| FGFR1 | FGFR | TK | 7wcl | A | B | 11-[2,6-bis(fluoranyl)-3,5-dimethoxy-phenyl]-13-ethyl-4-(morpholin-4-ylmethyl)-5,7,11,13-tetrazatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),3,7-tetraen-12-one | Human | 14363 | |
| FGFR1 | FGFR | TK | 6itj | B | B | 4-azanyl-3-(3,5-dimethyl-1-benzofuran-2-yl)-2-phenyl-6~{h}-pyrazolo[3,4-d]pyridazin-7-one | Human | 11772 | |
| FGFR1 | FGFR | TK | 5flf | B | A | - | Human | 6465 | |
| FGFR1 | FGFR | TK | 5vnd | A | A | n-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-5-(4-ethylpiperazin-1-yl)phenyl}propanamide | Human | 7646 | |
| FGFR1 | FGFR | TK | 5ew8 | B | B | ~{n}'-(3,5-dimethoxyphenyl)-~{n}'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-~{n}-propan-2-yl-ethane-1,2-diamine | Human | 6471 | |
| FGFR1 | FGFR | TK | 5a46 | B | B | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | 3578 | |
| FGFR1 | FGFR | TK | 3c4f | B | B | 3-(3-methoxybenzyl)-1h-pyrrolo[2,3-b]pyridine | Human | 3562 | |
| FGFR1 | FGFR | TK | 4uwc | A | B | 3,4-dimethoxy-n-(5-phenyl-1h-pyrazol-3-yl)benzamide | Human | 6017 | |
| FGFR1 | FGFR | TK | 8jmz | A | A | n-(2-(dimethylamino)ethyl)-1-(3-((4-((2-methyl-1h-indol-5-yl)oxy)pyrimidin-2-yl)amino)phenyl)methanesulfonamide | Human | 15228 | |
| FGFR1 | FGFR | TK | 8jmz | A | B | n-(2-(dimethylamino)ethyl)-1-(3-((4-((2-methyl-1h-indol-5-yl)oxy)pyrimidin-2-yl)amino)phenyl)methanesulfonamide | Human | 15227 | |
| FGFR1 | FGFR | TK | 5uq0 | A | B | 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-carboxamide | Human | 7458 | |
| FGFR1 | FGFR | TK | 43xk | A | B | ~{n}-[[(2~{r},3~{s},4~{r},5~{r})-5-[4-azanyl-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-3,4-bis(oxidanyl)thiolan-2-yl]methyl]prop-2-enamide | Human | 15684 | |
| FGFR1 | FGFR | TK | 44ac | A | | ~{n}-[[(2~{r},3~{s},4~{r},5~{r})-5-[4-azanyl-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl]-2-fluoranyl-prop-2-enamide | Human | 15685 | |
| FGFR1 | FGFR | TK | 9wfk | A | B | (2~{r},3~{r},4~{s},5~{r})-2-[4-azanyl-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-5-(hydroxymethyl)oxolane-3,4-diol | Human | 15686 | |
| FGFR1 | FGFR | TK | 9wfk | A | A | (2~{r},3~{r},4~{s},5~{r})-2-[4-azanyl-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-5-(hydroxymethyl)oxolane-3,4-diol | Human | 15687 | |
| FGFR1 | FGFR | TK | 43zy | A | A | ~{n}-[[(2~{r},3~{s},4~{r},5~{r})-5-[4-azanyl-5-[2-(3,5-dimethoxyphenyl)ethynyl]pyrrolo[2,3-d]pyrimidin-7-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl]prop-2-enamide | Human | 15688 | |
| FGFR1 | FGFR | TK | 9w1a | A | | xs8148 | Human | 15679 | |
| FGFR1 | FGFR | TK | 43zy | A | B | ~{n}-[[(2~{r},3~{s},4~{r},5~{r})-5-[4-azanyl-5-[2-(3,5-dimethoxyphenyl)ethynyl]pyrrolo[2,3-d]pyrimidin-7-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl]prop-2-enamide | Human | 15680 | |
| FGFR1 | FGFR | TK | 44ah | A | A | derazantinib | Human | 15681 | |
| FGFR1 | FGFR | TK | 44ad | A | A | 2-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1~{h}-pyrazol-3-yl]-6-(4-methylpiperazin-1-yl)-1~{h}-benzimidazole | Human | 15682 | |
| FGFR1 | FGFR | TK | 44aa | A | A | (2~{r},3~{s},4~{r},5~{r})-2-[[(azanylidene-$l^{4}-azanylidene)amino]methyl]-5-[4-azanyl-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]oxolane-3,4-diol | Human | 15683 | |
| FGFR1 | FGFR | TK | 43zv | A | | ~{n}-[[(2~{r},3~{s},4~{r},5~{r})-5-[4-azanyl-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl]prop-2-enamide | Human | 15689 | |
| FGFR1 | FGFR | TK | 9wgt | A | A | (2~{r},3~{s},4~{r},5~{r})-2-(aminomethyl)-5-[4-azanyl-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]oxolane-3,4-diol | Human | 15690 | |
| FGFR1 | FGFR | TK | 9uhi | A | | ~{n}-[1-methyl-3-[3-[1-(2-morpholin-4-ylethyl)pyrazol-4-yl]quinoxalin-5-yl]indol-6-yl]propanamide | Human | 15691 | |
| FGFR1 | FGFR | TK | 9wgt | A | B | (2~{r},3~{s},4~{r},5~{r})-2-(aminomethyl)-5-[4-azanyl-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]oxolane-3,4-diol | Human | 15692 | |
