| JAK3 | JakA | TK | 4i6q | A | | n-[(1s)-1-cyclopropylethyl]-2-phenoxy-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 432 | |
| JAK3 | JakA | TK | 7uyv | A | B | 6-{[(2m)-2-(2-chloro-6-fluorophenyl)-5-oxo-5h-pyrrolo[3,4-b]pyridin-4-yl]amino}-n-ethylpyridine-3-carboxamide | Human | 14332 | |
| JAK3 | JakA | TK | 6hzv | D | A | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 11749 | |
| JAK3 | JakA | TK | 4rio | A | | 4-{[(1r,2s)-2-fluoro-2-methylcyclopentyl]amino}pyrrolo[1,2-b]pyridazine-3-carboxamide | Human | 440 | |
| JAK3 | JakA | TK | 4qps | A | B | n-{1-[6-(phenylamino)pyrazin-2-yl]-1h-benzimidazol-6-yl}prop-2-enamide | Human | 458 | |
| JAK3 | JakA | TK | 3zep | A | B | 2-[[(3r)-3-acetamido-2,3-dihydro-1h-inden-5-yl]oxy]-n-[(1s)-1-cyclopropylethyl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 456 | |
| JAK3 | JakA | TK | 7apf | B | B | 3-[3-(propanoylamino)phenyl]-1~{h}-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | 13132 | |
| JAK3 | JakA | TK | 5ttu | A | B | 1-[(3ar,7ar)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)octahydro-6h-pyrrolo[2,3-c]pyridin-6-yl]propan-1-one | Human | 7438 | |
| JAK3 | JakA | TK | 4z16 | C | | n-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamide | Human | 6397 | |
| JAK3 | JakA | TK | 7uyv | A | A | 6-{[(2m)-2-(2-chloro-6-fluorophenyl)-5-oxo-5h-pyrrolo[3,4-b]pyridin-4-yl]amino}-n-ethylpyridine-3-carboxamide | Human | 14331 | |
| JAK3 | JakA | TK | 6aak | D | | 4-[[(1s,3r)-5-oxidanyl-2-adamantyl]amino]-1h-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | 10365 | |
| JAK3 | JakA | TK | 6hzv | A | A | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 11756 | |
| JAK3 | JakA | TK | 3zep | D | A | 2-[[(3r)-3-acetamido-2,3-dihydro-1h-inden-5-yl]oxy]-n-[(1s)-1-cyclopropylethyl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 454 | |
| JAK3 | JakA | TK | 7apg | B | A | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | 13131 | |
| JAK3 | JakA | TK | 4hvh | A | | 2-cyclopropyl-n-[(2r)-3-hydroxy-3-methylbutan-2-yl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 441 | |
| JAK3 | JakA | TK | 6gla | B | A | (~{e})-3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)furan-2-yl]prop-2-enenitrile | Human | 10017 | |
| JAK3 | JakA | TK | 5w86 | B | A | 4-(benzylamino)-6-({4-[(1-methylpiperidin-4-yl)carbamoyl]phenyl}amino)pyridine-3-carboxamide | Human | 8551 | |
| JAK3 | JakA | TK | 5ttv | A | A | n-[3-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]propanamide | Human | 7437 | |
| JAK3 | JakA | TK | 3zep | B | B | 2-[[(3r)-3-acetamido-2,3-dihydro-1h-inden-5-yl]oxy]-n-[(1s)-1-cyclopropylethyl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 437 | |
| JAK3 | JakA | TK | 7c3n | A | B | 3-[(3s,4r)-3-methyl-7-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1,7-diazaspiro[3.4]octan-1-yl]-3-oxidanylidene-propanenitrile | Human | 12391 | |
| JAK3 | JakA | TK | 5vo6 | A | | 4-{[(1r,3s)-3-amino-2,2,3-trimethylcyclopentyl]amino}-6-phenylpyrrolo[1,2-b]pyridazine-3-carboxamide | Human | 7960 | |
| JAK3 | JakA | TK | 7apg | D | A | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | 13138 | |
