Search results (17 entries covering 14 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
| PTK2B (PYK2) | FAK | TK | 3h3c | A | 4-{[4-{[(1r,2r)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-n-methylbenzenesulfonamide | Human | 96 | |||
| PTK2B (PYK2) | FAK | TK | 8ygx | A | B | - | Human | 15244 | ||
| PTK2B (PYK2) | FAK | TK | 8ygx | A | A | - | Human | 15245 | ||
| PTK2B (PYK2) | FAK | TK | 3fzr | A | n-methyl-n-{2-[({2-[(2-oxo-2,3-dihydro-1h-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]phenyl}methanesulfonamide | Human | 87 | |||
| PTK2B (PYK2) | FAK | TK | 3cc6 | A | A | - | Human | 93 | ||
| PTK2B (PYK2) | FAK | TK | 3cc6 | A | B | - | Human | 92 | ||
| PTK2B (PYK2) | FAK | TK | 3fzs | A | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 94 | |||
| PTK2B (PYK2) | FAK | TK | 3et7 | A | 5-{[4-{[2-(pyrrolidin-1-ylsulfonyl)benzyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,3-dihydro-2h-indol-2-one | Human | 90 | |||
| PTK2B (PYK2) | FAK | TK | 3fzp | A | phosphothiophosphoric acid-adenylate ester | Human | 88 | |||
| PTK2B (PYK2) | FAK | TK | 3fzt | A | 1-[5-tert-butyl-2-(4-methylphenyl)-1,2-dihydro-3h-pyrazol-3-ylidene]-3-{3-[(pyridin-3-yloxy)methyl]-1h-pyrazol-5-yl}urea | Human | 86 | |||
| PTK2B (PYK2) | FAK | TK | 4h1m | A | 7-({[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]carbamoyl}amino)-n-(propan-2-yl)-1h-indole-2-carboxamide | Human | 89 | |||
| PTK2B (PYK2) | FAK | TK | 8xox | A | A | n-methyl-n-{3-[({2-[(2-oxo-2,3-dihydro-1h-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamide | Human | 15171 | ||
| PTK2B (PYK2) | FAK | TK | 5to8 | A | 25-(methylsulfonyl)-8-(trifluoromethyl)-5,17,18,21,22,23,24,25-octahydro-12h-7,11-(azeno)-16,13-(metheno)pyrido[3,2-i]pyrrolo[1,2-q][1,3,7,11,17]pentaazacyclohenicosin-20(6h)-one | Human | 7316 | |||
| PTK2B (PYK2) | FAK | TK | 3fzo | A | - | Human | 95 | |||
| PTK2B (PYK2) | FAK | TK | 5tob | A | n-methyl-n-{3-[({2-[(2-oxo-2,3-dihydro-1h-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamide | Human | 8686 | |||
| PTK2B (PYK2) | FAK | TK | 4h1j | A | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-[3-(4-methoxy-2-methylphenyl)-1h-pyrazol-5-yl]urea | Human | 91 | |||
| PTK2B (PYK2) | FAK | TK | 8xox | A | B | n-methyl-n-{3-[({2-[(2-oxo-2,3-dihydro-1h-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamide | Human | 15172 |