| PAK1 | STE20 | STE | 1yhw | A | | - | Human | 160 | |
| PAK1 | STE20 | STE | 3fxz | A | A | octahedral ru-pyridocarbazole | Human | 7198 | |
| PAK1 | STE20 | STE | 4daw | A | B | [1,3-dioxo-6-(pyridin-2-yl-kappan)-2,3-dihydro-1h-isoindol-5-yl-kappac~5~][(thioxomethylidene)azanido-kappan](1,4,7-trithionane-kappa~3~s~1~,s~4~,s~7~)ruthenium | Human | 7199 | |
| PAK1 | STE20 | STE | 4zji | C | B | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | Human | 152 | |
| PAK1 | STE20 | STE | 4o0r | A | | pf-3758309 | Human | 171 | |
| PAK1 | STE20 | STE | 3fxz | A | B | octahedral ru-pyridocarbazole | Human | 7200 | |
| PAK1 | STE20 | STE | 3q4z | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 166 | |
| PAK1 | STE20 | STE | 4zlo | B | B | - | Human | 170 | |
| PAK1 | STE20 | STE | 4zy6 | B | A | n~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | 156 | |
| PAK1 | STE20 | STE | 3q53 | A | | adenosine-5'-triphosphate | Human | 165 | |
| PAK1 | STE20 | STE | 4zjj | D | A | (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide | Human | 169 | |
| PAK1 | STE20 | STE | 8x5z | A | B | - | Human | 15048 | |
| PAK1 | STE20 | STE | 4zy6 | A | B | n~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | 173 | |
| PAK1 | STE20 | STE | 5kbq | B | | - | Human | 7082 | |
| PAK1 | STE20 | STE | 4zy4 | A | | 2-(4-aminopiperidin-1-yl)-n-(5-cyclopropyl-1h-pyrazol-3-yl)thieno[3,2-d]pyrimidin-4-amine | Human | 187 | |
| PAK1 | STE20 | STE | 8x5z | A | A | - | Human | 15049 | |
| PAK1 | STE20 | STE | 4daw | A | A | [1,3-dioxo-6-(pyridin-2-yl-kappan)-2,3-dihydro-1h-isoindol-5-yl-kappac~5~][(thioxomethylidene)azanido-kappan](1,4,7-trithionane-kappa~3~s~1~,s~4~,s~7~)ruthenium | Human | 7201 | |
| PAK1 | STE20 | STE | 4o0t | A | | 1-({1-(2-aminopyrimidin-4-yl)-2-[(2-methoxyethyl)amino]-1h-benzimidazol-6-yl}ethynyl)cyclohexanol | Human | 143 | |
| PAK1 | STE20 | STE | 5dfp | A | B | 6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-{[2-(1-methylpiperidin-4-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 6363 | |
| PAK1 | STE20 | STE | 4zy5 | A | | n~2~-[(trans-4-aminocyclohexyl)methyl]-n~4~-(3-cyclopropyl-1h-pyrazol-5-yl)pyrimidine-2,4-diamine | Human | 155 | |
| PAK1 | STE20 | STE | 4p90 | B | | [2-chloro-5-(hydroxymethyl)phenyl]{5-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]-1h-pyrrolo[2,3-b]pyridin-3-yl}methanone | Human | 151 | |
| PAK1 | STE20 | STE | 5dew | B | | 8-[(trans-4-aminocyclohexyl)methyl]-6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(ethylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 7409 | |
| PAK1 | STE20 | STE | 4zy6 | A | A | n~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | 138 | |
| PAK1 | STE20 | STE | 3q4z | B | B | - | Human | 183 | |
| PAK1 | STE20 | STE | 4zjj | A | A | (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide | Human | 157 | |
| PAK1 | STE20 | STE | 1yhv | A | | - | Human | 177 | |
| PAK1 | STE20 | STE | 4zy5 | B | | n~2~-[(trans-4-aminocyclohexyl)methyl]-n~4~-(3-cyclopropyl-1h-pyrazol-5-yl)pyrimidine-2,4-diamine | Human | 163 | |
| PAK1 | STE20 | STE | 7vto | A | A | 4-[(7-oxo-7h-thiazolo[5,4-e]indol-8-ylmethyl)-amino]-n-pyridin-2-yl-benzenesulfonamide | Human | 14483 | |
| PAK1 | STE20 | STE | 3q52 | A | | - | Human | 146 | |
| PAK1 | STE20 | STE | 4zji | B | A | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | Human | 168 | |
| PAK1 | STE20 | STE | 7vto | A | B | 4-[(7-oxo-7h-thiazolo[5,4-e]indol-8-ylmethyl)-amino]-n-pyridin-2-yl-benzenesulfonamide | Human | 14484 | |
| PAK1 | STE20 | STE | 9nbx | A | | (6m)-8-(3-aminopropyl)-6-(4-butoxy-2-methylphenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 15745 | |
| PAK1 | STE20 | STE | 4p90 | A | | [2-chloro-5-(hydroxymethyl)phenyl]{5-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]-1h-pyrrolo[2,3-b]pyridin-3-yl}methanone | Human | 164 | |
| PAK1 | STE20 | STE | 4zji | D | B | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | Human | 150 | |
| PAK1 | STE20 | STE | 5dew | A | | 8-[(trans-4-aminocyclohexyl)methyl]-6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(ethylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 7408 | |
| PAK1 | STE20 | STE | 4zlo | A | A | 2,8-difluoro-11-(4-methylpiperazin-1-yl)-5h-dibenzo[b,e][1,4]diazepine | Human | 142 | |
