| MET | Met | TK | 8k78 | A | B | - | Human | 15351 | |
| MET | Met | TK | 8k78 | A | A | - | Human | 15352 | |
| MET | Met | TK | 7v3r | A | B | ~{n}1'-[3-fluoranyl-4-(2-phenylazanylpyrimidin-4-yl)oxy-phenyl]-~{n}1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 14330 | |
| MET | Met | TK | 7v3s | A | A | ~{n}1'-[3-fluoranyl-4-(10~{h}-pyrido[3,2-b][1,4]benzoxazin-4-yloxy)phenyl]-~{n}1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 14329 | |
| MET | Met | TK | 7v3s | A | B | ~{n}1'-[3-fluoranyl-4-(10~{h}-pyrido[3,2-b][1,4]benzoxazin-4-yloxy)phenyl]-~{n}1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 14327 | |
| MET | Met | TK | 7v3r | A | A | ~{n}1'-[3-fluoranyl-4-(2-phenylazanylpyrimidin-4-yl)oxy-phenyl]-~{n}1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 14328 | |
| MET | Met | TK | 8gvj | A | | (1^4z,5^2e)-6^3-(trifluoromethyl)-5^1,5^6-dihydro-1^1h-8-aza-2(3,6)-quinolina-5(1,3)-pyridazina-1(4,1)-pyrazola-6(1,4)-benzenacyclododecaphane-5^6,7-dione | Human | 14549 | |
| MET | Met | TK | 7y4u | A | | ~{n}-methyl-4-[1-[2-[3-(1-methylpyrazol-4-yl)quinolin-6-yl]ethyl]-6-oxidanylidene-pyridazin-3-yl]-2-(trifluoromethyl)benzamide | Human | 14550 | |
| MET | Met | TK | 7y4t | A | | 2-[2-[3-(1-methylpyrazol-4-yl)quinolin-6-yl]ethyl]-6-(3-nitrophenyl)pyridazin-3-one | Human | 14548 | |
| MET | Met | TK | 8ouu | A | A | 5-(3-ethynyl-5-fluoranyl-1h-indazol-7-yl)-1-[(1s)-1-phenylethyl]pyrimidine-2,4-dione | Human | 14821 | |
| MET | Met | TK | 8ouu | A | B | 5-(3-ethynyl-5-fluoranyl-1h-indazol-7-yl)-1-[(1s)-1-phenylethyl]pyrimidine-2,4-dione | Human | 14824 | |
| MET | Met | TK | 7b3w | A | B | 3-(6-fluoranyl-1~{h}-indazol-4-yl)-4,5-dihydro-1~{h}-pyrrolo[3,4-b]pyrrol-6-one | Human | 13178 | |
| MET | Met | TK | 3dkf | A | A | 6-{[6-(1-methyl-1h-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline | Human | 3030 | |
| MET | Met | TK | 3qti | A | A | 6-{[6-(1-methyl-1h-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]methyl}quinoline | Human | 2994 | |
| MET | Met | TK | 6sdc | A | A | n-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 11532 | |
| MET | Met | TK | 3f66 | B | B | 3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol | Human | 2992 | |
| MET | Met | TK | 5eyc | A | A | 6-[(1~{r})-1-[8-fluoranyl-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one | Human | 6401 | |
| MET | Met | TK | 5dg5 | B | B | n-(2,5-difluoro-4-{[2-(1-methyl-1h-pyrazol-4-yl)pyridin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 7036 | |
| MET | Met | TK | 4knb | A | B | 7-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine | Human | 3037 | |
| MET | Met | TK | 3qti | B | B | 6-{[6-(1-methyl-1h-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]methyl}quinoline | Human | 3024 | |
| MET | Met | TK | 5hor | A | | 1-(6-{[6-(4-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1,3-benzothiazol-2-yl)-3-[2-(morpholin-4-yl)ethyl]urea | Human | 7276 | |
| MET | Met | TK | 5eyd | A | B | 6-[(1~{r})-1-[8-fluoranyl-6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(2-methoxyethoxy)-1,6-naphthyridin-5-one | Human | 6399 | |
| MET | Met | TK | 5uab | A | B | n-{6-[([1,2,4]triazolo[4,3-a]pyridin-3-yl)sulfanyl]imidazo[1,2-b]pyridazin-2-yl}cyclopropanecarboxamide | Human | 7964 | |
