)-7h-pyrrolo[2,3-d]pyrimidine-6-carboxamide | Human | 1982 | |
| AURKA (AurA) | Aur | Other | 5drd | A | | adenosine-5'-triphosphate | Human | 6823 | |
| AURKA (AurA) | Aur | Other | 6hjj | A | A | ~{n}-[4-(4-azanyl-1-propan-2-yl-pyrazolo[3,4-d]pyrimidin-3-yl)-3-methyl-phenyl]-4-[4-fluoranyl-3-(trifluoromethyl)phenyl]-4-oxidanylidene-butanamide | Human | 10410 | |
| AURKA (AurA) | Aur | Other | 1muo | A | | adenosine | Human | 2062 | |
| AURKA (AurA) | Aur | Other | 5l8l | A | B | adenosine-5'-diphosphate | Human | 6824 | |
| AURKA (AurA) | Aur | Other | 3coh | A | | 8-ethyl-3,10,10-trimethyl-4,5,6,8,10,12-hexahydropyrazolo[4',3':6,7]cyclohepta[1,2-b]pyrrolo[2,3-f]indol-9(1h)-one | Human | 1963 | |
| PKMYT1 (MYT1) | WEE | Other | 8d6f | A | | (1m)-2-amino-1-(5-hydroxy-2-methylphenyl)-1h-pyrrolo[2,3-b]quinoxaline-3-carboxamide | Human | 14297 | |
| PLK1 | PLK | Other | 2rku | A | B | 4-{[(7r)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 4966 | |
| CHUK (IKKa) | IKK | Other | 5tqx | A | | - | Human | 7261 | |
| PKMYT1 (MYT1) | WEE | Other | 8d6e | A | B | (1p)-2-amino-1-(3-hydroxy-2,6-dimethylphenyl)-5,6-dimethyl-1h-pyrrolo[2,3-b]pyridine-3-carboxamide | Human | 14293 | |
| ULK1 | ULK | Other | 4wnp | B | B | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1879 | |
| PLK1 | PLK | Other | 2owb | A | B | 4-(4-methylpiperazin-1-yl)-n-[5-(2-thienylacetyl)-1,5-dihydropyrrolo[3,4-c]pyrazol-3-yl]benzamide | Human | 4958 | |
| CHUK (IKKa) | IKK | Other | 5tqw | A | | - | Human | 7249 | |
| PLK1 | PLK | Other | 4j53 | A | A | 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5h-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 4975 | |
| CHUK (IKKa) | IKK | Other | 5ebz | L | | 2-azanyl-5-phenyl-3-(4-sulfamoylphenyl)benzamide | Human | 7147 | |
| CHUK (IKKa) | IKK | Other | 5ebz | A | | 2-azanyl-5-phenyl-3-(4-sulfamoylphenyl)benzamide | Human | 7153 | |
| CHUK (IKKa) | IKK | Other | 5ebz | B | | 2-azanyl-5-phenyl-3-(4-sulfamoylphenyl)benzamide | Human | 7145 | |
| CHUK (IKKa) | IKK | Other | 5ebz | F | | 2-azanyl-5-phenyl-3-(4-sulfamoylphenyl)benzamide | Human | 7149 | |
| PLK1 | PLK | Other | 2v5q | B | B | - | Human | 4961 | |
| TBK1 | IKK | Other | 4iw0 | A | | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 608 | |
| TBK1 | IKK | Other | 5w5v | A | | 2-amino-7-(1-methylethyl)-5-oxo-5h-chromeno[2,3-b]pyridine-3-carboxylic acid | Human | 10024 | |
| TBK1 | IKK | Other | 6cq4 | A | | 2-amino-7-(4,4-difluorocyclohexyl)-5-oxo-5h-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid | Human | 10757 | |
| TBK1 | IKK | Other | 6o8b | B | | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 11054 | |
| TBK1 | IKK | Other | 6bny | A | | 2-amino-7-(propan-2-yl)-3-(1h-tetrazol-5-yl)-5h-[1]benzopyrano[2,3-b]pyridin-5-one | Human | 10369 | |
| TBK1 | IKK | Other | 6nt9 | A | | - | Human | 10940 | |
| PLK1 | PLK | Other | 2v5q | A | A | - | Human | 4970 | |
| PLK1 | PLK | Other | 5ta6 | A | C | 4-{[(6r)-7-cyano-5-cyclopentyl-6-ethyl-5,6-dihydroimidazo[1,5-f]pteridin-3-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 7463 | |
| AURKA (AurA) | Aur | Other | 6vpj | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 12654 | |
| AURKA (AurA) | Aur | Other | 5aad | A | | 7-(1-benzyl-1h-pyrazol-4-yl)-6-chloro-2-(1,3-dimethyl-1h-pyrazol-4-yl)-3h-imidazo[4,5-b]pyridine | Human | 6011 | |
| AURKA (AurA) | Aur | Other | 2bmc | D | | (3e)-n-(2,6-diethylphenyl)-3-{[4-(4-methylpiperazin-1-yl)benzoyl]imino}pyrrolo[3,4-c]pyrazole-5(3h)-carboxamide | Human | 1984 | |
| AURKA (AurA) | Aur | Other | 7ayh | A | | 7-[2-[(4-methoxyphenyl)amino]pyrimidin-4-yl]-1,3,4,5-tetrahydro-1-benzazepin-2-one | Human | 13228 | |
| AURKA (AurA) | Aur | Other | 2x6d | A | A | 6-bromo-7-[4-(4-chlorobenzyl)piperazin-1-yl]-2-[4-(morpholin-4-ylmethyl)phenyl]-3h-imidazo[4,5-b]pyridine | Human | 1978 | |
| AURKA (AurA) | Aur | Other | 3h0z | A | | 4-{[2-({4-[2-(4-acetylpiperazin-1-yl)-2-oxoethyl]phenyl}amino)-5-fluoropyrimidin-4-yl]amino}-n-(2-chlorophenyl)benzamide | Human | 1970 | |
| AURKA (AurA) | Aur | Other | 9s0w | A | | adenosine-5'-diphosphate | Human | 15488 | |
| AURKA (AurA) | Aur | Other | 6vph | A | B | dithiane diol | Human | 12655 | |
| AURKA (AurA) | Aur | Other | 8jmx | A | | 5-(4-morpholin-4-yl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-2-oxidanyl-benzaldehyde | Human | 14864 | |
| AURKA (AurA) | Aur | Other | 6vpi | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 12656 | |
| AURKA (AurA) | Aur | Other | 5ew9 | A | B | 4-(3-chloranyl-2-fluoranyl-phenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid | Human | 6360 | |
| AURKA (AurA) | Aur | Other | 3uol | B | | n~4~-(2-chlorophenyl)-n~2~-[4-(1h-tetrazol-5-yl)phenyl]pyrimidine-2,4-diamine | Human | 2051 | |
| AURKA (AurA) | Aur | Other | 9suy | A | | adenosine-5'-diphosphate | Human | 15489 | |
| AURKA (AurA) | Aur | Other | 8ssp | A | B | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 14865 | |
| AURKA (AurA) | Aur | Other | 5odt | A | A | adenosine-5'-diphosphate | Human | 9738 | |
| AURKA (AurA) | Aur | Other | 2x6d | A | B | 6-bromo-7-[4-(4-chlorobenzyl)piperazin-1-yl]-2-[4-(morpholin-4-ylmethyl)phenyl]-3h-imidazo[4,5-b]pyridine | Human | 1975 | |
| AURKA (AurA) | Aur | Other | 5l8k | A | B | adenosine-5'-diphosphate | Human | 6813 | |
| AURKA (AurA) | Aur | Other | 3o50 | B | | n-{3-methyl-4-[(3-pyrimidin-4-ylpyridin-2-yl)oxy]phenyl}-3-(trifluoromethyl)benzamide | Human | 2067 | |
| AURKA (AurA) | Aur | Other | 9s0k | B | | adenosine-5'-diphosphate | Human | 15490 | |
| AURKA (AurA) | Aur | Other | 7ztl | A | B | adenosine-5'-diphosphate | Human | 14581 | |
| AURKA (AurA) | Aur | Other | 5orz | A | A | adenosine-5'-diphosphate | Human | 8639 | |
| AURKA (AurA) | Aur | Other | 3up7 | A | | 2-({2-[(4-carboxyphenyl)amino]pyrimidin-4-yl}amino)benzoic acid | Human | 2025 | |
| AURKA (AurA) | Aur | Other | 5aae | A | | 3-((4-(6-chloro-2-(1,3-dimethyl-1h-pyrazol-4-yl)-3h-imidazo[4,5-b]pyridin-7-yl)-1h-pyrazol-1-yl)methyl)-5-methylisoxazole | Human | 6012 | |
| AURKA (AurA) | Aur | Other | 5orz | A | B | adenosine-5'-diphosphate | Human | 8650 | |
| AURKA (AurA) | Aur | Other | 9rvk | B | B | adenosine-5'-diphosphate | Human | 15491 | |
| AURKA (AurA) | Aur | Other | 4jaj | A | | benzo[c][1,8]naphthyridin-6(5h)-one | Human | 2040 | |
| AURKA (AurA) | Aur | Other | 4j8n | A | | - | Human | 2028 | |
| AURKA (AurA) | Aur | Other | 5ew9 | A | A | 4-(3-chloranyl-2-fluoranyl-phenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid | Human | 6359 | |
| AURKA (AurA) | Aur | Other | 9sv0 | B | A | adenosine-5'-diphosphate | Human | 15492 | |
| AURKA (AurA) | Aur | Other | 4dea | A | | 4,4'-(pyrimidine-2,4-diyldiimino)dibenzoic acid | Human | 2064 | |
| AURKA (AurA) | Aur | Other | 3nrm | A | | n-(3-methylisothiazol-5-yl)-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine | Human | 2052 | |
| AURKA (AurA) | Aur | Other | 4uzd | B | | ethyl (9s)-9-[3-(1h-benzimidazol-2-yloxy)phenyl]-8-oxo-4,5,6,7,8,9-hexahydro-2h-pyrrolo[3,4-b]quinoline-3-carboxylate | Human | 1968 | |
| TP53RK (PRPK) | Bud32 | Other | 6wqx | D | | phosphoaminophosphonic acid-adenylate ester | Human | 13339 | |
| AURKA (AurA) | Aur | Other | 6cpe | A | A | - | Human | 10036 | |
| PLK1 | PLK | Other | 3kb7 | A | | 8-{[2-methoxy-5-(4-methylpiperazin-1-yl)phenyl]amino}-1-methyl-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 4962 | |
| AURKA (AurA) | Aur | Other | 3unz | A | | 4-({4-[(2-fluorophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | Human | 1972 | |
| AURKA (AurA) | Aur | Other | 8c1h | A | B | adenosine-5'-diphosphate | Human | 15142 | |
| AURKA (AurA) | Aur | Other | 9s1g | B | | adenosine-5'-diphosphate | Human | 15494 | |
| PLK1 | PLK | Other | 2owb | A | A | 4-(4-methylpiperazin-1-yl)-n-[5-(2-thienylacetyl)-1,5-dihydropyrrolo[3,4-c]pyrazol-3-yl]benzamide | Human | 4974 | |
| AURKA (AurA) | Aur | Other | 8c1e | A | | adenosine-5'-triphosphate | Human | 15145 | |
| AURKA (AurA) | Aur | Other | 3unz | B | | 4-({4-[(2-fluorophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | Human | 2049 | |
| AURKA (AurA) | Aur | Other | 4b0g | A | A | 6-bromo-2-(1-methyl-1h-imidazol-5-yl)-7-{4-[(5-methyl-1,2-oxazol-3-yl)methyl]piperazin-1-yl}-1h-imidazo[4,5-b]pyridine | Human | 2082 | |
| AURKA (AurA) | Aur | Other | 4c3p | A | | phosphomethylphosphonic acid adenylate ester | Human | 2018 | |
| AURKA (AurA) | Aur | Other | 6vpl | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 12662 | |
| AURKA (AurA) | Aur | Other | 8of5 | A | | adenosine-5'-diphosphate | Human | 15218 | |
| AURKA (AurA) | Aur | Other | 9sv0 | B | B | adenosine-5'-diphosphate | Human | 15496 | |
| AURKA (AurA) | Aur | Other | 3w18 | A | | 2-{3-[3-(1h-benzimidazol-2-yl)-1h-indazol-6-yl]-1h-pyrazol-5-yl}-n-(3-fluorophenyl)acetamide | Human | 1961 | |
| EIF2AK2 (PKR) | PEK | Other | 6d3k | A | | adenosine-5'-diphosphate | Human | 11386 | |
| EIF2AK2 (PKR) | PEK | Other | 8qel | B | | (3~{z})-3-[(4-methyl-1~{h}-imidazol-5-yl)methylidene]-2-oxidanylidene-1~{h}-indole-5-carboxamide | Human | 14954 | |
| EIF2AK2 (PKR) | PEK | Other | 2a19 | B | | phosphoaminophosphonic acid-adenylate ester | Human | 920 | |
| AURKA (AurA) | Aur | Other | 2wtv | C | B | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 2016 | |
| AURKA (AurA) | Aur | Other | 5dos | A | | adenosine-5'-triphosphate | Human | 6807 | |
| AURKA (AurA) | Aur | Other | 5os1 | A | B | adenosine-5'-diphosphate | Human | 8630 | |
| AURKA (AurA) | Aur | Other | 3uo6 | A | | 4-({4-[(2-chlorophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | Human | 1985 | |
| AURKA (AurA) | Aur | Other | 6z4y | A | A | 6-(2-methoxyethoxy)-11-methyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one | Human | 12306 | |
| AURKA (AurA) | Aur | Other | 5one | A | A | 4-(propanoylamino)-~{n}-[4-[(5,8,11-trimethyl-6-oxidanylidene-pyrimido[4,5-b][1,4]benzodiazepin-2-yl)amino]phenyl]benzamide | Human | 8371 | |
| AURKA (AurA) | Aur | Other | 2bmc | F | | (3e)-n-(2,6-diethylphenyl)-3-{[4-(4-methylpiperazin-1-yl)benzoyl]imino}pyrrolo[3,4-c]pyrazole-5(3h)-carboxamide | Human | 1993 | |
| AURKA (AurA) | Aur | Other | 3up2 | A | | 4-[(4-{[2-(trifluoromethoxy)phenyl]amino}pyrimidin-2-yl)amino]benzoic acid | Human | 2005 | |
| EIF2AK2 (PKR) | PEK | Other | 3uiu | B | | - | Human | 916 | |
| PLK1 | PLK | Other | 2ou7 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 4956 | |
| AURKA (AurA) | Aur | Other | 3w2c | A | | 2-{4-[3-(1h-benzimidazol-2-yl)-1h-indazol-6-yl]-1h-pyrazol-1-yl}-n-(3-methylbutyl)acetamide | Human | 2066 | |
| AURKA (AurA) | Aur | Other | 5ory | A | | adenosine-5'-diphosphate | Human | 8627 | |
| AURKA (AurA) | Aur | Other | 2wtv | A | B | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 1997 | |
| AURKA (AurA) | Aur | Other | 3w18 | B | | 2-{3-[3-(1h-benzimidazol-2-yl)-1h-indazol-6-yl]-1h-pyrazol-5-yl}-n-(3-fluorophenyl)acetamide | Human | 1967 | |
| AURKA (AurA) | Aur | Other | 9bzg | A | A | 7-cyclopentyl-n,n-dimethyl-2-[4-(methylcarbamoyl)anilino]-7h-pyrrolo[2,3-d]pyrimidine-6-carboxamide | Human | 15497 | |
| AURKA (AurA) | Aur | Other | 7fic | A | A | 6-[(5-cyclopropyl-1~{h}-pyrazol-3-yl)amino]-2-[4-[(3-methyl-4-oxidanyl-phenyl)methyl]piperazin-1-yl]-~{n}-prop-2-ynyl-pyrimidine-4-carboxamide | Human | 14234 | |
| AURKA (AurA) | Aur | Other | 4deb | A | | 4-[(4-{[3-(trifluoromethyl)phenyl]amino}pyrimidin-2-yl)amino]benzamide | Human | 1996 | |
| AAK1 | NAK | Other | 5l4q | B | A | ~{n}-[5-(4-cyanophenyl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide | Human | 6680 | |
| AURKA (AurA) | Aur | Other | 5dnr | A | B | adenosine-5'-triphosphate | Human | 6809 | |
| AURKA (AurA) | Aur | Other | 6c2t | A | A | (2s,4r)-1-[(3-chloro-2-fluorophenyl)methyl]-2-methyl-4-({3-[(1,3-thiazol-2-yl)amino]isoquinolin-1-yl}methyl)piperidine-4-carboxylic acid | Human | 10866 | |
| CDC7 | CDC7 | Other | 6ya7 | A | A | adenosine-5'-diphosphate | Human | 13845 | |
| CDC7 | CDC7 | Other | 4f9b | A | | 2-(pyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one | Human | 4828 | |
| PLK1 | PLK | Other | 4j53 | A | C | 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5h-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 4963 | |
| AURKA (AurA) | Aur | Other | 5osd | A | | adenosine-5'-diphosphate | Human | 8634 | |
| AURKA (AurA) | Aur | Other | 6cpg | D | | 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1h-benzimidazol-2-yl]-1h-pyrazol-4-yl}urea | Human | 10034 | |
| AURKA (AurA) | Aur | Other | 4j8m | A | | 1-[4-[[4-[(5-cyclopentyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl]amino]phenyl]-3-[3-(trifluoromethyl)phenyl]urea | Human | 2020 | |
| AAK1 | NAK | Other | 5l4q | A | B | ~{n}-[5-(4-cyanophenyl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide | Human | 6677 | |
| AURKA (AurA) | Aur | Other | 5obj | A | | adenosine-5'-triphosphate | Human | 8305 | |
| AURKA (AurA) | Aur | Other | 3o50 | A | | n-{3-methyl-4-[(3-pyrimidin-4-ylpyridin-2-yl)oxy]phenyl}-3-(trifluoromethyl)benzamide | Human | 1958 | |
