Search results (23 entries covering 21 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
| CDK6 | CDK | CMGC | 3nux | A | 4-[5-chloro-3-(1-methylethyl)-1h-pyrazol-4-yl]-n-(5-piperazin-1-ylpyridin-2-yl)pyrimidin-2-amine | Human | 2807 | |||
| CDK6 | CDK | CMGC | 5l2t | A | 7-cyclopentyl-n,n-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7h-pyrrolo[2,3-d]pyrimidine-6-carboxamide | Human | 6992 | |||
| CDK6 | CDK | CMGC | 8i0m | A | 2-[(4-azanylcyclohexyl)amino]-7-cyclopentyl-~{n},~{n}-dimethyl-pyrrolo[2,3-d]pyrimidine-6-carboxamide | Human | 15164 | |||
| CDK6 | CDK | CMGC | 2f2c | B | (2s)-2-({6-[(3-amino-5-chlorophenyl)amino]-9-isopropyl-9h-purin-2-yl}amino)-3-methylbutan-1-ol | Human | 2795 | |||
| CDK6 | CDK | CMGC | 4aua | A | 1h-benzimidazol-2-yl(1h-pyrrol-2-yl)methanone | Human | 2801 | |||
| CDK6 | CDK | CMGC | 6oqo | A | n-[5-(6-ethyl-2,6-diazaspiro[3.3]heptan-2-yl)pyridin-2-yl]-5-fluoro-4-[(4r)-4-methyl-5,6,7,8-tetrahydro-4h-pyrazolo[1,5-a]azepin-3-yl]pyrimidin-2-amine | Human | 12646 | |||
| CDK6 | CDK | CMGC | 9d8u | A | atirmociclib | Human | 15857 | |||
| CDK6 | CDK | CMGC | 1g3n | A | - | Human | 2806 | |||
| CDK6 | CDK | CMGC | 1bi7 | A | - | Human | 2798 | |||
| CDK6 | CDK | CMGC | 1blx | A | - | Human | 2802 | |||
| CDK6 | CDK | CMGC | 1bi8 | A | - | Human | 2796 | |||
| CDK6 | CDK | CMGC | 6oql | A | 5-fluoro-n-[5-(4-methylpiperazin-1-yl)pyridin-2-yl]-4-[(4r)-4-methyl-5,6,7,8-tetrahydro-4h-pyrazolo[1,5-a]azepin-3-yl]pyrimidin-2-amine | Human | 12647 | |||
| CDK6 | CDK | CMGC | 9pe7 | A | (3r,4r)-4-({(4m)-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1h-1,3-benzimidazol-6-yl]pyrimidin-2-yl}amino)-1-(methanesulfonyl)piperidin-3-ol | Human | 15858 | |||
| CDK6 | CDK | CMGC | 1jow | B | - | Human | 2793 | |||
| CDK6 | CDK | CMGC | 1bi8 | C | - | Human | 2799 | |||
| CDK6 | CDK | CMGC | 4ez5 | A | {5-[4-(dimethylamino)piperidin-1-yl]-1h-imidazo[4,5-b]pyridin-2-yl}[2-(isoquinolin-4-yl)pyridin-4-yl]methanone | Human | 2800 | |||
| CDK6 | CDK | CMGC | 2euf | B | 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 2804 | |||
| CDK6 | CDK | CMGC | 1xo2 | B | 3,7,3',4'-tetrahydroxyflavone | Human | 2794 | |||
| CDK6 | CDK | CMGC | 5l2s | A | n-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1h-benzimidazol-6-yl]pyrimidin-2-amine | Human | 6990 | |||
| CDK6 | CDK | CMGC | 1g3n | E | - | Human | 2805 | |||
| CDK6 | CDK | CMGC | 3nup | A | 4-[3-(1-methylethyl)-1h-pyrazol-4-yl]-n-(1-methylpiperidin-4-yl)pyrimidin-2-amine | Human | 2797 | |||
| CDK6 | CDK | CMGC | 4tth | B | 9-cyclopentyl-n-(5-piperazin-1-ylpyridin-2-yl)pyrido[4,5]pyrrolo[1,2-d]pyrimidin-2-amine | Human | 2803 | |||
| CDK6 | CDK | CMGC | 5l2i | A | 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 6991 |