| MET | Met | TK | 3dkg | A | B | 6-{[6-(1-methyl-1h-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline | Human | 3019 | |
| MET | Met | TK | 4mxc | A | B | n-(3-fluoro-4-{[2-({3-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 3025 | |
| MET | Met | TK | 2wd1 | A | B | 1-[(2-nitrophenyl)sulfonyl]-1h-pyrrolo[3,2-b]pyridine-6-carboxamide | Human | 2976 | |
| MET | Met | TK | 8an8 | A | | 3-[bis(fluoranyl)methyl]-~{n}-methyl-~{n}-[(1~{r})-8-methyl-5-(3-methyl-1~{h}-indazol-6-yl)-1,2,3,4-tetrahydronaphthalen-1-yl]pyridine-2-carboxamide | Human | 14355 | |
| MET | Met | TK | 8ans | A | | 3-[bis(fluoranyl)methyl]-~{n}-methyl-~{n}-[(1~{r})-8-methyl-5-(3-methyl-1~{h}-indazol-6-yl)-1,2,3,4-tetrahydronaphthalen-1-yl]pyridine-2-carboxamide | Human | 14356 | |
| MET | Met | TK | 8aw1 | A | B | 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile | Human | 14980 | |
| MET | Met | TK | 8aw1 | A | A | 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile | Human | 14981 | |
| MET | Met | TK | 8au3 | A | | 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile | Human | 14982 | |
| MET | Met | TK | 8au5 | A | | 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile | Human | 14983 | |
| MET | Met | TK | 8ow3 | A | | 5-[3,5-bis(fluoranyl)phenyl]-1-[(1s)-1-phenylethyl]pyrimidine-2,4-dione | Human | 14818 | |
| MET | Met | TK | 8owg | A | | 5-[3,5-bis(fluoranyl)phenyl]-1-[(1s)-1-phenylethyl]pyrimidine-2,4-dione | Human | 14819 | |
| MET | Met | TK | 8ouv | A | A | 5-(1h-indazol-7-yl)-1-[(1s)-1-phenylethyl]pyrimidine-2,4-dione | Human | 14820 | |
| MET | Met | TK | 8ouv | A | B | 5-(1h-indazol-7-yl)-1-[(1s)-1-phenylethyl]pyrimidine-2,4-dione | Human | 14823 | |
| MET | Met | TK | 8ov7 | A | | 5-[3,5-bis(fluoranyl)phenyl]-1-[(1s)-1-[3-(1h-imidazol-5-yl)phenyl]ethyl]pyrimidine-2,4-dione | Human | 14817 | |
| MET | Met | TK | 8ovz | A | | 1-[(1s)-1-[3-(1h-imidazol-4-yl)phenyl]ethyl]-5-(1h-indazol-7-yl)pyrimidine-2,4-dione | Human | 14822 | |
| MET | Met | TK | 4knb | B | A | 7-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine | Human | 3007 | |
| MET | Met | TK | 6sde | A | | volitinib | Human | 11535 | |
| MET | Met | TK | 4xyf | A | A | 6-{(1s)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(2-methoxyethoxy)quinoline | Human | 2986 | |
| MET | Met | TK | 7b43 | A | | 3-[(4-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridine | Human | 13189 | |
| MET | Met | TK | 4r1v | A | A | 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile | Human | 3004 | |
| MET | Met | TK | 4deh | A | | 5-phenyl-3-(quinolin-6-ylmethyl)-3,5,6,7-tetrahydro-4h-[1,2,3]triazolo[4,5-c]pyridin-4-one | Human | 2963 | |
| MET | Met | TK | 7b42 | A | | 3-[(3-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridine | Human | 13190 | |
| MET | Met | TK | 4r1y | A | | 3-(diethylamino)propyl (3-{[5-(3,4-dimethoxyphenyl)-2-oxo-2h-1,3,4-thiadiazin-3(6h)-yl]methyl}phenyl)carbamate | Human | 2973 | |
| MET | Met | TK | 7b3t | A | B | 3-(phenylmethyl)-1~{h}-pyrrolo[2,3-b]pyridine | Human | 13191 | |
| MET | Met | TK | 7b3v | A | B | 3-(3-methyl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)-1~{h}-pyrrolo[3,4-b]pyrrol-6-one | Human | 13194 | |
