Search results (24 entries covering 6 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
| PTK6 (BRK) | Src | TK | 5h2u | C | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7342 | ||
| PTK6 (BRK) | Src | TK | 5da3 | A | B | (2-chloro-4-{[6-cyclopropyl-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone | Human | 6988 | ||
| PTK6 (BRK) | Src | TK | 6cz2 | A | B | - | Human | 10031 | ||
| PTK6 (BRK) | Src | TK | 5d7v | B | B | - | Human | 6951 | ||
| PTK6 (BRK) | Src | TK | 5d7v | C | B | - | Human | 6954 | ||
| PTK6 (BRK) | Src | TK | 6cz3 | A | A | (3-fluoro-4-{[6-methyl-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone | Human | 10001 | ||
| PTK6 (BRK) | Src | TK | 5da3 | A | A | (2-chloro-4-{[6-cyclopropyl-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone | Human | 6989 | ||
| PTK6 (BRK) | Src | TK | 6cz2 | A | A | - | Human | 10030 | ||
| PTK6 (BRK) | Src | TK | 6cz4 | A | A | 2-{[(3r,4s)-3-fluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl]oxy}-5-(1-methyl-1h-imidazol-4-yl)pyridine-3-carboxamide | Human | 9998 | ||
| PTK6 (BRK) | Src | TK | 5h2u | C | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7341 | ||
| PTK6 (BRK) | Src | TK | 5d7v | C | A | - | Human | 6949 | ||
| PTK6 (BRK) | Src | TK | 5h2u | A | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7343 | ||
| PTK6 (BRK) | Src | TK | 5d7v | D | B | - | Human | 6952 | ||
| PTK6 (BRK) | Src | TK | 5d7v | D | A | - | Human | 6948 | ||
| PTK6 (BRK) | Src | TK | 5h2u | D | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7340 | ||
| PTK6 (BRK) | Src | TK | 5h2u | B | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7337 | ||
| PTK6 (BRK) | Src | TK | 5d7v | A | A | - | Human | 6953 | ||
| PTK6 (BRK) | Src | TK | 5h2u | D | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7344 | ||
| PTK6 (BRK) | Src | TK | 6cz3 | A | B | (3-fluoro-4-{[6-methyl-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone | Human | 9999 | ||
| PTK6 (BRK) | Src | TK | 5d7v | A | B | - | Human | 6950 | ||
| PTK6 (BRK) | Src | TK | 5d7v | B | A | - | Human | 6955 | ||
| PTK6 (BRK) | Src | TK | 5h2u | B | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7339 | ||
| PTK6 (BRK) | Src | TK | 5h2u | A | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 7338 | ||
| PTK6 (BRK) | Src | TK | 6cz4 | A | B | 2-{[(3r,4s)-3-fluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl]oxy}-5-(1-methyl-1h-imidazol-4-yl)pyridine-3-carboxamide | Human | 10000 |