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Search results (88 entries covering 34 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetails File
MELKCAMKLCAMK9f31An-[4-(1h-indazol-5-yl)phenyl]propanamideHuman15787
MELKCAMKLCAMK5m5aAAk-252aHuman8735
MELKCAMKLCAMK5maiAA3-[(3~{z})-3-[[[4-[(dimethylamino)methyl]phenyl]amino]-phenyl-methylidene]-2-oxidanylidene-1~{h}-indol-6-yl]-~{n}-ethyl-prop-2-ynamideHuman8728
MELKCAMKLCAMK5twyB2-(benzyloxy)-4-(1h-pyrazol-4-yl)-n-(2,3,4,5-tetrahydro-1h-3-benzazepin-7-yl)benzamideHuman8669
MELKCAMKLCAMK4d2pDA7-({4-[(3-hydroxy-5-methoxyphenyl)amino]benzoyl}amino)-1,2,3,4-tetrahydroisoquinoliniumHuman2486
MELKCAMKLCAMK6vxrAB(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-5,8-di(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHuman12644
MELKCAMKLCAMK5k00AA4-{2-[(3-methoxyphenyl)amino]-4-[(piperidin-4-yl)methoxy]pyrimidin-5-yl}-n-[2-oxo-2-(phenylamino)ethyl]benzamideHuman7497
MELKCAMKLCAMK4d2wAA4-bromo-n-(2,3,4,5-tetrahydro-1h-3-benzazepin-7-yl)benzamideHuman2515
MELKCAMKLCAMK4umpCA3-(isoquinolin-7-yl)prop-2-yn-1-olHuman2479
MELKCAMKLCAMK4d2vDA7-{[2-methoxy-4-(1h-pyrazol-4-yl)benzoyl]amino}-2,3,4,5-tetrahydro-1h-3-benzazepiniumHuman2502
MELKCAMKLCAMK6vxrAA(7r)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-5,8-di(prop-2-yn-1-yl)-7,8-dihydropteridin-6(5h)-oneHuman12645
MELKCAMKLCAMK4d2pAA7-({4-[(3-hydroxy-5-methoxyphenyl)amino]benzoyl}amino)-1,2,3,4-tetrahydroisoquinoliniumHuman2513
MELKCAMKLCAMK4d2pCB7-({4-[(3-hydroxy-5-methoxyphenyl)amino]benzoyl}amino)-1,2,3,4-tetrahydroisoquinoliniumHuman2501
MELKCAMKLCAMK4umpDB3-(isoquinolin-7-yl)prop-2-yn-1-olHuman2525
MELKCAMKLCAMK5twzA7-{[2-methoxy-4-(1h-pyrazol-4-yl)benzoyl]amino}-2,3,4,5-tetrahydro-1h-3-benzazepiniumHuman8675
MELKCAMKLCAMK5m5aABk-252aHuman8733
MELKCAMKLCAMK4umpBB3-(isoquinolin-7-yl)prop-2-yn-1-olHuman2504
MELKCAMKLCAMK5tx3B7-[(1s)-4-hydroxy-2,3-dihydro-1h-inden-1-yl]-5,5-dimethyl-2-({3-[(pyrrolidin-1-yl)methyl]phenyl}amino)-5,7-dihydro-6h-pyrrolo[2,3-d]pyrimidin-6-oneHuman8674
MELKCAMKLCAMK4d2vDB7-{[2-methoxy-4-(1h-pyrazol-4-yl)benzoyl]amino}-2,3,4,5-tetrahydro-1h-3-benzazepiniumHuman2506
MELKCAMKLCAMK4d2vAB7-{[2-methoxy-4-(1h-pyrazol-4-yl)benzoyl]amino}-2,3,4,5-tetrahydro-1h-3-benzazepiniumHuman2522
