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Search results (101 entries covering 61 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetails File
MAPK10 (JNK3)MAPKCMGC4x21An-ethyl-4-{[4-(1h-indol-3-yl)-5-iodopyrimidin-2-yl]amino}piperidine-1-carboxamideHuman6240
MAPK10 (JNK3)MAPKCMGC4h36AB-Human3461
MAPK10 (JNK3)MAPKCMGC3oxiAmethyl 3-[(thiophen-2-ylacetyl)amino]thiophene-2-carboxylateHuman3423
MAPK10 (JNK3)MAPKCMGC6emhCB4-(4-methyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amineHuman10505
MAPK10 (JNK3)MAPKCMGC2p33A4-{[5-chloro-4-(1h-indol-3-yl)pyrimidin-2-yl]amino}-n-ethylpiperidine-1-carboxamideHuman3455
MAPK10 (JNK3)MAPKCMGC7kskA4-(4-{[(2-chlorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-n-(oxetan-3-yl)thiophene-2-carboxamideHuman13386
MAPK10 (JNK3)MAPKCMGC2zduA4-[(4-{[6-bromo-3-(methoxycarbonyl)-1-oxo-4-phenylisoquinolin-2(1h)-yl]methyl}phenyl)amino]-4-oxobutanoic acidHuman3479
MAPK10 (JNK3)MAPKCMGC7yl1A7-hexyl-3-methyl-8-sulfanylidene-9h-purine-2,6-dioneHuman14845
MAPK10 (JNK3)MAPKCMGC3v6rAA4-{[4-(dimethylamino)butanoyl]amino}-n-(3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamideHuman3441
MAPK10 (JNK3)MAPKCMGC8wgfABphosphoaminophosphonic acid-adenylate esterHuman15047
MAPK10 (JNK3)MAPKCMGC2o0uAn-{3-cyano-6-[3-(1-piperidinyl)propanoyl]-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl}1-naphthalenecarboxamideHuman3415
MAPK10 (JNK3)MAPKCMGC3fi3AA3-{5-[(2-fluorophenyl)amino]-1h-indazol-1-yl}-n-(3,4,5-trimethoxyphenyl)benzamideHuman3442
MAPK10 (JNK3)MAPKCMGC3fi3AB3-{5-[(2-fluorophenyl)amino]-1h-indazol-1-yl}-n-(3,4,5-trimethoxyphenyl)benzamideHuman3445
MAPK10 (JNK3)MAPKCMGC3fi2AA3-{4-[(phenylcarbamoyl)amino]-1h-pyrazol-1-yl}-n-(3,4,5-trimethoxyphenyl)benzamideHuman3463
MAPK10 (JNK3)MAPKCMGC4h3bAC-Human3453
MAPK10 (JNK3)MAPKCMGC3fv8AA5-bromo-n-(3-chloro-2-(4-(prop-2-ynyl)piperazin-1-yl)phenyl)furan-2-carboxamideHuman3468
MAPK10 (JNK3)MAPKCMGC6emhCA4-(4-methyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amineHuman10507
MAPK10 (JNK3)MAPKCMGC3kvxABn-[(2z)-4-(3-fluoro-5-morpholin-4-ylphenyl)pyrimidin-2(1h)-ylidene]-4-(3-morpholin-4-yl-1h-1,2,4-triazol-1-yl)anilineHuman3430
MAPK10 (JNK3)MAPKCMGC6ekdAB4-(4-methyl-2-methylsulfanyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amineHuman10502
MAPK10 (JNK3)MAPKCMGC7orfAAn-[4-[[4-[5-(4-fluorophenyl)-3-methyl-2-methylsulfanyl-imidazol-4-yl]pyridin-2-yl]amino]phenyl]-3-(propanoylamino)benzamideHuman13812
MAPK10 (JNK3)MAPKCMGC6emhAA4-(4-methyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amineHuman10508
MAPK10 (JNK3)MAPKCMGC6eq9AAphosphomethylphosphonic acid adenylate esterHuman10500
MAPK10 (JNK3)MAPKCMGC3g9nA(3z)-1-[(6-fluoro-4h-1,3-benzodioxin-8-yl)methyl]-4-phenyl-1h-indole-2,3-dione 3-oximeHuman3416
MAPK10 (JNK3)MAPKCMGC1pmnAcyclopropyl-{4-[5-(3,4-dichlorophenyl)-2-[(1-methyl)-piperidin]-4-yl-3-propyl-3h-imidazol-4-yl]-pyrimidin-2-yl}amineHuman3439
MAPK10 (JNK3)MAPKCMGC2ok1AAn-benzyl-4-[4-(3-chlorophenyl)-1h-pyrazol-3-yl]-1h-pyrrole-2-carboxamideHuman3444