| FGFR1 | FGFR | TK | 2fgi | B | | 1-tert-butyl-3-[6-(3,5-dimethoxy-phenyl)-2-(4-diethylamino-butylamino)-pyrido[2,3-d]pyrimidin-7-yl]-urea | Human | 3541 | |
| FGFR1 | FGFR | TK | 3gql | B | | (e)-[4-(3,5-difluorophenyl)-3h-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol | Human | 3506 | |
| FGFR1 | FGFR | TK | 5ur1 | B | A | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{1-[4-(dimethylamino)but-2-enoyl]piperidin-4-yl}-7-(phenylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 7969 | |
| FGFR1 | FGFR | TK | 1fgk | B | B | - | Human | 3557 | |
| FGFR1 | FGFR | TK | 5am7 | A | B | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | 3488 | |
| FGFR1 | FGFR | TK | 5flf | D | A | - | Human | 6468 | |
| FGFR1 | FGFR | TK | 5uq0 | A | A | 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-carboxamide | Human | 7456 | |
| FGFR1 | FGFR | TK | 4rwl | B | | 6-({7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl}oxy)-n-methylnaphthalene-1-carboxamide | Human | 3596 | |
| FGFR1 | FGFR | TK | 6mzw | B | A | 1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one | Human | 11165 | |
| FGFR1 | FGFR | TK | 3rhx | B | | (6s)-6-phenyl-5,6-dihydrobenzo[h]quinazolin-2-amine | Human | 3522 | |
| FGFR1 | FGFR | TK | 4zsa | A | A | 4-(4-ethylpiperazin-1-yl)-n-[6-(3-methoxyphenyl)-2h-indazol-3-yl]benzamide | Human | 3491 | |
| FGFR1 | FGFR | TK | 6c1b | B | B | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3s)-1-[(2e)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-7-(phenylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 11167 | |
| FGFR1 | FGFR | TK | 4rwj | B | B | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3559 | |
| FGFR1 | FGFR | TK | 4v05 | A | B | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3593 | |
| FGFR1 | FGFR | TK | 5z0s | B | B | 1-[(6-chloroimidazo[1,2-b]pyridazin-3-yl)sulfonyl]-6-(1-methyl-1h-pyrazol-4-yl)-1h-pyrazolo[4,3-b]pyridine | Human | 10814 | |
| FGFR1 | FGFR | TK | 44ad | A | B | 2-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1~{h}-pyrazol-3-yl]-6-(4-methylpiperazin-1-yl)-1~{h}-benzimidazole | Human | 15672 | |
| FGFR1 | FGFR | TK | 3tt0 | B | A | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1-methylurea | Human | 3547 | |
| FGFR1 | FGFR | TK | 1agw | B | B | 3-[4-(1-formylpiperazin-4-yl)-benzylidenyl]-2-indolinone | Human | 3510 | |
| FGFR1 | FGFR | TK | 8jqi | B | | - | Human | 15678 | |
| FGFR1 | FGFR | TK | 5vnd | B | A | n-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-5-(4-ethylpiperazin-1-yl)phenyl}propanamide | Human | 7647 | |
| FGFR1 | FGFR | TK | 7ozd | A | A | n-[6-(4-hydroxyphenyl)-1h-indazol-3-yl]benzamide | Human | 14007 | |
| FGFR1 | FGFR | TK | 5am7 | A | A | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | 3533 | |
| FGFR1 | FGFR | TK | 6mzq | B | B | 1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one | Human | 11171 | |
| FGFR1 | FGFR | TK | 6nvl | D | B | n-[2-({5-[(2,6-dichloro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl}amino)-3-methylphenyl]propanamide | Human | 11398 | |
| FGFR1 | FGFR | TK | 6p69 | B | A | n-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl][3-(4-methylpiperazin-1-yl)propyl]amino}pyrimidin-4-yl)amino]phenyl}prop-2-enamide | Human | 11331 | |
| FGFR1 | FGFR | TK | 5zv2 | B | | 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide | Human | 10054 | |
| FGFR1 | FGFR | TK | 4v04 | A | A | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | 3542 | |
| FGFR1 | FGFR | TK | 4uwy | A | B | - | Human | 3582 | |
| FGFR1 | FGFR | TK | 5a46 | B | A | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | 3526 | |
| FGFR1 | FGFR | TK | 4f65 | B | A | 5-bromo-n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]-n~4~-[3-(2-phenylethyl)-1h-pyrazol-5-yl]pyrimidine-2,4-diamine | Human | 3545 | |
| FGFR1 | FGFR | TK | 1fgk | B | A | - | Human | 3513 | |
| FGFR1 | FGFR | TK | 6c18 | A | B | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3s)-1-[(2e)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-7-[(propan-2-yl)amino]-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 11168 | |