MELKCAMKLCAMK4umqAB3-{5-[(3-hydroxy-5-methoxyphenyl)amino]-2-(phenylcarbamoyl)phenoxy}propan-1-aminiumHuman2523
MELKCAMKLCAMK5tvtA9-(3,5-dichloro-4-hydroxyphenyl)-1-{trans-4-[(dimethylamino)methyl]cyclohexyl}-3-methyl-3,4-dihydropyrimido[5,4-c][1,5]naphthyridin-2(1h)-oneHuman8667
MELKCAMKLCAMK4d2wCB4-bromo-n-(2,3,4,5-tetrahydro-1h-3-benzazepin-7-yl)benzamideHuman2503
MELKCAMKLCAMK6gvxAB6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidineHuman11139
MELKCAMKLCAMK5ihaAA1-methyl-4-(4-{4-[3-(2-methylpropoxy)pyridin-4-yl]-1h-pyrazol-1-yl}phenyl)piperazineHuman6663
MELKCAMKLCAMK5twlA9-(3,5-dichloro-4-hydroxyphenyl)-1-{trans-4-[(dimethylamino)methyl]cyclohexyl}-3,4-dihydropyrimido[5,4-c]quinolin-2(1h)-oneHuman8668
MELKCAMKLCAMK4d2tAB3-[2-(phenylcarbamoyl)-5-(1h-pyrazol-4-yl)phenoxy]propan-1-aminiumHuman2489
MELKCAMKLCAMK5magAApf-3758309Human8736
MELKCAMKLCAMK4bkyAB3'-{[(4-bromo-1-methyl-1h-pyrrol-2-yl)carbonyl]amino}-n-[(1s)-1-phenyl-2-(pyrrolidin-1-yl)ethyl]-1',4'-dihydro-5'h-spiro[cyclopropane-1,6'-pyrrolo[3,4-c]pyrazole]-5'-carboxamideHuman2490
MELKCAMKLCAMK4d2vBB7-{[2-methoxy-4-(1h-pyrazol-4-yl)benzoyl]amino}-2,3,4,5-tetrahydro-1h-3-benzazepiniumHuman2507
MELKCAMKLCAMK4bkzABn-(3-aminopropyl)-8-[(3-fluorophenyl)amino]-2,4,5,7-tetrahydropyrazolo[3,4-e]indazole-3-carboxamideHuman2484
MELKCAMKLCAMK4umpAA3-(isoquinolin-7-yl)prop-2-yn-1-olHuman2497
MELKCAMKLCAMK5mafAmethyl (3z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1h-indole-6-carboxylateHuman8732
MELKCAMKLCAMK5ihcAA4-[1-(2-fluorophenyl)-1h-pyrazol-4-yl]-3-[(piperidin-4-yl)methoxy]pyridineHuman6660
MELKCAMKLCAMK4ixpA-Human2528
MELKCAMKLCAMK4d2wDB4-bromo-n-(2,3,4,5-tetrahydro-1h-3-benzazepin-7-yl)benzamideHuman2495
MELKCAMKLCAMK5ih8An-[(pyridin-2-yl)methyl]-4-[4-(pyridin-4-yl)-1h-pyrazol-1-yl]benzamideHuman6661
MELKCAMKLCAMK4d2tBB3-[2-(phenylcarbamoyl)-5-(1h-pyrazol-4-yl)phenoxy]propan-1-aminiumHuman2512
MELKCAMKLCAMK6gvxBB6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidineHuman11138
MELKCAMKLCAMK5ih9AB1-methyl-4-[4-(4-{3-[(piperidin-4-yl)methoxy]pyridin-4-yl}-1h-pyrazol-1-yl)phenyl]piperazineHuman6657
MELKCAMKLCAMK4bkzAAn-(3-aminopropyl)-8-[(3-fluorophenyl)amino]-2,4,5,7-tetrahydropyrazolo[3,4-e]indazole-3-carboxamideHuman2505
MELKCAMKLCAMK5mahAA~{n}-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamideHuman8729