| AURKA (AurA) | Aur | Other | 3uod | A | | 4-[(4-{[2-(trifluoromethyl)phenyl]amino}pyrimidin-2-yl)amino]benzoic acid | Human | 1980 | |
| PLK1 | PLK | Other | 2ou7 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 4973 | |
| PLK1 | PLK | Other | 4j52 | A | A | 4-{[(7r)-9-cyclopentyl-7-ethenyl-7-fluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5h-pyrimido[4,5-b][1,4]diazepin-2-yl]amino}-3-methoxy-n-(4-methylpiperazin-1-yl)benzamide | Human | 4955 | |
| PLK1 | PLK | Other | 5ta6 | A | A | 4-{[(6r)-7-cyano-5-cyclopentyl-6-ethyl-5,6-dihydroimidazo[1,5-f]pteridin-3-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 7465 | |
| ERN1 (IRE1) | IRE | Other | 6w3c | A | | - | Human | 13040 | |
| PLK1 | PLK | Other | 4a4o | A | | 1-methyl-2-(2-{[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one | Human | 4965 | |
| AURKA (AurA) | Aur | Other | 2w1g | A | | 2-{4-[(cyclopropylcarbamoyl)amino]-1h-pyrazol-3-yl}-6-(morpholin-4-ium-4-ylmethyl)-1h-3,1-benzimidazol-3-ium | Human | 1962 | |
| AURKA (AurA) | Aur | Other | 5orx | A | | adenosine-5'-diphosphate | Human | 8644 | |
| AURKA (AurA) | Aur | Other | 2x6e | A | | 6-bromo-7-{4-[(5-methylisoxazol-3-yl)methyl]piperazin-1-yl}-2-[4-(4-methylpiperazin-1-yl)phenyl]-1h-imidazo[4,5-b]pyridine | Human | 2079 | |
| AURKA (AurA) | Aur | Other | 7ayi | A | | 7-(2-phenylazanylpyrimidin-4-yl)-1,3,4,5-tetrahydro-1-benzazepin-2-one | Human | 13229 | |
| AURKA (AurA) | Aur | Other | 2c6e | B | | n-{5-[(7-{[(2s)-2-hydroxy-3-piperidin-1-ylpropyl]oxy}-6-methoxyquinazolin-4-yl)amino]pyrimidin-2-yl}benzamide | Human | 2046 | |
| PKMYT1 (MYT1) | WEE | Other | 8d6e | A | A | (1p)-2-amino-1-(3-hydroxy-2,6-dimethylphenyl)-5,6-dimethyl-1h-pyrrolo[2,3-b]pyridine-3-carboxamide | Human | 14295 | |
| AURKA (AurA) | Aur | Other | 3uoj | B | | 4-({4-[(2-cyanophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | Human | 1979 | |
| AURKA (AurA) | Aur | Other | 4c3p | D | | phosphomethylphosphonic acid adenylate ester | Human | 2030 | |
| TTK | TTK | Other | 3wzk | A | | n-cyclopropyl-4-{8-[(thiophen-2-ylmethyl)amino]imidazo[1,2-a]pyrazin-3-yl}benzamide | Human | 4703 | |
| WEE1 (Wee1) | WEE | Other | 5vda | A | | 1-{6-[(1s)-1-hydroxyethyl]pyridin-2-yl}-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-one | Human | 9779 | |
| TTK | TTK | Other | 7cil | A | B | 4-(cyclohexylamino)-2-[(1-methylpyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | 13555 | |
| TTK | TTK | Other | 5ap3 | A | | 9-cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8h-purin-8-one | Human | 6099 | |
| PLK3 | PLK | Other | 4b6l | A | | 4-[[(4r)-5-cyclopentyl-4-ethyl-3a,4-dihydro-3h-[1,2,4]triazolo[4,3-f]pteridin-7-yl]amino]-n-cyclopropyl-3-methoxy-benzamide | Human | 3797 | |
| ULK1 | ULK | Other | 4wnp | D | B | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1880 | |
| ULK1 | ULK | Other | 4wnp | B | A | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1872 | |
| ULK1 | ULK | Other | 9f32 | A | A | n-[4-(1h-indazol-5-yl)phenyl]propanamide | Human | 15545 | |
| ULK1 | ULK | Other | 6qas | B | B | n-{2-[(1s,4r)-6-{[4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,2,3,4-tetrahydro-1,4-epiminonaphthalen-9-yl]-2-oxoethyl}acetamide | Human | 10933 | |
| ULK1 | ULK | Other | 9se8 | A | A | ~{n}4-cyclopropyl-~{n}2-(1,2,3,4-tetrahydroisoquinolin-6-yl)-5-(trifluoromethyl)pyrimidine-2,4-diamine | Human | 15546 | |
| TTK | TTK | Other | 7cil | A | A | 4-(cyclohexylamino)-2-[(1-methylpyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | 13549 | |
| ULK1 | ULK | Other | 5ci7 | A | A | n-[3-({4-[(3-aminopropyl)amino]-5-iodopyrimidin-2-yl}amino)phenyl]pyrrolidine-1-carboxamide | Human | 5974 | |
| ULK1 | ULK | Other | 6qas | B | A | n-{2-[(1s,4r)-6-{[4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,2,3,4-tetrahydro-1,4-epiminonaphthalen-9-yl]-2-oxoethyl}acetamide | Human | 10932 | |
| ULK1 | ULK | Other | 6qas | A | B | n-{2-[(1s,4r)-6-{[4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,2,3,4-tetrahydro-1,4-epiminonaphthalen-9-yl]-2-oxoethyl}acetamide | Human | 10931 | |
| ULK1 | ULK | Other | 4wnp | C | B | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1873 | |
| ULK1 | ULK | Other | 6qas | A | A | n-{2-[(1s,4r)-6-{[4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,2,3,4-tetrahydro-1,4-epiminonaphthalen-9-yl]-2-oxoethyl}acetamide | Human | 10930 | |
| ULK1 | ULK | Other | 6mnh | A | B | n-[(2r)-3-methylbutan-2-yl]-1h-benzotriazole-6-carboxamide | Human | 10980 | |
| ULK1 | ULK | Other | 9se8 | A | B | ~{n}4-cyclopropyl-~{n}2-(1,2,3,4-tetrahydroisoquinolin-6-yl)-5-(trifluoromethyl)pyrimidine-2,4-diamine | Human | 15547 | |
| ULK2 | ULK | Other | 6yid | B | B | 2-({5-bromo-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}oxy)-n-methylbenzene-1-carboximidic acid | Human | 12387 | |
| TTK | TTK | Other | 4o6l | A | | n-[(1r)-1-(2-chlorophenyl)propyl]-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-1h-indazole-5-carboxamide | Human | 4730 | |
| ULK1 | ULK | Other | 4wnp | D | A | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1875 | |
| ULK2 | ULK | Other | 6qav | C | B | ~{n}-[3-[[5-cyclopropyl-2-[(2-methyl-3,4-dihydro-1~{h}-isoquinolin-6-yl)amino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide | Human | 11228 | |
| ULK2 | ULK | Other | 6qav | D | B | ~{n}-[3-[[5-cyclopropyl-2-[(2-methyl-3,4-dihydro-1~{h}-isoquinolin-6-yl)amino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide | Human | 11238 | |
| ERN1 (IRE1) | IRE | Other | 6xdd | A | | 4-[(trans-4-aminocyclohexyl)amino]-n-(6-chloro-3-{[(2,5-difluorophenyl)sulfonyl]amino}-2-fluorophenyl)thieno[3,2-d]pyrimidine-7-carboxamide | Human | 13529 | |
| EIF2AK1 (HRI) | PEK | Other | 9rhh | A | | - | Human | 15549 | |
| PLK4 | PLK | Other | 4jxf | A | | (1r,2s)-2-{3-[(e)-2-{4-[(dimethylamino)methyl]phenyl}ethenyl]-2h-indazol-6-yl}-5'-methoxyspiro[cyclopropane-1,3'-indol]-2'(1'h)-one | Human | 1816 | |
| PLK4 | PLK | Other | 3cok | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 1818 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5yva | A | | 3-(1h-tetrazol-5-yl)-10lambda~6~-thioxanthene-9,10,10-trione | Human | 10750 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6bqq | A | | 4-{[(7r)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 9063 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6ble | A | A | 1-{2-[5-(2-methoxyethoxy)-1h-benzimidazol-1-yl]quinolin-8-yl}piperidin-4-amine | Human | 8688 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6cmj | A | A | 2-(2-methylpropyl)-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9784 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5uyj | A | A | 2-cyclopentyl-4-(7-methoxyquinolin-4-yl)benzoic acid | Human | 7560 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6ble | A | B | 1-{2-[5-(2-methoxyethoxy)-1h-benzimidazol-1-yl]quinolin-8-yl}piperidin-4-amine | Human | 8689 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5yv8 | A | A | 1-amino-4-hydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid | Human | 10753 | |
| ERN1 (IRE1) | IRE | Other | 4yz9 | A | A | (5r)-2-(3,4-dichlorobenzyl)-n-(4-methylbenzyl)-2,7-diazaspiro[4.5]decane-7-carboxamide | Human | 6233 | |
| ERN1 (IRE1) | IRE | Other | 6w3a | A | B | ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]but-2-ynamide | Human | 13116 | |
| ERN1 (IRE1) | IRE | Other | 4yzc | B | A | staurosporine | Human | 6227 | |
| ERN1 (IRE1) | IRE | Other | 4yz9 | B | A | (5r)-2-(3,4-dichlorobenzyl)-n-(4-methylbenzyl)-2,7-diazaspiro[4.5]decane-7-carboxamide | Human | 6225 | |
| ERN1 (IRE1) | IRE | Other | 6hx1 | A | A | 6-chloranyl-~{n}-(cyclopropylmethyl)-3-(2~{h}-indazol-5-yl)imidazo[1,2-b]pyridazin-8-amine | Human | 10927 | |
| ULK1 | ULK | Other | 8sv9 | A | A | (4p)-4-[(2p)-2-(1,2,5,6-tetrahydropyridin-3-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n-(2,2,2-trifluoroethyl)thiophene-2-carboxamide | Human | 15222 | |
| ULK4 | ULK | Other | 6u5l | A | A | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 11890 | |
| ULK4 | ULK | Other | 6tsz | U | | phosphothiophosphoric acid-adenylate ester | Human | 11904 | |
| ERN1 (IRE1) | IRE | Other | 4z7h | B | | 2-methoxy-4-[6-(propan-2-ylamino)imidazo[1,2-b]pyridazin-3-yl]benzamide | Human | 1801 | |
| ERN1 (IRE1) | IRE | Other | 4u6r | A | | n-{4-[(3-{2-[(trans-4-aminocyclohexyl)amino]pyrimidin-4-yl}pyridin-2-yl)oxy]-3-methylnaphthalen-1-yl}-2-chlorobenzenesulfonamide | Human | 1802 | |
| AURKC (AurC) | Aur | Other | 6gr9 | A | A | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 11123 | |
| AURKA (AurA) | Aur | Other | 8sso | A | C | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 14863 | |
| AURKA (AurA) | Aur | Other | 8sso | A | B | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 14867 | |
| ULK2 | ULK | Other | 6qau | C | A | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 11229 | |
| ULK2 | ULK | Other | 6qav | B | B | ~{n}-[3-[[5-cyclopropyl-2-[(2-methyl-3,4-dihydro-1~{h}-isoquinolin-6-yl)amino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide | Human | 11237 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | C | B | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9715 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | B | B | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9713 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | C | A | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9711 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6ccf | B | | n-[2-oxo-3-((e)-phenyl{[4-(piperidin-1-ylmethyl)phenyl]imino}methyl)-2,6-dihydro-1h-indol-5-yl]ethanesulfonamide | Human | 9717 | |
| ERN1 (IRE1) | IRE | Other | 4yzd | A | A | adenosine-5'-diphosphate | Human | 6234 | |
| ERN1 (IRE1) | IRE | Other | 4yzd | C | A | adenosine-5'-diphosphate | Human | 6237 | |
| ERN1 (IRE1) | IRE | Other | 6w39 | B | A | ethyl ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]carbamate | Human | 13117 | |
| ERN1 (IRE1) | IRE | Other | 4yzd | A | B | adenosine-5'-diphosphate | Human | 6228 | |
| ERN1 (IRE1) | IRE | Other | 6xdf | B | B | - | Human | 13507 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 8tuc | A | B | (4m)-2-cyclopentyl-4-(7-ethoxyquinazolin-4-yl)benzoic acid | Human | 15004 | |
| ERN1 (IRE1) | IRE | Other | 4yz9 | C | A | (5r)-2-(3,4-dichlorobenzyl)-n-(4-methylbenzyl)-2,7-diazaspiro[4.5]decane-7-carboxamide | Human | 6223 | |
| PKMYT1 (MYT1) | WEE | Other | 8wjy | A | B | [6-azanyl-5-(2,6-dimethyl-3-oxidanyl-phenyl)-2,3-dimethyl-pyrrolo[2,3-b]pyrazin-7-yl]-(6,7-dihydro-4~{h}-pyrazolo[1,5-a]pyrazin-5-yl)methanone | Human | 15007 | |
| ERN1 (IRE1) | IRE | Other | 6w3b | A | | - | Human | 13039 | |
| AURKA (AurA) | Aur | Other | 4j8n | D | | - | Human | 1995 | |
| AURKA (AurA) | Aur | Other | 3uo6 | B | | 4-({4-[(2-chlorophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | Human | 1960 | |
| AURKA (AurA) | Aur | Other | 4byi | A | | (s)-n-((1-(6-chloro-2-(1,3-dimethyl-1h-pyrazol-4-yl)-3h-imidazo[4,5-b]pyridin-7-yl)pyrrolidin-3-yl)methyl)acetamide | Human | 1992 | |
| AURKA (AurA) | Aur | Other | 5aaf | A | | 3-((4-(6-chloro-2-(1,3-dimethyl-1h-pyrazol-4-yl)-3h-imidazo[4,5-b]pyridin-7-yl)-1h-pyrazol-1-yl)methyl)-n,n-dimethylbenzamide | Human | 6013 | |
| AURKA (AurA) | Aur | Other | 5l8l | A | A | adenosine-5'-diphosphate | Human | 6822 | |
| AURKA (AurA) | Aur | Other | 3r21 | A | B | n-(2-aminoethyl)-n-{5-[(1-cycloheptyl-1h-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide | Human | 2033 | |
| RNASEL (RNAseL) | Other-Unique | Other | 4oav | D | | phosphomethylphosphonic acid adenylate ester | Human | 466 | |
| AURKA (AurA) | Aur | Other | 5os4 | A | | adenosine-5'-diphosphate | Human | 8652 | |
| AURKA (AurA) | Aur | Other | 2wtv | B | B | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 2057 | |
| AURKA (AurA) | Aur | Other | 5g1x | A | A | adenosine-5'-diphosphate | Human | 7267 | |
| AURKA (AurA) | Aur | Other | 5orp | A | | adenosine-5'-diphosphate | Human | 8648 | |
| AURKA (AurA) | Aur | Other | 5g15 | A | B | phosphomethylphosphonic acid adenylate ester | Human | 9739 | |
| AURKA (AurA) | Aur | Other | 5os2 | A | B | adenosine-5'-diphosphate | Human | 8633 | |
| AURKA (AurA) | Aur | Other | 3k5u | A | | 2-[(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amino]ethanol | Human | 2031 | |
| AURKA (AurA) | Aur | Other | 5dpv | A | A | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 6808 | |
| ULK4 | ULK | Other | 6u5l | A | B | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 11889 | |
| AURKA (AurA) | Aur | Other | 6r4c | A | | adenosine-5'-diphosphate | Human | 11135 | |
| PBK | TOPK | Other | 5j0a | A | | - | Human | 7083 | |
| AURKC (AurC) | Aur | Other | 9esa | A | A | - | Human | 15567 | |
| AURKC (AurC) | Aur | Other | 6gr8 | A | A | 1-[(2~{r},3~{s})-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-3-methyl-6-oxidanylidene-5-[(2~{s})-1-oxidanylpropan-2-yl]-3,4-dihydro-2~{h}-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea | Human | 11122 | |