| FGFR1 | FGFR | TK | 1agw | A | A | 3-[4-(1-formylpiperazin-4-yl)-benzylidenyl]-2-indolinone | Human | 3520 | |
| FGFR1 | FGFR | TK | 5a4c | A | A | 1-tert-butyl-3-[2-[3-(diethylamino)propylamino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea | Human | 3543 | |
| FGFR1 | FGFR | TK | 4nk9 | B | | n~4~-{5-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-3-yl}-n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine | Human | 3535 | |
| FGFR1 | FGFR | TK | 7ozb | A | B | 4-[3-(4-piperazin-4-ium-1-ylphenyl)-1h-indazol-6-yl]phenol | Human | 14008 | |
| FGFR1 | FGFR | TK | 5ur1 | B | B | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{1-[4-(dimethylamino)but-2-enoyl]piperidin-4-yl}-7-(phenylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 7971 | |
| FGFR1 | FGFR | TK | 4uwy | B | A | - | Human | 3537 | |
| FGFR1 | FGFR | TK | 4f64 | B | A | 5-bromo-n~4~-[3-(3-methoxypropyl)-1h-pyrazol-5-yl]-n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine | Human | 3576 | |
| FGFR1 | FGFR | TK | 4rwk | A | B | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3517 | |
| FGFR1 | FGFR | TK | 1fgi | A | A | 3-[(3-(2-carboxyethyl)-4-methylpyrrol-2-yl)methylene]-2-indolinone | Human | 3555 | |
| FGFR1 | FGFR | TK | 3c4f | A | A | 3-(3-methoxybenzyl)-1h-pyrrolo[2,3-b]pyridine | Human | 3515 | |
| FGFR1 | FGFR | TK | 5uq0 | B | A | 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-carboxamide | Human | 7459 | |
| FGFR1 | FGFR | TK | 6c19 | A | A | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3s)-1-[(2e)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-7-(methylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 11163 | |
| FGFR1 | FGFR | TK | 3ky2 | A | | - | Human | 3534 | |
| FGFR1 | FGFR | TK | 5am6 | B | B | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | 3521 | |
| FGFR1 | FGFR | TK | 5o4a | A | A | [(2~{r},3~{s},4~{r},5~{r})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl 4-ethyl-3-fluorosulfonyl-benzoate | Human | 9554 | |
| FGFR1 | FGFR | TK | 4rwi | B | B | - | Human | 3527 | |
| FGFR1 | FGFR | TK | 5flf | C | B | - | Human | 6466 | |
| FGFR1 | FGFR | TK | 5a4c | B | B | 1-tert-butyl-3-[2-[3-(diethylamino)propylamino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea | Human | 3540 | |
| FGFR1 | FGFR | TK | 5o4a | A | B | [(2~{r},3~{s},4~{r},5~{r})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl 4-ethyl-3-fluorosulfonyl-benzoate | Human | 9558 | |
| FGFR1 | FGFR | TK | 6c1o | A | A | n-(3-{[3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-{[4-(diethylamino)butyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2h)-yl]methyl}phenyl)prop-2-enamide | Human | 11159 | |
| FGFR1 | FGFR | TK | 5b7v | A | | [5-amino-1-(2-methyl-1h-benzimidazol-6-yl)-1h-pyrazol-4-yl](1h-indol-2-yl)methanone | Human | 6705 | |
| FGFR1 | FGFR | TK | 4nka | A | | n~4~-{3-[2-(3,4-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine | Human | 3501 | |
| FGFR1 | FGFR | TK | 4zsa | B | B | 4-(4-ethylpiperazin-1-yl)-n-[6-(3-methoxyphenyl)-2h-indazol-3-yl]benzamide | Human | 3512 | |
| FGFR1 | FGFR | TK | 6mzw | A | B | 1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one | Human | 11157 | |
| FGFR1 | FGFR | TK | 6mzq | A | B | 1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one | Human | 11156 | |
| FGFR1 | FGFR | TK | 6itj | B | A | 4-azanyl-3-(3,5-dimethyl-1-benzofuran-2-yl)-2-phenyl-6~{h}-pyrazolo[3,4-d]pyridazin-7-one | Human | 11775 | |
| FGFR1 | FGFR | TK | 4f64 | A | B | 5-bromo-n~4~-[3-(3-methoxypropyl)-1h-pyrazol-5-yl]-n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine | Human | 3589 | |
| FGFR1 | FGFR | TK | 4uwc | A | A | 3,4-dimethoxy-n-(5-phenyl-1h-pyrazol-3-yl)benzamide | Human | 6019 | |
| FGFR1 | FGFR | TK | 3tt0 | B | B | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1-methylurea | Human | 3581 | |
| FGFR1 | FGFR | TK | 4rwl | A | | - | Human | 3516 | |
| FGFR1 | FGFR | TK | 3c4f | A | B | 3-(3-methoxybenzyl)-1h-pyrrolo[2,3-b]pyridine | Human | 3564 | |
