| Ern1 (IRE1) | IRE | Other | 4pl3 | A | | adenosine-5'-diphosphate | Mouse | 5769 | |
| ERN1 (IRE1) | IRE | Other | 6w3k | A | | 4-[5-[2,6-bis(fluoranyl)phenyl]-2~{h}-pyrazolo[3,4-b]pyridin-3-yl]-2-(4-oxidanylpiperidin-1-yl)-1~{h}-pyrimidin-6-one | Human | 13123 | |
| ERN1 (IRE1) | IRE | Other | 6xdb | A | | 4-amino-n-(6-chloro-2-fluoro-3-{[(2-fluorophenyl)sulfonyl]amino}phenyl)-6-(1,3-dimethyl-1h-pyrazol-4-yl)quinazoline-8-carboxamide | Human | 13531 | |
| ERN1 (IRE1) | IRE | Other | 6urc | B | | 2-chloro-n-(6-methyl-5-{[3-(2-{[(3s)-piperidin-3-yl]amino}pyrimidin-4-yl)pyridin-2-yl]oxy}naphthalen-1-yl)benzene-1-sulfonamide | Human | 11798 | |
| ERN1 (IRE1) | IRE | Other | 3p23 | A | | adenosine-5'-diphosphate | Human | 1795 | |
| ERN1 (IRE1) | IRE | Other | 4yzd | C | B | adenosine-5'-diphosphate | Human | 6226 | |
| ERN1 (IRE1) | IRE | Other | 3p23 | B | | adenosine-5'-diphosphate | Human | 1797 | |
| ERN1 (IRE1) | IRE | Other | 3p23 | C | | adenosine-5'-diphosphate | Human | 1798 | |
| ERN1 (IRE1) | IRE | Other | 4z7h | A | | 2-methoxy-4-[6-(propan-2-ylamino)imidazo[1,2-b]pyridazin-3-yl]benzamide | Human | 1794 | |
| ERN1 (IRE1) | IRE | Other | 4yzc | A | A | staurosporine | Human | 6235 | |
| ERN1 (IRE1) | IRE | Other | 6w3e | B | | methyl ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]carbamate | Human | 13126 | |
| ERN1 (IRE1) | IRE | Other | 3p23 | D | | adenosine-5'-diphosphate | Human | 1800 | |
| ERN1 (IRE1) | IRE | Other | 9n88 | A | | - | Human | 15450 | |
| ERN1 (IRE1) | IRE | Other | 9gow | A | | 3-[5-bromanyl-2-methyl-1-(phenylcarbonyl)indol-3-yl]propanoic acid | Human | 15451 | |
| ERN1 (IRE1) | IRE | Other | 6hx1 | A | B | 6-chloranyl-~{n}-(cyclopropylmethyl)-3-(2~{h}-indazol-5-yl)imidazo[1,2-b]pyridazin-8-amine | Human | 10929 | |
| ERN1 (IRE1) | IRE | Other | 6w3a | B | B | ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]but-2-ynamide | Human | 13119 | |
| ERN1 (IRE1) | IRE | Other | 6w3c | B | | - | Human | 13038 | |
| ERN1 (IRE1) | IRE | Other | 6w3a | B | A | ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]but-2-ynamide | Human | 13118 | |
| ERN1 (IRE1) | IRE | Other | 4z7g | A | | - | Human | 1799 | |
| ERN1 (IRE1) | IRE | Other | 6xdd | B | | 4-[(trans-4-aminocyclohexyl)amino]-n-(6-chloro-3-{[(2,5-difluorophenyl)sulfonyl]amino}-2-fluorophenyl)thieno[3,2-d]pyrimidine-7-carboxamide | Human | 13530 | |
| ERN1 (IRE1) | IRE | Other | 6w3c | D | | - | Human | 13037 | |
| ERN1 (IRE1) | IRE | Other | 6w39 | A | A | ethyl ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]carbamate | Human | 13120 | |
| ERN1 (IRE1) | IRE | Other | 6w3e | A | | methyl ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]carbamate | Human | 13121 | |
| ERN1 (IRE1) | IRE | Other | 4yzc | B | B | staurosporine | Human | 6231 | |
| ERN1 (IRE1) | IRE | Other | 6w39 | B | B | ethyl ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]carbamate | Human | 13124 | |
| ERN1 (IRE1) | IRE | Other | 6w3a | A | A | ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]but-2-ynamide | Human | 13125 | |
| ERN1 (IRE1) | IRE | Other | 4yz9 | B | B | (5r)-2-(3,4-dichlorobenzyl)-n-(4-methylbenzyl)-2,7-diazaspiro[4.5]decane-7-carboxamide | Human | 6229 | |
| ERN1 (IRE1) | IRE | Other | 6w3c | A | | - | Human | 13040 | |
| ERN1 (IRE1) | IRE | Other | 6xdd | A | | 4-[(trans-4-aminocyclohexyl)amino]-n-(6-chloro-3-{[(2,5-difluorophenyl)sulfonyl]amino}-2-fluorophenyl)thieno[3,2-d]pyrimidine-7-carboxamide | Human | 13529 | |
| ERN1 (IRE1) | IRE | Other | 4yz9 | A | A | (5r)-2-(3,4-dichlorobenzyl)-n-(4-methylbenzyl)-2,7-diazaspiro[4.5]decane-7-carboxamide | Human | 6233 | |
| ERN1 (IRE1) | IRE | Other | 6w3a | A | B | ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]but-2-ynamide | Human | 13116 | |
| ERN1 (IRE1) | IRE | Other | 4yzc | B | A | staurosporine | Human | 6227 | |