| AURKC (AurC) | Aur | Other | 9esa | A | B | - | Human | 15568 | |
| AURKC (AurC) | Aur | Other | 6gr9 | A | B | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 11124 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5yv8 | A | B | 1-amino-4-hydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid | Human | 10755 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5uy6 | A | | 2-cyclopentyl-4-(5-phenylfuro[2,3-b]pyridin-3-yl)benzoic acid | Human | 7982 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5yvb | A | | (3z)-5-chloro-3-[(1-methyl-1h-pyrazol-4-yl)methylidene]-1,3-dihydro-2h-indol-2-one | Human | 10751 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6bql | A | | 2-({5-chloro-2-[(2-methoxy-4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl}amino)-n-methylbenzamide | Human | 9061 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5yvc | A | | 3-{2,4-dimethyl-5-[(z)-(2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-1h-pyrrol-3-yl}propanoic acid | Human | 10754 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6brc | B | | 5-chloro-n~2~-{4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl}-n~4~-[2-(dimethylphosphoryl)phenyl]pyrimidine-2,4-diamine | Human | 9060 | |
| ERN1 (IRE1) | IRE | Other | 4yzd | B | A | adenosine-5'-diphosphate | Human | 6236 | |
| ERN1 (IRE1) | IRE | Other | 6urc | A | | 2-chloro-n-(6-methyl-5-{[3-(2-{[(3s)-piperidin-3-yl]amino}pyrimidin-4-yl)pyridin-2-yl]oxy}naphthalen-1-yl)benzene-1-sulfonamide | Human | 11799 | |
| ERN1 (IRE1) | IRE | Other | 4z7g | B | | - | Human | 1796 | |
| ERN1 (IRE1) | IRE | Other | 6w39 | A | B | ethyl ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]carbamate | Human | 13122 | |
| AURKA (AurA) | Aur | Other | 5dt0 | A | A | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 6806 | |
| AURKA (AurA) | Aur | Other | 3p9j | A | | 4-[(5-methyl-1h-pyrazol-3-yl)amino]-2-phenylphthalazin-1(2h)-one | Human | 2003 | |
| AURKA (AurA) | Aur | Other | 5dt4 | A | | adenosine-5'-triphosphate | Human | 6815 | |
| WNK3 (Wnk3) | WNK | Other | 5o1v | B | B | - | Human | 8150 | |
| WNK3 (Wnk3) | WNK | Other | 5o26 | B | A | phosphoaminophosphonic acid-adenylate ester | Human | 8162 | |
| ERN1 (IRE1) | IRE | Other | 6hv0 | A | | 6-chloranyl-3-(2~{h}-indazol-5-yl)-~{n}-propan-2-yl-imidazo[1,2-b]pyridazin-8-amine | Human | 10928 | |
| WNK3 (Wnk3) | WNK | Other | 5o26 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 8164 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5uyj | A | B | 2-cyclopentyl-4-(7-methoxyquinolin-4-yl)benzoic acid | Human | 7559 | |
| TBK1 | IKK | Other | 4iwo | A | | n-{3-[(5-cyclopropyl-2-{[3-(2-oxopyrrolidin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 614 | |
| AURKA (AurA) | Aur | Other | 6vpm | B | A | adenosine monophosphate | Human | 12660 | |
| PKMYT1 (MYT1) | WEE | Other | 5vd3 | A | | n-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(tetrahydro-2h-pyran-4-yloxy)quinazolin-4-amine | Human | 8343 | |
| PKMYT1 (MYT1) | WEE | Other | 5vd1 | A | A | n,1,4,4-tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 8337 | |
| PKMYT1 (MYT1) | WEE | Other | 3p1a | A | B | - | Human | 1217 | |
| PKMYT1 (MYT1) | WEE | Other | 5vcw | B | | (2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxyquinolin-6-yl}-4-(dimethylamino)but-2-enamide | Human | 8346 | |
| PKMYT1 (MYT1) | WEE | Other | 5vcy | A | A | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 8345 | |
| PKMYT1 (MYT1) | WEE | Other | 5vcy | A | B | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 8338 | |
| PKMYT1 (MYT1) | WEE | Other | 5vcz | A | B | 4-[(3,5-dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 8336 | |
| PKMYT1 (MYT1) | WEE | Other | 5vcx | A | | n-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(tetrahydro-2h-pyran-4-yloxy)quinazolin-4-amine | Human | 8341 | |
| PKMYT1 (MYT1) | WEE | Other | 8d6c | A | | (1p)-2-amino-6-bromo-1-(3-hydroxy-2,6-dimethylphenyl)-1h-pyrrolo[2,3-b]quinoxaline-3-carboxamide | Human | 14296 | |
| PKMYT1 (MYT1) | WEE | Other | 3p1a | A | A | - | Human | 1216 | |
| PKMYT1 (MYT1) | WEE | Other | 5vcv | A | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 8339 | |
| PKMYT1 (MYT1) | WEE | Other | 5vcw | A | | (2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxyquinolin-6-yl}-4-(dimethylamino)but-2-enamide | Human | 8335 | |
| NEK2 | NEK | Other | 2w5b | A | B | phosphothiophosphoric acid-adenylate ester | Human | 305 | |
| BUB1 | BUB | Other | 4qpm | A | | adenosine-5'-diphosphate | Human | 1843 | |
| BUB1 | BUB | Other | 5dmz | B | | adenosine-5'-diphosphate | Human | 6286 | |
| BUB1 | BUB | Other | 6f7b | A | A | 2-[3,5-bis(fluoranyl)-4-[[3-[5-methoxy-4-[(3-methoxypyridin-4-yl)amino]pyrimidin-2-yl]indazol-1-yl]methyl]phenoxy]ethanol | Human | 10808 | |
| BUB1 | BUB | Other | 4r8q | A | | adenosine-5'-diphosphate | Human | 1842 | |
| NEK2 | NEK | Other | 6sgh | A | A | 2-[4-[(6-ethenyl-9~{h}-purin-2-yl)amino]phenyl]ethanamide | Human | 12374 | |
| NEK2 | NEK | Other | 6sk9 | A | A | 3-[[6-(cyclohexylmethoxy)-7~{h}-purin-2-yl]amino]-~{n}-[3-(dimethylamino)propyl]benzenesulfonamide | Human | 12376 | |
| PLK1 | PLK | Other | 3fc2 | A | A | n-{trans-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}-4-{[(7r)-7-ethyl-5-methyl-8-(1-methylethyl)-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzamide | Human | 4964 | |
| PKMYT1 (MYT1) | WEE | Other | 5vd0 | A | | 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-one | Human | 8344 | |
| AAK1 | NAK | Other | 8gmd | A | | (5p)-3-({(8r)-5-[(4-aminopiperidin-1-yl)methyl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}amino)-5-[2-(propan-2-yl)-2h-tetrazol-5-yl]phenol | Human | 14844 | |
| AAK1 | NAK | Other | 8gmc | A | | 5-[(4-aminopiperidin-1-yl)methyl]-n-{3-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]phenyl}pyrrolo[2,1-f][1,2,4]triazin-4-amine | Human | 14843 | |
| NEK7 | NEK | Other | 2wqn | A | A | adenosine-5'-diphosphate | Human | 3855 | |
| NEK7 | NEK | Other | 6s76 | D | | - | Human | 12361 | |
| WEE1 (Wee1) | WEE | Other | 2z2w | A | | n-[4-(2-chlorophenyl)-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-c]carbazol-9-yl]formamide | Human | 203 | |
| WEE1 (Wee1) | WEE | Other | 5vd2 | A | | n-{2-[(1s,4r)-6-{[4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,2,3,4-tetrahydro-1,4-epiminonaphthalen-9-yl]-2-oxoethyl}acetamide | Human | 8330 | |
| WEE1 (Wee1) | WEE | Other | 5vc5 | A | B | 6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 8333 | |
| WEE1 (Wee1) | WEE | Other | 9r55 | A | | mips-54859 | Human | 15666 | |
| WEE1 (Wee1) | WEE | Other | 5vd5 | A | | 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(morpholin-4-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-one | Human | 9778 | |
| WEE1 (Wee1) | WEE | Other | 5v5y | A | | 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-one | Human | 8328 | |
| WEE1 (Wee1) | WEE | Other | 5vd8 | A | | 6-{[3-chloro-4-(4-methylpiperazin-1-yl)phenyl]amino}-1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-2-(prop-2-en-1-yl)-1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-one | Human | 9777 | |
| WEE1 (Wee1) | WEE | Other | 1x8b | A | | 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2h,6h)-dione | Human | 209 | |
| WEE1 (Wee1) | WEE | Other | 5vc3 | A | | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 8329 | |
| WEE1 (Wee1) | WEE | Other | 3bi6 | A | A | 4-(2-chlorophenyl)-9-hydroxy-6-methyl-1,3-dioxo-n-(2-pyrrolidin-1-ylethyl)pyrrolo[3,4-g]carbazole-8-carboxamide | Human | 213 | |
| WEE1 (Wee1) | WEE | Other | 5vc5 | A | A | 6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 8332 | |
| WEE1 (Wee1) | WEE | Other | 9d0r | A | | 7-methyl-2-{[1-(1-methylpiperidin-4-yl)-1h-pyrazol-4-yl]amino}-6-[(1r)-1-(thiophen-2-yl)ethyl]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | 15667 | |
| WEE1 (Wee1) | WEE | Other | 3cr0 | A | A | 4-(2-chlorophenyl)-8-(2-hydroxyethyl)-6-methylpyrrolo[3,4-e]indole-1,3(2h,6h)-dione | Human | 208 | |
| WEE1 (Wee1) | WEE | Other | 3cr0 | A | B | 4-(2-chlorophenyl)-8-(2-hydroxyethyl)-6-methylpyrrolo[3,4-e]indole-1,3(2h,6h)-dione | Human | 212 | |
| WEE1 (Wee1) | WEE | Other | 5vd7 | A | | 6-{[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]amino}-1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-2-(prop-2-en-1-yl)-1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-one | Human | 9782 | |
| WEE1 (Wee1) | WEE | Other | 9d0s | A | | (8p)-3-(2,6-dichlorophenyl)-1-methyl-8-[1-(1-methylpiperidin-4-yl)-1h-pyrazol-4-yl]-1,2,3,7-tetrahydro-4h-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-4-one | Human | 15668 | |
| WEE1 (Wee1) | WEE | Other | 5vd4 | A | | 6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1-{6-[(1s)-2,2,2-trifluoro-1-hydroxyethyl]pyridin-2-yl}-1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-one | Human | 9780 | |
| WEE1 (Wee1) | WEE | Other | 3biz | A | A | 4-(2-chlorophenyl)-8-[3-(dimethylamino)propoxy]-9-hydroxy-6-methylpyrrolo[3,4-c]carbazole-1,3(2h,6h)-dione | Human | 210 | |
| WEE1 (Wee1) | WEE | Other | 3biz | A | B | 4-(2-chlorophenyl)-8-[3-(dimethylamino)propoxy]-9-hydroxy-6-methylpyrrolo[3,4-c]carbazole-1,3(2h,6h)-dione | Human | 204 | |
| WEE1 (Wee1) | WEE | Other | 8bju | A | A | 2-(2-methoxyphenyl)-6-[[4-(4-methylpiperazin-1-yl)phenyl]amino]-1-[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]pyrazolo[3,4-d]pyrimidin-3-one | Human | 14755 | |
| WEE1 (Wee1) | WEE | Other | 3bi6 | A | B | 4-(2-chlorophenyl)-9-hydroxy-6-methyl-1,3-dioxo-n-(2-pyrrolidin-1-ylethyl)pyrrolo[3,4-g]carbazole-8-carboxamide | Human | 205 | |
| CDC7 | CDC7 | Other | 4f9a | C | | adenosine-5'-diphosphate | Human | 4826 | |
| CDC7 | CDC7 | Other | 4f9b | C | | 2-(pyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one | Human | 4827 | |
| WEE1 (Wee1) | WEE | Other | 3cqe | A | B | 8-bromo-4-(2-chlorophenyl)-n-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole-7-carboxamide | Human | 211 | |
| WEE1 (Wee1) | WEE | Other | 2in6 | A | | 3-(9-hydroxy-1,3-dioxo-4-phenyl-2,3-dihydropyrrolo[3,4-c]carbazol-6(1h)-yl)propanoic acid | Human | 207 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 8tuc | A | A | (4m)-2-cyclopentyl-4-(7-ethoxyquinazolin-4-yl)benzoic acid | Human | 15005 | |
| PLK1 | PLK | Other | 8x72 | A | | phosphoaminophosphonic acid-adenylate ester | Human | 15097 | |
| EIF2AK4 (GCN2) | PEK | Other | 6n3l | A | A | n-{6-[(1-methyl-2-{[4-(trifluoromethyl)phenyl]amino}-1h-benzimidazol-5-yl)oxy]pyrimidin-4-yl}cyclopropanecarboxamide | Human | 11691 | |
| EIF2AK4 (GCN2) | PEK | Other | 8t7t | A | A | - | Human | 15229 | |
| AURKA (AurA) | Aur | Other | 8c1m | A | | adenosine-5'-diphosphate | Human | 15137 | |
| AURKA (AurA) | Aur | Other | 8c1f | A | A | adenosine-5'-diphosphate | Human | 15140 | |
| AURKA (AurA) | Aur | Other | 8c14 | A | B | adenosine-5'-diphosphate | Human | 15150 | |
| TTK | TTK | Other | 5ap0 | A | | 9-cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8h-purin-8-one | Human | 6101 | |
| AURKA (AurA) | Aur | Other | 8c15 | A | B | adenosine-5'-diphosphate | Human | 15151 | |
| AURKA (AurA) | Aur | Other | 8c1d | A | A | adenosine-5'-diphosphate | Human | 15152 | |
| ULK2 | ULK | Other | 6yid | C | A | 2-({5-bromo-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}oxy)-n-methylbenzene-1-carboximidic acid | Human | 12384 | |
| TTK | TTK | Other | 5n93 | A | | 4-[[4-azanyl-6-(~{tert}-butylamino)-5-cyano-pyridin-2-yl]amino]benzamide | Human | 7976 | |
| TTK | TTK | Other | 5n84 | A | | ~{n}-cyclopropyl-4-[8-(2-methylpropylamino)imidazo[1,2-a]pyrazin-3-yl]benzamide | Human | 7973 | |
| TTK | TTK | Other | 5na0 | A | | ~{n}-[3,5-diethyl-1-[2-[2-(2-methoxyethoxy)ethoxy]ethyl]pyrazol-4-yl]-2-[[2-methoxy-4-[4-(2-methoxyethanoyl)piperazin-1-yl]phenyl]amino]-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide | Human | 7974 | |
| TTK | TTK | Other | 5ap6 | A | A | isopropyl 6-((4-(1,2-dimethyl-1h-imidazol-5-yl)phenyl)amino)-2-(1-methyl-1h-pyrazol-4-yl)-1h-pyrrolo[3,2-c]pyridine-1-carboxylate | Human | 6098 | |
| TTK | TTK | Other | 4jt3 | A | | 2-phenyl-n-[3-(3-sulfamoylphenyl)-2h-indazol-5-yl]acetamide | Human | 4727 | |
| TTK | TTK | Other | 5n9s | A | | (2~{r})-2-(4-fluorophenyl)-~{n}-[4-[2-[(2-methoxy-4-methylsulfonyl-phenyl)amino]-[1,2,4]triazolo[1,5-a]pyridin-6-yl]phenyl]propanamide | Human | 7979 | |
| CDC7 | CDC7 | Other | 6ya7 | A | B | adenosine-5'-diphosphate | Human | 13842 | |
| ERN1 (IRE1) | IRE | Other | 6xdf | B | A | - | Human | 13508 | |
| ERN1 (IRE1) | IRE | Other | 4yzd | B | B | adenosine-5'-diphosphate | Human | 6230 | |
| AURKA (AurA) | Aur | Other | 3uoj | A | | 4-({4-[(2-cyanophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | Human | 2042 | |
| TTK | TTK | Other | 4c4e | A | B | - | Human | 4726 | |
| TTK | TTK | Other | 4o6l | B | | n-[(1r)-1-(2-chlorophenyl)propyl]-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-1h-indazole-5-carboxamide | Human | 4720 | |