MAPK10 (JNK3)MAPKCMGC4h36AA-Human3459
MAPK10 (JNK3)MAPKCMGC3v6rBA4-{[4-(dimethylamino)butanoyl]amino}-n-(3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamideHuman3427
MAPK10 (JNK3)MAPKCMGC2o2uAn-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-fluorobenzamideHuman3457
MAPK10 (JNK3)MAPKCMGC7s1nAB4-[5-(2-chloro-6-fluoroanilino)-6-methyl-1h-pyrazolo[3,4-b]pyridin-1-yl]-n-(oxetan-3-yl)thiophene-2-carboxamideHuman13957
MAPK10 (JNK3)MAPKCMGC3g90X(3e)-5-fluoro-1-[(6-fluoro-4h-1,3-benzodioxin-8-yl)methyl]-1h-indole-2,3-dione 3-oximeHuman3477
MAPK10 (JNK3)MAPKCMGC6eq9ABphosphomethylphosphonic acid adenylate esterHuman10509
MAPK10 (JNK3)MAPKCMGC3fv8AB5-bromo-n-(3-chloro-2-(4-(prop-2-ynyl)piperazin-1-yl)phenyl)furan-2-carboxamideHuman3426
MAPK10 (JNK3)MAPKCMGC4kkeAadenosine monophosphateHuman3448
MAPK10 (JNK3)MAPKCMGC3da6An-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)naphthalen-1-yl]-1h-benzimidazol-2-amineHuman3476
MAPK10 (JNK3)MAPKCMGC2r9sAn-(tert-butyl)-4-[5-(pyridin-2-ylamino)quinolin-3-yl]benzenesulfonamideHuman3450
MAPK10 (JNK3)MAPKCMGC4h39AA-Human3460
MAPK10 (JNK3)MAPKCMGC4kkgA-Human3443
MAPK10 (JNK3)MAPKCMGC3cgoA2-{4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]piperidin-1-yl}-n-methylacetamideHuman6771
MAPK10 (JNK3)MAPKCMGC3oy1A5-[2-(cyclohexylamino)pyridin-4-yl]-4-naphthalen-2-yl-2-(tetrahydro-2h-pyran-4-yl)-2,4-dihydro-3h-1,2,4-triazol-3-oneHuman3469
MAPK10 (JNK3)MAPKCMGC7oreAB4-(dimethylamino)-n-[(5z)-9-[[4-[5-(4-fluorophenyl)-3-methyl-2-methylsulfanyl-imidazol-4-yl]pyridin-2-yl]amino]-11,12-dihydrobenzo[c][1,2]benzodiazocin-2-yl]butanamideHuman13810
MAPK10 (JNK3)MAPKCMGC4y46A1-{trans-4-[(8-cyclopentyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]cyclohexyl}-3-propan-2-ylureaHuman3414
MAPK10 (JNK3)MAPKCMGC7oreAA4-(dimethylamino)-n-[(5z)-9-[[4-[5-(4-fluorophenyl)-3-methyl-2-methylsulfanyl-imidazol-4-yl]pyridin-2-yl]amino]-11,12-dihydrobenzo[c][1,2]benzodiazocin-2-yl]butanamideHuman13811
MAPK10 (JNK3)MAPKCMGC2b1pA3-{6-[(2-chlorophenyl)amino]-1h-indazol-3-yl}-5-{[4-(dimethylamino)butanoyl]amino}benzoic acidHuman3464
MAPK10 (JNK3)MAPKCMGC1pmuA9-(4-hydroxyphenyl)-2,7-phenanthrolineHuman3474
MAPK10 (JNK3)MAPKCMGC4h3bAA-Human3480
MAPK10 (JNK3)MAPKCMGC4z9lAAphosphoaminophosphonic acid-adenylate esterHuman3432
MAPK10 (JNK3)MAPKCMGC6emhDB4-(4-methyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amineHuman10496
MAPK10 (JNK3)MAPKCMGC6eq9BAphosphomethylphosphonic acid adenylate esterHuman10504
MAPK10 (JNK3)MAPKCMGC3cgfAn-cyclohexyl-4-imidazo[1,2-a]pyridin-3-yl-n-methylpyrimidin-2-amineHuman6770
MAPK10 (JNK3)MAPKCMGC4y5hA1-(trans-4-{[7-oxo-8-(propan-2-yl)-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}cyclohexyl)-3-propan-2-ylureaHuman3431
MAPK10 (JNK3)MAPKCMGC4whzAA3-(4-{[(2-chlorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-n-{1-[(3s)-pyrrolidin-3-yl]-1h-pyrazol-4-yl}benzamideHuman3429
