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Search results (109 entries covering 29 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetails File
MAPKAPK2MAPKAPKCAMK8xx1AA-Human15257
MAPKAPK2MAPKAPKCAMK8xx1AB-Human15256
MAPKAPK2MAPKAPKCAMK3r2bK-Human1293
MAPKAPK2MAPKAPKCAMK3r2bA2'-[2-(1,3-benzodioxol-5-yl)pyrimidin-4-yl]-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'h)-oneHuman1287
MAPKAPK2MAPKAPKCAMK3kc3Dn~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamineHuman1288
MAPKAPK2MAPKAPKCAMK3r2bH-Human1348
MAPKAPK2MAPKAPKCAMK3gokC2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1350
MAPKAPK2MAPKAPKCAMK3wi6En-[(3s)-piperidin-3-yl]-7,8-dihydro-6h-pyrazolo[1,5-a]pyrrolo[3,2-e]pyrimidin-5-amineHuman1323
MAPKAPK2MAPKAPKCAMK2onlD-Human1345
MAPKAPK2MAPKAPKCAMK3a2cCn~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamineHuman1328
MAPKAPK2MAPKAPKCAMK2jbpG2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1339
MAPKAPK2MAPKAPKCAMK2pzyB(4r)-n-[4-({[2-(dimethylamino)ethyl]amino}carbonyl)-1,3-thiazol-2-yl]-4-methyl-1-oxo-2,3,4,9-tetrahydro-1h-beta-carboline-6-carboxamideHuman1307
MAPKAPK2MAPKAPKCAMK3r2bG-Human1369
MAPKAPK2MAPKAPKCAMK3r2bC-Human1368
MAPKAPK2MAPKAPKCAMK3r2bE-Human1286
MAPKAPK2MAPKAPKCAMK2jbpB2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1320
MAPKAPK2MAPKAPKCAMK3a2cBn~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamineHuman1332
MAPKAPK2MAPKAPKCAMK3gokF2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1362
MAPKAPK2MAPKAPKCAMK2pzyA(4r)-n-[4-({[2-(dimethylamino)ethyl]amino}carbonyl)-1,3-thiazol-2-yl]-4-methyl-1-oxo-2,3,4,9-tetrahydro-1h-beta-carboline-6-carboxamideHuman1314
MAPKAPK2MAPKAPKCAMK2jbpH2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1326
MAPKAPK2MAPKAPKCAMK6tcaEB-Human12503
MAPKAPK2MAPKAPKCAMK3r2bB2'-[2-(1,3-benzodioxol-5-yl)pyrimidin-4-yl]-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'h)-oneHuman1329
MAPKAPK2MAPKAPKCAMK3r2yA2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1361
MAPKAPK2MAPKAPKCAMK1ny3Aadenosine-5'-diphosphateHuman1318
MAPKAPK2MAPKAPKCAMK1kwpA-Human1280
MAPKAPK2MAPKAPKCAMK3ka0A6-{5-[(2-aminopyrimidin-4-yl)amino]-2-hydroxyphenyl}-n-methylidene-1-benzothiophene-2-carboxamideHuman1290
MAPKAPK2MAPKAPKCAMK2p3gX2-[2-(2-fluorophenyl)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1349
MAPKAPK2MAPKAPKCAMK2jbpA2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1366
MAPKAPK2MAPKAPKCAMK2jbpI2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1364
MAPKAPK2MAPKAPKCAMK3kc3Cn~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamineHuman1303
MAPKAPK2MAPKAPKCAMK1nxkAstaurosporineHuman1342
MAPKAPK2MAPKAPKCAMK2jbpK2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1363
MAPKAPK2MAPKAPKCAMK2onlC-Human1306
MAPKAPK2MAPKAPKCAMK3r2bD-Human1337
MAPKAPK2MAPKAPKCAMK6t8xA(10r)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8h-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-oneHuman13548
MAPKAPK2MAPKAPKCAMK3wi6Dn-[(3s)-piperidin-3-yl]-7,8-dihydro-6h-pyrazolo[1,5-a]pyrrolo[3,2-e]pyrimidin-5-amineHuman1340
