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Search results (176 entries covering 89 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
IRAK4IRAKTKL4u9aBstaurosporineHuman17920.64
IRAK4IRAKTKL4u9aAstaurosporineHuman17510.64
SYKSykTK1xbcAAstaurosporineHuman11650.64
DYRK1ADYRKCMGC4nctApkc412Human37940.62
IRAK4IRAKTKL2oicAstaurosporineHuman17390.64
ERN1 (IRE1)IREOther4yzcBBstaurosporineHuman62310.64
STK16 (MPSK1)NAKOther2bujAstaurosporineHuman22290.64
LCKSrcTK1qpjAstaurosporineHuman22830.64
MAP3K5STE11STE4bf2AstaurosporineHuman47430.64
CSKCskTK1bygAstaurosporineHuman29430.64
STK16 (MPSK1)NAKOther2bujBstaurosporineHuman22300.64
MAP3K5STE11STE2clqBBstaurosporineHuman47320.64
IRAK4IRAKTKL2oicDstaurosporineHuman17550.64
EPHB4 (EphB4)EphTK2yn8BstaurosporineHuman3490.64
CHEK1 (CHK1)CAMKLCAMK7akoBAstaurosporineHuman134920.64
PRKAA2 (AMPKa2)CAMKLCAMK6b1uCAstaurosporineHuman98470.64
PIK3CG (p110g)PIKAtypical1e8zAstaurosporineHuman92280.64
MAP3K5STE11STE2clqABstaurosporineHuman47360.64
EGFREGFRTK5xgnA12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5h-indolo[2,3-a]pyrrolo[3,4-c]carbazoleHuman85530.43
EGFREGFRTK5xgmA12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5h-indolo[2,3-a]pyrrolo[3,4-c]carbazoleHuman85520.43
LIMK1LISKTKL3s95AAstaurosporineHuman12460.64
LIMK1LISKTKL3s95ABstaurosporineHuman12480.64
IRAK4IRAKTKL2nryDAstaurosporineHuman17890.64
PDPK1 (PDK1)PDK1AGC1okzA7-hydroxystaurosporineHuman32090.47
PRKAA1 (AMPKa1)CAMKLCAMK6c9jAstaurosporineHuman107170.64
PRKAA1 (AMPKa1)CAMKLCAMK4rerAstaurosporineHuman1210.64
PRKAA1 (AMPKa1)CAMKLCAMK4rewAstaurosporineHuman1240.64
PRKAA1 (AMPKa1)CAMKLCAMK6c9hAstaurosporineHuman107140.64
PRKAA1 (AMPKa1)CAMKLCAMK6c9gAstaurosporineHuman107150.64
PRKAA1 (AMPKa1)CAMKLCAMK6c9fAstaurosporineHuman107160.64
PDPK1 (PDK1)PDK1AGC1okyAAstaurosporineHuman31640.64
IRAK4IRAKTKL2nryBAstaurosporineHuman17580.64
Prkaa1 (AMPKa1)CAMKLCAMK5ufuAstaurosporineMouse75900.64
CDK2CDKCMGC4ez7AstaurosporineHuman42400.64
PAK4STE20STE5vedAstaurosporineHuman85700.64
ERN1 (IRE1)IREOther4yzcAAstaurosporineHuman62350.64
IRAK4IRAKTKL2nryCAstaurosporineHuman17790.64
GSK3BGSKCMGC1q3dBstaurosporineHuman7520.64
TGFBR1 (TGFbR1)STKRTKL5e8wAAstaurosporineHuman66110.64
MAP2K1STE7STE3eqfAk-252aHuman33171.00
EPHB4 (EphB4)EphTK2yn8AstaurosporineHuman3520.64
EPHB4 (EphB4)EphTK3zewBBstaurosporineHuman3570.64
SYKSykTK1xbcABstaurosporineHuman12070.64
DYRK1ADYRKCMGC4nctCpkc412Human37790.62
PKN1PKNAGC4otgAAlestaurtinibHuman5480.49
STK32A (YANK1)YANKAGC4fr4ABstaurosporineHuman46900.64
ERN1 (IRE1)IREOther4yzcABstaurosporineHuman62320.64
CHEK1 (CHK1)CAMKLCAMK7akoABstaurosporineHuman134950.64
CHEK1 (CHK1)CAMKLCAMK5oorAstaurosporineHuman86030.64
RIPK2RIPKTKL5ng2ABstaurosporineHuman80560.64
RIPK2RIPKTKL5ng2AAstaurosporineHuman80500.64
CHEK1 (CHK1)CAMKLCAMK1nvsArel-(9r,12s)-9,10,11,12-tetrahydro-9,12-epoxy-1h-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2h)-dioneHuman15910.43
CHEK1 (CHK1)CAMKLCAMK1nvrAstaurosporineHuman15850.64
CDK2CDKCMGC7nvqAstaurosporineHuman136270.64
