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Search results (125 entries covering 43 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetails File
FGFR2FGFRTK2pvyCphosphomethylphosphonic acid adenylate esterHuman501
FGFR2FGFRTK8e1xA(5m)-n-methyl-5-{(6m,8s)-5-{[(3s)-oxolan-3-yl]amino}-6-[1-(propan-2-yl)-1h-pyrazol-3-yl]pyrazolo[1,5-a]pyrimidin-3-yl}pyridine-3-carboxamideHuman14511
FGFR2FGFRTK7kieBAn-{4-[(e)-2-{4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}ethenyl]phenyl}prop-2-enamideHuman13282
FGFR2FGFRTK6agxCBethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5h-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1h-imidazol-1-yl]acetateHuman11537
FGFR2FGFRTK6agxABethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5h-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1h-imidazol-1-yl]acetateHuman11542
FGFR2FGFRTK4j95DAphosphomethylphosphonic acid adenylate esterHuman490
FGFR2FGFRTK4j97DBphosphomethylphosphonic acid adenylate esterHuman532
FGFR2FGFRTK4j95BBphosphomethylphosphonic acid adenylate esterHuman519
FGFR2FGFRTK4j96AB-Human470
FGFR2FGFRTK6agxCAethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5h-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1h-imidazol-1-yl]acetateHuman11538
FGFR2FGFRTK4j95ABphosphomethylphosphonic acid adenylate esterHuman477
FGFR2FGFRTK5ugxABphosphomethylphosphonic acid adenylate esterHuman7448
FGFR2FGFRTK7kiaAB1-[4-(4-{4-(4-methylpiperazin-1-yl)-6-[(3-methyl-1h-pyrazol-5-yl)amino]pyrimidin-2-yl}phenyl)piperidin-1-yl]prop-2-en-1-oneHuman13285
FGFR2FGFRTK6v6qCphosphomethylphosphonic acid adenylate esterHuman12969
FGFR2FGFRTK6lvlAn-ethyl-2-[[4-[[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulfonamideHuman12132
FGFR2FGFRTK6lvlBn-ethyl-2-[[4-[[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulfonamideHuman12130
FGFR2FGFRTK4j97BAphosphomethylphosphonic acid adenylate esterHuman476
FGFR2FGFRTK6agxBAethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5h-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1h-imidazol-1-yl]acetateHuman11540
FGFR2FGFRTK4j95BAphosphomethylphosphonic acid adenylate esterHuman498
FGFR2FGFRTK4j95CAphosphomethylphosphonic acid adenylate esterHuman531
FGFR2FGFRTK2pwlAphosphomethylphosphonic acid adenylate esterHuman523
FGFR2FGFRTK4j98BBphosphomethylphosphonic acid adenylate esterHuman472
FGFR2FGFRTK8w38AB1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-oneHuman15403
FGFR2FGFRTK6agxBBethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5h-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1h-imidazol-1-yl]acetateHuman11536
FGFR2FGFRTK4j97CAphosphomethylphosphonic acid adenylate esterHuman488
FGFR2FGFRTK6lvkBn-ethyl-2-[[4-[[4-(4-methylpiperazin-1-yl)-3-(2-morpholin-4-ylethoxy)phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulfonamideHuman12129
FGFR2FGFRTK5uglBAphosphoaminophosphonic acid-adenylate esterHuman7450
FGFR2FGFRTK6v6qBphosphomethylphosphonic acid adenylate esterHuman12966
FGFR2FGFRTK4j99DBphosphomethylphosphonic acid adenylate esterHuman481
FGFR2FGFRTK4j95AAphosphomethylphosphonic acid adenylate esterHuman529
FGFR2FGFRTK4j97BCphosphomethylphosphonic acid adenylate esterHuman510
FGFR2FGFRTK4j97CCphosphomethylphosphonic acid adenylate esterHuman483
FGFR2FGFRTK5uhnBAphosphomethylphosphonic acid adenylate esterHuman7451
FGFR2FGFRTK5ugxBBphosphomethylphosphonic acid adenylate esterHuman7445
FGFR2FGFRTK6v6qAphosphomethylphosphonic acid adenylate esterHuman12968
FGFR2FGFRTK2psqB-Human530
FGFR2FGFRTK2q0bBphosphomethylphosphonic acid adenylate esterHuman499
FGFR2FGFRTK2py3Bphosphomethylphosphonic acid adenylate esterHuman484
FGFR2FGFRTK4j95DBphosphomethylphosphonic acid adenylate esterHuman492