| PAK1 | STE20 | STE | 9n4u | A | | (3m)-3-[(4p)-2-chloro-4-(6-methylpyridin-2-yl)phenyl]-1-{2-[2-(dimethylamino)ethoxy]ethyl}-1,6-naphthyridin-2(1h)-one | Human | 15744 | |
| PAK1 | STE20 | STE | 4zjj | A | B | (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide | Human | 153 | |
| PAK1 | STE20 | STE | 6b16 | A | | n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)-n~2~-[(1s)-1-(1h-pyrrolo[3,2-b]pyridin-5-yl)ethyl]pyrimidine-2,4-diamine | Human | 8574 | |
| PAK1 | STE20 | STE | 4zji | D | A | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | Human | 139 | |
| PAK1 | STE20 | STE | 4zji | B | B | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | Human | 185 | |
| PAK1 | STE20 | STE | 4zlo | A | B | 2,8-difluoro-11-(4-methylpiperazin-1-yl)-5h-dibenzo[b,e][1,4]diazepine | Human | 181 | |
| PAK1 | STE20 | STE | 4zji | C | A | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | Human | 167 | |
| PAK1 | STE20 | STE | 5dey | A | | 8-[(trans-5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 6364 | |
| PAK1 | STE20 | STE | 4zji | A | B | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | Human | 175 | |
| PAK1 | STE20 | STE | 3q4z | B | A | - | Human | 144 | |
| PAK1 | STE20 | STE | 5ime | A | | 8-(3-aminopropyl)-6-[2-chloro-4-(3-methyl-2-oxopyrazin-1(2h)-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 6644 | |
| PAK1 | STE20 | STE | 4zji | A | A | 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine | Human | 159 | |
| PAK1 | STE20 | STE | 4zjj | B | A | (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide | Human | 176 | |
| PAK1 | STE20 | STE | 1f3m | D | | - | Human | 158 | |
| PAK1 | STE20 | STE | 5dfp | A | A | 6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-{[2-(1-methylpiperidin-4-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 6366 | |
| PAK1 | STE20 | STE | 5kbr | A | | (4-chlorophenyl)-[5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]methanone | Human | 7080 | |
| PAK1 | STE20 | STE | 4zjj | B | B | (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide | Human | 137 | |
| PAK1 | STE20 | STE | 4eqc | A | B | 6-[2-chloro-4-(1,3-thiazol-5-yl)phenyl]-8-ethyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 147 | |
| PAK1 | STE20 | STE | 4zy4 | B | | 2-(4-aminopiperidin-1-yl)-n-(5-cyclopropyl-1h-pyrazol-3-yl)thieno[3,2-d]pyrimidin-4-amine | Human | 154 | |
| PAK1 | STE20 | STE | 1f3m | C | | - | Human | 161 | |
| PAK1 | STE20 | STE | 5dey | B | | 8-[(trans-5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 6365 | |
| PAK1 | STE20 | STE | 5kbr | B | | (4-chlorophenyl)-[5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]methanone | Human | 7079 | |
| PAK1 | STE20 | STE | 6b16 | B | | n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)-n~2~-[(1s)-1-(1h-pyrrolo[3,2-b]pyridin-5-yl)ethyl]pyrimidine-2,4-diamine | Human | 8575 | |
| PAK1 | STE20 | STE | 4o0t | B | | - | Human | 141 | |
| PAK1 | STE20 | STE | 5ime | B | | 8-(3-aminopropyl)-6-[2-chloro-4-(3-methyl-2-oxopyrazin-1(2h)-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 6643 | |
| PAK1 | STE20 | STE | 3q4z | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 174 | |
| PAK1 | STE20 | STE | 3fy0 | A | | ruthenium pyridocarbazole | Human | 7202 | |
| PAK1 | STE20 | STE | 4zjj | D | B | (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide | Human | 162 | |
| PAK1 | STE20 | STE | 4zy6 | B | B | n~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | 184 | |
| PAK1 | STE20 | STE | 2hy8 | 1 | | (5s,6r,7r,9r)-12-hydroxy-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9-tetrahydro-5h,14h-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-one | Human | 172 | |
| PAK1 | STE20 | STE | 4zlo | B | A | - | Human | 188 | |
| PAK1 | STE20 | STE | 4zjj | C | A | (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide | Human | 182 | |
| PAK1 | STE20 | STE | 5kbq | A | | [4-methyl-3-[methyl-[2-[(3-methylsulfonyl-5-morpholin-4-yl-phenyl)amino]pyrimidin-4-yl]amino]phenyl]methanol | Human | 7081 | |
| PAK1 | STE20 | STE | 4eqc | A | A | 6-[2-chloro-4-(1,3-thiazol-5-yl)phenyl]-8-ethyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 180 | |
| PAK1 | STE20 | STE | 4o0r | B | | - | Human | 145 | |
| PAK1 | STE20 | STE | 4zjj | C | B | (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro-dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide | Human | 178 | |