| MET | Met | TK | 3u6h | A | B | n-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazole-4-carboxamide | Human | 2965 | |
| MET | Met | TK | 3a4p | A | | (2e)-3-{6-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]quinolin-3-yl}-n-methylprop-2-enamide | Human | 3005 | |
| MET | Met | TK | 4knb | B | B | 7-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine | Human | 2970 | |
| MET | Met | TK | 2wgj | A | | 3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1h-pyrazol-4-yl)pyridin-2-amine | Human | 3009 | |
| MET | Met | TK | 5hti | A | B | n-[3-fluoro-4-({7-[2-(morpholin-4-yl)ethoxy]-1,6-naphthyridin-4-yl}oxy)phenyl]-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 8009 | |
| MET | Met | TK | 3zc5 | A | | 6-{(1s)-1-[6-(1-methyl-1h-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]ethyl}quinoline | Human | 3003 | |
| MET | Met | TK | 4gg7 | A | A | n-(3-nitrobenzyl)-6-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]-2-(trifluoromethyl)pyrido[2,3-d]pyrimidin-4-amine | Human | 3002 | |
| MET | Met | TK | 3u6h | A | A | n-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazole-4-carboxamide | Human | 2996 | |
| MET | Met | TK | 5dg5 | A | A | n-(2,5-difluoro-4-{[2-(1-methyl-1h-pyrazol-4-yl)pyridin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 7037 | |
| MET | Met | TK | 3u6i | A | | n-{3-fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl}-1-[(2r)-2-hydroxypropyl]-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazole-4-carboxamide | Human | 2967 | |
| MET | Met | TK | 3cth | A | | n-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide | Human | 6768 | |
| MET | Met | TK | 3f66 | B | D | 3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol | Human | 3000 | |
| MET | Met | TK | 9c1r | A | A | n-(2,5-difluoro-4-{[(1s,3s)-3-(1-methyl-1h-pyrazol-3-yl)cyclobutyl][(8r)-pyrazolo[1,5-a]pyrazin-4-yl]amino}phenyl)-2-(5-fluoropyridin-2-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide | Human | 15368 | |
| MET | Met | TK | 3efj | B | | 2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-3-methylpyrimidin-4(3h)-one | Human | 2957 | |
| MET | Met | TK | 9c1r | A | B | n-(2,5-difluoro-4-{[(1s,3s)-3-(1-methyl-1h-pyrazol-3-yl)cyclobutyl][(8r)-pyrazolo[1,5-a]pyrazin-4-yl]amino}phenyl)-2-(5-fluoropyridin-2-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide | Human | 15369 | |
| MET | Met | TK | 3ctj | A | A | 2-(4-fluorophenyl)-n-{[3-fluoro-4-(1h-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide | Human | 6767 | |
| MET | Met | TK | 7b3q | A | A | 1-(phenylmethyl)-5~{h}-pyrrolo[3,2-c]pyridin-4-one | Human | 13177 | |
| MET | Met | TK | 3lq8 | A | A | n-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 2998 | |
| MET | Met | TK | 5dg5 | B | A | n-(2,5-difluoro-4-{[2-(1-methyl-1h-pyrazol-4-yl)pyridin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 7035 | |
| MET | Met | TK | 3lq8 | A | B | n-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 2964 | |
| MET | Met | TK | 3cd8 | A | B | 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline | Human | 2995 | |
| MET | Met | TK | 4eev | A | A | n-(3-fluoro-4-{[1-methyl-6-(1h-pyrazol-4-yl)-1h-indazol-5-yl]oxy}phenyl)-1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide | Human | 3012 | |
