Search results (17 entries covering 8 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
| ERBB2 (ErbB2) | EGFR | TK | 8u8x | A | B | 1-{(1r,3r,5s)-3-[(3m)-4-methyl-3-{3-methyl-4-[(1-methyl-1h-benzimidazol-5-yl)oxy]phenyl}-1h-pyrazolo[3,4-d]pyrimidin-1-yl]-8-azabicyclo[3.2.1]octan-8-yl}propan-1-one | Human | 15344 | ||
| ERBB2 (ErbB2) | EGFR | TK | 7jxh | A | B | (2e)-n-[3-cyano-7-ethoxy-4-({3-methyl-4-[([1,2,4]triazolo[1,5-a]pyridin-7-yl)oxy]phenyl}amino)quinolin-6-yl]-4-(dimethylamino)but-2-enamide | Human | 13887 | ||
| ERBB2 (ErbB2) | EGFR | TK | 7jxh | A | A | (2e)-n-[3-cyano-7-ethoxy-4-({3-methyl-4-[([1,2,4]triazolo[1,5-a]pyridin-7-yl)oxy]phenyl}amino)quinolin-6-yl]-4-(dimethylamino)but-2-enamide | Human | 13888 | ||
| ERBB2 (ErbB2) | EGFR | TK | 9qbf | A | - | Human | 16004 | |||
| ERBB2 (ErbB2) | EGFR | TK | 9qbh | A | - | Human | 16005 | |||
| ERBB2 (ErbB2) | EGFR | TK | 3rcd | B | - | Human | 9322 | |||
| ERBB2 (ErbB2) | EGFR | TK | 7pcd | A | A | 1-[4-[4-[[3,5-bis(chloranyl)-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]amino]pyrimido[5,4-d]pyrimidin-6-yl]piperazin-1-yl]-4-(3-fluoranylazetidin-1-yl)butan-1-one | Human | 14320 | ||
| ERBB2 (ErbB2) | EGFR | TK | 3rcd | D | - | Human | 9324 | |||
| ERBB2 (ErbB2) | EGFR | TK | 8u8x | A | A | 1-{(1r,3r,5s)-3-[(3m)-4-methyl-3-{3-methyl-4-[(1-methyl-1h-benzimidazol-5-yl)oxy]phenyl}-1h-pyrazolo[3,4-d]pyrimidin-1-yl]-8-azabicyclo[3.2.1]octan-8-yl}propan-1-one | Human | 15345 | ||
| ERBB2 (ErbB2) | EGFR | TK | 3rcd | C | n-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5h-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-3-hydroxy-3-methylbutanamide | Human | 9323 | |||
| ERBB2 (ErbB2) | EGFR | TK | 9qbg | A | - | Human | 16006 | |||
| ERBB2 (ErbB2) | EGFR | TK | 3pp0 | B | B | 2-{2-[4-({5-chloro-6-[3-(trifluoromethyl)phenoxy]pyridin-3-yl}amino)-5h-pyrrolo[3,2-d]pyrimidin-5-yl]ethoxy}ethanol | Human | 4819 | ||
| ERBB2 (ErbB2) | EGFR | TK | 7pcd | A | B | 1-[4-[4-[[3,5-bis(chloranyl)-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]amino]pyrimido[5,4-d]pyrimidin-6-yl]piperazin-1-yl]-4-(3-fluoranylazetidin-1-yl)butan-1-one | Human | 14319 | ||
| ERBB2 (ErbB2) | EGFR | TK | 3pp0 | A | A | 2-{2-[4-({5-chloro-6-[3-(trifluoromethyl)phenoxy]pyridin-3-yl}amino)-5h-pyrrolo[3,2-d]pyrimidin-5-yl]ethoxy}ethanol | Human | 4815 | ||
| ERBB2 (ErbB2) | EGFR | TK | 3pp0 | B | A | 2-{2-[4-({5-chloro-6-[3-(trifluoromethyl)phenoxy]pyridin-3-yl}amino)-5h-pyrrolo[3,2-d]pyrimidin-5-yl]ethoxy}ethanol | Human | 4816 | ||
| ERBB2 (ErbB2) | EGFR | TK | 3pp0 | A | B | 2-{2-[4-({5-chloro-6-[3-(trifluoromethyl)phenoxy]pyridin-3-yl}amino)-5h-pyrrolo[3,2-d]pyrimidin-5-yl]ethoxy}ethanol | Human | 4820 | ||
| ERBB2 (ErbB2) | EGFR | TK | 3rcd | A | n-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5h-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-3-hydroxy-3-methylbutanamide | Human | 9325 |