| TTK | TTK | Other | 5eh0 | A | | n2-(2-methoxy-4-(1-methyl-1h-pyrazol-4-yl)phenyl)-n8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine | Human | 6850 | |
| TTK | TTK | Other | 5ap5 | A | | tert-butyl 6-((2-chloro-4-(dimethylcarbamoyl)phenyl)amino)-2-(1-methyl-1h-pyrazol-4-yl)-1h-pyrrolo[3,2-c]pyridine-1-carboxylate | Human | 6104 | |
| TTK | TTK | Other | 5eho | A | | ~{n}8-cyclohexyl-~{n}2-[2-methoxy-4-(1-methylpyrazol-4-yl)phenyl]pyrido[3,4-d]pyrimidine-2,8-diamine | Human | 7257 | |
| IKBKB (IKKb) | IKK | Other | 4kik | B | B | k-252a | Human | 293 | |
| IKBKB (IKKb) | IKK | Other | 4e3c | B | | - | Human | 294 | |
| IKBKB (IKKb) | IKK | Other | 4kik | A | B | k-252a | Human | 288 | |
| EIF2AK3 (PEK) | PEK | Other | 4x7h | A | B | n-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]pyridin-2-yl}-1-methyl-3-oxo-2-phenyl-5-(pyridin-4-yl)-2,3-dihydro-1h-pyrazole-4-carboxamide | Human | 7240 | |
| EIF2AK3 (PEK) | PEK | Other | 4g34 | A | B | 1-[5-(4-aminothieno[3,2-c]pyridin-3-yl)-2,3-dihydro-1h-indol-1-yl]-2-phenylethanone | Human | 2670 | |
| EIF2AK3 (PEK) | PEK | Other | 4x7k | A | B | 4-{2-amino-3-[5-fluoro-2-(methylamino)quinazolin-6-yl]-4-methylbenzoyl}-1-methyl-2,5-diphenyl-1,2-dihydro-3h-pyrazol-3-one | Human | 7242 | |
| EIF2AK3 (PEK) | PEK | Other | 4x7o | A | B | 1-[5-(4-amino-2,7-dimethyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1h-indol-1-yl]-2-[3-fluoro-5-(trifluoromethyl)phenyl]ethanone | Human | 7244 | |
| EIF2AK3 (PEK) | PEK | Other | 8eqe | A | | (2r)-n-[(4m)-4-(4-amino-2,7-dimethyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-3-methylphenyl]-2-hydroxy-2-[3-(trifluoromethyl)phenyl]acetamide | Human | 14522 | |
| EIF2AK3 (PEK) | PEK | Other | 4x7n | A | B | 4-[2-amino-4-methyl-3-(2-methylquinolin-6-yl)benzoyl]-1-methyl-2,5-diphenyl-1,2-dihydro-3h-pyrazol-3-one | Human | 7241 | |
| EIF2AK3 (PEK) | PEK | Other | 4m7i | A | | 1-[5-(4-amino-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-1h-indol-1-yl]-2-(6-methylpyridin-2-yl)ethanone | Human | 2673 | |
| ULK1 | ULK | Other | 4wnp | C | A | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1877 | |
| GAK | NAK | Other | 4o38 | A | B | - | Human | 335 | |
| EIF2AK2 (PKR) | PEK | Other | 3uiu | A | | - | Human | 917 | |
| AURKA (AurA) | Aur | Other | 8pr7 | A | | adenosine-5'-diphosphate | Human | 15292 | |
| WNK3 (Wnk3) | WNK | Other | 5o21 | B | | - | Human | 8158 | |
| WNK3 (Wnk3) | WNK | Other | 5o26 | B | B | phosphoaminophosphonic acid-adenylate ester | Human | 8156 | |
| WNK3 (Wnk3) | WNK | Other | 5o2b | B | B | 1-cyclopentyl-3-(1h-pyrrolo[2,3-b]pyridin-5-yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine | Human | 8161 | |
| GAK | NAK | Other | 4c58 | A | B | 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2h,6h)-dione | Human | 333 | |
| TBK1 | IKK | Other | 6rst | A | | 1-[4-[(1~{r})-1-[2-[[5-[1-(cyclopropylmethyl)pyrazol-4-yl]-1~{h}-benzimidazol-2-yl]amino]pyridin-4-yl]ethyl]piperazin-1-yl]-3,3,3-tris(fluoranyl)propan-1-one | Human | 11902 | |
| PKMYT1 (MYT1) | WEE | Other | 8d6d | A | | (1p)-2-amino-5-bromo-1-(3-hydroxy-2,6-dimethylphenyl)-1h-pyrrolo[2,3-b]quinoxaline-3-carboxamide | Human | 14294 | |
| TBK1 | IKK | Other | 4eut | B | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 618 | |
| TBK1 | IKK | Other | 4iwp | A | | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 612 | |
| TBK1 | IKK | Other | 6o8b | A | | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 11053 | |
| AURKA (AurA) | Aur | Other | 5zan | A | | 7-(4-methylpiperazin-1-yl)-n-(5-methyl-1h-pyrazol-3-yl)-2-[(e)-2-phenylethenyl]quinazolin-4-amine | Human | 10898 | |
| AURKA (AurA) | Aur | Other | 3qbn | A | | 5-chloro-n~4~-cyclopropyl-n~2~-[4-(2-methoxyethoxy)phenyl]pyrimidine-2,4-diamine | Human | 2032 | |
| AURKA (AurA) | Aur | Other | 8c1f | A | B | adenosine-5'-diphosphate | Human | 15149 | |
| AURKA (AurA) | Aur | Other | 4ceg | A | | adenosine-5'-diphosphate | Human | 2073 | |
| AURKA (AurA) | Aur | Other | 4c3r | A | | phosphomethylphosphonic acid adenylate ester | Human | 2058 | |
| AURKA (AurA) | Aur | Other | 8c15 | A | A | adenosine-5'-diphosphate | Human | 15141 | |
| AURKA (AurA) | Aur | Other | 1mq4 | A | | adenosine-5'-diphosphate | Human | 1977 | |
| AURKA (AurA) | Aur | Other | 4jai | A | | n-{4-[(6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridin-1-yl)amino]phenyl}benzamide | Human | 1999 | |
| AURKA (AurA) | Aur | Other | 5os2 | A | A | adenosine-5'-diphosphate | Human | 8635 | |
| ERN1 (IRE1) | IRE | Other | 4yz9 | C | B | (5r)-2-(3,4-dichlorobenzyl)-n-(4-methylbenzyl)-2,7-diazaspiro[4.5]decane-7-carboxamide | Human | 6222 | |
| EIF2AK2 (PKR) | PEK | Other | 9yuf | A | | dabrafenib | Human | 15962 | |
| TBK1 | IKK | Other | 6bod | A | | ethyl 2-amino-5-oxo-7-(propan-2-yl)-5h-[1]benzopyrano[2,3-b]pyridine-3-carboxylate | Human | 10370 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | A | B | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9714 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | B | A | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9709 | |
| WNK1 (Wnk1) | WNK | Other | 5we8 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 8324 | |
| WNK1 (Wnk1) | WNK | Other | 5we8 | B | B | phosphoaminophosphonic acid-adenylate ester | Human | 8320 | |
| BMP2K (BIKE) | NAK | Other | 5i3o | B | | n-(6-{3-[(dimethylsulfamoyl)amino]phenyl}-1h-indazol-3-yl)cyclopropanecarboxamide | Human | 6434 | |
| BMP2K (BIKE) | NAK | Other | 5ikw | A | | n-(6-{3-[(cyclopropylsulfonyl)amino]phenyl}-1h-indazol-3-yl)cyclopropanecarboxamide | Human | 6709 | |
| BMP2K (BIKE) | NAK | Other | 5i3o | A | | n-(6-{3-[(dimethylsulfamoyl)amino]phenyl}-1h-indazol-3-yl)cyclopropanecarboxamide | Human | 6437 | |
| BMP2K (BIKE) | NAK | Other | 4w9x | A | | baricitinib | Human | 3273 | |
| NEK2 | NEK | Other | 2w5b | A | A | phosphothiophosphoric acid-adenylate ester | Human | 320 | |
| NEK2 | NEK | Other | 6sgd | A | B | 4-[(6-ethenyl-7~{h}-purin-2-yl)amino]benzenesulfonamide | Human | 12375 | |
| NEK2 | NEK | Other | 2xnp | A | B | 4-{5-[(1-methylpiperidin-4-yl)oxy]-1h-benzimidazol-1-yl}-2-{(1r)-1-[2-(trifluoromethyl)phenyl]ethoxy}benzamide | Human | 322 | |
| NEK2 | NEK | Other | 2xkf | A | B | 1-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]piperidine-4-carboxylic acid | Human | 311 | |
| NEK2 | NEK | Other | 2xkf | A | A | 1-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]piperidine-4-carboxylic acid | Human | 315 | |
| NEK2 | NEK | Other | 5m53 | A | A | 3-[[6-(cyclohexylmethoxy)-7~{h}-purin-2-yl]amino]-~{n},~{n}-dimethyl-benzamide | Human | 7159 | |
| NEK7 | NEK | Other | 6s76 | A | | - | Human | 12351 | |
| NEK7 | NEK | Other | 6s76 | C | | - | Human | 12352 | |
| ULK2 | ULK | Other | 6qat | B | | n-{(3z)-2-oxo-3-[phenyl({4-[(piperidin-1-yl)methyl]phenyl}amino)methylidene]-2,3-dihydro-1h-indol-5-yl}ethanesulfonamide | Human | 11226 | |
| ULK2 | ULK | Other | 6qav | A | B | ~{n}-[3-[[5-cyclopropyl-2-[(2-methyl-3,4-dihydro-1~{h}-isoquinolin-6-yl)amino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide | Human | 11239 | |
| ULK2 | ULK | Other | 6qav | D | A | ~{n}-[3-[[5-cyclopropyl-2-[(2-methyl-3,4-dihydro-1~{h}-isoquinolin-6-yl)amino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide | Human | 11234 | |
| TTK | TTK | Other | 7chm | A | | 4-(cyclohexylamino)-2-[(2-methoxy-4-morpholin-4-ylcarbonyl-phenyl)amino]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | 13550 | |
| TTK | TTK | Other | 5n87 | A | | ~{n}-(2,6-diethylphenyl)-2-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide | Human | 7977 | |
| TTK | TTK | Other | 4c4e | A | A | n-(3,4-dimethoxyphenyl)-2-(1h-pyrazol-4-yl)-1h-pyrrolo[3,2-c]pyridin-6-amine | Human | 4708 | |
| TTK | TTK | Other | 3hmo | A | | staurosporine | Human | 4707 | |
| TTK | TTK | Other | 4c4g | A | | tert-butyl 6-((2-chloro-4-(dimethylcarbamoyl)phenyl)amino)-2-(1-methyl-1h-pyrazol-4-yl)-1h-pyrrolo[3,2-c]pyridine-1-carboxylate | Human | 4697 | |
| TTK | TTK | Other | 6tnc | A | | n-cyclopropyl-4-{8-[(thiophen-2-ylmethyl)amino]imidazo[1,2-a]pyrazin-3-yl}benzamide | Human | 12270 | |
| TTK | TTK | Other | 5ap2 | A | | isopropyl 6-((4-(1,2-dimethyl-1h-imidazol-5-yl)phenyl)amino)-2-(1-methyl-1h-pyrazol-4-yl)-1h-pyrrolo[3,2-c]pyridine-1-carboxylate | Human | 6105 | |
| PLK2 | PLK | Other | 4i6b | A | B | (7r)-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydropteridin-6(5h)-one | Human | 5562 | |
| PLK2 | PLK | Other | 4i6h | A | B | (7r)-8-cyclopentyl-7-ethyl-5-methyl-2-[2-(1,3-thiazol-4-yl)-1h-imidazol-1-yl]-7,8-dihydropteridin-6(5h)-one | Human | 5561 | |
| PLK2 | PLK | Other | 4i6b | A | A | (7r)-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydropteridin-6(5h)-one | Human | 5565 | |
| PLK2 | PLK | Other | 4i6f | A | B | (7r)-8-cyclopentyl-7-ethyl-5-methyl-2-(2-phenyl-1h-imidazol-1-yl)-7,8-dihydropteridin-6(5h)-one | Human | 5563 | |
| RNASEL (RNAseL) | Other-Unique | Other | 4oau | C | | adenosine-5'-diphosphate | Human | 468 | |
| RNASEL (RNAseL) | Other-Unique | Other | 4oav | B | | phosphomethylphosphonic acid adenylate ester | Human | 467 | |
| EIF2AK2 (PKR) | PEK | Other | 2a1a | B | | - | Human | 919 | |
| EIF2AK2 (PKR) | PEK | Other | 2a19 | C | | phosphoaminophosphonic acid-adenylate ester | Human | 918 | |
| EIF2AK2 (PKR) | PEK | Other | 6d3k | C | | adenosine-5'-diphosphate | Human | 11387 | |
| HASPIN (Haspin) | Haspin | Other | 9flc | A | A | 5-(1-methylpyrazol-3-yl)-3-pyridin-4-yl-thieno[3,2-b]pyridine | Human | 16112 | |
| HASPIN (Haspin) | Haspin | Other | 6g37 | A | A | 5-fluorotubercidin | Human | 9840 | |
| HASPIN (Haspin) | Haspin | Other | 9b2t | K | | - | Human | 16113 | |
| HASPIN (Haspin) | Haspin | Other | 7avq | A | A | (2~{r})-2-[[3-(2~{h}-indazol-5-yl)imidazo[1,2-b]pyridazin-6-yl]amino]butan-1-ol | Human | 13176 | |
| HASPIN (Haspin) | Haspin | Other | 6z5e | A | B | 11-cyclopropyl-14-(2-hydroxyethyl)-8,11,14,18,19,22-hexazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2(23),3,5,15(22),16,19-heptaen-7-one | Human | 12329 | |
| WNK3 (Wnk3) | WNK | Other | 5o26 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 8149 | |
| WNK3 (Wnk3) | WNK | Other | 5o23 | A | B | - | Human | 8155 | |
| WNK3 (Wnk3) | WNK | Other | 5o1v | B | A | - | Human | 8152 | |
| WNK3 (Wnk3) | WNK | Other | 5o2b | A | A | 1-cyclopentyl-3-(1h-pyrrolo[2,3-b]pyridin-5-yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine | Human | 8163 | |
| WNK3 (Wnk3) | WNK | Other | 8edh | A | | ethyl 1-(5,7-dimethoxy-4-methylquinolin-2-yl)piperidine-4-carboxylate | Human | 14631 | |
| WNK3 (Wnk3) | WNK | Other | 5o1v | A | B | - | Human | 8165 | |
| WNK3 (Wnk3) | WNK | Other | 5o21 | A | | - | Human | 8160 | |
| WNK3 (Wnk3) | WNK | Other | 5o23 | B | A | - | Human | 8159 | |
| WNK3 (Wnk3) | WNK | Other | 5o2b | A | B | 1-cyclopentyl-3-(1h-pyrrolo[2,3-b]pyridin-5-yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine | Human | 8153 | |
| WNK3 (Wnk3) | WNK | Other | 5o2c | A | | - | Human | 8148 | |
| PIK3R4 | VPS15 | Other | 9tw2 | B | | - | Human | 15421 | |
| PIK3R4 | VPS15 | Other | 9rx4 | B | | - | Human | 15422 | |
| CDC7 | CDC7 | Other | 6ya6 | A | B | 8-chloro-2-[(2s)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3h)-one | Human | 13841 | |
| CDC7 | CDC7 | Other | 6ya8 | A | B | adenosine-5'-diphosphate | Human | 13843 | |
| CDC7 | CDC7 | Other | 4f9a | A | | adenosine-5'-diphosphate | Human | 4825 | |
| CDC7 | CDC7 | Other | 6ya6 | A | A | 8-chloro-2-[(2s)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3h)-one | Human | 13844 | |
| GAK | NAK | Other | 4y8d | B | A | 2-methoxy-4-[3-(morpholin-4-yl)[1,2]thiazolo[4,3-b]pyridin-6-yl]aniline | Human | 347 | |
| GAK | NAK | Other | 4o38 | A | A | - | Human | 345 | |
| GAK | NAK | Other | 5y80 | A | B | gefitinib | Human | 10330 | |
| GAK | NAK | Other | 4c58 | A | A | 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2h,6h)-dione | Human | 336 | |
| GAK | NAK | Other | 4o38 | B | B | - | Human | 343 | |
| GAK | NAK | Other | 4y8d | A | B | 2-methoxy-4-[3-(morpholin-4-yl)[1,2]thiazolo[4,3-b]pyridin-6-yl]aniline | Human | 339 | |
| PBK | TOPK | Other | 5j0a | B | | - | Human | 7084 | |
| ERN1 (IRE1) | IRE | Other | 7bmk | A | A | 2,2,2-tris(fluoranyl)-~{n}-[4-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxynaphthalen-1-yl]ethanesulfonamide | Human | 13911 | |
| ERN1 (IRE1) | IRE | Other | 6w3c | C | | - | Human | 13036 | |
| ERN1 (IRE1) | IRE | Other | 4yzc | A | B | staurosporine | Human | 6232 | |
| ERN1 (IRE1) | IRE | Other | 4yz9 | A | B | (5r)-2-(3,4-dichlorobenzyl)-n-(4-methylbenzyl)-2,7-diazaspiro[4.5]decane-7-carboxamide | Human | 6224 | |
| ERN1 (IRE1) | IRE | Other | 5hgi | A | | - | Human | 6669 | |
| ERN1 (IRE1) | IRE | Other | 7bmk | A | B | 2,2,2-tris(fluoranyl)-~{n}-[4-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxynaphthalen-1-yl]ethanesulfonamide | Human | 13912 | |