| MET | Met | TK | 3f66 | A | A | 3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol | Human | 2989 | |
| MET | Met | TK | 5eob | A | A | 6-[bis(fluoranyl)-[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl]methyl]quinoline | Human | 7100 | |
| MET | Met | TK | 3f66 | B | A | 3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol | Human | 3034 | |
| MET | Met | TK | 7b44 | A | B | 5-methoxy-1~{h}-indazole | Human | 13179 | |
| MET | Met | TK | 3l8v | A | | 2-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}amino)-n-(2,4-difluorophenyl)pyridine-3-carboxamide | Human | 2978 | |
| MET | Met | TK | 5hni | X | | methyl (6-{[6-(4-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1h-benzimidazol-2-yl)carbamate | Human | 7280 | |
| MET | Met | TK | 4knb | C | A | 7-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine | Human | 2955 | |
| MET | Met | TK | 6sdd | A | | n-{4-[(2-amino-3-chloropyridin-4-yl)oxy]-3-fluorophenyl}-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide | Human | 11533 | |
| MET | Met | TK | 3zbx | A | | 6-[[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl]methyl]quinoline | Human | 3036 | |
| MET | Met | TK | 5eyd | A | A | 6-[(1~{r})-1-[8-fluoranyl-6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(2-methoxyethoxy)-1,6-naphthyridin-5-one | Human | 6402 | |
| MET | Met | TK | 5ya5 | A | A | 2-[3-(4-methoxybenzyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]-1h-indole | Human | 10040 | |
| MET | Met | TK | 4gg5 | A | B | 3-(4-methylpiperazin-1-yl)-n-(3-nitrobenzyl)-7-(trifluoromethyl)quinolin-5-amine | Human | 2953 | |
| MET | Met | TK | 3f66 | A | B | 3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol | Human | 3027 | |
| MET | Met | TK | 2rfn | B | | 2-benzyl-5-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-3-methylpyrimidin-4(3h)-one | Human | 2961 | |
| MET | Met | TK | 4aoi | A | | 4-[3-(1h-pyrrolo[2,3-b]pyridin-3-ylmethyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-6-yl]benzenecarbonitrile | Human | 2958 | |
| MET | Met | TK | 7b3w | A | A | 3-(6-fluoranyl-1~{h}-indazol-4-yl)-4,5-dihydro-1~{h}-pyrrolo[3,4-b]pyrrol-6-one | Human | 13180 | |
| MET | Met | TK | 2wd1 | A | A | 1-[(2-nitrophenyl)sulfonyl]-1h-pyrrolo[3,2-b]pyridine-6-carboxamide | Human | 3032 | |
| MET | Met | TK | 4deg | A | | 7-methoxy-n-{[6-(3-methyl-1,2-thiazol-5-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}-1,5-naphthyridin-4-amine | Human | 2981 | |
| MET | Met | TK | 7b3z | A | A | 3-[3-(phenylmethyl)-1~{h}-pyrrolo[2,3-b]pyridin-5-yl]-4,5-dihydro-1~{h}-pyrrolo[3,4-b]pyrrol-6-one | Human | 13181 | |
| MET | Met | TK | 7b3q | A | B | 1-(phenylmethyl)-5~{h}-pyrrolo[3,2-c]pyridin-4-one | Human | 13182 | |
| MET | Met | TK | 6ubw | A | | n-(6-{difluoro[6-(1-methyl-1h-pyrazol-4-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]methyl}imidazo[1,2-b]pyridazin-2-yl)cyclopropanecarboxamide | Human | 11979 | |
| MET | Met | TK | 4gg7 | A | B | n-(3-nitrobenzyl)-6-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]-2-(trifluoromethyl)pyrido[2,3-d]pyrimidin-4-amine | Human | 2987 | |
| MET | Met | TK | 7b3t | A | A | 3-(phenylmethyl)-1~{h}-pyrrolo[2,3-b]pyridine | Human | 13183 | |
