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Search results (77 entries covering 24 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetails File
MAP3K5STE11STE7mu7AB3-methoxy-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}-1-(pyrazin-2-yl)-1h-pyrazole-4-carboxamideHuman14220
MAP3K5STE11STE2clqABstaurosporineHuman4736
MAP3K5STE11STE4bidBA5-[(1r)-2-amino-1-phenylethoxy]-2-(furan-3-yl)-3-{1h-pyrrolo[2,3-b]pyridin-3-yl}pyridineHuman4742
MAP3K5STE11STE4bidAA5-[(1r)-2-amino-1-phenylethoxy]-2-(furan-3-yl)-3-{1h-pyrrolo[2,3-b]pyridin-3-yl}pyridineHuman4756
MAP3K5STE11STE8qgyA-Human15268
MAP3K5STE11STE5vioC-Human9511
MAP3K5STE11STE4bhnBA4-tert-butyl-n-[6-(1h-pyrazol-4-yl)imidazo[1,2-a]pyridin-2-yl]benzamideHuman4734
MAP3K5STE11STE2clqBAstaurosporineHuman4755
MAP3K5STE11STE5up3B2-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}-2,3-dihydro-1h-isoindol-1-oneHuman8110
MAP3K5STE11STE4bhnAA4-tert-butyl-n-[6-(1h-pyrazol-4-yl)imidazo[1,2-a]pyridin-2-yl]benzamideHuman4754
MAP3K5STE11STE6oytA5-(4-cyclopropyl-1h-imidazol-1-yl)-2-fluoro-4-methyl-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}benzamideHuman11837
MAP3K5STE11STE6xihBB(2r)-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}oxane-2-carboxamideHuman12701
MAP3K5STE11STE5v19An-(1-ethyl-1h-pyrazol-4-yl)furan-3-carboxamideHuman8025
MAP3K5STE11STE6vreAB3-methoxy-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}-1-(pyrazin-2-yl)-1h-pyrazole-4-carboxamideHuman12233
MAP3K5STE11STE6e2oB4-(4-cyclopropyl-1h-imidazol-1-yl)-n-[3-(4-cyclopropyl-4h-1,2,4-triazol-3-yl)phenyl]pyridine-2-carboxamideHuman10573
MAP3K5STE11STE6xihAB(2r)-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}oxane-2-carboxamideHuman12700
MAP3K5STE11STE4bf2AstaurosporineHuman4743
MAP3K5STE11STE5vilA2-methoxy-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}-5-sulfamoylbenzamideHuman9512
MAP3K5STE11STE4bibAA3-cyano-4-(piperidin-4-yloxy)-1h-indole-7-carboxamideHuman4750
MAP3K5STE11STE4bibBA3-cyano-4-(piperidin-4-yloxy)-1h-indole-7-carboxamideHuman4733
MAP3K5STE11STE4bicB-Human4741
MAP3K5STE11STE6oywAA(19s)-19-methyl-16,17,18,19-tetrahydro-8,4-(azeno)[1,2,4]triazolo[4,3-f][1,6,13]benzoxadiazacyclohexadecin-10(9h)-oneHuman11836
MAP3K5STE11STE5uorB6-{[(2s)-4-methylmorpholin-2-yl]methoxy}-2-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}-2,3-dihydro-1h-isoindol-1-oneHuman8108
MAP3K5STE11STE4bieBAn-(2-aminoethyl)-5-{2-methyl-1h-pyrrolo[2,3-b]pyridin-4-yl}thiophene-2-sulfonamideHuman4735
MAP3K5STE11STE6oywDB(19s)-19-methyl-16,17,18,19-tetrahydro-8,4-(azeno)[1,2,4]triazolo[4,3-f][1,6,13]benzoxadiazacyclohexadecin-10(9h)-oneHuman11833
MAP3K5STE11STE6oywBB(19s)-19-methyl-16,17,18,19-tetrahydro-8,4-(azeno)[1,2,4]triazolo[4,3-f][1,6,13]benzoxadiazacyclohexadecin-10(9h)-oneHuman11841
MAP3K5STE11STE6vreBB3-methoxy-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}-1-(pyrazin-2-yl)-1h-pyrazole-4-carboxamideHuman12234