MAPK10 (JNK3)MAPKCMGC4w4wAn-(2-methylpyridin-4-yl)-3-{4-[(phenylcarbamoyl)amino]-1h-pyrazol-1-yl}benzamideHuman3418
MAPK10 (JNK3)MAPKCMGC3v6rAB4-{[4-(dimethylamino)butanoyl]amino}-n-(3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamideHuman3436
MAPK10 (JNK3)MAPKCMGC2excXn-{2'-[(4-fluorophenyl)amino]-4,4'-bipyridin-2-yl}-4-methoxycyclohexanecarboxamideHuman3478
MAPK10 (JNK3)MAPKCMGC3rtpAn-[4-cyano-3-(1h-1,2,4-triazol-5-yl)thiophen-2-yl]-2-(2-oxo-3,4-dihydroquinolin-1(2h)-yl)acetamideHuman3467
MAPK10 (JNK3)MAPKCMGC2wajAA1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinolineHuman3472
MAPK10 (JNK3)MAPKCMGC4w4vA3-(4-{[(2-chlorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-n-(2-methylpyridin-4-yl)benzamideHuman3437
MAPK10 (JNK3)MAPKCMGC3ttjAA9-cyclopentyl-n~8~-(2-fluorophenyl)-n~2~-(4-methoxyphenyl)-9h-purine-2,8-diamineHuman3458
MAPK10 (JNK3)MAPKCMGC3v6rBB4-{[4-(dimethylamino)butanoyl]amino}-n-(3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamideHuman3417
MAPK10 (JNK3)MAPKCMGC4x21Bn-ethyl-4-{[4-(1h-indol-3-yl)-5-iodopyrimidin-2-yl]amino}piperidine-1-carboxamideHuman6239
MAPK10 (JNK3)MAPKCMGC8wgfAAphosphoaminophosphonic acid-adenylate esterHuman15046
MAPK10 (JNK3)MAPKCMGC4z9lABphosphoaminophosphonic acid-adenylate esterHuman3438
MAPK10 (JNK3)MAPKCMGC6eq9BBphosphomethylphosphonic acid adenylate esterHuman10499
MAPK10 (JNK3)MAPKCMGC3ttjAB9-cyclopentyl-n~8~-(2-fluorophenyl)-n~2~-(4-methoxyphenyl)-9h-purine-2,8-diamineHuman3428
MAPK10 (JNK3)MAPKCMGC2r9sBn-(tert-butyl)-4-[5-(pyridin-2-ylamino)quinolin-3-yl]benzenesulfonamideHuman3420
MAPK10 (JNK3)MAPKCMGC7ksiA4-(4-{[(2-chloro-6-fluorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-5-methyl-n-(oxetan-3-yl)thiophene-2-carboxamideHuman13387
MAPK10 (JNK3)MAPKCMGC1pmvA2,6-dihydroanthra/1,9-cd/pyrazol-6-oneHuman3434
MAPK10 (JNK3)MAPKCMGC4h3bCC-Human3446
MAPK10 (JNK3)MAPKCMGC1jnkAphosphoaminophosphonic acid-adenylate esterHuman3451
MAPK10 (JNK3)MAPKCMGC4w4xA3-(4-{[(4-fluorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-n-(2-methylpyridin-4-yl)benzamideHuman3440
MAPK10 (JNK3)MAPKCMGC4h3bAB-Human3454
MAPK10 (JNK3)MAPKCMGC8bzpAB2-bromanyl-2,2-bis(fluoranyl)-~{n}-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ethanamideHuman14858
MAPK10 (JNK3)MAPKCMGC7s1nAA4-[5-(2-chloro-6-fluoroanilino)-6-methyl-1h-pyrazolo[3,4-b]pyridin-1-yl]-n-(oxetan-3-yl)thiophene-2-carboxamideHuman13958
MAPK10 (JNK3)MAPKCMGC3ttiAtrans-4-({9-[(3s)-tetrahydrofuran-3-yl]-8-[(2,4,6-trifluorophenyl)amino]-9h-purin-2-yl}amino)cyclohexanolHuman3456
MAPK10 (JNK3)MAPKCMGC4whzAB3-(4-{[(2-chlorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-n-{1-[(3s)-pyrrolidin-3-yl]-1h-pyrazol-4-yl}benzamideHuman3422
MAPK10 (JNK3)MAPKCMGC6emhBA4-(4-methyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amineHuman10506
MAPK10 (JNK3)MAPKCMGC3g9lX(3z)-1-[(6-fluoro-4h-1,3-benzodioxin-8-yl)methyl]-4-[(e)-2-phenylethenyl]-1h-indole-2,3-dione 3-oximeHuman3435
MAPK10 (JNK3)MAPKCMGC4h39AB-Human3462