| MET | Met | TK | 7b41 | A | A | 3-[(2-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridine | Human | 13184 | |
| MET | Met | TK | 3zcl | A | | (s)-3-(1-(1h-pyrrolo(2,3-b)pyridin-3-yl)ethyl)-n-isopropyl-(1,2,4)triazolo(4,3-b)pyridazin-6-amine | Human | 2990 | |
| MET | Met | TK | 5uab | A | A | n-{6-[([1,2,4]triazolo[4,3-a]pyridin-3-yl)sulfanyl]imidazo[1,2-b]pyridazin-2-yl}cyclopropanecarboxamide | Human | 7961 | |
| MET | Met | TK | 5eob | A | B | 6-[bis(fluoranyl)-[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl]methyl]quinoline | Human | 7101 | |
| MET | Met | TK | 3f66 | B | C | 3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol | Human | 2966 | |
| MET | Met | TK | 3dkf | A | B | 6-{[6-(1-methyl-1h-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline | Human | 3029 | |
| MET | Met | TK | 4r1v | A | B | 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile | Human | 2972 | |
| MET | Met | TK | 6sd9 | A | | n-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 11531 | |
| MET | Met | TK | 1r0p | A | | k-252a | Human | 2991 | |
| MET | Met | TK | 3qti | A | B | 6-{[6-(1-methyl-1h-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]methyl}quinoline | Human | 3028 | |
| MET | Met | TK | 4gg5 | A | A | 3-(4-methylpiperazin-1-yl)-n-(3-nitrobenzyl)-7-(trifluoromethyl)quinolin-5-amine | Human | 2956 | |
| MET | Met | TK | 3dkf | A | C | 6-{[6-(1-methyl-1h-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline | Human | 2984 | |
| MET | Met | TK | 5hni | Y | | methyl (6-{[6-(4-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1h-benzimidazol-2-yl)carbamate | Human | 7278 | |
| MET | Met | TK | 5hoa | A | | 1-(6-{[6-(4-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1,3-benzothiazol-2-yl)-3-[2-(morpholin-4-yl)ethyl]urea | Human | 7279 | |
| MET | Met | TK | 4knb | C | B | 7-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine | Human | 3001 | |
| MET | Met | TK | 5hti | A | A | n-[3-fluoro-4-({7-[2-(morpholin-4-yl)ethoxy]-1,6-naphthyridin-4-yl}oxy)phenyl]-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 8010 | |
| MET | Met | TK | 7b44 | A | A | 5-methoxy-1~{h}-indazole | Human | 13185 | |
| MET | Met | TK | 3ce3 | A | | 1-(4-fluorophenyl)-n-[3-fluoro-4-(1h-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide | Human | 6769 | |
| MET | Met | TK | 4eev | A | B | n-(3-fluoro-4-{[1-methyl-6-(1h-pyrazol-4-yl)-1h-indazol-5-yl]oxy}phenyl)-1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide | Human | 3023 | |
| MET | Met | TK | 3dkc | A | A | adenosine-5'-triphosphate | Human | 2997 | |
| MET | Met | TK | 3vw8 | A | | n-({4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}carbamothioyl)-2-phenylacetamide | Human | 2985 | |
| MET | Met | TK | 3q6w | A | | 3-{5-oxo-3-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]-5h-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl}-n-(pyridin-2-ylmethyl)propanamide | Human | 2969 | |
| MET | Met | TK | 7b3z | A | B | 3-[3-(phenylmethyl)-1~{h}-pyrrolo[2,3-b]pyridin-5-yl]-4,5-dihydro-1~{h}-pyrrolo[3,4-b]pyrrol-6-one | Human | 13186 | |
| MET | Met | TK | 4xyf | A | B | 6-{(1s)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(2-methoxyethoxy)quinoline | Human | 2982 | |