MAPKAPK2MAPKAPKCAMK3gokJ2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1319
MAPKAPK2MAPKAPKCAMK3kc3In~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamineHuman1354
MAPKAPK2MAPKAPKCAMK6tcaEA-Human12500
MAPKAPK2MAPKAPKCAMK2jbpL2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1283
MAPKAPK2MAPKAPKCAMK3kgaAA6-{3-amino-1-[3-(1h-indol-6-yl)phenyl]-1h-pyrazol-4-yl}-3,4-dihydroisoquinolin-1(2h)-oneHuman9476
MAPKAPK2MAPKAPKCAMK3gokH2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1338
MAPKAPK2MAPKAPKCAMK3kc3Hn~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamineHuman1291
MAPKAPK2MAPKAPKCAMK3gokI2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1305
MAPKAPK2MAPKAPKCAMK3kc3An~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamineHuman1289
MAPKAPK2MAPKAPKCAMK3a2cAn~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamineHuman1330
MAPKAPK2MAPKAPKCAMK3wi6An-[(3s)-piperidin-3-yl]-7,8-dihydro-6h-pyrazolo[1,5-a]pyrrolo[3,2-e]pyrimidin-5-amineHuman1308
MAPKAPK2MAPKAPKCAMK3gokL2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1365
MAPKAPK2MAPKAPKCAMK1nxkCstaurosporineHuman1312
MAPKAPK2MAPKAPKCAMK1nxkDstaurosporineHuman1334
MAPKAPK2MAPKAPKCAMK3m2wAA2'-(2-fluorophenyl)-1-methyl-6',8',9',11'-tetrahydrospiro[azetidine-3,10'-pyrido[3',4':4,5]pyrrolo[2,3-f]isoquinolin]-7'(5'h)-oneHuman9474
MAPKAPK2MAPKAPKCAMK6tcaGB-Human12501
MAPKAPK2MAPKAPKCAMK3fykX(3r)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5h-[1]benzothieno[3,2-e][1,4]diazepin-5-oneHuman1297
MAPKAPK2MAPKAPKCAMK3a2cHn~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamineHuman1325
MAPKAPK2MAPKAPKCAMK2jboA2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1333
MAPKAPK2MAPKAPKCAMK6tcaAA-Human12502
MAPKAPK2MAPKAPKCAMK6tcaCA-Human12504
MAPKAPK2MAPKAPKCAMK3r30AB1-(2-aminoethyl)-3-[2-(quinolin-3-yl)pyridin-4-yl]-1h-pyrazole-5-carboxylic acidHuman1309
MAPKAPK2MAPKAPKCAMK3gokA2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1281
MAPKAPK2MAPKAPKCAMK3gokD2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1284
MAPKAPK2MAPKAPKCAMK6tcaGA-Human12505
MAPKAPK2MAPKAPKCAMK3a2cKn~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamineHuman1360
MAPKAPK2MAPKAPKCAMK3gokG2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1351
MAPKAPK2MAPKAPKCAMK3a2cLn~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamineHuman1301
MAPKAPK2MAPKAPKCAMK3fyjX(10r)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8h-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-oneHuman1336
MAPKAPK2MAPKAPKCAMK3wi6Fn-[(3s)-piperidin-3-yl]-7,8-dihydro-6h-pyrazolo[1,5-a]pyrrolo[3,2-e]pyrimidin-5-amineHuman1313
MAPKAPK2MAPKAPKCAMK2jbpC2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1344
MAPKAPK2MAPKAPKCAMK2jbpD2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1327
MAPKAPK2MAPKAPKCAMK3r2bL-Human1295
MAPKAPK2MAPKAPKCAMK2pzyD-Human1357
MAPKAPK2MAPKAPKCAMK3m42A2-[5-(2-methoxyethoxy)pyridin-3-yl]-8,9,10,11-tetrahydro-7h-pyrido[3',4':4,5]pyrrolo[2,3-f]isoquinolin-7-oneHuman9475