STK24 (MST3)STE20STE3ckxAstaurosporineHuman55990.64
STK24 (MST3)STE20STE4qmyAstaurosporineHuman55920.64
RPS6KA1 (RSK3)RSKAGC2z7rAstaurosporineHuman27770.64
CHEK1 (CHK1)CAMKLCAMK1nvqA7-hydroxystaurosporineHuman16420.47
MELKCAMKLCAMK5m5aAAk-252aHuman87351.00
STK32A (YANK1)YANKAGC4fr4EBstaurosporineHuman46850.64
LCKSrcTK1qpdAstaurosporineHuman22670.64
MAP3K5STE11STE2clqAAstaurosporineHuman47400.64
MAPKAPK2MAPKAPKCAMK1nxkAstaurosporineHuman13420.64
CDK2CDKCMGC1pkdA7-hydroxystaurosporineHuman41700.47
MKNK2 (MNK2)MAPKAPKCAMK2hw7AstaurosporineHuman7640.64
MAP2K6STE7STE3fmeAstaurosporineHuman12310.64
PRKAA2 (AMPKa2)CAMKLCAMK6b1uCBstaurosporineHuman98500.64
PRKAA2 (AMPKa2)CAMKLCAMK5isoCstaurosporineHuman79800.64
PRKAA2 (AMPKa2)CAMKLCAMK5ezvCBstaurosporineHuman64260.64
PRKAA2 (AMPKa2)CAMKLCAMK5ezvAAstaurosporineHuman64240.64
PRKAA2 (AMPKa2)CAMKLCAMK4cffCstaurosporineHuman1900.64
PRKAA2 (AMPKa2)CAMKLCAMK6b2eAstaurosporineHuman98510.64
AAK1NAKOther4wsqBAk-252aHuman38331.00
AAK1NAKOther4wsqBBk-252aHuman38351.00
PRKAA2 (AMPKa2)CAMKLCAMK6b1uAAstaurosporineHuman98480.64
PRKAA2 (AMPKa2)CAMKLCAMK5isoAstaurosporineHuman79810.64
PRKAA2 (AMPKa2)CAMKLCAMK5ezvCAstaurosporineHuman64300.64
AAK1NAKOther4wsqAAk-252aHuman38341.00
TGFBR2 (TGFbR2)STKRTKL5e8yAstaurosporineHuman66270.64
AAK1NAKOther4wsqABk-252aHuman38361.00
TTKTTKOther3hmoAstaurosporineHuman47070.64
MELKCAMKLCAMK5m5aABk-252aHuman87331.00
PIM1PIMCAMK1yhsAstaurosporineHuman24440.64
FESFerTK3cd3AAstaurosporineHuman28140.64
FESFerTK3cblABstaurosporineHuman28110.64
IRAK4IRAKTKL2nryAAstaurosporineHuman17530.64
FESFerTK3bkbAAstaurosporineHuman28100.64
FESFerTK3bkbABstaurosporineHuman28130.64
CDK2CDKCMGC1aq1AstaurosporineHuman42670.64
FESFerTK3cd3ABstaurosporineHuman28150.64
ERN1 (IRE1)IREOther4yzcBAstaurosporineHuman62270.64
PRKAA2 (AMPKa2)CAMKLCAMK4cfeCstaurosporineHuman1920.64
EPHB4 (EphB4)EphTK3zewABstaurosporineHuman3770.64
PRKAA2 (AMPKa2)CAMKLCAMK4cffAstaurosporineHuman1910.64
EPHB4 (EphB4)EphTK3zewBAstaurosporineHuman3510.64
CDK2CDKCMGC1pkdC7-hydroxystaurosporineHuman39730.47
Ripk4 (ANKRD3)RIPKTKL5wnjAlestaurtinibMouse98930.49
Ripk4 (ANKRD3)RIPKTKL5wnlAstaurosporineMouse98910.64
CDK2CDKCMGC4erwAstaurosporineHuman43700.64
LYNSrcTK3a4oXstaurosporineHuman18120.64
ZAP70SykTK1u59AAstaurosporineHuman27340.64
DYRK1ADYRKCMGC4nctDpkc412Human37510.62
ZAP70SykTK1u59ABstaurosporineHuman27330.64
DYRK1ADYRKCMGC4nctBpkc412Human37430.62
JAK2JakATK8bpwABlestaurtinibHuman150390.49
JAK2JakATK8bpwAAlestaurtinibHuman150440.49
RIPK2RIPKTKL5ng2BAstaurosporineHuman80530.64
RIPK2RIPKTKL5ng2BBstaurosporineHuman80520.64
IRAK4IRAKTKL4u97AstaurosporineHuman17540.64
JAK3JakATK1yvjAA1,2,3,4-tetrahydrogen-staurosporineHuman4600.54
MASTLMASTAGC5lohBAstaurosporineHuman70880.64
MASTLMASTAGC5lohBBstaurosporineHuman70870.64
MASTLMASTAGC5lohABstaurosporineHuman70850.64
MASTLMASTAGC5lohAAstaurosporineHuman70860.64
FESFerTK3cblAAstaurosporineHuman28080.64
ABL1AblTK2hz4B1,2,3,4-tetrahydrogen-staurosporineHuman10580.54
JAK3JakATK1yvjAB1,2,3,4-tetrahydrogen-staurosporineHuman4510.54