| JAK3 | JakA | TK | 3zep | C | B | 2-[[(3r)-3-acetamido-2,3-dihydro-1h-inden-5-yl]oxy]-n-[(1s)-1-cyclopropylethyl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 462 | |
| JAK3 | JakA | TK | 6aak | B | | 4-[[(1s,3r)-5-oxidanyl-2-adamantyl]amino]-1h-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | 10367 | |
| JAK3 | JakA | TK | 3zep | C | A | 2-[[(3r)-3-acetamido-2,3-dihydro-1h-inden-5-yl]oxy]-n-[(1s)-1-cyclopropylethyl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 439 | |
| JAK3 | JakA | TK | 6hzv | B | B | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 11754 | |
| JAK3 | JakA | TK | 6aak | C | | 4-[[(1s,3r)-5-oxidanyl-2-adamantyl]amino]-1h-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | 10368 | |
| JAK3 | JakA | TK | 3lxk | A | | 3-{(3r,4r)-4-methyl-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile | Human | 436 | |
| JAK3 | JakA | TK | 6ny4 | A | | 4-{[(2r,3r)-1,3-dihydroxybutan-2-yl]amino}-6-phenylpyrrolo[1,2-b]pyridazine-3-carboxamide | Human | 11052 | |
| JAK3 | JakA | TK | 7apg | A | B | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | 13135 | |
| JAK3 | JakA | TK | 7q6h | A | A | 1-[4-[[2-[(1-methylpyrazol-4-yl)amino]quinazolin-8-yl]amino]piperidin-1-yl]ethanone | Human | 14080 | |
| JAK3 | JakA | TK | 7apg | D | B | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | 13133 | |
| JAK3 | JakA | TK | 6hzv | B | A | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 11753 | |
| JAK3 | JakA | TK | 6gl9 | B | A | (~{e})-3-[3-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)phenyl]prop-2-enenitrile | Human | 10019 | |
| JAK3 | JakA | TK | 6dud | A | B | n-[(1s)-6-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1h-inden-1-yl]imidoformamide | Human | 10720 | |
| JAK3 | JakA | TK | 4v0g | B | A | n-[3-(2-{3-amino-6-[1-(1-methylpiperidin-4-yl)-1h-pyrazol-4-yl]pyrazin-2-yl}-1h-benzimidazol-1-yl)phenyl]propanamide | Human | 6348 | |
| JAK3 | JakA | TK | 6gla | A | A | (~{e})-3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)furan-2-yl]prop-2-enenitrile | Human | 10018 | |
| JAK3 | JakA | TK | 3zc6 | A | B | n-[(2r)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 461 | |
| JAK3 | JakA | TK | 6db4 | A | A | n-[(1s)-6-(5-phenyl-7h-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1h-inden-1-yl]imidoformamide | Human | 10724 | |
| JAK3 | JakA | TK | 4hvi | A | | 2-cyclopropyl-n-[(2r)-1-oxo-1-(piperidin-1-yl)propan-2-yl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 438 | |
| JAK3 | JakA | TK | 7apg | C | A | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | 13140 | |
| JAK3 | JakA | TK | 6gla | B | B | (~{e})-3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)furan-2-yl]prop-2-enenitrile | Human | 10022 | |
| JAK3 | JakA | TK | 3zep | B | A | 2-[[(3r)-3-acetamido-2,3-dihydro-1h-inden-5-yl]oxy]-n-[(1s)-1-cyclopropylethyl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 430 | |
| JAK3 | JakA | TK | 4z16 | D | | n-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamide | Human | 6394 | |