| PLK1 | PLK | Other | 8bjt | A | | 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-one | Human | 14712 | |
| PLK1 | PLK | Other | 5ta8 | A | A | 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5h-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 7464 | |
| PLK1 | PLK | Other | 2v5q | A | B | - | Human | 4960 | |
| PLK1 | PLK | Other | 2v5q | B | A | - | Human | 4959 | |
| PLK1 | PLK | Other | 4a4l | A | | 1-methyl-5-(2-{[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)-1h-pyrrole-3-carboxamide | Human | 4971 | |
| PLK1 | PLK | Other | 9d0p | A | | 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-one | Human | 15472 | |
| PLK1 | PLK | Other | 4j53 | A | B | 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5h-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 4972 | |
| CHUK (IKKa) | IKK | Other | 5ebz | J | | 2-azanyl-5-phenyl-3-(4-sulfamoylphenyl)benzamide | Human | 7148 | |
| CHUK (IKKa) | IKK | Other | 5ebz | H | | 2-azanyl-5-phenyl-3-(4-sulfamoylphenyl)benzamide | Human | 7155 | |
| CHUK (IKKa) | IKK | Other | 5tqy | B | | - | Human | 7197 | |
| TBK1 | IKK | Other | 4euu | A | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 611 | |
| TBK1 | IKK | Other | 6nt9 | B | | - | Human | 10941 | |
| TBK1 | IKK | Other | 4im2 | A | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 620 | |
| TBK1 | IKK | Other | 4euu | B | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 616 | |
| TBK1 | IKK | Other | 6rsu | A | | 3,3,3-tris(fluoranyl)-1-[4-[(1~{r})-1-[2-[[(2~{s})-5-(5-propan-2-yloxypyrimidin-4-yl)-2,3-dihydro-1~{h}-benzimidazol-2-yl]amino]pyridin-4-yl]ethyl]piperazin-1-yl]propan-1-one | Human | 12126 | |
| TBK1 | IKK | Other | 4im2 | A | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 613 | |
| TBK1 | IKK | Other | 6rsr | A | | ~{n}-(cyclopropen-1-ylmethyl)-2-[[4-[[4-[3,3,3-tris(fluoranyl)propanoyl]piperazin-1-yl]methyl]pyridin-2-yl]amino]-1~{h}-benzimidazole-5-carboxamide | Human | 11903 | |
| AURKA (AurA) | Aur | Other | 5ors | A | | adenosine-5'-diphosphate | Human | 8646 | |
| AURKA (AurA) | Aur | Other | 2c6d | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 1981 | |
| AURKA (AurA) | Aur | Other | 1ol5 | A | | adenosine-5'-diphosphate | Human | 2080 | |
| AURKA (AurA) | Aur | Other | 4jbq | A | | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 1957 | |
| AURKA (AurA) | Aur | Other | 4zs0 | A | | 5-hydroxy-1'h-1,2'-bibenzimidazol-2(3h)-one | Human | 6801 | |
| AURKA (AurA) | Aur | Other | 2wtw | A | | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 1956 | |
| AURKA (AurA) | Aur | Other | 4jbo | A | | 1-(4-{2-[(6-{4-[2-(dimethylamino)ethoxy]phenyl}furo[2,3-d]pyrimidin-4-yl)amino]ethyl}phenyl)-3-phenylurea | Human | 2072 | |
| AURKA (AurA) | Aur | Other | 1ol7 | A | | adenosine-5'-diphosphate | Human | 2014 | |
| AURKA (AurA) | Aur | Other | 3lau | A | | n-[6-(4-hydroxyphenyl)-1h-indazol-3-yl]butanamide | Human | 1971 | |
| AURKA (AurA) | Aur | Other | 5dr6 | A | B | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 6805 | |
| AURKA (AurA) | Aur | Other | 4jbp | A | | 1-(4-{2-[(6-{4-[2-(4-hydroxypiperidin-1-yl)ethoxy]phenyl}furo[2,3-d]pyrimidin-4-yl)amino]ethyl}phenyl)-3-phenylurea | Human | 2041 | |
| AURKA (AurA) | Aur | Other | 4o0s | A | | adenosine | Human | 2039 | |
| AURKA (AurA) | Aur | Other | 5lxm | A | A | adenosine-5'-diphosphate | Human | 7142 | |
| AURKA (AurA) | Aur | Other | 6c2r | A | A | (2r,4r)-1-[(3-chloro-2-fluorophenyl)methyl]-4-({3-fluoro-6-[(5-methyl-1h-pyrazol-3-yl)amino]pyridin-2-yl}methyl)-2-methylpiperidine-4-carboxylic acid | Human | 10864 | |
| AURKA (AurA) | Aur | Other | 6vpj | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 12657 | |
| AURKA (AurA) | Aur | Other | 8sso | A | A | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 14866 | |
| AURKA (AurA) | Aur | Other | 5os0 | A | | adenosine-5'-diphosphate | Human | 8632 | |
| AURKA (AurA) | Aur | Other | 8jf4 | A | | 2-[4-[4-[bis(oxidanylidene)-$l^5-sulfanyl]oxyphenyl]carbonylpiperazin-1-yl]-6-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]-n-prop-2-ynyl-pyrimidine-4-carboxamide | Human | 15217 | |
| AURKA (AurA) | Aur | Other | 5os6 | A | | adenosine-5'-diphosphate | Human | 8651 | |
| AURKA (AurA) | Aur | Other | 6hjj | A | B | ~{n}-[4-(4-azanyl-1-propan-2-yl-pyrazolo[3,4-d]pyrimidin-3-yl)-3-methyl-phenyl]-4-[4-fluoranyl-3-(trifluoromethyl)phenyl]-4-oxidanylidene-butanamide | Human | 10412 | |
| AURKA (AurA) | Aur | Other | 2xng | A | B | n-(3-{3-chloro-8-[(4-morpholin-4-ylphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzyl)methanesulfonamide | Human | 2083 | |
| AURKA (AurA) | Aur | Other | 5dn3 | A | A | adenosine-5'-triphosphate | Human | 6802 | |
| AURKA (AurA) | Aur | Other | 2w1f | A | | n-[3-(1h-benzimidazol-2-yl)-1h-pyrazol-4-yl]benzamide | Human | 2055 | |
| AURKA (AurA) | Aur | Other | 4byj | A | | (s)-n-(1-(6-chloro-2-(1,3-dimethyl-1h-pyrazol-4-yl)-3h-imidazo[4,5-b]pyridin-7-yl)pyrrolidin-3-yl)acetamide | Human | 1969 | |
| AURKA (AurA) | Aur | Other | 5l8k | A | A | adenosine-5'-diphosphate | Human | 6819 | |
| AURKA (AurA) | Aur | Other | 3o51 | A | | n-[4-({3-[5-fluoro-2-(methylideneamino)pyrimidin-4-yl]pyridin-2-yl}oxy)phenyl]-2-(phenylamino)benzamide | Human | 1974 | |
| AURKA (AurA) | Aur | Other | 5g15 | A | A | phosphomethylphosphonic acid adenylate ester | Human | 9737 | |
| AURKA (AurA) | Aur | Other | 3uol | A | | n~4~-(2-chlorophenyl)-n~2~-[4-(1h-tetrazol-5-yl)phenyl]pyrimidine-2,4-diamine | Human | 2004 | |
| AURKA (AurA) | Aur | Other | 5os1 | A | A | adenosine-5'-diphosphate | Human | 8628 | |
| AURKA (AurA) | Aur | Other | 3h10 | D | | 9-chloro-7-(2,6-difluorophenyl)-n-{4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-5h-pyrimido[5,4-d][2]benzazepin-2-amine | Human | 2059 | |
| AURKA (AurA) | Aur | Other | 6r4d | A | | adenosine-5'-diphosphate | Human | 11132 | |
| AURKA (AurA) | Aur | Other | 4dhf | A | | 7-cyclopentyl-2-({1-methyl-5-[(4-methylpiperazin-1-yl)carbonyl]-1h-pyrrol-3-yl}amino)-7h-pyrrolo[2,3-d]pyrimidine-6-carboxamide | Human | 1964 | |
| AURKA (AurA) | Aur | Other | 5ort | A | | adenosine-5'-diphosphate | Human | 8638 | |
| AURKA (AurA) | Aur | Other | 3h0z | B | | 4-{[2-({4-[2-(4-acetylpiperazin-1-yl)-2-oxoethyl]phenyl}amino)-5-fluoropyrimidin-4-yl]amino}-n-(2-chlorophenyl)benzamide | Human | 1986 | |
| AURKA (AurA) | Aur | Other | 6vpg | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 12659 | |
| AURKA (AurA) | Aur | Other | 2bmc | E | | (3e)-n-(2,6-diethylphenyl)-3-{[4-(4-methylpiperazin-1-yl)benzoyl]imino}pyrrolo[3,4-c]pyrazole-5(3h)-carboxamide | Human | 2069 | |
| AURKA (AurA) | Aur | Other | 2j50 | B | | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 2050 | |
| AURKA (AurA) | Aur | Other | 4b0g | A | B | 6-bromo-2-(1-methyl-1h-imidazol-5-yl)-7-{4-[(5-methyl-1,2-oxazol-3-yl)methyl]piperazin-1-yl}-1h-imidazo[4,5-b]pyridine | Human | 2070 | |
| AURKA (AurA) | Aur | Other | 4prj | A | | n-[1-(3-cyanobenzyl)-1h-pyrazol-4-yl]-6-(1h-pyrazol-4-yl)-1h-indazole-3-carboxamide | Human | 2023 | |
| AURKA (AurA) | Aur | Other | 5oro | A | | adenosine-5'-diphosphate | Human | 8641 | |
| AURKA (AurA) | Aur | Other | 3h10 | B | | 9-chloro-7-(2,6-difluorophenyl)-n-{4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-5h-pyrimido[5,4-d][2]benzazepin-2-amine | Human | 1988 | |
| AURKA (AurA) | Aur | Other | 5orn | A | | adenosine-5'-diphosphate | Human | 8649 | |
| AURKA (AurA) | Aur | Other | 7ztl | A | A | adenosine-5'-diphosphate | Human | 14582 | |
| AURKA (AurA) | Aur | Other | 5g1x | A | B | adenosine-5'-diphosphate | Human | 7266 | |
| AURKA (AurA) | Aur | Other | 5l8j | A | A | adenosine-5'-diphosphate | Human | 6820 | |
| AURKA (AurA) | Aur | Other | 2wtv | D | B | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 2076 | |
| AURKA (AurA) | Aur | Other | 4ztr | A | | 6-({4-[(z)-{(2z)-2-[(4-ethylphenyl)imino]-3-methyl-4-oxo-1,3-thiazolidin-5-ylidene}methyl]pyridin-2-yl}amino)pyridine-3-carboxylic acid | Human | 6817 | |
| AURKA (AurA) | Aur | Other | 5orl | A | | adenosine-5'-diphosphate | Human | 8642 | |
| AURKA (AurA) | Aur | Other | 3coh | B | | 8-ethyl-3,10,10-trimethyl-4,5,6,8,10,12-hexahydropyrazolo[4',3':6,7]cyclohepta[1,2-b]pyrrolo[2,3-f]indol-9(1h)-one | Human | 2024 | |
| AURKA (AurA) | Aur | Other | 6r4a | A | | adenosine-5'-diphosphate | Human | 11134 | |
| AURKA (AurA) | Aur | Other | 9s14 | B | | adenosine-5'-diphosphate | Human | 15493 | |
| AURKA (AurA) | Aur | Other | 3uo4 | A | | 4-{[4-(biphenyl-2-ylamino)pyrimidin-2-yl]amino}benzoic acid | Human | 1976 | |
| AURKA (AurA) | Aur | Other | 6cpe | A | B | - | Human | 10035 | |
| AURKA (AurA) | Aur | Other | 3uoh | B | | 4-({4-[(2-bromophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | Human | 2000 | |
| AURKA (AurA) | Aur | Other | 2np8 | A | | n-{3-[(4-{[3-(trifluoromethyl)phenyl]amino}pyrimidin-2-yl)amino]phenyl}cyclopropanecarboxamide | Human | 2075 | |
| AURKA (AurA) | Aur | Other | 2wtv | C | A | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 2017 | |
| AURKA (AurA) | Aur | Other | 3h10 | A | | 9-chloro-7-(2,6-difluorophenyl)-n-{4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-5h-pyrimido[5,4-d][2]benzazepin-2-amine | Human | 2009 | |
| AURKA (AurA) | Aur | Other | 3uok | B | | 4-({4-[(2-chlorophenyl)amino]-5-fluoropyrimidin-2-yl}amino)benzoic acid | Human | 2047 | |
| AURKA (AurA) | Aur | Other | 6c2r | A | B | (2r,4r)-1-[(3-chloro-2-fluorophenyl)methyl]-4-({3-fluoro-6-[(5-methyl-1h-pyrazol-3-yl)amino]pyridin-2-yl}methyl)-2-methylpiperidine-4-carboxylic acid | Human | 10865 | |
| AURKA (AurA) | Aur | Other | 2xru | A | | 3-({[4-(4-methylpiperazin-1-yl)phenyl]carbonyl}amino)-n-[(1r)-1-phenylpropyl]-1h-thieno[3,2-c]pyrazole-5-carboxamide | Human | 1954 | |
| AURKA (AurA) | Aur | Other | 9guc | A | B | adenosine-5'-diphosphate | Human | 15495 | |
| AURKA (AurA) | Aur | Other | 3ha6 | A | | n~2~-(3,4-dimethoxyphenyl)-n~4~-[2-(2-fluorophenyl)ethyl]-n~6~-quinolin-6-yl-1,3,5-triazine-2,4,6-triamine | Human | 2048 | |
| AURKA (AurA) | Aur | Other | 6gra | A | | 1-[(2~{r},3~{s})-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-3-methyl-6-oxidanylidene-5-[(2~{s})-1-oxidanylpropan-2-yl]-3,4-dihydro-2~{h}-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea | Human | 11130 | |
| AURKA (AurA) | Aur | Other | 6r4b | A | B | adenosine-5'-diphosphate | Human | 11133 | |
| AURKA (AurA) | Aur | Other | 5dt3 | A | | adenosine-5'-triphosphate | Human | 6816 | |
| AURKA (AurA) | Aur | Other | 7fic | A | B | 6-[(5-cyclopropyl-1~{h}-pyrazol-3-yl)amino]-2-[4-[(3-methyl-4-oxidanyl-phenyl)methyl]piperazin-1-yl]-~{n}-prop-2-ynyl-pyrimidine-4-carboxamide | Human | 14233 | |
| AURKA (AurA) | Aur | Other | 6cpf | A | | phosphomethylphosphonic acid adenylate ester | Human | 10033 | |
| AURKA (AurA) | Aur | Other | 2wqe | A | | adenosine-5'-diphosphate | Human | 2071 | |
| AURKA (AurA) | Aur | Other | 8c1i | A | A | adenosine-5'-diphosphate | Human | 15144 | |
| AURKA (AurA) | Aur | Other | 5aag | A | | [3-[[4-[6-chloranyl-2-(1,3-dimethylpyrazol-4-yl)-3h-imidazo[4,5-b]pyridin-7-yl]pyrazol-1-yl]methyl]phenyl]-(4-methylpiperazin-1-yl)methanone | Human | 6010 | |
| AURKA (AurA) | Aur | Other | 6r49 | A | | adenosine-5'-diphosphate | Human | 11131 | |
| AURKA (AurA) | Aur | Other | 6vpm | B | B | adenosine monophosphate | Human | 12663 | |
| AURKA (AurA) | Aur | Other | 2bmc | B | | (3e)-n-(2,6-diethylphenyl)-3-{[4-(4-methylpiperazin-1-yl)benzoyl]imino}pyrrolo[3,4-c]pyrazole-5(3h)-carboxamide | Human | 2008 | |
| AURKA (AurA) | Aur | Other | 3efw | A | | 1-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea | Human | 2010 | |
| AURKA (AurA) | Aur | Other | 6cpg | A | | 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1h-benzimidazol-2-yl]-1h-pyrazol-4-yl}urea | Human | 10032 | |
| AURKA (AurA) | Aur | Other | 2x81 | A | | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 1966 | |
| AURKA (AurA) | Aur | Other | 3efw | B | | 1-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea | Human | 2074 | |
| AURKA (AurA) | Aur | Other | 2bmc | C | | (3e)-n-(2,6-diethylphenyl)-3-{[4-(4-methylpiperazin-1-yl)benzoyl]imino}pyrrolo[3,4-c]pyrazole-5(3h)-carboxamide | Human | 2060 | |
| AURKA (AurA) | Aur | Other | 6vpl | B | A | phosphoaminophosphonic acid-adenylate ester | Human | 12664 | |
| AURKA (AurA) | Aur | Other | 5dr9 | A | | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 6821 | |
| AURKA (AurA) | Aur | Other | 4bn1 | A | B | adenosine-5'-diphosphate | Human | 1983 | |
| AURKA (AurA) | Aur | Other | 8guw | A | | adenosine-5'-diphosphate | Human | 14753 | |
| AURKA (AurA) | Aur | Other | 5ose | A | | adenosine-5'-diphosphate | Human | 8645 | |
| AURKA (AurA) | Aur | Other | 2xng | A | A | n-(3-{3-chloro-8-[(4-morpholin-4-ylphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzyl)methanesulfonamide | Human | 1994 | |
| AURKA (AurA) | Aur | Other | 3r22 | A | | n-{5-[(1-cycloheptyl-1h-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide | Human | 2034 | |