| FGFR1 | FGFR | TK | 5am6 | A | A | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | 3494 | |
| FGFR1 | FGFR | TK | 6mzw | B | B | 1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one | Human | 10857 | |
| FGFR1 | FGFR | TK | 5am7 | B | B | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | 3531 | |
| FGFR1 | FGFR | TK | 6itj | A | A | 4-azanyl-3-(3,5-dimethyl-1-benzofuran-2-yl)-2-phenyl-6~{h}-pyrazolo[3,4-d]pyridazin-7-one | Human | 11773 | |
| FGFR1 | FGFR | TK | 6c19 | A | B | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3s)-1-[(2e)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-7-(methylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 10859 | |
| FGFR1 | FGFR | TK | 5flf | C | A | - | Human | 6469 | |
| FGFR1 | FGFR | TK | 6nvl | B | A | n-[2-({5-[(2,6-dichloro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl}amino)-3-methylphenyl]propanamide | Human | 11403 | |
| FGFR1 | FGFR | TK | 7ozb | A | A | 4-[3-(4-piperazin-4-ium-1-ylphenyl)-1h-indazol-6-yl]phenol | Human | 14010 | |
| FGFR1 | FGFR | TK | 5ur1 | A | A | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{1-[4-(dimethylamino)but-2-enoyl]piperidin-4-yl}-7-(phenylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 7970 | |
| FGFR1 | FGFR | TK | 6c1b | A | A | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3s)-1-[(2e)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-7-(phenylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 11169 | |
| FGFR1 | FGFR | TK | 3gqi | A | | phosphomethylphosphonic acid adenylate ester | Human | 3566 | |
| FGFR1 | FGFR | TK | 4v05 | B | A | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3518 | |
| FGFR1 | FGFR | TK | 7ozf | A | A | n-[6-(3-ethoxyphenyl)-1h-indazol-3-yl]benzamide | Human | 14011 | |
| FGFR1 | FGFR | TK | 4rwi | A | B | - | Human | 3551 | |
| FGFR1 | FGFR | TK | 6nvl | A | B | n-[2-({5-[(2,6-dichloro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl}amino)-3-methylphenyl]propanamide | Human | 11401 | |
| FGFR1 | FGFR | TK | 3gql | A | | (e)-[4-(3,5-difluorophenyl)-3h-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol | Human | 3509 | |
| FGFR1 | FGFR | TK | 6c19 | B | A | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3s)-1-[(2e)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-7-(methylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 10855 | |
| FGFR1 | FGFR | TK | 6c1b | A | B | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3s)-1-[(2e)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-7-(phenylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 10861 | |
| FGFR1 | FGFR | TK | 6p69 | A | B | n-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl][3-(4-methylpiperazin-1-yl)propyl]amino}pyrimidin-4-yl)amino]phenyl}prop-2-enamide | Human | 11330 | |
| FGFR1 | FGFR | TK | 4v01 | A | B | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | 3590 | |
| FGFR1 | FGFR | TK | 6nvl | C | A | n-[2-({5-[(2,6-dichloro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl}amino)-3-methylphenyl]propanamide | Human | 11404 | |
| FGFR1 | FGFR | TK | 4wun | A | B | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3595 | |
| FGFR1 | FGFR | TK | 4nks | B | A | n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]-n~4~-[5-(2-phenylethyl)-1h-pyrazol-3-yl]pyrimidine-2,4-diamine | Human | 3492 | |
| FGFR1 | FGFR | TK | 3kxx | D | | - | Human | 3503 | |
| FGFR1 | FGFR | TK | 44aa | A | B | (2~{r},3~{s},4~{r},5~{r})-2-[[(azanylidene-$l^{4}-azanylidene)amino]methyl]-5-[4-azanyl-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]oxolane-3,4-diol | Human | 15671 | |
| FGFR1 | FGFR | TK | 5o4a | B | B | [(2~{r},3~{s},4~{r},5~{r})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl 4-ethyl-3-fluorosulfonyl-benzoate | Human | 9555 | |
| FGFR1 | FGFR | TK | 5z0s | B | A | 1-[(6-chloroimidazo[1,2-b]pyridazin-3-yl)sulfonyl]-6-(1-methyl-1h-pyrazol-4-yl)-1h-pyrazolo[4,3-b]pyridine | Human | 10812 | |
| FGFR1 | FGFR | TK | 6nvl | A | A | n-[2-({5-[(2,6-dichloro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl}amino)-3-methylphenyl]propanamide | Human | 11400 | |