| JAK3 | JakA | TK | 6db3 | A | A | [(1s)-1-methyl-6-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1h-inden-1-yl]cyanamide | Human | 10718 | |
| JAK3 | JakA | TK | 6aak | A | | 4-[[(1s,3r)-5-oxidanyl-2-adamantyl]amino]-1h-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | 10366 | |
| JAK3 | JakA | TK | 5lwn | A | A | (~{z})-2-cyano-~{n},~{n}-dimethyl-3-[5-[3-[(1~{s},2~{r})-2-methylcyclohexyl]-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1,4,6,8,11-pentaen-4-yl]furan-2-yl]prop-2-enamide | Human | 7117 | |
| JAK3 | JakA | TK | 7apg | B | B | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | 13136 | |
| JAK3 | JakA | TK | 3zc6 | B | B | n-[(2r)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 447 | |
| JAK3 | JakA | TK | 4v0g | A | B | n-[3-(2-{3-amino-6-[1-(1-methylpiperidin-4-yl)-1h-pyrazol-4-yl]pyrazin-2-yl}-1h-benzimidazol-1-yl)phenyl]propanamide | Human | 6346 | |
| JAK3 | JakA | TK | 3lxl | A | B | 2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one | Human | 443 | |
| JAK3 | JakA | TK | 5toz | A | | 1-{(2s,5r)-2-methyl-5-[(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}propan-1-one | Human | 7163 | |
| JAK3 | JakA | TK | 6da4 | A | | (z)-1-{2,2-difluoro-6-[5-(2-methoxyethyl)-7h-pyrrolo[2,3-d]pyrimidin-4-yl]-2,3-dihydro-4h-1,4-benzoxazin-4-yl}methanimine | Human | 10723 | |
| JAK3 | JakA | TK | 5lwn | A | B | (2~{s})-2-cyano-~{n},~{n}-dimethyl-3-[5-[3-[(1~{s},2~{r})-2-methylcyclohexyl]-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1,4,6,8,11-pentaen-4-yl]furan-2-yl]propanamide | Human | 7116 | |
| JAK3 | JakA | TK | 3zc6 | C | B | n-[(2r)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 445 | |
| JAK3 | JakA | TK | 5lwm | A | B | 2-cyano-3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1,4,6,8,11-pentaen-4-yl)furan-2-yl]-~{n},~{n}-dimethyl-prop-2-enamide | Human | 7118 | |
| JAK3 | JakA | TK | 6gl9 | A | A | (~{e})-3-[3-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)phenyl]prop-2-enenitrile | Human | 10014 | |
| JAK3 | JakA | TK | 7apf | A | B | 3-[3-(propanoylamino)phenyl]-1~{h}-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | 13130 | |
| JAK3 | JakA | TK | 1yvj | A | A | 1,2,3,4-tetrahydrogen-staurosporine | Human | 460 | |
| JAK3 | JakA | TK | 6glb | A | B | 3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)furan-2-yl]propanenitrile | Human | 10023 | |
| JAK3 | JakA | TK | 4hvg | A | | 2-cyclopropyl-n-[(2s)-3-hydroxy-3-methylbutan-2-yl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 450 | |
| JAK3 | JakA | TK | 3zc6 | D | B | n-[(2r)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 459 | |
| JAK3 | JakA | TK | 7q6h | A | C | 1-[4-[[2-[(1-methylpyrazol-4-yl)amino]quinazolin-8-yl]amino]piperidin-1-yl]ethanone | Human | 14081 | |
| JAK3 | JakA | TK | 5ttu | A | A | 1-[(3ar,7ar)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)octahydro-6h-pyrrolo[2,3-c]pyridin-6-yl]propan-1-one | Human | 7435 | |
| JAK3 | JakA | TK | 3zc6 | A | A | n-[(2r)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 442 | |
| JAK3 | JakA | TK | 4v0g | A | A | n-[3-(2-{3-amino-6-[1-(1-methylpiperidin-4-yl)-1h-pyrazol-4-yl]pyrazin-2-yl}-1h-benzimidazol-1-yl)phenyl]propanamide | Human | 6347 | |