| AURKA (AurA) | Aur | Other | 5lxm | A | B | adenosine-5'-diphosphate | Human | 7141 | |
| AURKA (AurA) | Aur | Other | 6xka | A | | - | Human | 12665 | |
| AURKA (AurA) | Aur | Other | 2j4z | A | | 4-(4-methylpiperazin-1-yl)-n-[5-(2-thienylacetyl)-1,5-dihydropyrrolo[3,4-c]pyrazol-3-yl]benzamide | Human | 2053 | |
| AURKA (AurA) | Aur | Other | 6vph | A | A | dithiane diol | Human | 12666 | |
| AURKA (AurA) | Aur | Other | 5obr | A | | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 8304 | |
| AURKA (AurA) | Aur | Other | 4o0w | A | | adenosine | Human | 1959 | |
| AURKA (AurA) | Aur | Other | 3r21 | A | A | n-(2-aminoethyl)-n-{5-[(1-cycloheptyl-1h-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide | Human | 1991 | |
| AURKA (AurA) | Aur | Other | 4zts | A | | (2z,5z)-2-[(4-ethylphenyl)imino]-3-methyl-5-[(2-{[4-(1h-tetrazol-5-yl)phenyl]amino}pyridin-4-yl)methylidene]-1,3-thiazolidin-4-one | Human | 6814 | |
| AURKA (AurA) | Aur | Other | 6i2u | A | | - | Human | 11652 | |
| AURKA (AurA) | Aur | Other | 9sq7 | B | | adenosine-5'-diphosphate | Human | 15498 | |
| AURKA (AurA) | Aur | Other | 3h0y | A | | 2-chloro-n-[4-({5-fluoro-2-[(4-hydroxyphenyl)amino]pyrimidin-4-yl}amino)phenyl]benzamide | Human | 1965 | |
| AURKA (AurA) | Aur | Other | 4uzh | A | | (4s)-4-(2-fluorophenyl)-2,4,6,7,8,9-hexahydro-5h-pyrazolo[3,4-b][1,7]naphthyridin-5-one | Human | 1998 | |
| AURKA (AurA) | Aur | Other | 6c83 | B | | phosphomethylphosphonic acid adenylate ester | Human | 10935 | |
| AURKA (AurA) | Aur | Other | 6vpg | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 12667 | |
| AURKA (AurA) | Aur | Other | 8jg8 | A | | 4-[5-[3-[bis(oxidanylidene)-$l^5-sulfanyl]oxyphenyl]-7h-pyrrolo[2,3-d]pyrimidin-4-yl]morpholine | Human | 15272 | |
| AURKA (AurA) | Aur | Other | 9s61 | B | | adenosine-5'-diphosphate | Human | 15499 | |
| AURKA (AurA) | Aur | Other | 4o0u | A | | adenosine | Human | 2022 | |
| AURKA (AurA) | Aur | Other | 3uok | A | | 4-({4-[(2-chlorophenyl)amino]-5-fluoropyrimidin-2-yl}amino)benzoic acid | Human | 2054 | |
| AURKA (AurA) | Aur | Other | 2w1d | A | | 2-(1h-pyrazol-3-yl)-1h-benzimidazole | Human | 2011 | |
| AURKA (AurA) | Aur | Other | 2wtv | D | A | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 2078 | |
| AURKA (AurA) | Aur | Other | 9guc | A | A | adenosine-5'-diphosphate | Human | 15500 | |
| AURKA (AurA) | Aur | Other | 9bzg | A | B | 7-cyclopentyl-n,n-dimethyl-2-[4-(methylcarbamoyl)anilino]-7h-pyrrolo[2,3-d]pyrimidine-6-carboxamide | Human | 15501 | |
| AURKA (AurA) | Aur | Other | 2c6d | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 2019 | |
| AURKA (AurA) | Aur | Other | 4bn1 | A | A | adenosine-5'-diphosphate | Human | 1955 | |
| AURKA (AurA) | Aur | Other | 6vpl | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 12670 | |
| PKMYT1 (MYT1) | WEE | Other | 8wjy | A | A | [6-azanyl-5-(2,6-dimethyl-3-oxidanyl-phenyl)-2,3-dimethyl-pyrrolo[2,3-b]pyrazin-7-yl]-(6,7-dihydro-4~{h}-pyrazolo[1,5-a]pyrazin-5-yl)methanone | Human | 15008 | |
| PKMYT1 (MYT1) | WEE | Other | 5vd1 | A | B | n,1,4,4-tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 8340 | |
| PKMYT1 (MYT1) | WEE | Other | 13lx | A | | (4r)-1-cyclopentyl-4-(3-hydroxyphenyl)-1,4,5,7-tetrahydro-6h-pyrazolo[3,4-b]pyridin-6-one | Human | 15528 | |
| PKMYT1 (MYT1) | WEE | Other | 8zul | A | | 2-azanyl-5-[2-[(3~{r})-3-azanylpyrrolidin-1-yl]pyridin-4-yl]-3-(2,6-dimethyl-3-oxidanyl-phenyl)benzamide | Human | 15529 | |
| PKMYT1 (MYT1) | WEE | Other | 8zu2 | A | | 2-azanyl-5-[2-(1,4-diazepan-1-yl)pyridin-4-yl]-3-(2,6-dimethyl-3-oxidanyl-phenyl)benzamide | Human | 15530 | |
| PKMYT1 (MYT1) | WEE | Other | 13lw | A | | (4s)-1-cyclopentyl-4-(3-hydroxyphenyl)-1,4,5,7-tetrahydro-6h-pyrazolo[3,4-b]pyridin-6-one | Human | 15531 | |
| PKMYT1 (MYT1) | WEE | Other | 5vcz | A | A | 4-[(3,5-dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 8342 | |
| ULK1 | ULK | Other | 4wno | A | A | n~2~-(4-aminophenyl)-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1881 | |
| ULK1 | ULK | Other | 9f32 | A | B | n-[4-(1h-indazol-5-yl)phenyl]propanamide | Human | 15548 | |
| ULK1 | ULK | Other | 6mnh | A | A | n-[(2r)-3-methylbutan-2-yl]-1h-benzotriazole-6-carboxamide | Human | 10979 | |
| ULK1 | ULK | Other | 4wnp | A | B | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1874 | |
| ULK1 | ULK | Other | 5ci7 | A | B | n-[3-({4-[(3-aminopropyl)amino]-5-iodopyrimidin-2-yl}amino)phenyl]pyrrolidine-1-carboxamide | Human | 5973 | |
| ULK1 | ULK | Other | 8sv9 | A | B | (4p)-4-[(2p)-2-(1,2,5,6-tetrahydropyridin-3-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n-(2,2,2-trifluoroethyl)thiophene-2-carboxamide | Human | 15223 | |
| ULK1 | ULK | Other | 4wno | A | B | n~2~-(4-aminophenyl)-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1876 | |
| ULK1 | ULK | Other | 4wnp | A | A | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1878 | |
| ULK3 | ULK | Other | 6fdy | U | | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 10389 | |
| ULK3 | ULK | Other | 6fdz | U | | momelotinib | Human | 10390 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | A | A | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9716 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6ccf | A | | n-[2-oxo-3-((e)-phenyl{[4-(piperidin-1-ylmethyl)phenyl]imino}methyl)-2,6-dihydro-1h-indol-5-yl]ethanesulfonamide | Human | 9712 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | D | B | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9708 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | D | A | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9710 | |
| PRAG1 (SgK223) | NKF3 | Other | 5ve6 | A | | - | Human | 8573 | |
| AURKC (AurC) | Aur | Other | 6gr8 | A | B | 1-[(2~{r},3~{s})-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-3-methyl-6-oxidanylidene-5-[(2~{s})-1-oxidanylpropan-2-yl]-3,4-dihydro-2~{h}-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea | Human | 11125 | |
| TTK | TTK | Other | 4c4f | A | | n-(2-methoxyphenyl)-2-(1,3-oxazol-5-yl)-1h-pyrrolo[3,2-c]pyridin-6-amine | Human | 4715 | |
| IKBKB (IKKb) | IKK | Other | 4e3c | A | | - | Human | 297 | |
| NEK1 | NEK | Other | 4apc | A | A | - | Human | 1215 | |
| NEK1 | NEK | Other | 4apc | A | B | - | Human | 1208 | |
| NEK1 | NEK | Other | 4b9d | B | B | [4-(2-amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Human | 1209 | |
| NEK1 | NEK | Other | 4b9d | A | A | [4-(2-amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Human | 1211 | |
| NEK1 | NEK | Other | 4b9d | A | B | [4-(2-amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Human | 1213 | |
| NEK1 | NEK | Other | 4apc | B | B | - | Human | 1210 | |
| NEK1 | NEK | Other | 4apc | B | A | - | Human | 1212 | |
| NEK1 | NEK | Other | 4b9d | B | A | [4-(2-amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Human | 1214 | |
| BUB1 | BUB | Other | 5dmz | A | | adenosine-5'-diphosphate | Human | 6287 | |
| BUB1 | BUB | Other | 4qpm | B | | adenosine-5'-diphosphate | Human | 1844 | |
| WEE1 (Wee1) | WEE | Other | 9r56 | A | | mips-54861 | Human | 15665 | |
| WEE1 (Wee1) | WEE | Other | 5vd9 | A | | 1-{6-[(1r)-1-hydroxyethyl]pyridin-2-yl}-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-one | Human | 9781 | |
| WEE1 (Wee1) | WEE | Other | 8bju | A | B | 2-(2-methoxyphenyl)-6-[[4-(4-methylpiperazin-1-yl)phenyl]amino]-1-[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]pyrazolo[3,4-d]pyrimidin-3-one | Human | 14754 | |
| WEE1 (Wee1) | WEE | Other | 2io6 | A | | 9-hydroxy-6-(3-hydroxypropyl)-4-(2-methoxyphenyl)pyrrolo[3,4-c]carbazole-1,3(2h,6h)-dione | Human | 214 | |
| WEE1 (Wee1) | WEE | Other | 5vc6 | A | | n,1,4,4-tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 8331 | |
| WEE1 (Wee1) | WEE | Other | 3cqe | A | A | 8-bromo-4-(2-chlorophenyl)-n-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole-7-carboxamide | Human | 206 | |
| HASPIN (Haspin) | Haspin | Other | 6z57 | A | A | 10-(2-morpholin-4-ylethyl)-7-oxa-10,13,17,18,21-pentazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene | Human | 12321 | |
| EIF2AK4 (GCN2) | PEK | Other | 6n3n | A | | n-{3-[(2-aminopyrimidin-5-yl)ethynyl]-2,4-difluorophenyl}-2,5-dichloro-3-(hydroxymethyl)benzene-1-sulfonamide | Human | 11690 | |
| EIF2AK4 (GCN2) | PEK | Other | 7qwk | A | | (2~{s})-~{n}-[(1~{s})-1-[4-[(6-pyridin-4-ylquinazolin-2-yl)amino]phenyl]ethyl]piperidine-2-carboxamide | Human | 14209 | |
| EIF2AK4 (GCN2) | PEK | Other | 6n3l | B | A | n-{6-[(1-methyl-2-{[4-(trifluoromethyl)phenyl]amino}-1h-benzimidazol-5-yl)oxy]pyrimidin-4-yl}cyclopropanecarboxamide | Human | 11693 | |
| EIF2AK4 (GCN2) | PEK | Other | 6n3l | B | B | n-{6-[(1-methyl-2-{[4-(trifluoromethyl)phenyl]amino}-1h-benzimidazol-5-yl)oxy]pyrimidin-4-yl}cyclopropanecarboxamide | Human | 11692 | |
| EIF2AK4 (GCN2) | PEK | Other | 6n3l | A | B | n-{6-[(1-methyl-2-{[4-(trifluoromethyl)phenyl]amino}-1h-benzimidazol-5-yl)oxy]pyrimidin-4-yl}cyclopropanecarboxamide | Human | 11694 | |
| EIF2AK4 (GCN2) | PEK | Other | 7qq6 | A | | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | 14116 | |
| EIF2AK4 (GCN2) | PEK | Other | 8t7t | A | B | - | Human | 15230 | |
| EIF2AK3 (PEK) | PEK | Other | 4g31 | A | B | 1-[5-(4-amino-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1h-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone | Human | 2671 | |
| EIF2AK3 (PEK) | PEK | Other | 4x7l | A | B | 4-{2-amino-4-methyl-3-[2-(methylamino)-1,3-benzothiazol-6-yl]benzoyl}-1-methyl-2,5-diphenyl-1,2-dihydro-3h-pyrazol-3-one | Human | 6843 | |
| EIF2AK3 (PEK) | PEK | Other | 4x7j | A | A | 2-amino-n-[4-methoxy-3-(trifluoromethyl)phenyl]-4-methyl-3-[2-(methylamino)quinazolin-6-yl]benzamide | Human | 6848 | |
| EIF2AK3 (PEK) | PEK | Other | 8eq9 | A | B | (2r)-n-[(4m)-4-(4-amino-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-3-methylphenyl]-2-(3-fluorophenyl)-2-hydroxyacetamide | Human | 14521 | |
| EIF2AK3 (PEK) | PEK | Other | 4x7j | A | B | 2-amino-n-[4-methoxy-3-(trifluoromethyl)phenyl]-4-methyl-3-[2-(methylamino)quinazolin-6-yl]benzamide | Human | 6841 | |
| EIF2AK3 (PEK) | PEK | Other | 4x7k | A | A | 4-{2-amino-3-[5-fluoro-2-(methylamino)quinazolin-6-yl]-4-methylbenzoyl}-1-methyl-2,5-diphenyl-1,2-dihydro-3h-pyrazol-3-one | Human | 7246 | |
| EIF2AK3 (PEK) | PEK | Other | 4x7n | A | A | 4-[2-amino-4-methyl-3-(2-methylquinolin-6-yl)benzoyl]-1-methyl-2,5-diphenyl-1,2-dihydro-3h-pyrazol-3-one | Human | 7245 | |
| EIF2AK3 (PEK) | PEK | Other | 4g31 | A | A | 1-[5-(4-amino-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1h-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone | Human | 2672 | |
| EIF2AK3 (PEK) | PEK | Other | 4x7o | A | A | 1-[5-(4-amino-2,7-dimethyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1h-indol-1-yl]-2-[3-fluoro-5-(trifluoromethyl)phenyl]ethanone | Human | 7243 | |
| EIF2AK3 (PEK) | PEK | Other | 7mf0 | A | | 2-amino-n-cyclopropyl-5-(4-{[(2r)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino}-2-methylphenyl)pyridine-3-carboxamide | Human | 13577 | |
| EIF2AK3 (PEK) | PEK | Other | 8eqd | A | | (2r)-n-[(4m)-4-(4-amino-2,7-dimethyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-3-methylphenyl]-2-(3-fluorophenyl)-2-hydroxyacetamide | Human | 14523 | |
| EIF2AK3 (PEK) | PEK | Other | 8eq9 | A | A | (2r)-n-[(4m)-4-(4-amino-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-3-methylphenyl]-2-(3-fluorophenyl)-2-hydroxyacetamide | Human | 14524 | |
| EIF2AK3 (PEK) | PEK | Other | 4x7h | A | A | n-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]pyridin-2-yl}-1-methyl-3-oxo-2-phenyl-5-(pyridin-4-yl)-2,3-dihydro-1h-pyrazole-4-carboxamide | Human | 7247 | |
| EIF2AK3 (PEK) | PEK | Other | 4x7l | A | A | 4-{2-amino-4-methyl-3-[2-(methylamino)-1,3-benzothiazol-6-yl]benzoyl}-1-methyl-2,5-diphenyl-1,2-dihydro-3h-pyrazol-3-one | Human | 6844 | |
| EIF2AK3 (PEK) | PEK | Other | 4g34 | A | A | 1-[5-(4-aminothieno[3,2-c]pyridin-3-yl)-2,3-dihydro-1h-indol-1-yl]-2-phenylethanone | Human | 2674 | |
| STK16 (MPSK1) | NAK | Other | 2buj | A | | staurosporine | Human | 2229 | |
| BUB1B (BUBR1) | BUB | Other | 6tlj | S | | - | Human | 11992 | |
| WEE1 (Wee1) | WEE | Other | 5vc4 | A | | 4-[(3,5-dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 8334 | |
| EIF2AK4 (GCN2) | PEK | Other | 6n3o | A | | n-{3-[(2-aminopyrimidin-5-yl)ethynyl]-2,4-difluorophenyl}-5-chloro-2-methoxypyridine-3-sulfonamide | Human | 11695 | |
| WNK1 (Wnk1) | WNK | Other | 5wdy | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 8321 | |
| WNK1 (Wnk1) | WNK | Other | 5tf9 | A | | {2-[(4-chlorophenyl)methoxy]phenyl}{5-[2-(methylamino)-1,3-thiazol-4-yl]-2,3-dihydro-1h-indol-1-yl}methanone | Human | 7099 | |
| WNK1 (Wnk1) | WNK | Other | 5wdy | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 8326 | |
| WNK1 (Wnk1) | WNK | Other | 4pwn | A | | - | Human | 1831 | |
| WNK1 (Wnk1) | WNK | Other | 5wdy | B | B | phosphoaminophosphonic acid-adenylate ester | Human | 8322 | |