| FGFR1 | FGFR | TK | 5b7v | B | | [5-amino-1-(2-methyl-1h-benzimidazol-6-yl)-1h-pyrazol-4-yl](1h-indol-2-yl)methanone | Human | 6704 | |
| FGFR1 | FGFR | TK | 7ozf | A | B | n-[6-(3-ethoxyphenyl)-1h-indazol-3-yl]benzamide | Human | 14006 | |
| FGFR1 | FGFR | TK | 4v05 | B | B | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3493 | |
| FGFR1 | FGFR | TK | 4v01 | A | A | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | 3556 | |
| FGFR1 | FGFR | TK | 5am7 | B | A | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | 3588 | |
| FGFR1 | FGFR | TK | 5flf | B | B | - | Human | 6467 | |
| FGFR1 | FGFR | TK | 6p68 | A | | n-{3-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-1-(2-hydroxyethyl)-1h-pyrazol-4-yl}prop-2-enamide | Human | 11336 | |
| FGFR1 | FGFR | TK | 5flf | E | A | - | Human | 6473 | |
| FGFR1 | FGFR | TK | 4rwk | A | A | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3500 | |
| FGFR1 | FGFR | TK | 5am6 | B | A | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | 3587 | |
| FGFR1 | FGFR | TK | 6mzq | A | A | 1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one | Human | 10860 | |
| FGFR1 | FGFR | TK | 3js2 | B | | 5-(2-thienyl)nicotinic acid | Human | 3504 | |
| FGFR1 | FGFR | TK | 5o49 | B | B | [(2~{r},3~{s},4~{r},5~{r})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl 3-fluorosulfonylbenzoate | Human | 9557 | |
| FGFR1 | FGFR | TK | 6p68 | C | | n-{3-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-1-(2-hydroxyethyl)-1h-pyrazol-4-yl}prop-2-enamide | Human | 11332 | |
| FGFR1 | FGFR | TK | 4rwk | B | A | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3591 | |
| FGFR1 | FGFR | TK | 5ew8 | B | A | ~{n}'-(3,5-dimethoxyphenyl)-~{n}'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-~{n}-propan-2-yl-ethane-1,2-diamine | Human | 6474 | |
| FGFR1 | FGFR | TK | 5am6 | A | B | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | 3514 | |
| FGFR1 | FGFR | TK | 5o49 | A | A | [(2~{r},3~{s},4~{r},5~{r})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl 3-fluorosulfonylbenzoate | Human | 9560 | |
| FGFR1 | FGFR | TK | 4f65 | A | A | 5-bromo-n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]-n~4~-[3-(2-phenylethyl)-1h-pyrazol-5-yl]pyrimidine-2,4-diamine | Human | 3558 | |
| FGFR1 | FGFR | TK | 4nk9 | A | | n~4~-{5-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-3-yl}-n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine | Human | 3550 | |
| FGFR1 | FGFR | TK | 5flf | A | A | - | Human | 6462 | |
| FGFR1 | FGFR | TK | 9vlj | A | | ~{n}-[3-[2-[[3-[2-(dimethylamino)ethylsulfamoylmethyl]phenyl]amino]pyrimidin-4-yl]-1-methyl-indol-6-yl]propanamide | Human | 15673 | |
| FGFR1 | FGFR | TK | 3kxx | B | | - | Human | 3575 | |
| FGFR1 | FGFR | TK | 5o4a | B | A | [(2~{r},3~{s},4~{r},5~{r})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl 4-ethyl-3-fluorosulfonyl-benzoate | Human | 9559 | |
| FGFR1 | FGFR | TK | 4uwb | A | B | n-[4-(4-methylpiperazin-1-yl)phenyl]-1h-indazole-3-carboxamide | Human | 6023 | |
| FGFR1 | FGFR | TK | 43xk | A | A | ~{n}-[[(2~{r},3~{s},4~{r},5~{r})-5-[4-azanyl-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-3,4-bis(oxidanyl)thiolan-2-yl]methyl]prop-2-enamide | Human | 15674 | |
| FGFR1 | FGFR | TK | 1fgk | A | A | - | Human | 3592 | |
| FGFR1 | FGFR | TK | 6nvl | B | B | n-[2-({5-[(2,6-dichloro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl}amino)-3-methylphenyl]propanamide | Human | 11399 | |
| FGFR1 | FGFR | TK | 6mzq | B | A | 1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one | Human | 11161 | |
| FGFR1 | FGFR | TK | 6c19 | B | B | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3s)-1-[(2e)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-7-(methylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 10862 | |
| FGFR1 | FGFR | TK | 9u7g | A | | (e)-4-methyl-17-(1-methyl-1h-pyrazol-4-yl)-7,10-dioxa-4-aza-1(3,6)-imidazo[1,2-b]pyridazina-2(3,5)-pyridinacyclodecaphan-3-one | Human | 15675 | |