FGFR2FGFRTK6agxDAethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5h-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1h-imidazol-1-yl]acetateHuman11543
FGFR2FGFRTK2pwlBphosphomethylphosphonic acid adenylate esterHuman534
FGFR2FGFRTK5uglAAphosphoaminophosphonic acid-adenylate esterHuman7442
FGFR2FGFRTK8u1fAn-[4-(4-amino-7-methyl-5-{4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7h-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-2-methylpropanamideHuman15202
FGFR2FGFRTK5uglBBphosphoaminophosphonic acid-adenylate esterHuman7449
FGFR2FGFRTK2pvyAphosphomethylphosphonic acid adenylate esterHuman489
FGFR2FGFRTK4j99BBphosphomethylphosphonic acid adenylate esterHuman495
FGFR2FGFRTK8sweAAn-{4-[4-amino-5-(4-methoxyphenyl)-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}prop-2-enamideHuman15200
FGFR2FGFRTK5ugxAAphosphomethylphosphonic acid adenylate esterHuman7443
FGFR2FGFRTK4j97BBphosphomethylphosphonic acid adenylate esterHuman493
FGFR2FGFRTK5ui0AB-Human7447
FGFR2FGFRTK6v6qDphosphomethylphosphonic acid adenylate esterHuman12967
FGFR2FGFRTK4j99AAphosphomethylphosphonic acid adenylate esterHuman474
FGFR2FGFRTK8w2xA1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]propan-1-oneHuman15406
FGFR2FGFRTK5ui0BBphosphomethylphosphonic acid adenylate esterHuman7440
FGFR2FGFRTK2pz5Aphosphomethylphosphonic acid adenylate esterHuman511
FGFR2FGFRTK4j97AAphosphomethylphosphonic acid adenylate esterHuman496
FGFR2FGFRTK2pz5Bphosphomethylphosphonic acid adenylate esterHuman513
FGFR2FGFRTK4j99ACphosphomethylphosphonic acid adenylate esterHuman469
FGFR2FGFRTK4j99CBphosphomethylphosphonic acid adenylate esterHuman506
FGFR2FGFRTK5eg3Aphosphomethylphosphonic acid adenylate esterHuman6368
FGFR2FGFRTK2pvfAphosphomethylphosphonic acid adenylate esterHuman525
FGFR2FGFRTK5uhnABphosphomethylphosphonic acid adenylate esterHuman7441
FGFR2FGFRTK9u3nA~{n}-[4-[4-azanyl-7-methyl-5-[2-(3-methylimidazo[4,5-b]pyridin-6-yl)ethynyl]pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]prop-2-enamideHuman15407
FGFR2FGFRTK4j99BAphosphomethylphosphonic acid adenylate esterHuman518
FGFR2FGFRTK6lvkAn-ethyl-2-[[4-[[4-(4-methylpiperazin-1-yl)-3-(2-morpholin-4-ylethoxy)phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulfonamideHuman12131
FGFR2FGFRTK2pzpBphosphomethylphosphonic acid adenylate esterHuman524
FGFR2FGFRTK4j98AB-Human475
FGFR2FGFRTK4j98BAphosphomethylphosphonic acid adenylate esterHuman516
FGFR2FGFRTK2pvyDphosphomethylphosphonic acid adenylate esterHuman482
FGFR2FGFRTK5uhnBBphosphomethylphosphonic acid adenylate esterHuman7444
FGFR2FGFRTK4j96BBphosphomethylphosphonic acid adenylate esterHuman486
FGFR2FGFRTK8w3bAA1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-oneHuman15408
FGFR2FGFRTK7ozyAA4-[3-(4-piperazin-4-ium-1-ylphenyl)-1h-indazol-6-yl]phenolHuman13999
FGFR2FGFRTK5uglABphosphoaminophosphonic acid-adenylate esterHuman7452
FGFR2FGFRTK6agxDBethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5h-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1h-imidazol-1-yl]acetateHuman11539
FGFR2FGFRTK2pzrAphosphomethylphosphonic acid adenylate esterHuman526
FGFR2FGFRTK8w3dAB1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-oneHuman15409
FGFR2FGFRTK4j99DAphosphomethylphosphonic acid adenylate esterHuman533
FGFR2FGFRTK1gjoA-Human478
FGFR2FGFRTK5ugxBAphosphomethylphosphonic acid adenylate esterHuman7454
FGFR2FGFRTK4j99CCphosphomethylphosphonic acid adenylate esterHuman471
FGFR2FGFRTK7kiaAA1-[4-(4-{4-(4-methylpiperazin-1-yl)-6-[(3-methyl-1h-pyrazol-5-yl)amino]pyrimidin-2-yl}phenyl)piperidin-1-yl]prop-2-en-1-oneHuman13283
FGFR2FGFRTK2pzpAphosphomethylphosphonic acid adenylate esterHuman497
