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Search results (102 entries covering 29 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetails File
Src (SRC)SrcTK6f3fAadenosine-5'-diphosphateMouse9461
SRCSrcTK6e6eEAn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11479
SRCSrcTK6e6eGAn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11493
SRCSrcTK2bdfB{[(4-{[2-(4-aminocyclohexyl)-9-ethyl-9h-purin-6-yl]amino}phenyl)(hydroxy)phosphoryl]methyl}phosphonic acidHuman975
SRCSrcTK7ng7Atert-butyl (4-(4-amino-1-(2-(4-(dimethylamino)piperidin-1-yl)ethyl)-1h-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenyl)carbamateHuman13900
SRCSrcTK9ns1A17-Human15594
SRCSrcTK9ns0A15-Human15598
SRCSrcTK9ns1A12-Human15595
SRCSrcTK9ns1A1-Human15599
SRCSrcTK9ns1A10-Human15600
SRCSrcTK9ns0A2-Human15601
SRCSrcTK9ns1A13-Human15602
SRCSrcTK9ns1A11-Human15596
SRCSrcTK9ns0A20-Human15597
SRCSrcTK9ns0A1-Human15603
SRCSrcTK9ns1A15-Human15604
SRCSrcTK9ns1A6-Human15605
SRCSrcTK9ns0A8-Human15606
SRCSrcTK9ns1A2-Human15607
SRCSrcTK9ns0A3-Human15608
SRCSrcTK9ns0A18-Human15609
SRCSrcTK9ns0A5-Human15610
SRCSrcTK9ns0A13-Human15611
SRCSrcTK9ns0A16-Human15624
SRCSrcTK4mxoB4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrileHuman978
SRCSrcTK6ateAn-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propanamideHuman10920
SRCSrcTK2bdfA{[(4-{[2-(4-aminocyclohexyl)-9-ethyl-9h-purin-6-yl]amino}phenyl)(hydroxy)phosphoryl]methyl}phosphonic acidHuman980
SRCSrcTK6e6eECn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11478
SRCSrcTK6e6eHAn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11475
SRCSrcTK8jf3A2-[4-[4-[bis(oxidanylidene)-$l^5-sulfanyl]oxyphenyl]carbonylpiperazin-1-yl]-6-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]-n-prop-2-ynyl-pyrimidine-4-carboxamideHuman15226
SRCSrcTK9ns0A6-Human15613
SRCSrcTK1yomA2-({6-[(3-chlorophenyl)amino]-9-isopropyl-9h-purin-2-yl}amino)-3-methylbutan-1-olHuman973
SRCSrcTK9irlA(2~{r})-2-[3,5-bis(fluoranyl)phenyl]-2-[2-chloranylethanoyl(cyclopropyl)amino]-~{n}-cyclopentyl-ethanamideHuman15614
SRCSrcTK6e6eEBn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11490
SRCSrcTK9ns0A14-Human15622
SRCSrcTK9ns1A16-Human15623
SRCSrcTK8jn9An-[(1r)-1-[3,5-bis(fluoranyl)phenyl]-2-(cyclopentylamino)-2-oxidanylidene-ethyl]-n-cyclopropyl-prop-2-enamideHuman15313
SRCSrcTK9ns0A9-Human15625
Src (SRC)SrcTK8xn8AAadenosine-5'-diphosphateMouse15182
Src (SRC)SrcTK8xn8ABadenosine-5'-diphosphateMouse15183
SRCSrcTK1yi6B-Human991
SRCSrcTK6e6eDBn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11494
SRCSrcTK8haqA4-[(~{e})-(7-oxidanyl-6~{h}-pyrrolo[2,3-g][1,3]benzothiazol-8-yl)methylideneamino]-~{n}-pyridin-2-yl-benzenesulfonamideHuman14883
SRCSrcTK1fmkA-Human981
SRCSrcTK4mxyA4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrileHuman982
SRCSrcTK6e6eFAn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11487
SRCSrcTK1yolB1-{4-[4-amino-5-(3-methoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-7-yl]benzyl}piperidin-4-olHuman966
SRCSrcTK6e6eAAn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11485
SRCSrcTK6e6eHCn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11481
SRCSrcTK6e6eCCn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11488