| WNK1 (Wnk1) | WNK | Other | 5tf9 | B | | {2-[(4-chlorophenyl)methoxy]phenyl}{5-[2-(methylamino)-1,3-thiazol-4-yl]-2,3-dihydro-1h-indol-1-yl}methanone | Human | 7098 | |
| WNK1 (Wnk1) | WNK | Other | 5wdy | B | A | phosphoaminophosphonic acid-adenylate ester | Human | 8323 | |
| WNK1 (Wnk1) | WNK | Other | 5we8 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 8325 | |
| WNK1 (Wnk1) | WNK | Other | 5we8 | B | A | phosphoaminophosphonic acid-adenylate ester | Human | 8327 | |
| TLK2 | TLK | Other | 5o0y | A | | phosphothiophosphoric acid-adenylate ester | Human | 9943 | |
| BMP2K (BIKE) | NAK | Other | 5i3r | B | | n-[6-(3-{[(cyclopropylmethyl)sulfonyl]amino}phenyl)-1h-indazol-3-yl]cyclopropanecarboxamide | Human | 6436 | |
| BMP2K (BIKE) | NAK | Other | 5i3r | A | | n-[6-(3-{[(cyclopropylmethyl)sulfonyl]amino}phenyl)-1h-indazol-3-yl]cyclopropanecarboxamide | Human | 6435 | |
| BMP2K (BIKE) | NAK | Other | 4w9w | A | A | 5-(3-fluorophenyl)-n-[(3s)-3-piperidyl]-3-ureido-thiophene-2-carboxamide | Human | 3274 | |
| BMP2K (BIKE) | NAK | Other | 4w9w | A | B | 5-(3-fluorophenyl)-n-[(3s)-3-piperidyl]-3-ureido-thiophene-2-carboxamide | Human | 3272 | |
| NEK2 | NEK | Other | 2w5h | A | A | - | Human | 327 | |
| NEK2 | NEK | Other | 2xk7 | A | A | (3r,4r)-1-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]-3-ethylpiperidine-4-carboxylic acid | Human | 326 | |
| NEK2 | NEK | Other | 2xk3 | A | A | 4-[3-amino-6-(3-ethylthiophen-2-yl)pyrazin-2-yl]cyclohexane-1-carboxylic acid | Human | 309 | |
| NEK2 | NEK | Other | 2w5a | A | A | adenosine-5'-diphosphate | Human | 302 | |
| NEK2 | NEK | Other | 2xkc | A | B | 4-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]-2-methylbenzoic acid | Human | 307 | |
| NEK2 | NEK | Other | 2xke | A | | 1-[3-amino-6-(3-methoxyphenyl)pyrazin-2-yl]piperidine-4-carboxylic acid | Human | 299 | |
| NEK2 | NEK | Other | 2xkc | A | A | 4-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]-2-methylbenzoic acid | Human | 321 | |
| NEK2 | NEK | Other | 2xk8 | A | | 4-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]-2-methoxybenzoic acid | Human | 300 | |
| NEK2 | NEK | Other | 6sgh | A | B | 2-[4-[(6-ethenyl-9~{h}-purin-2-yl)amino]phenyl]ethanamide | Human | 12372 | |
| NEK2 | NEK | Other | 2jav | A | B | 5-[(z)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 323 | |
| NEK2 | NEK | Other | 2jav | A | A | 5-[(z)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 332 | |
| NEK2 | NEK | Other | 2xno | A | A | 5-{6-[(1-methylpiperidin-4-yl)oxy]-1h-benzimidazol-1-yl}-3-{[2-(trifluoromethyl)benzyl]oxy}thiophene-2-carboxamide | Human | 319 | |
| NEK2 | NEK | Other | 5m55 | A | A | 6-[(~{z})-2-(diethylamino)ethenyl]-~{n}-phenyl-7~{h}-purin-2-amine | Human | 7140 | |
| NEK2 | NEK | Other | 4afe | A | | 4-(2-amino-5-{4-[(dimethylamino)methyl]thiophen-2-yl}pyridin-3-yl)-2-{[(1r,2z)-4,4,4-trifluoro-1-methylbut-2-en-1-yl]oxy}benzamide | Human | 312 | |
| NEK2 | NEK | Other | 4a4x | A | | 4-(2-amino-5-{4-[(dimethylamino)methyl]thiophen-2-yl}pyridin-3-yl)-2-{(1r)-1-[2-(trifluoromethyl)phenyl]ethoxy}benzamide | Human | 325 | |
| NEK2 | NEK | Other | 6sgd | A | A | 4-[(6-ethenyl-7~{h}-purin-2-yl)amino]benzenesulfonamide | Human | 12373 | |
| NEK2 | NEK | Other | 2w5h | A | B | - | Human | 310 | |
| NEK2 | NEK | Other | 2xkd | A | A | 4-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]benzoic acid | Human | 330 | |
| NEK2 | NEK | Other | 2xnm | A | B | 5-{6-[(1-methylpiperidin-4-yl)oxy]-1h-benzimidazol-1-yl}-3-{(1r)-1-[2-(trifluoromethyl)phenyl]ethoxy}thiophene-2-carboxamide | Human | 324 | |
| NEK2 | NEK | Other | 2xnn | A | B | 5-(1h-benzimidazol-1-yl)-3-{(1r)-1-[2-(trifluoromethyl)phenyl]ethoxy}thiophene-2-carboxamide | Human | 308 | |
| NEK2 | NEK | Other | 2xk4 | A | C | 4-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]-2-ethoxybenzoic acid | Human | 304 | |
| NEK2 | NEK | Other | 2xk3 | A | B | 4-[3-amino-6-(3-ethylthiophen-2-yl)pyrazin-2-yl]cyclohexane-1-carboxylic acid | Human | 329 | |
| NEK2 | NEK | Other | 5m55 | A | B | 6-[(~{z})-2-(diethylamino)ethenyl]-~{n}-phenyl-7~{h}-purin-2-amine | Human | 7139 | |
| NEK2 | NEK | Other | 5m57 | A | | o6-cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine | Human | 7272 | |
| NEK2 | NEK | Other | 2xk4 | A | B | 4-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]-2-ethoxybenzoic acid | Human | 316 | |
| NEK2 | NEK | Other | 2w5a | A | B | adenosine-5'-diphosphate | Human | 317 | |
| NEK2 | NEK | Other | 2xk7 | A | B | (3r,4r)-1-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]-3-ethylpiperidine-4-carboxylic acid | Human | 318 | |
| NEK2 | NEK | Other | 2xk4 | A | A | 4-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]-2-ethoxybenzoic acid | Human | 314 | |
| NEK2 | NEK | Other | 2xnn | A | A | 5-(1h-benzimidazol-1-yl)-3-{(1r)-1-[2-(trifluoromethyl)phenyl]ethoxy}thiophene-2-carboxamide | Human | 303 | |
| NEK2 | NEK | Other | 6sgk | A | | 2-phenylazanyl-9~{h}-purine-6-carbonitrile | Human | 12377 | |
| NEK2 | NEK | Other | 2wqo | A | | 4-[2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]benzoic acid | Human | 331 | |
| NEK2 | NEK | Other | 6sgi | A | A | 4-[(6-ethyl-7~{h}-purin-2-yl)amino]benzenesulfonamide | Human | 12378 | |
| NEK2 | NEK | Other | 6sk9 | A | B | 3-[[6-(cyclohexylmethoxy)-7~{h}-purin-2-yl]amino]-~{n}-[3-(dimethylamino)propyl]benzenesulfonamide | Human | 12379 | |
| NEK2 | NEK | Other | 5m51 | A | | 3-[[6-(cyclohexylmethoxy)-9~{h}-purin-2-yl]amino]benzamide | Human | 7157 | |
| NEK2 | NEK | Other | 2xno | A | B | 5-{6-[(1-methylpiperidin-4-yl)oxy]-1h-benzimidazol-1-yl}-3-{[2-(trifluoromethyl)benzyl]oxy}thiophene-2-carboxamide | Human | 313 | |
| NEK2 | NEK | Other | 5m53 | A | B | 3-[[6-(cyclohexylmethoxy)-7~{h}-purin-2-yl]amino]-~{n},~{n}-dimethyl-benzamide | Human | 7161 | |
| NEK2 | NEK | Other | 6sgi | A | B | 4-[(6-ethyl-7~{h}-purin-2-yl)amino]benzenesulfonamide | Human | 12380 | |
| NEK2 | NEK | Other | 2xnp | A | A | 4-{5-[(1-methylpiperidin-4-yl)oxy]-1h-benzimidazol-1-yl}-2-{(1r)-1-[2-(trifluoromethyl)phenyl]ethoxy}benzamide | Human | 328 | |
| NEK2 | NEK | Other | 2xkd | A | B | 4-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]benzoic acid | Human | 298 | |
| NEK2 | NEK | Other | 2xnm | A | A | 5-{6-[(1-methylpiperidin-4-yl)oxy]-1h-benzimidazol-1-yl}-3-{(1r)-1-[2-(trifluoromethyl)phenyl]ethoxy}thiophene-2-carboxamide | Human | 306 | |
| NEK2 | NEK | Other | 2xk6 | A | | cis-4-[3-amino-6-(3-cyclopropylthiophen-2-yl)pyrazin-2-yl]cyclohexanecarboxylic acid | Human | 301 | |
| AURKB (AurB) | Aur | Other | 4af3 | A | | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 407 | |
| NEK7 | NEK | Other | 5de2 | A | A | - | Human | 6246 | |
| NEK7 | NEK | Other | 6s73 | B | | 3-[[6-(cyclohexylmethoxy)-7~{h}-purin-2-yl]amino]-~{n}-[3-(dimethylamino)propyl]benzenesulfonamide | Human | 12353 | |
| NEK7 | NEK | Other | 6s76 | B | | - | Human | 12354 | |
| NEK7 | NEK | Other | 5de2 | B | A | - | Human | 6245 | |
| NEK7 | NEK | Other | 6s73 | D | | - | Human | 12355 | |
| NEK7 | NEK | Other | 6npy | B | A | - | Human | 11338 | |
| NEK7 | NEK | Other | 6s75 | A | | 3-[[6-(cyclohexylmethoxy)-7~{h}-purin-2-yl]amino]-~{n}-[3-(dimethylamino)propyl]benzenesulfonamide | Human | 12356 | |
| NEK7 | NEK | Other | 6s73 | A | | 3-[[6-(cyclohexylmethoxy)-7~{h}-purin-2-yl]amino]-~{n}-[3-(dimethylamino)propyl]benzenesulfonamide | Human | 12357 | |
| NEK7 | NEK | Other | 6s75 | B | | 3-[[6-(cyclohexylmethoxy)-7~{h}-purin-2-yl]amino]-~{n}-[3-(dimethylamino)propyl]benzenesulfonamide | Human | 12358 | |
| NEK7 | NEK | Other | 2wqn | A | B | adenosine-5'-diphosphate | Human | 3856 | |
| NEK7 | NEK | Other | 6npy | B | B | - | Human | 11337 | |
| NEK7 | NEK | Other | 6s75 | D | | - | Human | 12359 | |
| NEK7 | NEK | Other | 6s75 | C | | 3-[[6-(cyclohexylmethoxy)-7~{h}-purin-2-yl]amino]-~{n}-[3-(dimethylamino)propyl]benzenesulfonamide | Human | 12360 | |
| NEK7 | NEK | Other | 2wqm | A | A | - | Human | 3854 | |
| NEK7 | NEK | Other | 5de2 | B | B | - | Human | 6247 | |
| NEK7 | NEK | Other | 5de2 | A | B | - | Human | 6244 | |
| NEK7 | NEK | Other | 6s73 | C | | 3-[[6-(cyclohexylmethoxy)-7~{h}-purin-2-yl]amino]-~{n}-[3-(dimethylamino)propyl]benzenesulfonamide | Human | 12362 | |
| NEK7 | NEK | Other | 2wqm | A | B | - | Human | 3857 | |
| PLK4 | PLK | Other | 9o63 | A | | 5-cyclopropyl-n~2~-[2,6-difluoro-4-(methanesulfonyl)phenyl]-n~2~-methyl-6-(1-methyl-1h-imidazol-4-yl)-n~4~-(5-methyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | 16032 | |
| ULK2 | ULK | Other | 6qau | B | A | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 11222 | |
| ULK2 | ULK | Other | 9se9 | A | A | ~{n}4-cyclopropyl-~{n}2-(1,2,3,4-tetrahydroisoquinolin-6-yl)-5-(trifluoromethyl)pyrimidine-2,4-diamine | Human | 16035 | |
| ULK2 | ULK | Other | 6yid | B | A | 2-({5-bromo-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}oxy)-n-methylbenzene-1-carboximidic acid | Human | 12381 | |
| ULK2 | ULK | Other | 6qav | C | A | ~{n}-[3-[[5-cyclopropyl-2-[(2-methyl-3,4-dihydro-1~{h}-isoquinolin-6-yl)amino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide | Human | 11223 | |
| ULK2 | ULK | Other | 6yid | A | B | 2-({5-bromo-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}oxy)-n-methylbenzene-1-carboximidic acid | Human | 12382 | |
| ULK2 | ULK | Other | 6qat | D | | n-{(3z)-2-oxo-3-[phenyl({4-[(piperidin-1-yl)methyl]phenyl}amino)methylidene]-2,3-dihydro-1h-indol-5-yl}ethanesulfonamide | Human | 11230 | |
| ULK2 | ULK | Other | 6qat | C | | n-{(3z)-2-oxo-3-[phenyl({4-[(piperidin-1-yl)methyl]phenyl}amino)methylidene]-2,3-dihydro-1h-indol-5-yl}ethanesulfonamide | Human | 11232 | |
| ULK2 | ULK | Other | 6qau | B | B | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 11236 | |
| ULK2 | ULK | Other | 6qav | A | A | ~{n}-[3-[[5-cyclopropyl-2-[(2-methyl-3,4-dihydro-1~{h}-isoquinolin-6-yl)amino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide | Human | 11231 | |
| ULK2 | ULK | Other | 6qau | C | B | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 11233 | |
| ULK2 | ULK | Other | 6yid | A | A | 2-({5-bromo-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}oxy)-n-methylbenzene-1-carboximidic acid | Human | 12385 | |
| ULK2 | ULK | Other | 6qat | A | | n-{(3z)-2-oxo-3-[phenyl({4-[(piperidin-1-yl)methyl]phenyl}amino)methylidene]-2,3-dihydro-1h-indol-5-yl}ethanesulfonamide | Human | 11227 | |
| ULK2 | ULK | Other | 6yid | C | B | 2-({5-bromo-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}oxy)-n-methylbenzene-1-carboximidic acid | Human | 12386 | |
| ULK2 | ULK | Other | 6qau | A | B | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 11225 | |
| ULK2 | ULK | Other | 6qau | A | A | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 11235 | |
| ULK2 | ULK | Other | 9se9 | A | B | ~{n}4-cyclopropyl-~{n}2-(1,2,3,4-tetrahydroisoquinolin-6-yl)-5-(trifluoromethyl)pyrimidine-2,4-diamine | Human | 16036 | |
| ULK2 | ULK | Other | 6qav | B | A | ~{n}-[3-[[5-cyclopropyl-2-[(2-methyl-3,4-dihydro-1~{h}-isoquinolin-6-yl)amino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide | Human | 11224 | |
| ULK2 | ULK | Other | 6yid | D | A | 2-({5-bromo-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}oxy)-n-methylbenzene-1-carboximidic acid | Human | 12388 | |
| WEE2 (Wee1B) | WEE | Other | 5vdk | A | | 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-one | Human | 8349 | |
| TTK | TTK | Other | 6gvj | A | | - | Human | 10847 | |
| TTK | TTK | Other | 4bi0 | A | | 5h-pyrimido[5,4-b]indole | Human | 4702 | |
| TTK | TTK | Other | 5ntt | A | B | n-(2,6-diethylphenyl)-1-methyl-8-({4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)phenyl}amino)-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 8267 | |
| TTK | TTK | Other | 3gfw | A | | 1-(4-(4-(2-(isopropylsulfonyl)phenylamino)-1h-pyrrolo[2,3-b]pyridin-6-ylamino)-3-methoxyphenyl)piperidin-4-ol | Human | 4714 | |
| TTK | TTK | Other | 5ehl | A | | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]urea | Human | 7256 | |
| TTK | TTK | Other | 5mrb | A | | ~{n}-(2,6-diethylphenyl)-8-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 8270 | |
| TTK | TTK | Other | 4c4i | A | | tert-butyl 6-{[2-chloro-4-(dimethylcarbamoyl)phenyl]amino}-2-(1,3-oxazol-5-yl)-1h-pyrrolo[3,2-c]pyridine-1-carboxylate | Human | 4698 | |
| TTK | TTK | Other | 3wyy | A | | (2e)-3-[4-({4-amino-5-cyano-6-[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]dec-1-ylamino]pyridin-2-yl}amino)-2-(cyanomethoxy)phenyl]-n-(2-methoxyethyl)prop-2-enamide | Human | 4711 | |
| TTK | TTK | Other | 6tnb | A | | (2~{r})-2-(4-fluorophenyl)-~{n}-[4-[2-[(2-methoxy-4-methylsulfonyl-phenyl)amino]-[1,2,4]triazolo[1,5-a]pyridin-6-yl]phenyl]propanamide | Human | 12267 | |
| TTK | TTK | Other | 3wyx | A | | 6-{[3-(cyanomethoxy)-4-(1-methyl-1h-pyrazol-4-yl)phenyl]amino}-2-(cyclohexylamino)pyridine-3-carbonitrile | Human | 4721 | |
| TTK | TTK | Other | 5ei6 | A | | ~{n}-(2,4-dimethoxyphenyl)-5-(1-methylpyrazol-4-yl)isoquinolin-3-amine | Human | 6558 | |