MAP3K5STE11STE5v24BA2-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]-n-(pyridin-2-yl)-1,3-thiazole-4-carboxamideHuman8026
MAP3K5STE11STE3vw6AA4-tert-butyl-n-[6-(1h-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamideHuman4747
MAP3K5STE11STE6e2oA4-(4-cyclopropyl-1h-imidazol-1-yl)-n-[3-(4-cyclopropyl-4h-1,2,4-triazol-3-yl)phenyl]pyridine-2-carboxamideHuman10574
MAP3K5STE11STE6oywCB(19s)-19-methyl-16,17,18,19-tetrahydro-8,4-(azeno)[1,2,4]triazolo[4,3-f][1,6,13]benzoxadiazacyclohexadecin-10(9h)-oneHuman11843
MAP3K5STE11STE5up3A2-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}-2,3-dihydro-1h-isoindol-1-oneHuman8105
MAP3K5STE11STE6oywAB(19s)-19-methyl-16,17,18,19-tetrahydro-8,4-(azeno)[1,2,4]triazolo[4,3-f][1,6,13]benzoxadiazacyclohexadecin-10(9h)-oneHuman11842
MAP3K5STE11STE4bieABn-(2-aminoethyl)-5-{2-methyl-1h-pyrrolo[2,3-b]pyridin-4-yl}thiophene-2-sulfonamideHuman4757
MAP3K5STE11STE5uorA6-{[(2s)-4-methylmorpholin-2-yl]methoxy}-2-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}-2,3-dihydro-1h-isoindol-1-oneHuman8107
MAP3K5STE11STE5uoxA2-(6-{4-[(2r)-1-hydroxypropan-2-yl]-4h-1,2,4-triazol-3-yl}pyridin-2-yl)-6-[(propan-2-yl)oxy]-2,3-dihydro-1h-isoindol-1-oneHuman8109
MAP3K5STE11STE4bieAAn-(2-aminoethyl)-5-{2-methyl-1h-pyrrolo[2,3-b]pyridin-4-yl}thiophene-2-sulfonamideHuman4746
MAP3K5STE11STE6vreBA3-methoxy-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}-1-(pyrazin-2-yl)-1h-pyrazole-4-carboxamideHuman12235
MAP3K5STE11STE5vioD4-methoxy-n~1~-methyl-n~3~-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}benzene-1,3-dicarboxamideHuman9505
MAP3K5STE11STE6e2nAn-[3-(4-cyclopropyl-4h-1,2,4-triazol-3-yl)phenyl][3,4'-bipyridine]-2'-carboxamideHuman10577
MAP3K5STE11STE3vw6AB4-tert-butyl-n-[6-(1h-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamideHuman4752
MAP3K5STE11STE5vioB4-methoxy-n~1~-methyl-n~3~-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}benzene-1,3-dicarboxamideHuman9507
MAP3K5STE11STE5v24AB2-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]-n-(pyridin-2-yl)-1,3-thiazole-4-carboxamideHuman8021
MAP3K5STE11STE3vw6BA4-tert-butyl-n-[6-(1h-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamideHuman4738
MAP3K5STE11STE6oytB5-(4-cyclopropyl-1h-imidazol-1-yl)-2-fluoro-4-methyl-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}benzamideHuman11835
MAP3K5STE11STE6oywCA(19s)-19-methyl-16,17,18,19-tetrahydro-8,4-(azeno)[1,2,4]triazolo[4,3-f][1,6,13]benzoxadiazacyclohexadecin-10(9h)-oneHuman11838
MAP3K5STE11STE6xihBA(2r)-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}oxane-2-carboxamideHuman12702
MAP3K5STE11STE3vw6BB4-tert-butyl-n-[6-(1h-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamideHuman4737
MAP3K5STE11STE6oywDA(19s)-19-methyl-16,17,18,19-tetrahydro-8,4-(azeno)[1,2,4]triazolo[4,3-f][1,6,13]benzoxadiazacyclohexadecin-10(9h)-oneHuman11834
MAP3K5STE11STE4bieBBn-(2-aminoethyl)-5-{2-methyl-1h-pyrrolo[2,3-b]pyridin-4-yl}thiophene-2-sulfonamideHuman4751