| JAK3 | JakA | TK | 5wfj | A | | 4-({[3-(propanoylamino)phenyl]methyl}amino)pyrrolo[1,2-b]pyridazine-3-carboxamide | Human | 8535 | |
| JAK3 | JakA | TK | 6glb | B | A | 3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)furan-2-yl]propanenitrile | Human | 10021 | |
| JAK3 | JakA | TK | 4z16 | A | | n-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamide | Human | 6395 | |
| JAK3 | JakA | TK | 3zc6 | C | A | n-[(2r)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 433 | |
| JAK3 | JakA | TK | 5tts | A | | 1-{(3r)-3-[(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}propan-1-one | Human | 7439 | |
| JAK3 | JakA | TK | 3lxl | A | A | 2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one | Human | 434 | |
| JAK3 | JakA | TK | 7c3n | A | A | 3-[(3s,4r)-3-methyl-7-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1,7-diazaspiro[3.4]octan-1-yl]-3-oxidanylidene-propanenitrile | Human | 12389 | |
| JAK3 | JakA | TK | 6hzv | C | B | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 11755 | |
| JAK3 | JakA | TK | 3pjc | A | | 3-(1h-indol-3-yl)-4-[2-(4-oxopiperidin-1-yl)-5-(trifluoromethyl)pyrimidin-4-yl]-1h-pyrrole-2,5-dione | Human | 444 | |
| JAK3 | JakA | TK | 3zc6 | D | A | n-[(2r)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 446 | |
| JAK3 | JakA | TK | 6db4 | A | B | n-[(1s)-6-(5-phenyl-7h-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1h-inden-1-yl]imidoformamide | Human | 10721 | |
| JAK3 | JakA | TK | 6gl9 | A | B | (~{e})-3-[3-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)phenyl]prop-2-enenitrile | Human | 10016 | |
| JAK3 | JakA | TK | 9r5z | A | | 3-(3-cyclohexyl-3,8,10-triazatricyclo[7.3.0.0^{2,6}]dodeca-1,4,6,8,11-pentaen-5-yl)benzenesulfonyl fluoride | Human | 15522 | |
| JAK3 | JakA | TK | 5w86 | C | A | 4-(benzylamino)-6-({4-[(1-methylpiperidin-4-yl)carbamoyl]phenyl}amino)pyridine-3-carboxamide | Human | 8550 | |
| JAK3 | JakA | TK | 6dud | A | A | n-[(1s)-6-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1h-inden-1-yl]imidoformamide | Human | 10722 | |
| JAK3 | JakA | TK | 6hzv | C | A | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 11752 | |
| JAK3 | JakA | TK | 6gla | A | B | (~{e})-3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)furan-2-yl]prop-2-enenitrile | Human | 10012 | |
| JAK3 | JakA | TK | 7apg | A | A | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | 13134 | |
| JAK3 | JakA | TK | 6glb | A | A | 3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)furan-2-yl]propanenitrile | Human | 10020 | |
| JAK3 | JakA | TK | 4qps | A | A | n-{1-[6-(phenylamino)pyrazin-2-yl]-1h-benzimidazol-6-yl}prop-2-enamide | Human | 453 | |
| JAK3 | JakA | TK | 6glb | B | B | 3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)furan-2-yl]propanenitrile | Human | 10015 | |
| JAK3 | JakA | TK | 5lwm | A | A | 2-cyano-3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1,4,6,8,11-pentaen-4-yl)furan-2-yl]-~{n},~{n}-dimethyl-prop-2-enamide | Human | 7115 | |
| JAK3 | JakA | TK | 7q6h | A | B | 1-[4-[[2-[(1-methylpyrazol-4-yl)amino]quinazolin-8-yl]amino]piperidin-1-yl]ethanone | Human | 14082 | |
