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Search results (74 entries covering 40 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetails File
MAPK8 (JNK1)MAPKCMGC3o2mB-Human4649
MAPK8 (JNK1)MAPKCMGC2xrwAAphosphoaminophosphonic acid-adenylate esterHuman4675
MAPK8 (JNK1)MAPKCMGC3vulA-Human4633
MAPK8 (JNK1)MAPKCMGC4ux9DBphosphoaminophosphonic acid-adenylate esterHuman4666
MAPK8 (JNK1)MAPKCMGC4yr8CB-Human6447
MAPK8 (JNK1)MAPKCMGC4ux9CBphosphoaminophosphonic acid-adenylate esterHuman4647
MAPK8 (JNK1)MAPKCMGC4l7fABn-[1-(4-fluorophenyl)cyclopropyl]-4-[(trans-4-hydroxycyclohexyl)amino]imidazo[1,2-a]quinoxaline-8-carboxamideHuman4637
MAPK8 (JNK1)MAPKCMGC2g01A6-chloro-9-hydroxy-1,3-dimethyl-1,9-dihydro-4h-pyrazolo[3,4-b]quinolin-4-oneHuman4662
MAPK8 (JNK1)MAPKCMGC3o17A-Human4670
MAPK8 (JNK1)MAPKCMGC2no3B2-({2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}amino)benzamideHuman4657
MAPK8 (JNK1)MAPKCMGC3v3vA3,5,6,7-tetrahydroxy-2-(3,4-dihydroxyphenyl)-4h-chromen-4-oneHuman4653
MAPK8 (JNK1)MAPKCMGC4yr8FB-Human6453
MAPK8 (JNK1)MAPKCMGC3vugA-Human4665
MAPK8 (JNK1)MAPKCMGC4awiABn-(1,1-dioxidotetrahydro-2h-thiopyran-4-yl)-4-[2-(1-methylethyl)-1h-pyrrolo[2,3-b]pyridin-4-yl]benzenesulfonamideHuman4634
MAPK8 (JNK1)MAPKCMGC6zr5Aphosphoaminophosphonic acid-adenylate esterHuman12984
MAPK8 (JNK1)MAPKCMGC4yr8CA-Human6449
MAPK8 (JNK1)MAPKCMGC1ukhA-Human4628
MAPK8 (JNK1)MAPKCMGC2h96A5-cyano-n-(2,5-dimethoxybenzyl)-6-ethoxypyridine-2-carboxamideHuman4655
MAPK8 (JNK1)MAPKCMGC4qtdAA(3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamideHuman4651
MAPK8 (JNK1)MAPKCMGC4g1wAmethyl 7-fluoro-3-{4-[(2-hydroxyethyl)sulfonyl]benzyl}-4-oxo-1-phenyl-1,4-dihydroquinoline-2-carboxylateHuman4631
MAPK8 (JNK1)MAPKCMGC2xs0Aphosphoaminophosphonic acid-adenylate esterHuman4629
MAPK8 (JNK1)MAPKCMGC2gmxBn-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-bromo-2,5-dimethoxyphenyl)acetamideHuman4638
MAPK8 (JNK1)MAPKCMGC1ukiA2,6-dihydroanthra/1,9-cd/pyrazol-6-oneHuman4630
MAPK8 (JNK1)MAPKCMGC4yr8EA-Human6451
MAPK8 (JNK1)MAPKCMGC6zr5Bphosphoaminophosphonic acid-adenylate esterHuman12985
MAPK8 (JNK1)MAPKCMGC4hysAtrans-4-{[4-(1h-indazol-1-yl)pyrimidin-2-yl]amino}cyclohexanolHuman4672
MAPK8 (JNK1)MAPKCMGC3vuiA-Human4652
MAPK8 (JNK1)MAPKCMGC4ux9ABphosphoaminophosphonic acid-adenylate esterHuman4646
MAPK8 (JNK1)MAPKCMGC2xrwACphosphoaminophosphonic acid-adenylate esterHuman4660
MAPK8 (JNK1)MAPKCMGC3vudA-Human4664
MAPK8 (JNK1)MAPKCMGC2no3A2-({2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}amino)benzamideHuman4640
MAPK8 (JNK1)MAPKCMGC4awiAAn-(1,1-dioxidotetrahydro-2h-thiopyran-4-yl)-4-[2-(1-methylethyl)-1h-pyrrolo[2,3-b]pyridin-4-yl]benzenesulfonamideHuman4661
MAPK8 (JNK1)MAPKCMGC6f5eB-Human9078
MAPK8 (JNK1)MAPKCMGC5lw1HadenosineHuman9080
MAPK8 (JNK1)MAPKCMGC4ux9BBphosphoaminophosphonic acid-adenylate esterHuman4656
MAPK8 (JNK1)MAPKCMGC11zlAA(4m)-n-[4-hydroxy-3-(pyrrolidine-1-carbonyl)phenyl]-4-(1h-pyrrolo[2,3-b]pyridin-5-yl)-1-benzothiophene-2-carboxamideHuman15534
MAPK8 (JNK1)MAPKCMGC4e73ABmethyl 3-(4-{[(1r,2s,3s,5s,7s)-5-aminotricyclo[3.3.1.1~3,7~]dec-2-yl]carbamoyl}benzyl)-4-oxo-1-phenyl-1,4-dihydro-1,8-naphthyridine-2-carboxylateHuman4669
MAPK8 (JNK1)MAPKCMGC5lw1EadenosineHuman9079
MAPK8 (JNK1)MAPKCMGC4yr8EB-Human6454
MAPK8 (JNK1)MAPKCMGC3o17B-Human4667
MAPK8 (JNK1)MAPKCMGC4yr8AB-Human6448
MAPK8 (JNK1)MAPKCMGC3o2mA-Human4676
MAPK8 (JNK1)MAPKCMGC4ux9DAphosphoaminophosphonic acid-adenylate esterHuman4627