| FGFR1 | FGFR | TK | 5a4c | A | B | 1-tert-butyl-3-[2-[3-(diethylamino)propylamino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea | Human | 3498 | |
| FGFR1 | FGFR | TK | 6c1o | B | A | n-(3-{[3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-{[4-(diethylamino)butyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2h)-yl]methyl}phenyl)prop-2-enamide | Human | 11160 | |
| FGFR1 | FGFR | TK | 1fgi | B | A | 3-[(3-(2-carboxyethyl)-4-methylpyrrol-2-yl)methylene]-2-indolinone | Human | 3586 | |
| FGFR1 | FGFR | TK | 6c1c | B | B | 7-(cyclohexylamino)-3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3s)-1-[(2e)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 11158 | |
| FGFR1 | FGFR | TK | 6c18 | B | A | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3s)-1-[(2e)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-7-[(propan-2-yl)amino]-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 10854 | |
| FGFR1 | FGFR | TK | 9uhc | A | | ~{n}-[1-methyl-3-[2-[1-(2-morpholin-4-ylethyl)pyrazol-4-yl]-5~{h}-pyrrolo[2,3-b]pyrazin-7-yl]indol-6-yl]propanamide | Human | 15676 | |
| FGFR1 | FGFR | TK | 44ah | A | B | derazantinib | Human | 15677 | |
| FGFR1 | FGFR | TK | 6c1c | A | A | 7-(cyclohexylamino)-3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3s)-1-[(2e)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 11164 | |
| FGFR1 | FGFR | TK | 5ew8 | A | A | ~{n}'-(3,5-dimethoxyphenyl)-~{n}'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-~{n}-propan-2-yl-ethane-1,2-diamine | Human | 6470 | |
| FGFR1 | FGFR | TK | 4f64 | B | B | 5-bromo-n~4~-[3-(3-methoxypropyl)-1h-pyrazol-5-yl]-n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine | Human | 3553 | |
| FGFR1 | FGFR | TK | 5zv2 | A | | 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide | Human | 10055 | |
| FGFR1 | FGFR | TK | 5o49 | A | B | [(2~{r},3~{s},4~{r},5~{r})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl 3-fluorosulfonylbenzoate | Human | 9556 | |
| FGFR1 | FGFR | TK | 4f63 | B | | 5-bromo-n~4~-(3-methyl-1h-pyrazol-5-yl)-n~2~-[2-(pyridin-3-yl)ethyl]pyrimidine-2,4-diamine | Human | 3574 | |
| FGFR1 | FGFR | TK | 3tt0 | A | A | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1-methylurea | Human | 3567 | |
| FGFR1 | FGFR | TK | 5o49 | B | A | [(2~{r},3~{s},4~{r},5~{r})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl 3-fluorosulfonylbenzoate | Human | 9561 | |
| FGFR1 | FGFR | TK | 4wun | B | A | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3529 | |
| FGFR1 | FGFR | TK | 1fgi | A | B | 3-[(3-(2-carboxyethyl)-4-methylpyrrol-2-yl)methylene]-2-indolinone | Human | 3552 | |
| FGFR1 | FGFR | TK | 4f64 | A | A | 5-bromo-n~4~-[3-(3-methoxypropyl)-1h-pyrazol-5-yl]-n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine | Human | 3548 | |
| FGFR1 | FGFR | TK | 6c1o | B | B | n-(3-{[3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-{[4-(diethylamino)butyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2h)-yl]methyl}phenyl)prop-2-enamide | Human | 11154 | |
| FGFR1 | FGFR | TK | 5vnd | B | B | n-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-5-(4-ethylpiperazin-1-yl)phenyl}propanamide | Human | 7645 | |
| FGFR1 | FGFR | TK | 4uwb | B | A | n-[4-(4-methylpiperazin-1-yl)phenyl]-1h-indazole-3-carboxamide | Human | 6018 | |
| FGFR1 | FGFR | TK | 4f63 | A | | 5-bromo-n~4~-(3-methyl-1h-pyrazol-5-yl)-n~2~-[2-(pyridin-3-yl)ethyl]pyrimidine-2,4-diamine | Human | 3563 | |
| FGFR1 | FGFR | TK | 3js2 | A | | 5-(2-thienyl)nicotinic acid | Human | 3523 | |
| FGFR1 | FGFR | TK | 1agw | A | B | 3-[4-(1-formylpiperazin-4-yl)-benzylidenyl]-2-indolinone | Human | 3528 | |
| FGFR1 | FGFR | TK | 6mzw | A | A | 1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one | Human | 11162 | |
| FGFR1 | FGFR | TK | 1fgk | A | B | - | Human | 3546 | |
| FGFR1 | FGFR | TK | 4v04 | A | B | - | Human | 3571 | |
| FGFR1 | FGFR | TK | 4uwy | A | A | - | Human | 3489 | |
| FGFR1 | FGFR | TK | 6nvl | C | B | n-[2-({5-[(2,6-dichloro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl}amino)-3-methylphenyl]propanamide | Human | 11405 | |
