Search results (15 entries covering 11 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
| RPS6KA3-b (RSK2-b) | RSKb | CAMK | 4d9u | A | tert-butyl (2s)-3-[4-amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl]-2-cyanopropanoate | Human | 1499 | |||
| RPS6KA3-b (RSK2-b) | RSKb | CAMK | 4jg8 | A | B | (2s)-2-cyano-n-(1-hydroxy-2-methylpropan-2-yl)-3-[3-(3,4,5-trimethoxyphenyl)-1h-indazol-5-yl]propanamide | Human | 1498 | ||
| RPS6KA3-b (RSK2-b) | RSKb | CAMK | 4jg8 | A | A | (2s)-2-cyano-n-(1-hydroxy-2-methylpropan-2-yl)-3-[3-(3,4,5-trimethoxyphenyl)-1h-indazol-5-yl]propanamide | Human | 1497 | ||
| RPS6KA3-b (RSK2-b) | RSKb | CAMK | 4jg7 | A | A | (2r)-2-cyano-3-[3-(1h-pyrrolo[2,3-b]pyridin-3-ylcarbonyl)phenyl]propanamide | Human | 1496 | ||
| RPS6KA3-b (RSK2-b) | RSKb | CAMK | 4jg7 | A | B | (2r)-2-cyano-3-[3-(1h-pyrrolo[2,3-b]pyridin-3-ylcarbonyl)phenyl]propanamide | Human | 1494 | ||
| RPS6KA3-b (RSK2-b) | RSKb | CAMK | 4jg6 | A | (2s)-2-cyano-3-(1h-indazol-5-yl)propanamide | Human | 1495 | |||
| RPS6KA3-b (RSK2-b) | RSKb | CAMK | 4d9t | A | methyl (2s)-3-{4-amino-7-[(1e)-3-hydroxyprop-1-en-1-yl]-5-(4-methylphenyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl}-2-cyanopropanoate | Human | 1493 | |||
| RPS6KA3-b (RSK2-b) | RSKb | CAMK | 8xey | A | - | Human | 15207 | |||
| Rps6ka3-b (RSK2-b) | RSKb | CAMK | 2qr7 | A | B | - | Mouse | 5757 | ||
| Rps6ka3-b (RSK2-b) | RSKb | CAMK | 2qr8 | A | B | - | Mouse | 5755 | ||
| Rps6ka3-b (RSK2-b) | RSKb | CAMK | 2qr7 | A | A | - | Mouse | 5759 | ||
| Rps6ka3-b (RSK2-b) | RSKb | CAMK | 4m8t | A | (2e)-2-cyano-3-[3-(1h-pyrazol-4-yl)phenyl]prop-2-enamide | Mouse | 5756 | |||
| Rps6ka3-b (RSK2-b) | RSKb | CAMK | 5o1s | A | dimethyl fumarate | Mouse | 9976 | |||
| Rps6ka3-b (RSK2-b) | RSKb | CAMK | 4mao | A | (2z)-2-(1h-1,2,4-triazol-1-yl)-3-[3-(3,4,5-trimethoxyphenyl)-1h-indazol-5-yl]prop-2-enenitrile | Mouse | 5758 | |||
| Rps6ka3-b (RSK2-b) | RSKb | CAMK | 2qr8 | A | A | - | Mouse | 5760 |