| JAK3 | JakA | TK | 4qps | C | A | n-{1-[6-(phenylamino)pyrazin-2-yl]-1h-benzimidazol-6-yl}prop-2-enamide | Human | 435 | |
| JAK3 | JakA | TK | 1yvj | A | B | 1,2,3,4-tetrahydrogen-staurosporine | Human | 451 | |
| JAK3 | JakA | TK | 4qt1 | A | | 1-{(3s)-1-[(2-methylpropyl)sulfonyl]piperidin-3-yl}-3-(5h-pyrrolo[2,3-b]pyrazin-2-yl)urea | Human | 452 | |
| JAK3 | JakA | TK | 6gl9 | B | B | (~{e})-3-[3-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),4,7,11-pentaen-4-yl)phenyl]prop-2-enenitrile | Human | 10013 | |
| JAK3 | JakA | TK | 7apf | B | A | 3-[3-(propanoylamino)phenyl]-1~{h}-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | 13137 | |
| JAK3 | JakA | TK | 4hvd | A | | 2-cyclopropyl-n-[(2s)-3,3-dimethylbutan-2-yl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 431 | |
| JAK3 | JakA | TK | 4qps | C | B | n-{1-[6-(phenylamino)pyrazin-2-yl]-1h-benzimidazol-6-yl}prop-2-enamide | Human | 455 | |
| JAK3 | JakA | TK | 3zep | A | A | 2-[[(3r)-3-acetamido-2,3-dihydro-1h-inden-5-yl]oxy]-n-[(1s)-1-cyclopropylethyl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 448 | |
| JAK3 | JakA | TK | 4v0g | B | B | n-[3-(2-{3-amino-6-[1-(1-methylpiperidin-4-yl)-1h-pyrazol-4-yl]pyrazin-2-yl}-1h-benzimidazol-1-yl)phenyl]propanamide | Human | 6345 | |
| JAK3 | JakA | TK | 4z16 | B | | n-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamide | Human | 6396 | |
| JAK3 | JakA | TK | 6db3 | A | B | [(1s)-1-methyl-6-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1h-inden-1-yl]cyanamide | Human | 10719 | |
| JAK3 | JakA | TK | 7c3n | A | C | 3-[(3s,4r)-3-methyl-7-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1,7-diazaspiro[3.4]octan-1-yl]-3-oxidanylidene-propanenitrile | Human | 12390 | |
| JAK3 | JakA | TK | 5ttv | A | B | n-[3-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]propanamide | Human | 7436 | |
| JAK3 | JakA | TK | 8rpn | A | | 3-[4-[[(3~{r})-1-(2-cyanoethanoyl)piperidin-3-yl]amino]pyrimidin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 15523 | |
| JAK3 | JakA | TK | 7apg | C | B | ~{n}-[3-(1~{h}-pyrrolo[2,3-b]pyridin-3-yl)phenyl]propanamide | Human | 13139 | |
| JAK3 | JakA | TK | 5w86 | D | A | 4-(benzylamino)-6-({4-[(1-methylpiperidin-4-yl)carbamoyl]phenyl}amino)pyridine-3-carboxamide | Human | 8548 | |
| JAK3 | JakA | TK | 5w86 | A | A | 4-(benzylamino)-6-({4-[(1-methylpiperidin-4-yl)carbamoyl]phenyl}amino)pyridine-3-carboxamide | Human | 8549 | |
| JAK3 | JakA | TK | 7apf | A | A | 3-[3-(propanoylamino)phenyl]-1~{h}-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | 13141 | |
| JAK3 | JakA | TK | 3zep | D | B | 2-[[(3r)-3-acetamido-2,3-dihydro-1h-inden-5-yl]oxy]-n-[(1s)-1-cyclopropylethyl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 457 | |
| JAK3 | JakA | TK | 3zc6 | B | A | n-[(2r)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | 449 | |
| JAK3 | JakA | TK | 6hzv | A | B | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 11751 | |
| JAK3 | JakA | TK | 6hzv | D | B | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 11750 | |