| FGFR1 | FGFR | TK | 3ky2 | B | | - | Human | 3525 | |
| FGFR1 | FGFR | TK | 6p68 | B | | n-{3-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-1-(2-hydroxyethyl)-1h-pyrazol-4-yl}prop-2-enamide | Human | 11334 | |
| FGFR1 | FGFR | TK | 4rwj | A | B | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3519 | |
| FGFR1 | FGFR | TK | 5flf | E | B | - | Human | 6472 | |
| FGFR1 | FGFR | TK | 3c4f | B | A | 3-(3-methoxybenzyl)-1h-pyrrolo[2,3-b]pyridine | Human | 3573 | |
| FGFR1 | FGFR | TK | 4rwj | A | A | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3584 | |
| FGFR1 | FGFR | TK | 6c1b | B | A | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3s)-1-[(2e)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-7-(phenylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 10856 | |
| FGFR1 | FGFR | TK | 4rwk | B | B | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3530 | |
| FGFR1 | FGFR | TK | 4zsa | A | B | 4-(4-ethylpiperazin-1-yl)-n-[6-(3-methoxyphenyl)-2h-indazol-3-yl]benzamide | Human | 3487 | |
| FGFR1 | FGFR | TK | 4v01 | B | A | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | 3497 | |
| FGFR1 | FGFR | TK | 4uwb | B | B | n-[4-(4-methylpiperazin-1-yl)phenyl]-1h-indazole-3-carboxamide | Human | 6022 | |
| FGFR1 | FGFR | TK | 3tt0 | A | B | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1-methylurea | Human | 3538 | |
| FGFR1 | FGFR | TK | 4nks | A | A | n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]-n~4~-[5-(2-phenylethyl)-1h-pyrazol-3-yl]pyrimidine-2,4-diamine | Human | 3570 | |
| FGFR1 | FGFR | TK | 4nks | B | B | n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]-n~4~-[5-(2-phenylethyl)-1h-pyrazol-3-yl]pyrimidine-2,4-diamine | Human | 3577 | |
| FGFR1 | FGFR | TK | 4uwc | B | A | 3,4-dimethoxy-n-(5-phenyl-1h-pyrazol-3-yl)benzamide | Human | 6021 | |
| FGFR1 | FGFR | TK | 4rwj | B | A | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3579 | |
| FGFR1 | FGFR | TK | 4zsa | B | A | 4-(4-ethylpiperazin-1-yl)-n-[6-(3-methoxyphenyl)-2h-indazol-3-yl]benzamide | Human | 3572 | |
| FGFR1 | FGFR | TK | 3kxx | A | | - | Human | 3495 | |
| FGFR1 | FGFR | TK | 4v04 | B | B | - | Human | 3496 | |
| FGFR1 | FGFR | TK | 1agw | B | A | 3-[4-(1-formylpiperazin-4-yl)-benzylidenyl]-2-indolinone | Human | 3568 | |
| FGFR1 | FGFR | TK | 4nks | A | B | n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]-n~4~-[5-(2-phenylethyl)-1h-pyrazol-3-yl]pyrimidine-2,4-diamine | Human | 3561 | |
| FGFR1 | FGFR | TK | 5a4c | B | A | 1-tert-butyl-3-[2-[3-(diethylamino)propylamino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea | Human | 3585 | |
| FGFR1 | FGFR | TK | 5vnd | A | B | n-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-5-(4-ethylpiperazin-1-yl)phenyl}propanamide | Human | 7648 | |
| FGFR1 | FGFR | TK | 5z0s | A | A | 1-[(6-chloroimidazo[1,2-b]pyridazin-3-yl)sulfonyl]-6-(1-methyl-1h-pyrazol-4-yl)-1h-pyrazolo[4,3-b]pyridine | Human | 10813 | |
| FGFR1 | FGFR | TK | 6c18 | B | B | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3s)-1-[(2e)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-7-[(propan-2-yl)amino]-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 11170 | |
| FGFR1 | FGFR | TK | 5flf | A | B | - | Human | 6464 | |
| FGFR1 | FGFR | TK | 5z0s | A | B | 1-[(6-chloroimidazo[1,2-b]pyridazin-3-yl)sulfonyl]-6-(1-methyl-1h-pyrazol-4-yl)-1h-pyrazolo[4,3-b]pyridine | Human | 10815 | |
| FGFR1 | FGFR | TK | 4nka | B | | n~4~-{3-[2-(3,4-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine | Human | 3539 | |
| FGFR1 | FGFR | TK | 4uwb | A | A | n-[4-(4-methylpiperazin-1-yl)phenyl]-1h-indazole-3-carboxamide | Human | 6020 | |
| FGFR1 | FGFR | TK | 5a46 | A | A | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | 3532 | |
| FGFR1 | FGFR | TK | 6c1o | A | B | n-(3-{[3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-{[4-(diethylamino)butyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2h)-yl]methyl}phenyl)prop-2-enamide | Human | 11166 | |
| FGFR1 | FGFR | TK | 3kxx | C | | - | Human | 3549 | |