| MET | Met | TK | 7b43 | B | | 3-[(4-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridine | Human | 13187 | |
| MET | Met | TK | 3q6u | A | A | - | Human | 2954 | |
| MET | Met | TK | 1r1w | A | | - | Human | 3014 | |
| MET | Met | TK | 7b3v | A | A | 3-(3-methyl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)-1~{h}-pyrrolo[3,4-b]pyrrol-6-one | Human | 13188 | |
| MET | Met | TK | 3f66 | A | C | 3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol | Human | 3011 | |
| MET | Met | TK | 5eyc | A | B | 6-[(1~{r})-1-[8-fluoranyl-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one | Human | 6400 | |
| MET | Met | TK | 3rhk | B | | 1-[(3r,4r)-4-(1h-indol-3-yl)-2,5-dioxopyrrolidin-3-yl]pyrrolo[3,2,1-ij]quinolinium | Human | 2959 | |
| MET | Met | TK | 3dkg | A | C | 6-{[6-(1-methyl-1h-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline | Human | 3006 | |
| MET | Met | TK | 5uad | A | | n-(6-{[6-(1-methyl-1h-pyrazol-4-yl)-1h-benzotriazol-1-yl]methyl}imidazo[1,2-b]pyridazin-2-yl)cyclopropanecarboxamide | Human | 7963 | |
| MET | Met | TK | 4knb | D | B | 7-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine | Human | 2968 | |
| MET | Met | TK | 3ccn | A | | 4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]phenol | Human | 2971 | |
| MET | Met | TK | 2rfn | A | | 2-benzyl-5-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-3-methylpyrimidin-4(3h)-one | Human | 3022 | |
| MET | Met | TK | 3zxz | A | | 2-{4-[1-(quinolin-6-ylmethyl)-1h-[1,2,3]triazolo[4,5-b]pyrazin-6-yl]-1h-pyrazol-1-yl}ethanol | Human | 2999 | |
| MET | Met | TK | 5hlw | A | | 1-[2-(1-ethylpiperidin-4-yl)ethyl]-3-(6-{[6-(thiophen-2-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1,3-benzothiazol-2-yl)urea | Human | 7275 | |
| MET | Met | TK | 4ap7 | A | | 4-[[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl]methyl]phenol | Human | 3035 | |
| MET | Met | TK | 2g15 | A | | - | Human | 2983 | |
| MET | Met | TK | 4knb | A | A | 7-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine | Human | 2960 | |
| MET | Met | TK | 4mxc | A | A | n-(3-fluoro-4-{[2-({3-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 3033 | |
| MET | Met | TK | 3f82 | A | | n-{4-[(2-amino-3-chloropyridin-4-yl)oxy]-3-fluorophenyl}-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide | Human | 2977 | |
| MET | Met | TK | 3q6u | A | B | - | Human | 2962 | |
| MET | Met | TK | 3zze | A | | (2s)-n'-[(3r)-4-chloro-7-methyl-2-oxo-2,3-dihydro-1h-indol-3-yl]-2-(4-hydroxyphenyl)propanehydrazide | Human | 2980 | |
| MET | Met | TK | 3dkc | A | B | adenosine-5'-triphosphate | Human | 2952 | |
| MET | Met | TK | 3f66 | A | D | 3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol | Human | 3026 | |
| MET | Met | TK | 3qti | B | A | 6-{[6-(1-methyl-1h-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]methyl}quinoline | Human | 3017 | |
| MET | Met | TK | 5t3q | A | | n-{3-fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl}-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazole-4-carboxamide | Human | 7413 | |
| MET | Met | TK | 5ho6 | A | | 1-(6-{[6-(4-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1,3-benzothiazol-2-yl)-3-[2-(morpholin-4-yl)ethyl]urea | Human | 7277 | |