SRCSrcTK1y57A4-[(4-methylpiperazin-1-yl)methyl]-n-{3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}benzamideHuman986
SRCSrcTK6e6eGCn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11477
SRCSrcTK1yojB-Human974
SRCSrcTK6e6eFBn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11472
SRCSrcTK8jn8A(2r)-n-cyclopentyl-2-[cyclopropyl(ethanoyl)amino]-2-(4-fluorophenyl)ethanamideHuman15312
SRCSrcTK4k11AA1-tert-butyl-3-(naphthalen-1-yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amineHuman983
SRCSrcTK6e6eDAn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11489
SRCSrcTK6e6eBAn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11480
SRCSrcTK4mxyB4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrileHuman972
SRCSrcTK4mxzA4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrileHuman969
SRCSrcTK6e6eBCn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11484
SRCSrcTK9ns0A7-Human15612
SRCSrcTK2bdjA3-[2-(2-cyclopentyl-6-{[4-(dimethylphosphoryl)phenyl]amino}-9h-purin-9-yl)ethyl]phenolHuman971
SRCSrcTK4mxzB4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrileHuman988
SRCSrcTK9ns1A8-Human15615
SRCSrcTK2h8hAAn-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(tetrahydro-2h-pyran-4-yloxy)quinazolin-4-amineHuman970
SRCSrcTK9ns1A14-Human15616
SRCSrcTK6e6eCBn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11492
SRCSrcTK9ns0A10-Human15617
SRCSrcTK6e6eHBn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11483
SRCSrcTK9ns1A4-Human15618
SRCSrcTK4mxxB4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrileHuman976
SRCSrcTK4mxoA4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrileHuman990
SRCSrcTK6e6eCAn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11471
SRCSrcTK6e6eDCn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11473
SRCSrcTK1yolA1-{4-[4-amino-5-(3-methoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-7-yl]benzyl}piperidin-4-olHuman968
SRCSrcTK6e6eFCn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11486
SRCSrcTK9ns0A11-Human15619
SRCSrcTK9ns1A5-Human15620
SRCSrcTK6e6eGBn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11474
SRCSrcTK2h8hABn-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(tetrahydro-2h-pyran-4-yloxy)quinazolin-4-amineHuman992
SRCSrcTK9ns0A19-Human15621
SRCSrcTK6e6eACn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11491
SRCSrcTK6e6eABn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11482
SRCSrcTK1yi6A-Human967
SRCSrcTK9ns0A17-Human15626
SRCSrcTK9ns1A3-Human15627
SRCSrcTK9ns1A19-Human15628
SRCSrcTK6e6eBBn-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamideHuman11476
SRCSrcTK1yojA-Human984
SRCSrcTK1kswAn6-benzyl adenosine-5'-diphosphateHuman985
SRCSrcTK9ns1A7-Human15629
SRCSrcTK9ns1A9-Human15630
SRCSrcTK7oteA3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamideHuman14240
SRCSrcTK4k11AB1-tert-butyl-3-(naphthalen-1-yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amineHuman977
SRCSrcTK9ns1A18-Human15631
SRCSrcTK4mxxA4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrileHuman989
SRCSrcTK1yomB2-({6-[(3-chlorophenyl)amino]-9-isopropyl-9h-purin-2-yl}amino)-3-methylbutan-1-olHuman987
SRCSrcTK9ns1A20-Human15632
SRCSrcTK9ns0A12-Human15633
SRCSrcTK2srcAphosphoaminophosphonic acid-adenylate esterHuman979
SRCSrcTK9ns0A4-Human15634
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