FGFR2FGFRTK7kieBBn-{4-[(e)-2-{4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}ethenyl]phenyl}prop-2-enamideHuman13284
FGFR2FGFRTK2q0bAphosphomethylphosphonic acid adenylate esterHuman512
FGFR2FGFRTK5uhnAAphosphomethylphosphonic acid adenylate esterHuman7455
FGFR2FGFRTK4j97DAphosphomethylphosphonic acid adenylate esterHuman507
FGFR2FGFRTK8w3dAA1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-oneHuman15410
FGFR2FGFRTK4j97ACphosphomethylphosphonic acid adenylate esterHuman521
FGFR2FGFRTK3b2tA5'-o-[(s)-hydroxy{[(s)-hydroxy(methyl)phosphoryl]oxy}phosphoryl]adenosineHuman520
FGFR2FGFRTK8w38AA1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-oneHuman15411
FGFR2FGFRTK9vlmA~{n}-[3-[2-[[3-[2-(dimethylamino)ethylsulfamoylmethyl]phenyl]amino]pyrimidin-4-yl]-1-methyl-indol-6-yl]propanamideHuman15413
FGFR2FGFRTK7kieABn-{4-[(e)-2-{4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}ethenyl]phenyl}prop-2-enamideHuman13286
FGFR2FGFRTK2pvyBphosphomethylphosphonic acid adenylate esterHuman504
FGFR2FGFRTK7kieAAn-{4-[(e)-2-{4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}ethenyl]phenyl}prop-2-enamideHuman13287
FGFR2FGFRTK7kiaBB1-[4-(4-{4-(4-methylpiperazin-1-yl)-6-[(3-methyl-1h-pyrazol-5-yl)amino]pyrimidin-2-yl}phenyl)piperidin-1-yl]prop-2-en-1-oneHuman13288
FGFR2FGFRTK6agxAAethyl [4-({3-[2-(3,5-dimethoxyphenyl)ethyl]-5h-pyrrolo[2,3-b]pyrazin-5-yl}sulfonyl)-1h-imidazol-1-yl]acetateHuman11541
FGFR2FGFRTK4j96AA-Human473
FGFR2FGFRTK8h75A4-[9-(2-chlorophenyl)-6-methyl-2,4,5,8,12-pentazatricyclo[8.4.0.0^{3,7}]tetradeca-1(10),3,6,8,11,13-hexaen-13-yl]morpholineHuman14860
FGFR2FGFRTK4j96BAphosphomethylphosphonic acid adenylate esterHuman485
FGFR2FGFRTK3ri1B(6s)-6-phenyl-5,6-dihydrobenzo[h]quinazolin-2-amineHuman528
FGFR2FGFRTK3ri1A(6s)-6-phenyl-5,6-dihydrobenzo[h]quinazolin-2-amineHuman503
FGFR2FGFRTK8stgAn-{4-[(5p)-4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}-2-methylprop-2-enamideHuman14762
FGFR2FGFRTK4j98AA-Human500
FGFR2FGFRTK7kiaBA1-[4-(4-{4-(4-methylpiperazin-1-yl)-6-[(3-methyl-1h-pyrazol-5-yl)amino]pyrimidin-2-yl}phenyl)piperidin-1-yl]prop-2-en-1-oneHuman13281
FGFR2FGFRTK1oecA4-aryl-2-phenylamino pyrimidineHuman479
FGFR2FGFRTK4j95CBphosphomethylphosphonic acid adenylate esterHuman502
FGFR2FGFRTK2py3Aphosphomethylphosphonic acid adenylate esterHuman509
FGFR2FGFRTK3clyAphosphomethylphosphonic acid adenylate esterHuman522
FGFR2FGFRTK7ozyAB4-[3-(4-piperazin-4-ium-1-ylphenyl)-1h-indazol-6-yl]phenolHuman13998
FGFR2FGFRTK4j99CAphosphomethylphosphonic acid adenylate esterHuman505
FGFR2FGFRTK4j99DCphosphomethylphosphonic acid adenylate esterHuman480
FGFR2FGFRTK4j99BCphosphomethylphosphonic acid adenylate esterHuman491
FGFR2FGFRTK2psqA-Human515
FGFR2FGFRTK2pzrBphosphomethylphosphonic acid adenylate esterHuman508
FGFR2FGFRTK5ui0AA-Human7446
FGFR2FGFRTK4j97ABphosphomethylphosphonic acid adenylate esterHuman527
FGFR2FGFRTK8sweABn-{4-[4-amino-5-(4-methoxyphenyl)-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}prop-2-enamideHuman15201
FGFR2FGFRTK4j99ABphosphomethylphosphonic acid adenylate esterHuman494
FGFR2FGFRTK5ui0BAphosphomethylphosphonic acid adenylate esterHuman7453
FGFR2FGFRTK3b2tB5'-o-[(s)-hydroxy{[(s)-hydroxy(methyl)phosphoryl]oxy}phosphoryl]adenosineHuman517
FGFR2FGFRTK8w3bAB1-[(3s)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1h-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-oneHuman15412
FGFR2FGFRTK4j97CBphosphomethylphosphonic acid adenylate esterHuman487
FGFR2FGFRTK4j97DCphosphomethylphosphonic acid adenylate esterHuman514
FGFR2FGFRTK10ooA(4p)-n-[4-(4-aminopiperidin-1-yl)-2-methoxyphenyl]-5-chloro-4-(1h-indol-3-yl)pyrimidin-2-amineHuman15414
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