GSK3BGSKCMGC1q3dAstaurosporineHuman7050.64
ALKALKTK3lcsAAstaurosporineHuman53810.64
MAP3K5STE11STE2clqBAstaurosporineHuman47550.64
MAP3K5STE11STE4bf2BstaurosporineHuman47450.64
ALKALKTK3lcsABstaurosporineHuman53760.64
TGFBR1 (TGFbR1)STKRTKL5e8xABstaurosporineHuman66170.64
STK32A (YANK1)YANKAGC4fr4BAstaurosporineHuman46920.64
STK32A (YANK1)YANKAGC4fr4CAstaurosporineHuman46840.64
IRAK4IRAKTKL2oicBstaurosporineHuman17520.64
PDPK1 (PDK1)PDK1AGC1okyABstaurosporineHuman31950.64
IRAK4IRAKTKL4u97BstaurosporineHuman17420.64
LIMK1LISKTKL3s95BBstaurosporineHuman12470.64
LIMK1LISKTKL3s95BAstaurosporineHuman12450.64
PRKCQ (PKCt)PKCAGC1xjdAstaurosporineHuman53570.64
ITKTecTK1sm2AstaurosporineHuman740.64
ITKTecTK1snuAstaurosporineHuman820.64
IRAK4IRAKTKL2nryDBstaurosporineHuman17460.64
ITKTecTK1sm2BstaurosporineHuman730.64
IRAK4IRAKTKL2nryCBstaurosporineHuman17500.64
ITKTecTK1snuBstaurosporineHuman330.64
CHEK1 (CHK1)CAMKLCAMK7akoAAstaurosporineHuman134900.64
IRAK4IRAKTKL2nryBBstaurosporineHuman17720.64
IRAK4IRAKTKL2oicCstaurosporineHuman17340.64
IRAK4IRAKTKL2nryABstaurosporineHuman17770.64
STK32A (YANK1)YANKAGC4fr4BBstaurosporineHuman46950.64
PKN1PKNAGC4otgABlestaurtinibHuman5490.49
STK32A (YANK1)YANKAGC4fr4FBstaurosporineHuman46860.64
CSKCskTK3d7tAstaurosporineHuman29410.64
DAPK1DAPKCAMK1wvyAstaurosporineHuman56610.64
STK32A (YANK1)YANKAGC4fr4EAstaurosporineHuman46890.64
STK32A (YANK1)YANKAGC4fr4CBstaurosporineHuman46940.64
STK32A (YANK1)YANKAGC4fr4DAstaurosporineHuman46880.64
STK32A (YANK1)YANKAGC4fr4FAstaurosporineHuman46910.64
EPHB4 (EphB4)EphTK3zewAAstaurosporineHuman3730.64
CHEK1 (CHK1)CAMKLCAMK7akoBBstaurosporineHuman134960.64
STK32A (YANK1)YANKAGC4fr4DBstaurosporineHuman46870.64
STK32A (YANK1)YANKAGC4fr4AAstaurosporineHuman46930.64
MAPKAPK2MAPKAPKCAMK1nxkCstaurosporineHuman13120.64
MAPKAPK2MAPKAPKCAMK1nxkDstaurosporineHuman13340.64
MAPKAPK2MAPKAPKCAMK2pzyCstaurosporineHuman12790.64
MAPKAPK2MAPKAPKCAMK1nxkBstaurosporineHuman12920.64
FESFerTK3bkbACstaurosporineHuman28120.64
PAK1STE20STE2hy81(5s,6r,7r,9r)-12-hydroxy-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9-tetrahydro-5h,14h-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-oneHuman1720.42
IKBKB (IKKb)IKKOther4kikBBk-252aHuman2931.00
IKBKB (IKKb)IKKOther4kikAAk-252aHuman2901.00
IKBKB (IKKb)IKKOther4kikBAk-252aHuman2951.00
IKBKB (IKKb)IKKOther4kikABk-252aHuman2881.00
FYNSrcTK2dq7XstaurosporineHuman19410.64
TGFBR1 (TGFbR1)STKRTKL5e8wABstaurosporineHuman66140.64
RPS6KB1 (p70S6K)RSKAGC3a62AstaurosporineHuman18670.64
TGFBR1 (TGFbR1)STKRTKL5e8xAAstaurosporineHuman66150.64
RPS6KB1 (p70S6K)RSKAGC3a61AstaurosporineHuman18460.64
RPS6KB1 (p70S6K)RSKAGC4rloBstaurosporineHuman72200.64
RPS6KB1 (p70S6K)RSKAGC3a60BstaurosporineHuman18560.64
RPS6KB1 (p70S6K)RSKAGC3a60AstaurosporineHuman18520.64
METMetTK1r0pAk-252aHuman29911.00
PRKAA2 (AMPKa2)CAMKLCAMK6b1uABstaurosporineHuman98490.64
PRKAA2 (AMPKa2)CAMKLCAMK4cfeAstaurosporineHuman1950.64
PRKAA2 (AMPKa2)CAMKLCAMK5ezvABstaurosporineHuman64280.64
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