| TTK | TTK | Other | 6h3k | A | | ~{n}8-(2,2-dimethylpropyl)-~{n}2-[2-ethoxy-4-(4-methyl-1,2,4-triazol-3-yl)phenyl]-6-methyl-pyrido[3,4-d]pyrimidine-2,8-diamine | Human | 10571 | |
| TTK | TTK | Other | 4bi2 | A | | thieno[2,3-c][2,7]naphthyridine | Human | 4700 | |
| TTK | TTK | Other | 2x9e | A | | n-(2,6-diethylphenyl)-1-methyl-8-({4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)phenyl}amino)-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 4729 | |
| TTK | TTK | Other | 3w1f | A | | 5-[5-ethoxy-6-(1-methyl-1h-pyrazol-4-yl)-1h-indazol-3-yl]-2-methylbenzenesulfonamide | Human | 4722 | |
| TTK | TTK | Other | 4c4j | A | | tert-butyl 6-{[2-chloro-4-(1-methyl-1h-imidazol-5-yl)phenyl]amino}-2-(1-methyl-1h-pyrazol-4-yl)-1h-pyrrolo[3,2-c]pyridine-1-carboxylate | Human | 4723 | |
| TTK | TTK | Other | 7cja | A | | 4-(cyclopentylmethylamino)-2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | 13551 | |
| TTK | TTK | Other | 3wzj | A | | 4-{6-(cyclohexylamino)-8-[(tetrahydro-2h-pyran-4-ylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}-n-cyclopropylbenzamide | Human | 4704 | |
| TTK | TTK | Other | 5ei8 | A | | ~{n}-[2-methoxy-4-(1-methylpyrazol-4-yl)phenyl]-8-(1-methylpyrazol-4-yl)pyrido[3,4-d]pyrimidin-2-amine | Human | 6557 | |
| TTK | TTK | Other | 6b4w | A | | 4-{[4-(cyclopentyloxy)-5-(2-methyl-1,3-benzoxazol-6-yl)-7h-pyrrolo[2,3-d]pyrimidin-2-yl]amino}-3-methoxy-n-methylbenzamide | Human | 8616 | |
| TTK | TTK | Other | 7clh | A | | 2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-4-(methylamino)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | 13553 | |
| TTK | TTK | Other | 3hmn | A | | adenosine-5'-triphosphate | Human | 4719 | |
| TTK | TTK | Other | 4cva | A | | n-(6-oxo-1,6-dihydro-3,4'-bipyridin-5-yl)-4-(piperidin-1-yl)benzamide | Human | 4713 | |
| TTK | TTK | Other | 3vqu | A | | 4-[(4-amino-5-cyano-6-ethoxypyridin-2-yl)amino]benzamide | Human | 4718 | |
| TTK | TTK | Other | 4cv9 | A | | 4-(4-methylpiperazin-1-yl)-n-(2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridin-3-yl)benzamide | Human | 4705 | |
| TTK | TTK | Other | 5ap1 | A | | 6-{[3-(cyanomethoxy)-4-(1-methyl-1h-pyrazol-4-yl)phenyl]amino}-2-(cyclohexylamino)pyridine-3-carbonitrile | Human | 6103 | |
| TTK | TTK | Other | 6n6o | A | | 4-({5-chloro-4-[(cis-4-hydroxy-4-methylcyclohexyl)oxy]-7h-pyrrolo[2,3-d]pyrimidin-2-yl}amino)-n,n-dimethyl-3-{[(2r)-1,1,1-trifluoropropan-2-yl]oxy}benzamide | Human | 11240 | |
| TTK | TTK | Other | 5ntt | A | A | n-(2,6-diethylphenyl)-1-methyl-8-({4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)phenyl}amino)-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 8268 | |
| TTK | TTK | Other | 6tnd | A | A | bay 1217389 | Human | 12268 | |
| TTK | TTK | Other | 4js8 | A | | 4-(cyclohexylmethoxy)-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-2h-indazole | Human | 4724 | |
| TTK | TTK | Other | 4bhz | A | | thieno[2,3-c][2,6]naphthyridine | Human | 4709 | |
| TTK | TTK | Other | 7cht | A | | 2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-4-(oxan-4-ylamino)-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | 13554 | |
| TTK | TTK | Other | 6tn9 | A | B | [4-[[6-(3,5-dimethyl-4-oxidanyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]phenyl]-morpholin-4-yl-methanone | Human | 12269 | |
| TTK | TTK | Other | 5ei2 | A | | ~{n}-(2,4-dimethoxyphenyl)-8-(1-methylpyrazol-4-yl)pyrido[3,4-d]pyrimidin-2-amine | Human | 6559 | |
| TTK | TTK | Other | 4d2s | A | | n-{2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]phenyl}-4-(1h-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine | Human | 4717 | |
| TTK | TTK | Other | 3hmp | A | | 7-chloro-n-(cyclopropylmethyl)quinazolin-4-amine | Human | 4728 | |
| TTK | TTK | Other | 5ap7 | A | | n-(2,6-diethylphenyl)-1-methyl-8-({4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)phenyl}amino)-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 6100 | |
| TTK | TTK | Other | 2zmd | A | | 2,6-dihydroanthra/1,9-cd/pyrazol-6-one | Human | 4731 | |
| TTK | TTK | Other | 5ap4 | A | | 6-{[3-(cyanomethoxy)-4-(1-methyl-1h-pyrazol-4-yl)phenyl]amino}-2-(cyclohexylamino)pyridine-3-carbonitrile | Human | 6097 | |
| TTK | TTK | Other | 2zmc | A | | - | Human | 4696 | |
| TTK | TTK | Other | 5o91 | A | | ~{n}-(2,6-diethylphenyl)-8-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 8269 | |
| TTK | TTK | Other | 4zeg | A | | n-cyclopropyl-2-methyl-4-(7-{[2-(morpholin-4-yl)ethyl]amino}-5-phenoxypyrazolo[1,5-a]pyrimidin-3-yl)benzamide | Human | 6574 | |
| TTK | TTK | Other | 7lqd | A | | ~{n}-(2,6-diethylphenyl)-2-[[4-(4-methylpiperazin-1-yl)-2-(propanoylamino)phenyl]amino]-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide | Human | 14108 | |
| TTK | TTK | Other | 6tn9 | A | A | [4-[[6-(3,5-dimethyl-4-oxidanyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]phenyl]-morpholin-4-yl-methanone | Human | 12271 | |
| TTK | TTK | Other | 5ap6 | A | B | isopropyl 6-((4-(1,2-dimethyl-1h-imidazol-5-yl)phenyl)amino)-2-(1-methyl-1h-pyrazol-4-yl)-1h-pyrrolo[3,2-c]pyridine-1-carboxylate | Human | 6102 | |
| TTK | TTK | Other | 3cek | A | | - | Human | 4716 | |
| TTK | TTK | Other | 4cv8 | A | | 3-amino-5-(1-methyl-1h-pyrazol-4-yl)pyridin-2(1h)-one | Human | 4706 | |
| TTK | TTK | Other | 4c4h | A | | tert-butyl 6-((2-chloro-4-(dimethylcarbamoyl)phenyl)amino)-2-(1-methyl-1h-pyrazol-4-yl)-1h-pyrrolo[3,2-c]pyridine-1-carboxylate | Human | 4725 | |
| TTK | TTK | Other | 3dbq | A | | - | Human | 4710 | |
| IKBKB (IKKb) | IKK | Other | 4e3c | C | | - | Human | 296 | |
| IKBKB (IKKb) | IKK | Other | 4e3c | F | | - | Human | 292 | |
| IKBKB (IKKb) | IKK | Other | 4kik | A | A | k-252a | Human | 290 | |
| IKBKB (IKKb) | IKK | Other | 4kik | B | A | k-252a | Human | 295 | |
| IKBKB (IKKb) | IKK | Other | 4e3c | D | | - | Human | 291 | |
| HASPIN (Haspin) | Haspin | Other | 6z59 | A | B | 11-oxa-8,14,18,19,22-pentazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2,4,6(23),15(22),16,19-heptaen-7-one | Human | 12316 | |
| HASPIN (Haspin) | Haspin | Other | 4ouc | A | A | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 3806 | |
| HASPIN (Haspin) | Haspin | Other | 3f2n | A | B | (2s)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-ol | Human | 3813 | |
| HASPIN (Haspin) | Haspin | Other | 6z5e | A | A | 11-cyclopropyl-14-(2-hydroxyethyl)-8,11,14,18,19,22-hexazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2(23),3,5,15(22),16,19-heptaen-7-one | Human | 12317 | |
| HASPIN (Haspin) | Haspin | Other | 6z5c | A | B | 7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxylic acid | Human | 12318 | |
| HASPIN (Haspin) | Haspin | Other | 9flo | A | | ~{n}-(1,4-dimethylpyrazol-3-yl)-3-(1,2-thiazol-5-yl)thieno[3,2-b]pyridin-5-amine | Human | 16109 | |
| HASPIN (Haspin) | Haspin | Other | 7sqm | A | B | 1-[(4s)-5-(2,4-difluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-4-methylpiperidin-4-amine | Human | 14032 | |
| HASPIN (Haspin) | Haspin | Other | 6g39 | A | A | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 9839 | |
| HASPIN (Haspin) | Haspin | Other | 6z5c | A | A | 7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxylic acid | Human | 12319 | |
| HASPIN (Haspin) | Haspin | Other | 5htb | A | A | - | Human | 6620 | |
| HASPIN (Haspin) | Haspin | Other | 9flb | A | A | 5-(1-methylpyrazol-4-yl)-3-pyridin-4-yl-thieno[3,2-b]pyridine | Human | 16110 | |
| HASPIN (Haspin) | Haspin | Other | 9flt | A | | ~{n}-(1,4-dimethylpyrazol-3-yl)-3-pyridin-4-yl-thieno[3,2-b]pyridin-5-amine | Human | 16111 | |
| HASPIN (Haspin) | Haspin | Other | 3f2n | A | A | (2s)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-ol | Human | 3803 | |
| HASPIN (Haspin) | Haspin | Other | 6z56 | A | A | 6-(2-methoxyethoxy)-11-methyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one | Human | 12322 | |
| HASPIN (Haspin) | Haspin | Other | 9flb | A | B | 5-(1-methylpyrazol-4-yl)-3-pyridin-4-yl-thieno[3,2-b]pyridine | Human | 16114 | |
| HASPIN (Haspin) | Haspin | Other | 7avq | A | B | (2~{r})-2-[[3-(2~{h}-indazol-5-yl)imidazo[1,2-b]pyridazin-6-yl]amino]butan-1-ol | Human | 13175 | |
| HASPIN (Haspin) | Haspin | Other | 6z57 | A | B | 10-(2-morpholin-4-ylethyl)-7-oxa-10,13,17,18,21-pentazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene | Human | 12323 | |
| HASPIN (Haspin) | Haspin | Other | 2vuw | A | A | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 3809 | |
| HASPIN (Haspin) | Haspin | Other | 5htc | A | B | - | Human | 6446 | |
| HASPIN (Haspin) | Haspin | Other | 3e7v | A | A | 3-(3-aminophenyl)-n-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-amine | Human | 3814 | |
| HASPIN (Haspin) | Haspin | Other | 6z5a | A | B | n-cyclopentyl-2-[(11,15-dimethyl-10-oxo-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-6-yl)oxy]acetamide | Human | 12324 | |
| HASPIN (Haspin) | Haspin | Other | 6g35 | A | D | - | Human | 9829 | |
| HASPIN (Haspin) | Haspin | Other | 3fmd | A | B | n-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide | Human | 3810 | |
| HASPIN (Haspin) | Haspin | Other | 6g36 | A | B | 5-chlorotubercidin | Human | 9844 | |
| HASPIN (Haspin) | Haspin | Other | 9flc | A | B | 5-(1-methylpyrazol-3-yl)-3-pyridin-4-yl-thieno[3,2-b]pyridine | Human | 16115 | |
| HASPIN (Haspin) | Haspin | Other | 3dlz | A | B | adenosine monophosphate | Human | 3808 | |
| HASPIN (Haspin) | Haspin | Other | 5htc | A | C | - | Human | 6444 | |
| HASPIN (Haspin) | Haspin | Other | 6g36 | A | A | 5-chlorotubercidin | Human | 9834 | |
| HASPIN (Haspin) | Haspin | Other | 6g35 | A | B | 5-bromotubercidin | Human | 9841 | |
| HASPIN (Haspin) | Haspin | Other | 6g3a | A | A | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 9836 | |
| HASPIN (Haspin) | Haspin | Other | 5htb | A | B | - | Human | 6621 | |
| HASPIN (Haspin) | Haspin | Other | 5htc | A | A | - | Human | 6445 | |
| HASPIN (Haspin) | Haspin | Other | 6g39 | A | B | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 9831 | |
| HASPIN (Haspin) | Haspin | Other | 6z5d | A | A | 11-methyl-8,11,14,18,19,22-hexazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2(23),3,5,15(22),16,19-heptaen-7-one | Human | 12325 | |
| HASPIN (Haspin) | Haspin | Other | 6z59 | A | A | 11-oxa-8,14,18,19,22-pentazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2,4,6(23),15(22),16,19-heptaen-7-one | Human | 12326 | |
| HASPIN (Haspin) | Haspin | Other | 2wb8 | A | A | - | Human | 3802 | |
| HASPIN (Haspin) | Haspin | Other | 3e7v | A | B | 3-(3-aminophenyl)-n-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-amine | Human | 3799 | |
| HASPIN (Haspin) | Haspin | Other | 6z58 | A | A | 8,14,18,19,22-pentazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2,4,6(23),15(22),16,19-heptaen-7-one | Human | 12327 | |
| HASPIN (Haspin) | Haspin | Other | 6g39 | A | D | - | Human | 9833 | |
| HASPIN (Haspin) | Haspin | Other | 3iq7 | A | A | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 3807 | |
| HASPIN (Haspin) | Haspin | Other | 6g35 | A | C | - | Human | 9837 | |
| HASPIN (Haspin) | Haspin | Other | 6z5a | A | A | n-cyclopentyl-2-[(11,15-dimethyl-10-oxo-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-6-yl)oxy]acetamide | Human | 12328 | |
| HASPIN (Haspin) | Haspin | Other | 4ouc | A | B | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 3812 | |
| HASPIN (Haspin) | Haspin | Other | 3fmd | A | A | n-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide | Human | 3798 | |
| HASPIN (Haspin) | Haspin | Other | 6g34 | A | A | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 9832 | |
| HASPIN (Haspin) | Haspin | Other | 3dlz | A | A | adenosine monophosphate | Human | 3804 | |
| HASPIN (Haspin) | Haspin | Other | 6z58 | A | B | 8,14,18,19,22-pentazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2,4,6(23),15(22),16,19-heptaen-7-one | Human | 12332 | |
| HASPIN (Haspin) | Haspin | Other | 4qtc | A | B | (3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamide | Human | 3800 | |
| HASPIN (Haspin) | Haspin | Other | 3iq7 | A | B | (2r,3r,4s,5r)-2-(4-amino-5-iodo-7h-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Human | 3811 | |
| TP53RK (PRPK) | Bud32 | Other | 6wqx | C | | phosphoaminophosphonic acid-adenylate ester | Human | 13338 | |
| TP53RK (PRPK) | Bud32 | Other | 7szb | A | | 5-amino-2-[(3r)-2,6-dioxopiperidin-3-yl]-1h-isoindole-1,3(2h)-dione | Human | 14598 | |
| TP53RK (PRPK) | Bud32 | Other | 9fl9 | B | | - | Human | 16219 | |
| AAK1 | NAK | Other | 5l4q | A | A | ~{n}-[5-(4-cyanophenyl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide | Human | 6679 | |
| AAK1 | NAK | Other | 4wsq | B | B | k-252a | Human | 3835 | |
| AAK1 | NAK | Other | 4wsq | A | A | k-252a | Human | 3834 | |
| AAK1 | NAK | Other | 5l4q | B | B | ~{n}-[5-(4-cyanophenyl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide | Human | 6678 | |
| AAK1 | NAK | Other | 4wsq | B | A | k-252a | Human | 3833 | |
| AAK1 | NAK | Other | 4wsq | A | B | k-252a | Human | 3836 | |