MELKCAMKLCAMK4d2wBB4-bromo-n-(2,3,4,5-tetrahydro-1h-3-benzazepin-7-yl)benzamideHuman2482
MELKCAMKLCAMK4umpCB3-(isoquinolin-7-yl)prop-2-yn-1-olHuman2508
MELKCAMKLCAMK4d2pCA7-({4-[(3-hydroxy-5-methoxyphenyl)amino]benzoyl}amino)-1,2,3,4-tetrahydroisoquinoliniumHuman2496
MELKCAMKLCAMK5ihaAB1-methyl-4-(4-{4-[3-(2-methylpropoxy)pyridin-4-yl]-1h-pyrazol-1-yl}phenyl)piperazineHuman6658
MELKCAMKLCAMK4umrA4-fluoro-n-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamideHuman2521
MELKCAMKLCAMK6gvxAA6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidineHuman11137
MELKCAMKLCAMK5twuB-Human8672
MELKCAMKLCAMK4d2tBA3-[2-(phenylcarbamoyl)-5-(1h-pyrazol-4-yl)phenoxy]propan-1-aminiumHuman2520
MELKCAMKLCAMK4d2tAA3-[2-(phenylcarbamoyl)-5-(1h-pyrazol-4-yl)phenoxy]propan-1-aminiumHuman2487
MELKCAMKLCAMK4d2pDB7-({4-[(3-hydroxy-5-methoxyphenyl)amino]benzoyl}amino)-1,2,3,4-tetrahydroisoquinoliniumHuman2518
MELKCAMKLCAMK4umpDA3-(isoquinolin-7-yl)prop-2-yn-1-olHuman2516
MELKCAMKLCAMK4d2wCA4-bromo-n-(2,3,4,5-tetrahydro-1h-3-benzazepin-7-yl)benzamideHuman2527
MELKCAMKLCAMK5k00AB4-{2-[(3-methoxyphenyl)amino]-4-[(piperidin-4-yl)methoxy]pyrimidin-5-yl}-n-[2-oxo-2-(phenylamino)ethyl]benzamideHuman7498
MELKCAMKLCAMK4d2wDA4-bromo-n-(2,3,4,5-tetrahydro-1h-3-benzazepin-7-yl)benzamideHuman2481
MELKCAMKLCAMK4bl1ABphosphoaminophosphonic acid-adenylate esterHuman2519
MELKCAMKLCAMK5ihcAB4-[1-(2-fluorophenyl)-1h-pyrazol-4-yl]-3-[(piperidin-4-yl)methoxy]pyridineHuman6662
MELKCAMKLCAMK4d2tDA3-[2-(phenylcarbamoyl)-5-(1h-pyrazol-4-yl)phenoxy]propan-1-aminiumHuman2530
MELKCAMKLCAMK4d2vAA7-{[2-methoxy-4-(1h-pyrazol-4-yl)benzoyl]amino}-2,3,4,5-tetrahydro-1h-3-benzazepiniumHuman2493
MELKCAMKLCAMK4d2pBB7-({4-[(3-hydroxy-5-methoxyphenyl)amino]benzoyl}amino)-1,2,3,4-tetrahydroisoquinoliniumHuman2498
MELKCAMKLCAMK4d2wBA4-bromo-n-(2,3,4,5-tetrahydro-1h-3-benzazepin-7-yl)benzamideHuman2500
MELKCAMKLCAMK5ih9AA1-methyl-4-[4-(4-{3-[(piperidin-4-yl)methoxy]pyridin-4-yl}-1h-pyrazol-1-yl)phenyl]piperazineHuman6659
MELKCAMKLCAMK4umuA(2-ethoxy-4-{[3-(isoquinolin-7-yl)prop-2-yn-1-yl]oxy}phenyl)methanaminiumHuman2517
MELKCAMKLCAMK4d2pBA7-({4-[(3-hydroxy-5-methoxyphenyl)amino]benzoyl}amino)-1,2,3,4-tetrahydroisoquinoliniumHuman2494
MELKCAMKLCAMK5maiAB3-[(3~{z})-3-[[[4-[(dimethylamino)methyl]phenyl]amino]-phenyl-methylidene]-2-oxidanylidene-1~{h}-indol-6-yl]-~{n}-ethyl-prop-2-ynamideHuman8730