MAPKAPK2MAPKAPKCAMK3a2cIn~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamineHuman1311
MAPKAPK2MAPKAPKCAMK6tcaCB-Human12506
MAPKAPK2MAPKAPKCAMK3kc3En~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamineHuman1285
MAPKAPK2MAPKAPKCAMK1kwpB-Human1296
MAPKAPK2MAPKAPKCAMK3kc3Ln~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamineHuman1324
MAPKAPK2MAPKAPKCAMK3a2cGn~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamineHuman1343
MAPKAPK2MAPKAPKCAMK3kgaAB6-{3-amino-1-[3-(1h-indol-6-yl)phenyl]-1h-pyrazol-4-yl}-3,4-dihydroisoquinolin-1(2h)-oneHuman9477
MAPKAPK2MAPKAPKCAMK3kc3G-Human1356
MAPKAPK2MAPKAPKCAMK3r2bJ-Human1331
MAPKAPK2MAPKAPKCAMK3gokK2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1299
MAPKAPK2MAPKAPKCAMK6tcaAB-Human12507
MAPKAPK2MAPKAPKCAMK9r59A5-[3-[bis(oxidanyl)-$l^{3}-sulfanyl]oxy-4-chloranyl-phenyl]-~{n}-(4-piperazin-1-ylphenyl)-~{n}-(pyridin-2-ylmethyl)furan-2-carboxamideHuman16033
MAPKAPK2MAPKAPKCAMK3r30AA1-(2-aminoethyl)-3-[2-(quinolin-3-yl)pyridin-4-yl]-1h-pyrazole-5-carboxylic acidHuman1352
MAPKAPK2MAPKAPKCAMK3wi6Bn-[(3s)-piperidin-3-yl]-7,8-dihydro-6h-pyrazolo[1,5-a]pyrrolo[3,2-e]pyrimidin-5-amineHuman1282
MAPKAPK2MAPKAPKCAMK4tyhAA-Human1302
MAPKAPK2MAPKAPKCAMK3gokB2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1304
MAPKAPK2MAPKAPKCAMK8xu4A-Human15173
MAPKAPK2MAPKAPKCAMK3a2cFn~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamineHuman1355
MAPKAPK2MAPKAPKCAMK2ozaA-Human1310
MAPKAPK2MAPKAPKCAMK3kc3Bn~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamineHuman1298
MAPKAPK2MAPKAPKCAMK3r2bF-Human1321
MAPKAPK2MAPKAPKCAMK3wi6Cn-[(3s)-piperidin-3-yl]-7,8-dihydro-6h-pyrazolo[1,5-a]pyrrolo[3,2-e]pyrimidin-5-amineHuman1346
MAPKAPK2MAPKAPKCAMK3a2cEn~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamineHuman1315
MAPKAPK2MAPKAPKCAMK2jbpF2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1335
MAPKAPK2MAPKAPKCAMK3fpmA3-{[(1r)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dioneHuman1367
MAPKAPK2MAPKAPKCAMK2jbpE2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1358
MAPKAPK2MAPKAPKCAMK3m2wAB2'-(2-fluorophenyl)-1-methyl-6',8',9',11'-tetrahydrospiro[azetidine-3,10'-pyrido[3',4':4,5]pyrrolo[2,3-f]isoquinolin]-7'(5'h)-oneHuman9473
MAPKAPK2MAPKAPKCAMK4tyhAB-Human1322
MAPKAPK2MAPKAPKCAMK3gokE2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-oneHuman1300
MAPKAPK2MAPKAPKCAMK3a2cDn~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamineHuman1316
MAPKAPK2MAPKAPKCAMK3kc3Kn~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamineHuman1317
MAPKAPK2MAPKAPKCAMK3kc3Jn~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamineHuman1347
MAPKAPK2MAPKAPKCAMK2jbpJ-Human1359
MAPKAPK2MAPKAPKCAMK2pzyCstaurosporineHuman1279
MAPKAPK2MAPKAPKCAMK3kc3Fn~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamineHuman1341
MAPKAPK2MAPKAPKCAMK3a2cJn~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamineHuman1353
MAPKAPK2MAPKAPKCAMK1nxkBstaurosporineHuman1292
MAPKAPK2MAPKAPKCAMK3r2bI-Human1294
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