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Search results (49 entries covering 32 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetails File
PIK3C3PIKAtypical4oysA(8s)-9-[(5-chloranylpyridin-3-yl)methyl]-2-[(3r)-3-methylmorpholin-4-yl]-8-(trifluoromethyl)-6,7,8,9a-tetrahydro-3h-pyrimido[1,2-a]pyrimidin-4-oneHuman9327
PIK3C3PIKAtypical7rsjABn-{4-[(7r,8r)-4-oxo-7-(propan-2-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl]pyridin-2-yl}cyclopropanecarboxamideHuman13982
PIK3C3PIKAtypical3ls8AA-Human9340
PIK3C3PIKAtypical6i3uA2-morpholin-4-yl-6-[7-[(2~{r})-1-morpholin-4-ylpropan-2-yl]oxy-9~{h}-thioxanthen-4-yl]pyran-4-oneHuman11292
PIK3C3PIKAtypical7rsvAA(5as,8ar,9s)-2-[(3r)-3-methylmorpholin-4-yl]-5,5a,6,7,8,8a-hexahydro-4h-cyclopenta[e]pyrazolo[1,5-a]pyrazin-4-oneHuman13985
PIK3C3PIKAtypical3ihyA-Human9341
PIK3C3PIKAtypical3ihyC-Human9331
PIK3C3PIKAtypical5anlA(8s)-2-(morpholin-4-yl)-9-[2-(propan-2-yloxy)ethyl]-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4h-pyrimido[1,2-a]pyrimidin-4-oneHuman9349
PIK3C3PIKAtypical3ls8AB-Human9348
PIK3C3PIKAtypical3ihyD-Human9337
PIK3C3PIKAtypical4ph4BB-Human9330
PIK3C3PIKAtypical7rspAB(7r,8r)-2-[(3r)-3-methylmorpholin-4-yl]-7-(propan-2-yl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-oneHuman13986
PIK3C3PIKAtypical7rspAA(7r,8r)-2-[(3r)-3-methylmorpholin-4-yl]-7-(propan-2-yl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-oneHuman13981
PIK3C3PIKAtypical5ennBA1-[[4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-yl]amino]-2-methyl-propan-2-olHuman9345
PIK3C3PIKAtypical13bvA-Human15507
PIK3C3PIKAtypical4uwkAB-Human9335
PIK3C3PIKAtypical9mhgB-Human15508
PIK3C3PIKAtypical7bl1B-Human13361
PIK3C3PIKAtypical9rx6A-Human15509
PIK3C3PIKAtypical9tw3A-Human15510
PIK3C3PIKAtypical4uwkAA-Human9342
PIK3C3PIKAtypical9mhhB-Human15511
PIK3C3PIKAtypical4uwhAA-Human9346
PIK3C3PIKAtypical9rx8A-Human15512
PIK3C3PIKAtypical4uwgAA-Human9347
PIK3C3PIKAtypical4uwfA-Human9328
PIK3C3PIKAtypical9s47A-Human15513
PIK3C3PIKAtypical5ennAA1-[[4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-yl]amino]-2-methyl-propan-2-olHuman9343
PIK3C3PIKAtypical9tz3Aadenosine-5'-diphosphateHuman15514
PIK3C3PIKAtypical5ennBB1-[[4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-yl]amino]-2-methyl-propan-2-olHuman9329
PIK3C3PIKAtypical3ls8BB-Human9339
PIK3C3PIKAtypical4uwlA-Human9332
PIK3C3PIKAtypical9rx7A-Human15517
PIK3C3PIKAtypical3ls8BA-Human9333
PIK3C3PIKAtypical9rxbA-Human15519
PIK3C3PIKAtypical4uwhAB-Human9334
PIK3C3PIKAtypical9rxaA-Human15518
PIK3C3PIKAtypical4ph4BA-Human9326
PIK3C3PIKAtypical9rx9A-Human15520
PIK3C3PIKAtypical9rx5A-Human15521
PIK3C3PIKAtypical5ennAB1-[[4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-yl]amino]-2-methyl-propan-2-olHuman9338
PIK3C3PIKAtypical3ihyB-Human9336
PIK3C3PIKAtypical3ihyE-Human9344
PIK3C3PIKAtypical6ykgA4-morpholin-4-yl-6-[(2~{r})-2-(phenylmethyl)pyrrolidin-1-yl]-1~{h}-pyridin-2-oneHuman13509
PIK3C3PIKAtypical4uwgAB-Human9350
PIK3C3PIKAtypical7rsjAAn-{4-[(7r,8r)-4-oxo-7-(propan-2-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl]pyridin-2-yl}cyclopropanecarboxamideHuman13983
PIK3C3PIKAtypical9tw2A-Human15515
PIK3C3PIKAtypical9rx4A-Human15516
PIK3C3PIKAtypical7rsvAB(5as,8ar,9s)-2-[(3r)-3-methylmorpholin-4-yl]-5,5a,6,7,8,8a-hexahydro-4h-cyclopenta[e]pyrazolo[1,5-a]pyrazin-4-oneHuman13984
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