MAPK8 (JNK1)MAPKCMGC4l7fACn-[1-(4-fluorophenyl)cyclopropyl]-4-[(trans-4-hydroxycyclohexyl)amino]imidazo[1,2-a]quinoxaline-8-carboxamideHuman4648
MAPK8 (JNK1)MAPKCMGC3vukA-Human4659
MAPK8 (JNK1)MAPKCMGC2h96B5-cyano-n-(2,5-dimethoxybenzyl)-6-ethoxypyridine-2-carboxamideHuman4668
MAPK8 (JNK1)MAPKCMGC4ux9CAphosphoaminophosphonic acid-adenylate esterHuman4644
MAPK8 (JNK1)MAPKCMGC8x5mAB3-[4-(dimethylamino)butanoylamino]-~{n}-[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamideHuman15100
MAPK8 (JNK1)MAPKCMGC3pzeA3-(carbamoylamino)-5-phenylthiophene-2-carboxamideHuman4642
MAPK8 (JNK1)MAPKCMGC8pt9Amethyl (1s,3s)-1-methyl-3-[[3-[[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]carbamoyl]-4-oxidanylidene-cyclohexane-1-carboxylateHuman15293
MAPK8 (JNK1)MAPKCMGC8ptaAmethyl (1r,3s)-1-methyl-3-[[3-[[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]carbamoyl]-4-oxidanylidene-cyclohexane-1-carboxylateHuman15294
MAPK8 (JNK1)MAPKCMGC8pt8Amethyl (1r,3r)-1-methyl-3-[[3-[[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]methylcarbamoyl]-4-oxidanylidene-cyclohexane-1-carboxylateHuman15295
MAPK8 (JNK1)MAPKCMGC5lw1BadenosineHuman9081
MAPK8 (JNK1)MAPKCMGC4yr8AA-Human6452
MAPK8 (JNK1)MAPKCMGC4ux9AAphosphoaminophosphonic acid-adenylate esterHuman4643
MAPK8 (JNK1)MAPKCMGC2gmxAn-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(4-bromo-2,5-dimethoxyphenyl)acetamideHuman4674
MAPK8 (JNK1)MAPKCMGC9ft9Aphosphoaminophosphonic acid-adenylate esterHuman15532
MAPK8 (JNK1)MAPKCMGC3vuhA-Human4663
MAPK8 (JNK1)MAPKCMGC2g01B6-chloro-9-hydroxy-1,3-dimethyl-1,9-dihydro-4h-pyrazolo[3,4-b]quinolin-4-oneHuman4641
MAPK8 (JNK1)MAPKCMGC12cvAA(4m)-n-[3-(dimethylcarbamoyl)-4-hydroxyphenyl]-4-(1h-pyrrolo[2,3-b]pyridin-5-yl)-3h-1lambda~4~-benzothiophene-2-carboxamideHuman15533
MAPK8 (JNK1)MAPKCMGC4qtdAB(3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamideHuman4673
MAPK8 (JNK1)MAPKCMGC4hyuAtrans-4-[(4-{4-[3-(methylsulfonyl)propoxy]-1h-indazol-1-yl}pyrimidin-2-yl)amino]cyclohexanolHuman4632
MAPK8 (JNK1)MAPKCMGC4l7fAAn-[1-(4-fluorophenyl)cyclopropyl]-4-[(trans-4-hydroxycyclohexyl)amino]imidazo[1,2-a]quinoxaline-8-carboxamideHuman4639
MAPK8 (JNK1)MAPKCMGC4e73AAmethyl 3-(4-{[(1r,2s,3s,5s,7s)-5-aminotricyclo[3.3.1.1~3,7~]dec-2-yl]carbamoyl}benzyl)-4-oxo-1-phenyl-1,4-dihydro-1,8-naphthyridine-2-carboxylateHuman4645
MAPK8 (JNK1)MAPKCMGC4ux9BAphosphoaminophosphonic acid-adenylate esterHuman4635
MAPK8 (JNK1)MAPKCMGC4izyAtrans-4-[(4-{4-[4-(methylsulfonyl)piperidin-1-yl]-1h-indol-1-yl}pyrimidin-2-yl)amino]cyclohexanolHuman4654
MAPK8 (JNK1)MAPKCMGC11zlAB(4m)-n-[4-hydroxy-3-(pyrrolidine-1-carbonyl)phenyl]-4-(1h-pyrrolo[2,3-b]pyridin-5-yl)-1-benzothiophene-2-carboxamideHuman15535
MAPK8 (JNK1)MAPKCMGC4yr8FA-Human6450
MAPK8 (JNK1)MAPKCMGC2xrwABphosphoaminophosphonic acid-adenylate esterHuman4650
MAPK8 (JNK1)MAPKCMGC12cvAB(4m)-n-[3-(dimethylcarbamoyl)-4-hydroxyphenyl]-4-(1h-pyrrolo[2,3-b]pyridin-5-yl)-3h-1lambda~4~-benzothiophene-2-carboxamideHuman15536
MAPK8 (JNK1)MAPKCMGC3vumA-Human4671
MAPK8 (JNK1)MAPKCMGC3eljAA2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7h-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamideHuman4658
MAPK8 (JNK1)MAPKCMGC3eljAB2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7h-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamideHuman4636
MAPK8 (JNK1)MAPKCMGC8x5mAA3-[4-(dimethylamino)butanoylamino]-~{n}-[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamideHuman15099
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