MAPK10 (JNK3)MAPKCMGC3v6sAB3-{[4-(dimethylamino)butanoyl]amino}-n-(4-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamideHuman3449
MAPK10 (JNK3)MAPKCMGC3fi2AB3-{4-[(phenylcarbamoyl)amino]-1h-pyrazol-1-yl}-n-(3,4,5-trimethoxyphenyl)benzamideHuman3452
MAPK10 (JNK3)MAPKCMGC6emhDA4-(4-methyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amineHuman10497
MAPK10 (JNK3)MAPKCMGC7oreAC4-(dimethylamino)-n-[(5z)-9-[[4-[5-(4-fluorophenyl)-3-methyl-2-methylsulfanyl-imidazol-4-yl]pyridin-2-yl]amino]-11,12-dihydrobenzo[c][1,2]benzodiazocin-2-yl]butanamideHuman13813
MAPK10 (JNK3)MAPKCMGC4kkhAcyclopropyl[(3r)-3-({4-[6-hydroxy-2-(naphthalen-2-yl)-1h-benzimidazol-1-yl]pyrimidin-2-yl}amino)piperidin-1-yl]methanoneHuman3419
MAPK10 (JNK3)MAPKCMGC3ptgAn-[4-methyl-3-(1h-1,2,4-triazol-5-yl)thiophen-2-yl]-2-(2-oxo-3,4-dihydroquinolin-1(2h)-yl)acetamideHuman3470
MAPK10 (JNK3)MAPKCMGC7ksjA4-(4-{[(2-chloro-6-fluorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-n-(oxetan-3-yl)thiophene-2-carboxamideHuman13388
MAPK10 (JNK3)MAPKCMGC2wajAB1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinolineHuman3471
MAPK10 (JNK3)MAPKCMGC2ok1ABn-benzyl-4-[4-(3-chlorophenyl)-1h-pyrazol-3-yl]-1h-pyrrole-2-carboxamideHuman3473
MAPK10 (JNK3)MAPKCMGC6emhAB4-(4-methyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amineHuman10503
MAPK10 (JNK3)MAPKCMGC2zdtAB4-[(6-chloro-1-oxo-4-phenyl-3-propanoylisoquinolin-2(1h)-yl)methyl]benzoic acidHuman3424
MAPK10 (JNK3)MAPKCMGC7orfABn-[4-[[4-[5-(4-fluorophenyl)-3-methyl-2-methylsulfanyl-imidazol-4-yl]pyridin-2-yl]amino]phenyl]-3-(propanoylamino)benzamideHuman13814
MAPK10 (JNK3)MAPKCMGC4u79An-{4-[(3-{2-[(trans-4-aminocyclohexyl)amino]pyrimidin-4-yl}pyridin-2-yl)oxy]naphthalen-1-yl}benzenesulfonamideHuman3466
MAPK10 (JNK3)MAPKCMGC3v6sBB3-{[4-(dimethylamino)butanoyl]amino}-n-(4-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamideHuman3425
MAPK10 (JNK3)MAPKCMGC3kvxAAn-[(2z)-4-(3-fluoro-5-morpholin-4-ylphenyl)pyrimidin-2(1h)-ylidene]-4-(3-morpholin-4-yl-1h-1,2,4-triazol-1-yl)anilineHuman3433
MAPK10 (JNK3)MAPKCMGC8enjAn-[3-({(4p)-4-[(3m)-1-tert-butyl-3-(3-hydroxyphenyl)-1h-pyrazol-4-yl]pyridin-2-yl}amino)propyl]-4-hydroxybenzene-1-sulfonamideHuman14884
MAPK10 (JNK3)MAPKCMGC2zdtAA4-[(6-chloro-1-oxo-4-phenyl-3-propanoylisoquinolin-2(1h)-yl)methyl]benzoic acidHuman3421
MAPK10 (JNK3)MAPKCMGC4h3bCB-Human3465
MAPK10 (JNK3)MAPKCMGC8bzpAA2-bromanyl-2,2-bis(fluoranyl)-~{n}-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ethanamideHuman14859
MAPK10 (JNK3)MAPKCMGC4w4yA3-(4-{[(4-methylphenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-n-(2-methylpyridin-4-yl)benzamideHuman3447
MAPK10 (JNK3)MAPKCMGC6ekdAA4-(4-methyl-2-methylsulfanyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amineHuman10498
MAPK10 (JNK3)MAPKCMGC6emhBB4-(4-methyl-1~{h}-imidazol-5-yl)-~{n}-(4-morpholin-4-ylphenyl)pyridin-2-amineHuman10501
MAPK10 (JNK3)MAPKCMGC4h3bCA-Human3475
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