| ERN1 (IRE1) | IRE | Other | 4yz9 | B | A | (5r)-2-(3,4-dichlorobenzyl)-n-(4-methylbenzyl)-2,7-diazaspiro[4.5]decane-7-carboxamide | Human | 6225 | |
| ERN1 (IRE1) | IRE | Other | 6hx1 | A | A | 6-chloranyl-~{n}-(cyclopropylmethyl)-3-(2~{h}-indazol-5-yl)imidazo[1,2-b]pyridazin-8-amine | Human | 10927 | |
| ERN1 (IRE1) | IRE | Other | 4z7h | B | | 2-methoxy-4-[6-(propan-2-ylamino)imidazo[1,2-b]pyridazin-3-yl]benzamide | Human | 1801 | |
| ERN1 (IRE1) | IRE | Other | 4u6r | A | | n-{4-[(3-{2-[(trans-4-aminocyclohexyl)amino]pyrimidin-4-yl}pyridin-2-yl)oxy]-3-methylnaphthalen-1-yl}-2-chlorobenzenesulfonamide | Human | 1802 | |
| ERN1 (IRE1) | IRE | Other | 4yzd | A | A | adenosine-5'-diphosphate | Human | 6234 | |
| ERN1 (IRE1) | IRE | Other | 4yzd | C | A | adenosine-5'-diphosphate | Human | 6237 | |
| ERN1 (IRE1) | IRE | Other | 6w39 | B | A | ethyl ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]carbamate | Human | 13117 | |
| ERN1 (IRE1) | IRE | Other | 4yzd | A | B | adenosine-5'-diphosphate | Human | 6228 | |
| ERN1 (IRE1) | IRE | Other | 6xdf | B | B | - | Human | 13507 | |
| ERN1 (IRE1) | IRE | Other | 4yz9 | C | A | (5r)-2-(3,4-dichlorobenzyl)-n-(4-methylbenzyl)-2,7-diazaspiro[4.5]decane-7-carboxamide | Human | 6223 | |
| ERN1 (IRE1) | IRE | Other | 6w3b | A | | - | Human | 13039 | |
| ERN1 (IRE1) | IRE | Other | 4yzd | B | A | adenosine-5'-diphosphate | Human | 6236 | |
| ERN1 (IRE1) | IRE | Other | 6urc | A | | 2-chloro-n-(6-methyl-5-{[3-(2-{[(3s)-piperidin-3-yl]amino}pyrimidin-4-yl)pyridin-2-yl]oxy}naphthalen-1-yl)benzene-1-sulfonamide | Human | 11799 | |
| ERN1 (IRE1) | IRE | Other | 4z7g | B | | - | Human | 1796 | |
| ERN1 (IRE1) | IRE | Other | 6w39 | A | B | ethyl ~{n}-[6-methyl-5-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]carbamate | Human | 13122 | |
| ERN1 (IRE1) | IRE | Other | 6hv0 | A | | 6-chloranyl-3-(2~{h}-indazol-5-yl)-~{n}-propan-2-yl-imidazo[1,2-b]pyridazin-8-amine | Human | 10928 | |
| ERN1 (IRE1) | IRE | Other | 6xdf | B | A | - | Human | 13508 | |
| ERN1 (IRE1) | IRE | Other | 4yzd | B | B | adenosine-5'-diphosphate | Human | 6230 | |
| ERN1 (IRE1) | IRE | Other | 4yz9 | C | B | (5r)-2-(3,4-dichlorobenzyl)-n-(4-methylbenzyl)-2,7-diazaspiro[4.5]decane-7-carboxamide | Human | 6222 | |
| ERN1 (IRE1) | IRE | Other | 7bmk | A | A | 2,2,2-tris(fluoranyl)-~{n}-[4-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxynaphthalen-1-yl]ethanesulfonamide | Human | 13911 | |
| ERN1 (IRE1) | IRE | Other | 6w3c | C | | - | Human | 13036 | |
| ERN1 (IRE1) | IRE | Other | 4yzc | A | B | staurosporine | Human | 6232 | |
| ERN1 (IRE1) | IRE | Other | 4yz9 | A | B | (5r)-2-(3,4-dichlorobenzyl)-n-(4-methylbenzyl)-2,7-diazaspiro[4.5]decane-7-carboxamide | Human | 6224 | |
| ERN1 (IRE1) | IRE | Other | 5hgi | A | | - | Human | 6669 | |
| ERN1 (IRE1) | IRE | Other | 7bmk | A | B | 2,2,2-tris(fluoranyl)-~{n}-[4-[3-[2-[[(3~{s})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxynaphthalen-1-yl]ethanesulfonamide | Human | 13912 | |
| Ern1 (IRE1) | IRE | Other | 4pl3 | B | | adenosine-5'-diphosphate | Mouse | 5768 | |
| Ern1 (IRE1) | IRE | Other | 4pl4 | C | | adenosine-5'-diphosphate | Mouse | 5761 | |
| Ern1 (IRE1) | IRE | Other | 4pl5 | B | | adenosine-5'-diphosphate | Mouse | 5764 | |
| Ern1 (IRE1) | IRE | Other | 4pl5 | C | | adenosine-5'-diphosphate | Mouse | 5766 | |
| Ern1 (IRE1) | IRE | Other | 4pl5 | D | | adenosine-5'-diphosphate | Mouse | 5763 | |
| Ern1 (IRE1) | IRE | Other | 4pl4 | D | | adenosine-5'-diphosphate | Mouse | 5765 | |
| Ern1 (IRE1) | IRE | Other | 4pl4 | A | | adenosine-5'-diphosphate | Mouse | 5770 | |
| Ern1 (IRE1) | IRE | Other | 4pl4 | B | | adenosine-5'-diphosphate | Mouse | 5767 | |
| Ern1 (IRE1) | IRE | Other | 4pl5 | A | | adenosine-5'-diphosphate | Mouse | 5762 | |