| FGFR1 | FGFR | TK | 2fgi | A | | 1-tert-butyl-3-[6-(3,5-dimethoxy-phenyl)-2-(4-diethylamino-butylamino)-pyrido[2,3-d]pyrimidin-7-yl]-urea | Human | 3490 | |
| FGFR1 | FGFR | TK | 7ozd | A | B | n-[6-(4-hydroxyphenyl)-1h-indazol-3-yl]benzamide | Human | 14009 | |
| FGFR1 | FGFR | TK | 3gql | C | | (e)-[4-(3,5-difluorophenyl)-3h-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol | Human | 3536 | |
| FGFR1 | FGFR | TK | 5ur1 | A | B | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{1-[4-(dimethylamino)but-2-enoyl]piperidin-4-yl}-7-(phenylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 7972 | |
| FGFR1 | FGFR | TK | 1fgi | B | B | 3-[(3-(2-carboxyethyl)-4-methylpyrrol-2-yl)methylene]-2-indolinone | Human | 3580 | |
| FGFR1 | FGFR | TK | 4rwi | A | A | - | Human | 3499 | |
| FGFR1 | FGFR | TK | 6c1c | B | A | 7-(cyclohexylamino)-3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3s)-1-[(2e)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 10858 | |
| FGFR1 | FGFR | TK | 6p69 | A | A | n-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl][3-(4-methylpiperazin-1-yl)propyl]amino}pyrimidin-4-yl)amino]phenyl}prop-2-enamide | Human | 11333 | |
| FGFR1 | FGFR | TK | 6p69 | B | B | n-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl][3-(4-methylpiperazin-1-yl)propyl]amino}pyrimidin-4-yl)amino]phenyl}prop-2-enamide | Human | 11335 | |
| FGFR1 | FGFR | TK | 4v04 | B | A | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | 3524 | |
| FGFR1 | FGFR | TK | 4v05 | A | A | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3560 | |
| FGFR1 | FGFR | TK | 4uwy | B | B | - | Human | 3583 | |
| FGFR1 | FGFR | TK | 5uq0 | B | B | 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-carboxamide | Human | 7457 | |
| FGFR1 | FGFR | TK | 4uwc | B | B | 3,4-dimethoxy-n-(5-phenyl-1h-pyrazol-3-yl)benzamide | Human | 6016 | |
| FGFR1 | FGFR | TK | 6c18 | A | A | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3s)-1-[(2e)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-7-[(propan-2-yl)amino]-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 11155 | |
| FGFR1 | FGFR | TK | 4v01 | B | B | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | 3594 | |
| FGFR1 | FGFR | TK | 4f65 | B | B | 5-bromo-n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]-n~4~-[3-(2-phenylethyl)-1h-pyrazol-5-yl]pyrimidine-2,4-diamine | Human | 3502 | |
| FGFR1 | FGFR | TK | 7wcl | A | A | 11-[2,6-bis(fluoranyl)-3,5-dimethoxy-phenyl]-13-ethyl-4-(morpholin-4-ylmethyl)-5,7,11,13-tetrazatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),3,7-tetraen-12-one | Human | 14364 | |
| FGFR1 | FGFR | TK | 5a46 | A | B | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]quinolin-2(1h)-one | Human | 3505 | |
| FGFR1 | FGFR | TK | 6c1c | A | B | 7-(cyclohexylamino)-3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3s)-1-[(2e)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 10853 | |
| FGFR1 | FGFR | TK | 4wun | A | A | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3511 | |
| FGFR1 | FGFR | TK | 6itj | A | B | 4-azanyl-3-(3,5-dimethyl-1-benzofuran-2-yl)-2-phenyl-6~{h}-pyrazolo[3,4-d]pyridazin-7-one | Human | 11774 | |
| FGFR1 | FGFR | TK | 6nvl | D | A | n-[2-({5-[(2,6-dichloro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl}amino)-3-methylphenyl]propanamide | Human | 11402 | |
| FGFR1 | FGFR | TK | 3rhx | A | | (6s)-6-phenyl-5,6-dihydrobenzo[h]quinazolin-2-amine | Human | 3554 | |
| FGFR1 | FGFR | TK | 5ew8 | A | B | ~{n}'-(3,5-dimethoxyphenyl)-~{n}'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-~{n}-propan-2-yl-ethane-1,2-diamine | Human | 6461 | |
| FGFR1 | FGFR | TK | 4rwi | B | A | - | Human | 3569 | |
| FGFR1 | FGFR | TK | 5flf | D | B | - | Human | 6463 | |
| FGFR1 | FGFR | TK | 4f65 | A | B | 5-bromo-n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]-n~4~-[3-(2-phenylethyl)-1h-pyrazol-5-yl]pyrimidine-2,4-diamine | Human | 3508 | |
| FGFR1 | FGFR | TK | 4wun | B | B | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3565 | |