MAP3K5STE11STE6e2nBn-[3-(4-cyclopropyl-4h-1,2,4-triazol-3-yl)phenyl][3,4'-bipyridine]-2'-carboxamideHuman10572
MAP3K5STE11STE5vioA4-methoxy-n~1~-methyl-n~3~-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}benzene-1,3-dicarboxamideHuman9510
MAP3K5STE11STE2clqAAstaurosporineHuman4740
MAP3K5STE11STE6oytD5-(4-cyclopropyl-1h-imidazol-1-yl)-2-fluoro-4-methyl-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}benzamideHuman11844
MAP3K5STE11STE4bibBB3-cyano-4-(piperidin-4-yloxy)-1h-indole-7-carboxamideHuman4749
MAP3K5STE11STE4bhnAB4-tert-butyl-n-[6-(1h-pyrazol-4-yl)imidazo[1,2-a]pyridin-2-yl]benzamideHuman4758
MAP3K5STE11STE4bibAB3-cyano-4-(piperidin-4-yloxy)-1h-indole-7-carboxamideHuman4759
MAP3K5STE11STE4bidAB5-[(1r)-2-amino-1-phenylethoxy]-2-(furan-3-yl)-3-{1h-pyrrolo[2,3-b]pyridin-3-yl}pyridineHuman4753
MAP3K5STE11STE6e2mBn-[3-(4-methyl-4h-1,2,4-triazol-3-yl)phenyl]pyridine-2-carboxamideHuman10576
MAP3K5STE11STE5vilD2-methoxy-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}-5-sulfamoylbenzamideHuman9508
MAP3K5STE11STE6vreAA3-methoxy-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}-1-(pyrazin-2-yl)-1h-pyrazole-4-carboxamideHuman12236
MAP3K5STE11STE4bicAn-(2-aminoethyl)-5-{1h-pyrrolo[2,3-b]pyridin-3-yl}thiophene-2-sulfonamideHuman4739
MAP3K5STE11STE5vilC2-methoxy-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}-5-sulfamoylbenzamideHuman9506
MAP3K5STE11STE5v24AA2-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]-n-(pyridin-2-yl)-1,3-thiazole-4-carboxamideHuman8022
MAP3K5STE11STE5uoxB2-(6-{4-[(2r)-1-hydroxypropan-2-yl]-4h-1,2,4-triazol-3-yl}pyridin-2-yl)-6-[(propan-2-yl)oxy]-2,3-dihydro-1h-isoindol-1-oneHuman8106
MAP3K5STE11STE6e2mAn-[3-(4-methyl-4h-1,2,4-triazol-3-yl)phenyl]pyridine-2-carboxamideHuman10575
MAP3K5STE11STE4bidBB5-[(1r)-2-amino-1-phenylethoxy]-2-(furan-3-yl)-3-{1h-pyrrolo[2,3-b]pyridin-3-yl}pyridineHuman4744
MAP3K5STE11STE4bf2BstaurosporineHuman4745
MAP3K5STE11STE4bhnBB4-tert-butyl-n-[6-(1h-pyrazol-4-yl)imidazo[1,2-a]pyridin-2-yl]benzamideHuman4748
MAP3K5STE11STE6xihAA(2r)-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}oxane-2-carboxamideHuman12703
MAP3K5STE11STE6oytC5-(4-cyclopropyl-1h-imidazol-1-yl)-2-fluoro-4-methyl-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}benzamideHuman11840
MAP3K5STE11STE5vilB2-methoxy-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}-5-sulfamoylbenzamideHuman9509
MAP3K5STE11STE6oywBA(19s)-19-methyl-16,17,18,19-tetrahydro-8,4-(azeno)[1,2,4]triazolo[4,3-f][1,6,13]benzoxadiazacyclohexadecin-10(9h)-oneHuman11839
MAP3K5STE11STE2clqBBstaurosporineHuman4732
MAP3K5STE11STE7mu7AA3-methoxy-n-{6-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]pyridin-2-yl}-1-(pyrazin-2-yl)-1h-pyrazole-4-carboxamideHuman14221
MAP3K5STE11STE5v24BB2-[4-(propan-2-yl)-4h-1,2,4-triazol-3-yl]-n-(pyridin-2-yl)-1,3-thiazole-4-carboxamideHuman8023
MAP3K5STE11STE5v19Bn-(1-ethyl-1h-pyrazol-4-yl)furan-3-carboxamideHuman8024
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