| MET | Met | TK | 3efk | B | | 5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-2-[(4-fluorophenyl)amino]-3-methylpyrimidin-4(3h)-one | Human | 2988 | |
| MET | Met | TK | 3i5n | A | | 7-methoxy-n-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]-1,5-naphthyridin-4-amine | Human | 3013 | |
| MET | Met | TK | 3efj | A | | 2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-3-methylpyrimidin-4(3h)-one | Human | 3015 | |
| MET | Met | TK | 3r7o | A | | n-[(2r)-1,4-dioxan-2-ylmethyl]-n-methyl-n'-{5-oxo-3-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]-5h-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl}sulfuric diamide | Human | 3038 | |
| MET | Met | TK | 3dkg | A | A | 6-{[6-(1-methyl-1h-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline | Human | 2993 | |
| MET | Met | TK | 3efk | A | | 5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-2-[(4-fluorophenyl)amino]-3-methylpyrimidin-4(3h)-one | Human | 3018 | |
| MET | Met | TK | 5dg5 | A | B | n-(2,5-difluoro-4-{[2-(1-methyl-1h-pyrazol-4-yl)pyridin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 7034 | |
| MET | Met | TK | 2rfs | A | | n-(3-chlorophenyl)-n-methyl-2-oxo-3-[(3,4,5-trimethyl-1h-pyrrol-2-yl)methyl]-2h-indole-5-sulfonamide | Human | 2974 | |
| MET | Met | TK | 3cd8 | A | A | 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline | Human | 3008 | |
| MET | Met | TK | 3rhk | A | | 1-[(3r,4r)-4-(1h-indol-3-yl)-2,5-dioxopyrrolidin-3-yl]pyrrolo[3,2,1-ij]quinolinium | Human | 2979 | |
| MET | Met | TK | 4iwd | A | | 1-{5-oxo-3-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]-5h-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl}-n-(pyridin-2-ylmethyl)methanesulfonamide | Human | 2975 | |
| MET | Met | TK | 3c1x | A | | n-{[4-({5-[(4-aminopiperidin-1-yl)methyl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}oxy)-3-fluorophenyl]carbamoyl}-2-(4-fluorophenyl)acetamide | Human | 3020 | |
| MET | Met | TK | 2wkm | A | | (3z)-5-[(2,6-dichlorobenzyl)sulfonyl]-3-[(3,5-dimethyl-4-{[(2s)-2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]carbonyl}-1h-pyrrol-2-yl)methylidene]-1,3-dihydro-2h-indol-2-one | Human | 3021 | |
| MET | Met | TK | 6sdc | A | B | n-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 11534 | |
| MET | Met | TK | 7b40 | A | | 3-(phenylmethyl)-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridine | Human | 13192 | |
| MET | Met | TK | 4dei | A | | 3-{(1s)-1-[3-(2-methoxyethoxy)quinolin-6-yl]ethyl}-5-(3-methyl-1,2-thiazol-5-yl)-3,5-dihydro-4h-[1,2,3]triazolo[4,5-c]pyridin-4-one | Human | 3016 | |
| MET | Met | TK | 4knb | D | A | 7-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine | Human | 3010 | |
| MET | Met | TK | 4xmo | A | | 6-{(1r)-1-fluoro-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-methoxyquinoline | Human | 3031 | |
| MET | Met | TK | 5ya5 | A | B | 2-[3-(4-methoxybenzyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]-1h-indole | Human | 10039 | |
| MET | Met | TK | 3ctj | A | B | 2-(4-fluorophenyl)-n-{[3-fluoro-4-(1h-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide | Human | 6766 | |
| MET | Met | TK | 7b41 | A | B | 3-[(2-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridine | Human | 13193 | |