MELKCAMKLCAMK6gvxBA6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidineHuman11136
MELKCAMKLCAMK5twyA2-(benzyloxy)-4-(1h-pyrazol-4-yl)-n-(2,3,4,5-tetrahydro-1h-3-benzazepin-7-yl)benzamideHuman8671
MELKCAMKLCAMK4d2vBA7-{[2-methoxy-4-(1h-pyrazol-4-yl)benzoyl]amino}-2,3,4,5-tetrahydro-1h-3-benzazepiniumHuman2483
MELKCAMKLCAMK4umqAA3-{5-[(3-hydroxy-5-methoxyphenyl)amino]-2-(phenylcarbamoyl)phenoxy}propan-1-aminiumHuman2488
MELKCAMKLCAMK4d2tCA3-[2-(phenylcarbamoyl)-5-(1h-pyrazol-4-yl)phenoxy]propan-1-aminiumHuman2491
MELKCAMKLCAMK5mahAB~{n}-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamideHuman8734
MELKCAMKLCAMK4bkyAA3'-{[(4-bromo-1-methyl-1h-pyrrol-2-yl)carbonyl]amino}-n-[(1s)-1-phenyl-2-(pyrrolidin-1-yl)ethyl]-1',4'-dihydro-5'h-spiro[cyclopropane-1,6'-pyrrolo[3,4-c]pyrazole]-5'-carboxamideHuman2480
MELKCAMKLCAMK4d2tCB3-[2-(phenylcarbamoyl)-5-(1h-pyrazol-4-yl)phenoxy]propan-1-aminiumHuman2526
MELKCAMKLCAMK4d2wAB4-bromo-n-(2,3,4,5-tetrahydro-1h-3-benzazepin-7-yl)benzamideHuman2509
MELKCAMKLCAMK4umpAB3-(isoquinolin-7-yl)prop-2-yn-1-olHuman2485
MELKCAMKLCAMK5twuA-Human8670
MELKCAMKLCAMK5tx3A7-[(1s)-4-hydroxy-2,3-dihydro-1h-inden-1-yl]-5,5-dimethyl-2-({3-[(pyrrolidin-1-yl)methyl]phenyl}amino)-5,7-dihydro-6h-pyrrolo[2,3-d]pyrimidin-6-oneHuman8673
MELKCAMKLCAMK4bl1AAphosphoaminophosphonic acid-adenylate esterHuman2514
MELKCAMKLCAMK4d2vCB7-{[2-methoxy-4-(1h-pyrazol-4-yl)benzoyl]amino}-2,3,4,5-tetrahydro-1h-3-benzazepiniumHuman2492
MELKCAMKLCAMK4umtA1-(4-{[3-(isoquinolin-7-yl)prop-2-yn-1-yl]oxy}-2-methoxybenzyl)piperazinediiumHuman2510
MELKCAMKLCAMK5magABpf-3758309Human8731
MELKCAMKLCAMK4umpBA3-(isoquinolin-7-yl)prop-2-yn-1-olHuman2524
MELKCAMKLCAMK4d2vCA7-{[2-methoxy-4-(1h-pyrazol-4-yl)benzoyl]amino}-2,3,4,5-tetrahydro-1h-3-benzazepiniumHuman2529
MELKCAMKLCAMK4d2pAB7-({4-[(3-hydroxy-5-methoxyphenyl)amino]benzoyl}amino)-1,2,3,4-tetrahydroisoquinoliniumHuman2499
MELKCAMKLCAMK4d2tDB3-[2-(phenylcarbamoyl)-5-(1h-pyrazol-4-yl)phenoxy]propan-1-aminiumHuman2511
Melk (MELK)CAMKLCAMK4cqgA1-[6-(3,5-dichloro-4-hydroxyphenyl)-4-({trans-4-[(dimethylamino)methyl]cyclohexyl}amino)-1,5-naphthyridin-3-yl]ethanoneMouse6865
Melk (MELK)CAMKLCAMK4bfmAphosphoaminophosphonic acid-adenylate esterMouse5798
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